JP6998133B2 - リポ多糖を用いた脳機能改善剤、食品及び医薬品 - Google Patents

リポ多糖を用いた脳機能改善剤、食品及び医薬品 Download PDF

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JP6998133B2
JP6998133B2 JP2017105133A JP2017105133A JP6998133B2 JP 6998133 B2 JP6998133 B2 JP 6998133B2 JP 2017105133 A JP2017105133 A JP 2017105133A JP 2017105133 A JP2017105133 A JP 2017105133A JP 6998133 B2 JP6998133 B2 JP 6998133B2
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brain
food
brain function
pantoea
lps
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JP2018199643A5 (enExample
JP2018199643A (ja
Inventor
源一郎 杣
裕之 稲川
千恵 河内
優多郎 小林
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CONTROL OF INNATE IMMUNITY TECHNOLOGY RESEARCH ASSOCIATION
Biomedical Research Group Inc
Kagawa University NUC
Macrophi Inc
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CONTROL OF INNATE IMMUNITY TECHNOLOGY RESEARCH ASSOCIATION
Biomedical Research Group Inc
Kagawa University NUC
Macrophi Inc
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Priority to JP2017105133A priority Critical patent/JP6998133B2/ja
Application filed by CONTROL OF INNATE IMMUNITY TECHNOLOGY RESEARCH ASSOCIATION, Biomedical Research Group Inc, Kagawa University NUC, Macrophi Inc filed Critical CONTROL OF INNATE IMMUNITY TECHNOLOGY RESEARCH ASSOCIATION
Priority to CN201780091325.7A priority patent/CN110691599B/zh
Priority to IL270936A priority patent/IL270936B2/en
Priority to EP17911728.8A priority patent/EP3643314B1/en
Priority to BR112019024953-2A priority patent/BR112019024953A2/pt
Priority to KR1020197038343A priority patent/KR20200011490A/ko
Priority to PCT/JP2017/043429 priority patent/WO2018220886A1/ja
Priority to KR1020227004771A priority patent/KR20220025912A/ko
Priority to US16/617,540 priority patent/US11278564B2/en
Publication of JP2018199643A publication Critical patent/JP2018199643A/ja
Publication of JP2018199643A5 publication Critical patent/JP2018199643A5/ja
Priority to JP2021117563A priority patent/JP2021169506A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2017105133A 2017-05-28 2017-05-28 リポ多糖を用いた脳機能改善剤、食品及び医薬品 Active JP6998133B2 (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2017105133A JP6998133B2 (ja) 2017-05-28 2017-05-28 リポ多糖を用いた脳機能改善剤、食品及び医薬品
US16/617,540 US11278564B2 (en) 2017-05-28 2017-12-04 Brain function-improving agent, food, and medicine using lipopolysaccharide
EP17911728.8A EP3643314B1 (en) 2017-05-28 2017-12-04 Brain function-improving agent, food, and medicine using lipopolysaccharide
BR112019024953-2A BR112019024953A2 (pt) 2017-05-28 2017-12-04 Agente, alimento ou medicamento para melhorar a função cerebral
KR1020197038343A KR20200011490A (ko) 2017-05-28 2017-12-04 리포 다당을 사용한 뇌기능 개선제, 식품 및 의약품
PCT/JP2017/043429 WO2018220886A1 (ja) 2017-05-28 2017-12-04 リポ多糖を用いた脳機能改善剤、食品及び医薬品
CN201780091325.7A CN110691599B (zh) 2017-05-28 2017-12-04 使用脂多糖的脑功能改善剂、食品和药品
IL270936A IL270936B2 (en) 2017-05-28 2017-12-04 Brain function-improving agent, food, and medicine using lipopolysaccharide
KR1020227004771A KR20220025912A (ko) 2017-05-28 2017-12-04 리포 다당을 사용한 뇌기능 개선제, 식품 및 의약품
JP2021117563A JP2021169506A (ja) 2017-05-28 2021-07-16 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017105133A JP6998133B2 (ja) 2017-05-28 2017-05-28 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Related Child Applications (1)

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JP2021117563A Division JP2021169506A (ja) 2017-05-28 2021-07-16 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Publications (3)

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JP2018199643A JP2018199643A (ja) 2018-12-20
JP2018199643A5 JP2018199643A5 (enExample) 2020-05-14
JP6998133B2 true JP6998133B2 (ja) 2022-01-18

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JP2017105133A Active JP6998133B2 (ja) 2017-05-28 2017-05-28 リポ多糖を用いた脳機能改善剤、食品及び医薬品
JP2021117563A Pending JP2021169506A (ja) 2017-05-28 2021-07-16 リポ多糖を用いた脳機能改善剤、食品及び医薬品

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JP2021117563A Pending JP2021169506A (ja) 2017-05-28 2021-07-16 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Country Status (8)

Country Link
US (1) US11278564B2 (enExample)
EP (1) EP3643314B1 (enExample)
JP (2) JP6998133B2 (enExample)
KR (2) KR20220025912A (enExample)
CN (1) CN110691599B (enExample)
BR (1) BR112019024953A2 (enExample)
IL (1) IL270936B2 (enExample)
WO (1) WO2018220886A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6998133B2 (ja) * 2017-05-28 2022-01-18 自然免疫制御技術研究組合 リポ多糖を用いた脳機能改善剤、食品及び医薬品
JP2023549503A (ja) * 2020-11-13 2023-11-27 ナショナル ヘルス リサーチ インスティチューツ アミロイド原性疾患を処置する方法
JP7679216B2 (ja) * 2021-04-07 2025-05-19 有限会社バイオメディカルリサーチグループ リポ多糖製造方法、リポ多糖、及びその配合物
AU2022464309A1 (en) * 2022-06-22 2025-01-23 Biomedical Research Group Inc. Prophylactic drug and therapeutic drug for diabetes-associated dementia
KR102555274B1 (ko) 2022-12-03 2023-07-13 김환배 분리형 측면 미세먼지 집진휀스로 세척이 용이한 고기구이기

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4026722B2 (ja) 2003-09-26 2007-12-26 源一郎 杣 植物発酵エキス、植物発酵エキス末及び該植物発酵エキス配合物
TW201618790A (zh) * 2014-10-02 2016-06-01 Nitto Denko Corp 經皮投與用疫苗醫藥組合物
JP2016193865A (ja) 2015-03-31 2016-11-17 キリン株式会社 ミクログリア貪食活性亢進のための組成物及びミクログリア貪食活性亢進作用の予測方法
JP6780240B2 (ja) 2015-12-11 2020-11-04 株式会社リコー 制御装置、液体を吐出する装置、印刷物の生産方法及びプログラム
JP6998133B2 (ja) * 2017-05-28 2022-01-18 自然免疫制御技術研究組合 リポ多糖を用いた脳機能改善剤、食品及び医薬品

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
INAGAWA, Hiroyuki et al.，Primed Activation of Macrophages by Oral Administration of Lipopolysaccharide Derived from Pantoea a，in vivo，2016年，Vol.30，pp.205-211，ISSN:0258-851X, 特に第２１０頁左欄第２７行～第３６行
KOBAYASHI, Y. et al.，Effect of Lipopolysaccharide Derived from Pantoea agglomerans on the Phagocytic Activity of Amyloid，Anticancer Res.，2016年，Vol.36(7)，pp.3693-3698，ISSN:0250-7005, 特に「アブストラクト」、第３６９３頁右欄第１行～第７行、第１９行、第３６９３頁右欄第
池田幸矢 ほか，マクロファージ細胞株RAW264.7におけるPantoea agglomerans由来LPSの貪食能活性化に関する検討，バイオ治療法研究会学術集会プログラム・抄録集，2016年，第２０回，p.42，特に「背景・目的」欄

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Publication number Publication date
US11278564B2 (en) 2022-03-22
IL270936B1 (en) 2023-06-01
WO2018220886A1 (ja) 2018-12-06
CN110691599B (zh) 2023-05-02
CN110691599A (zh) 2020-01-14
BR112019024953A2 (pt) 2020-06-23
JP2018199643A (ja) 2018-12-20
IL270936A (en) 2020-01-30
IL270936B2 (en) 2023-10-01
US20200179436A1 (en) 2020-06-11
EP3643314A1 (en) 2020-04-29
KR20220025912A (ko) 2022-03-03
JP2021169506A (ja) 2021-10-28
EP3643314A4 (en) 2021-04-07
EP3643314C0 (en) 2023-08-30
EP3643314B1 (en) 2023-08-30
KR20200011490A (ko) 2020-02-03

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