CN110618208A - 一种(s)-(+)-3-羟基四氢呋喃对映异构体含量检测方法 - Google Patents
一种(s)-(+)-3-羟基四氢呋喃对映异构体含量检测方法 Download PDFInfo
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- CN110618208A CN110618208A CN201910850662.0A CN201910850662A CN110618208A CN 110618208 A CN110618208 A CN 110618208A CN 201910850662 A CN201910850662 A CN 201910850662A CN 110618208 A CN110618208 A CN 110618208A
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- hydroxytetrahydrofuran
- temperature
- ethyl acetate
- shaking
- dissolving
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
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CN201910850662.0A CN110618208A (zh) | 2019-09-10 | 2019-09-10 | 一种(s)-(+)-3-羟基四氢呋喃对映异构体含量检测方法 |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112630313A (zh) * | 2020-11-06 | 2021-04-09 | 天地恒一制药股份有限公司 | 一种(s)-3-羟基四氢呋喃对映异构体的高效液相拆分方法 |
CN113092629A (zh) * | 2021-04-14 | 2021-07-09 | 合肥利夫生物科技有限公司 | 一种s-(+)-3-羟基四氢呋喃的纯化和异构体检测方法 |
CN114354801A (zh) * | 2021-12-31 | 2022-04-15 | 山东大学 | (R)-3-Boc-氨基哌啶中三种氨基吡啶异构体含量的分析方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5234950A (en) * | 1988-12-23 | 1993-08-10 | Imperial Chemical Industries Plc | Tetrahydrofuran derivatives |
US5928515A (en) * | 1997-12-12 | 1999-07-27 | Uop Llc | Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers |
WO2007081065A1 (en) * | 2006-01-10 | 2007-07-19 | Sk Holdings Co., Ltd. | Method for preparing 3-hydroxytetrahydrofuran using cyclodehydration |
CN106957287A (zh) * | 2016-01-12 | 2017-07-18 | 杭州述康生物技术有限公司 | 一种药物中间体(s)-3-羟基四氢呋喃的制备方法 |
CN107935971A (zh) * | 2017-12-28 | 2018-04-20 | 山东铂源药业有限公司 | 一种(s)‑3‑羟基四氢呋喃的制备方法 |
JP2019099571A (ja) * | 2017-11-29 | 2019-06-24 | 中外製薬株式会社 | Glp−1受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物 |
-
2019
- 2019-09-10 CN CN201910850662.0A patent/CN110618208A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5234950A (en) * | 1988-12-23 | 1993-08-10 | Imperial Chemical Industries Plc | Tetrahydrofuran derivatives |
US5928515A (en) * | 1997-12-12 | 1999-07-27 | Uop Llc | Adsorptive separation of 3-hydroxytetrahydrofuran enantiomers |
WO2007081065A1 (en) * | 2006-01-10 | 2007-07-19 | Sk Holdings Co., Ltd. | Method for preparing 3-hydroxytetrahydrofuran using cyclodehydration |
CN106957287A (zh) * | 2016-01-12 | 2017-07-18 | 杭州述康生物技术有限公司 | 一种药物中间体(s)-3-羟基四氢呋喃的制备方法 |
JP2019099571A (ja) * | 2017-11-29 | 2019-06-24 | 中外製薬株式会社 | Glp−1受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物 |
CN107935971A (zh) * | 2017-12-28 | 2018-04-20 | 山东铂源药业有限公司 | 一种(s)‑3‑羟基四氢呋喃的制备方法 |
Non-Patent Citations (4)
Title |
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KEWLEY, ADAM 等: "Porous Organic Cages for Gas Chromatography Separations", 《CHEMISTRY OF MATERIALS》 * |
LUO, YANG 等: "Understanding and Measurement for the Binding Energy of Hydrogen bonds of Biomass-Derived Hydroxyl Compounds", 《JOURNAL OF PHYSICAL CHEMISTRY A》 * |
朱升 等: "(S)-(+)-3-羟基四氢呋喃的合成工艺改进", 《合成化学》 * |
陈凯 等: "2-己基-4-乙酰氧基四氢呋喃顺反异构体的制备", 《精细化工》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112630313A (zh) * | 2020-11-06 | 2021-04-09 | 天地恒一制药股份有限公司 | 一种(s)-3-羟基四氢呋喃对映异构体的高效液相拆分方法 |
CN113092629A (zh) * | 2021-04-14 | 2021-07-09 | 合肥利夫生物科技有限公司 | 一种s-(+)-3-羟基四氢呋喃的纯化和异构体检测方法 |
CN114354801A (zh) * | 2021-12-31 | 2022-04-15 | 山东大学 | (R)-3-Boc-氨基哌啶中三种氨基吡啶异构体含量的分析方法 |
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Effective date of registration: 20210927 Address after: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant after: Dijia Pharmaceutical Group Co.,Ltd. Applicant after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Address before: 266440 No.268, Tianrun Road, Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant before: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. Applicant before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Effective date of registration: 20210927 Address after: 264205 268 Tianrun Road, Wendeng economic and Technological Development Zone, Weihai, Shandong Applicant after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Applicant before: Dijia Pharmaceutical Group Co.,Ltd. Applicant before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. |
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Application publication date: 20191227 |