CN110691599B - 使用脂多糖的脑功能改善剂、食品和药品 - Google Patents

使用脂多糖的脑功能改善剂、食品和药品 Download PDF

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Publication number
CN110691599B
CN110691599B CN201780091325.7A CN201780091325A CN110691599B CN 110691599 B CN110691599 B CN 110691599B CN 201780091325 A CN201780091325 A CN 201780091325A CN 110691599 B CN110691599 B CN 110691599B
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brain
lipopolysaccharide
group
pantoea
food
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Chinese (zh)
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CN110691599A (zh
Inventor
杣源一郎
稻川裕之
河内千惠
小林优多郎
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Research Combination Of Natural Immune Control Technology
Biomedical Research Group Inc
Kagawa University NUC
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Research Combination Of Natural Immune Control Technology
Biomedical Research Group Inc
Kagawa University NUC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201780091325.7A 2017-05-28 2017-12-04 使用脂多糖的脑功能改善剂、食品和药品 Active CN110691599B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017105133A JP6998133B2 (ja) 2017-05-28 2017-05-28 リポ多糖を用いた脳機能改善剤、食品及び医薬品
JP2017-105133 2017-05-28
PCT/JP2017/043429 WO2018220886A1 (ja) 2017-05-28 2017-12-04 リポ多糖を用いた脳機能改善剤、食品及び医薬品

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CN110691599A CN110691599A (zh) 2020-01-14
CN110691599B true CN110691599B (zh) 2023-05-02

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Country Link
US (1) US11278564B2 (enExample)
EP (1) EP3643314B1 (enExample)
JP (2) JP6998133B2 (enExample)
KR (2) KR20200011490A (enExample)
CN (1) CN110691599B (enExample)
BR (1) BR112019024953A2 (enExample)
IL (1) IL270936B2 (enExample)
WO (1) WO2018220886A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6998133B2 (ja) * 2017-05-28 2022-01-18 自然免疫制御技術研究組合 リポ多糖を用いた脳機能改善剤、食品及び医薬品
WO2022104088A2 (en) * 2020-11-13 2022-05-19 National Health Research Institutes Method for treating amyloidogenic disease
JP7679216B2 (ja) * 2021-04-07 2025-05-19 有限会社バイオメディカルリサーチグループ リポ多糖製造方法、リポ多糖、及びその配合物
AU2022464309A1 (en) 2022-06-22 2025-01-23 Biomedical Research Group Inc. Prophylactic drug and therapeutic drug for diabetes-associated dementia
KR102555274B1 (ko) 2022-12-03 2023-07-13 김환배 분리형 측면 미세먼지 집진휀스로 세척이 용이한 고기구이기

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106714827A (zh) * 2014-10-02 2017-05-24 日东电工株式会社 经皮给药用疫苗药物组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005030938A1 (ja) 2003-09-26 2005-04-07 Biomedical Research Group Inc. 発酵及び培養方法、植物発酵エキス、植物発酵エキス末並びに該植物発酵エキス配合物
JP2016193865A (ja) 2015-03-31 2016-11-17 キリン株式会社 ミクログリア貪食活性亢進のための組成物及びミクログリア貪食活性亢進作用の予測方法
JP6780240B2 (ja) 2015-12-11 2020-11-04 株式会社リコー 制御装置、液体を吐出する装置、印刷物の生産方法及びプログラム
JP6998133B2 (ja) 2017-05-28 2022-01-18 自然免疫制御技術研究組合 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106714827A (zh) * 2014-10-02 2017-05-24 日东电工株式会社 经皮给药用疫苗药物组合物

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway;Masahiro Fukasaka等;《pone》;20150515;全文 *
A mixture of Salacia oblonga extract and IP-PA1 reduces fasting plasma glucose (FPG) and low-density lipoprotein (LDL) cholesterol levels;Kazue Nakata等;《Nutrition Research and Practice》;20111231;全文 *
Effect of Lipopolysaccharide Derived from Pantoea agglomerans on the Phagocytic Activity of Amyloid β by Primary Murine Microglial Cells;YUTARO KOBAYASHI等;《ANTICANCER RESEARCH》;20161231;第3693-3698页 *
Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer’s disease-related pathology;Jean-Philippe Michaud等;《PNAS》;20130129;全文 *

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Publication number Publication date
BR112019024953A2 (pt) 2020-06-23
EP3643314C0 (en) 2023-08-30
KR20220025912A (ko) 2022-03-03
IL270936A (en) 2020-01-30
KR20200011490A (ko) 2020-02-03
EP3643314A4 (en) 2021-04-07
JP2018199643A (ja) 2018-12-20
EP3643314A1 (en) 2020-04-29
CN110691599A (zh) 2020-01-14
US20200179436A1 (en) 2020-06-11
US11278564B2 (en) 2022-03-22
JP2021169506A (ja) 2021-10-28
JP6998133B2 (ja) 2022-01-18
WO2018220886A1 (ja) 2018-12-06
IL270936B2 (en) 2023-10-01
IL270936B1 (en) 2023-06-01
EP3643314B1 (en) 2023-08-30
JP7809461B2 (ja) 2026-02-02

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