CN110446790B - 使用外来体rna和无细胞dna检测血浆中的突变的方法和组合物 - Google Patents
使用外来体rna和无细胞dna检测血浆中的突变的方法和组合物 Download PDFInfo
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662428059P | 2016-11-30 | 2016-11-30 | |
| US62/428059 | 2016-11-30 | ||
| PCT/US2017/062370 WO2018102162A1 (en) | 2016-11-30 | 2017-11-17 | Methods and compositions to detect mutations in plasma using exosomal rna and cell free dna from non-small cell lung cancer patients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110446790A CN110446790A (zh) | 2019-11-12 |
| CN110446790B true CN110446790B (zh) | 2023-03-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780084970.6A Active CN110446790B (zh) | 2016-11-30 | 2017-11-17 | 使用外来体rna和无细胞dna检测血浆中的突变的方法和组合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11427864B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3548635B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7280823B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN110446790B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017366813B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3044056A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018102162A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (45)
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| WO2018102162A1 (en) | 2016-11-30 | 2018-06-07 | Exosome Diagnostics, Inc. | Methods and compositions to detect mutations in plasma using exosomal rna and cell free dna from non-small cell lung cancer patients |
| WO2019099629A1 (en) * | 2017-11-17 | 2019-05-23 | Gen-Probe Incorporated | COMPOSITIONS AND METHODS FOR DETECTING C1orf43 NUCLEIC ACID |
| CN108707671A (zh) * | 2018-06-12 | 2018-10-26 | 上海浦美生物医药科技有限公司 | 一种用于血液egfr c797s突变检测的引物探针组合物和试剂盒 |
| CN109207595A (zh) * | 2018-10-07 | 2019-01-15 | 浙江数问生物技术有限公司 | 一种人egfr基因t790m突变检测试剂盒及其检测方法 |
| US20220155304A1 (en) * | 2019-03-01 | 2022-05-19 | Mercy Bioanalytics, Inc. | Systems, compositions, and methods for target entity detection |
| CN110749734A (zh) * | 2019-12-06 | 2020-02-04 | 四川大学华西医院 | Gtf2i自身抗体检测试剂在制备肺癌筛查试剂盒中的用途 |
| CN111733158B (zh) * | 2020-02-11 | 2022-09-06 | 昆明医科大学 | 一种抑制hsa_circ_0003599表达的siRNA及其应用 |
| CN111500640B (zh) * | 2020-04-17 | 2021-09-10 | 四川省人民医院 | Rp疾病模型的构建方法以及培育方法 |
| CN111748624B (zh) * | 2020-06-08 | 2022-11-04 | 郑州大学第一附属医院 | 用于预测肝癌是否复发的生物标志物 |
| CN111676290B (zh) * | 2020-07-02 | 2021-03-02 | 王伟佳 | 一种急性髓系白血病诱导分化治疗耐药的分子标志物及其应用 |
| CN111690752A (zh) * | 2020-07-16 | 2020-09-22 | 重庆浦洛通基因医学研究院有限公司 | 一种检测人类egfr基因突变的试剂盒及其方法 |
| CN112410335B (zh) * | 2020-11-03 | 2022-10-04 | 安徽大学 | 一种阻止lactb2表达来抑制非小细胞肺癌增殖生长的应用 |
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| WO2014193999A2 (en) * | 2013-05-28 | 2014-12-04 | Caris Science, Inc. | Biomarker methods and compositions |
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2017
- 2017-11-17 WO PCT/US2017/062370 patent/WO2018102162A1/en not_active Ceased
- 2017-11-17 AU AU2017366813A patent/AU2017366813B2/en active Active
- 2017-11-17 EP EP17817952.9A patent/EP3548635B1/en active Active
- 2017-11-17 US US16/463,820 patent/US11427864B2/en active Active
- 2017-11-17 CN CN201780084970.6A patent/CN110446790B/zh active Active
- 2017-11-17 JP JP2019528833A patent/JP7280823B2/ja active Active
- 2017-11-17 CA CA3044056A patent/CA3044056A1/en active Pending
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| WO2000071562A1 (en) * | 1999-05-24 | 2000-11-30 | The Public Health Research Institute Of The City Of New York, Inc. | High specificity primers, amplification methods and kits |
| US6812023B1 (en) * | 2000-04-27 | 2004-11-02 | Anosys, Inc. | Methods of producing membrane vesicles |
| CN101627121A (zh) * | 2006-12-08 | 2010-01-13 | 奥斯瑞根公司 | 作为治疗干预的靶标的miRNA调控基因和路径 |
| WO2014193999A2 (en) * | 2013-05-28 | 2014-12-04 | Caris Science, Inc. | Biomarker methods and compositions |
Also Published As
| Publication number | Publication date |
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| AU2017366813B2 (en) | 2023-04-20 |
| EP3548635B1 (en) | 2021-04-28 |
| EP3548635A1 (en) | 2019-10-09 |
| JP2019536456A (ja) | 2019-12-19 |
| CA3044056A1 (en) | 2018-06-07 |
| CN110446790A (zh) | 2019-11-12 |
| JP7280823B2 (ja) | 2023-05-24 |
| WO2018102162A1 (en) | 2018-06-07 |
| AU2017366813A1 (en) | 2019-06-13 |
| US20190376128A1 (en) | 2019-12-12 |
| US11427864B2 (en) | 2022-08-30 |
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