CN110770346B - 多倍体腺相关病毒载体及其制备和使用方法 - Google Patents

多倍体腺相关病毒载体及其制备和使用方法 Download PDF

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CN110770346B
CN110770346B CN201880031964.9A CN201880031964A CN110770346B CN 110770346 B CN110770346 B CN 110770346B CN 201880031964 A CN201880031964 A CN 201880031964A CN 110770346 B CN110770346 B CN 110770346B
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aav
capsid
transduction
viral
aav8
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CN110770346A (zh
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R.J.萨穆尔斯基
C.李
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University of North Carolina at Chapel Hill
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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CN201880031964.9A 2017-03-15 2018-03-15 多倍体腺相关病毒载体及其制备和使用方法 Active CN110770346B (zh)

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US201762471762P 2017-03-15 2017-03-15
US62/471762 2017-03-15
US201762520901P 2017-06-16 2017-06-16
US62/520901 2017-06-16
US201862630558P 2018-02-14 2018-02-14
US62/630558 2018-02-14
PCT/US2018/022725 WO2018170310A1 (en) 2017-03-15 2018-03-15 Polyploid adeno-associated virus vectors and methods of making and using the same

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CA (1) CA3054711A1 (https=)
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IL (3) IL316259A (https=)
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WO2012112578A2 (en) * 2011-02-14 2012-08-23 The Children's Hospital Of Philadelphia Improved aav8 vector with enhanced functional activity and methods of use thereof
US20150023924A1 (en) * 2013-07-22 2015-01-22 The Children's Hospital Of Philadelphia Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues

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