CN110799546A - 重组双特异性抗体 - Google Patents
重组双特异性抗体 Download PDFInfo
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Abstract
提供了一种针对CTLA‑4和PDL‑1的重组双特异性抗体，编码抗体的核酸分子，包含该核酸分子的载体和宿主细胞，以及制备该抗体的方法。还提供了包含该双特异性抗体的药物组合物，以及该双特异性抗体在制备药物组合物中的用途。
Description
PCT国内申请，说明书已公开。
Claims (29)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2017107814023 | 2017-09-01 | ||
| CN201710781402 | 2017-09-01 | ||
| PCT/CN2018/100971 WO2019042153A1 (zh) | 2017-09-01 | 2018-08-17 | 重组双特异性抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110799546A true CN110799546A (zh) | 2020-02-14 |
| CN110799546B CN110799546B (zh) | 2023-01-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880041765.6A Active CN110799546B (zh) | 2017-09-01 | 2018-08-17 | 重组双特异性抗体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11421029B2 (zh) |
| EP (1) | EP3626745A4 (zh) |
| JP (1) | JP7145895B2 (zh) |
| KR (1) | KR102678252B1 (zh) |
| CN (1) | CN110799546B (zh) |
| WO (1) | WO2019042153A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113993903A (zh) * | 2020-05-15 | 2022-01-28 | 三生国健药业（上海）股份有限公司 | 一种抗pd-1和pd-l1的四价双特异性抗体 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3551660T (pt) | 2016-12-07 | 2023-11-30 | Ludwig Inst For Cancer Res Ltd | Anticorpos anti-ctla-4 e métodos de uso dos mesmos |
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| KR20200041835A (ko) | 2020-04-22 |
| CN110799546B (zh) | 2023-01-24 |
| JP7145895B2 (ja) | 2022-10-03 |
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| EP3626745A4 (en) | 2021-03-17 |
| JP2020534791A (ja) | 2020-12-03 |
| US20200216538A1 (en) | 2020-07-09 |
| EP3626745A1 (en) | 2020-03-25 |
| KR102678252B1 (ko) | 2024-06-26 |
| US11421029B2 (en) | 2022-08-23 |
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