CN110403871A - It is a kind of to have effects that anti-blue light, the composition repaired and the preparation method and application thereof - Google Patents
It is a kind of to have effects that anti-blue light, the composition repaired and the preparation method and application thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
Have effects that anti-blue light, the composition repaired and the preparation method and application thereof the invention discloses a kind of.Described has effects that anti-blue light, the composition repaired comprise the following components in parts by weight: 1~5 part of Troxerutin, 20~45 parts of Gotu Kola P.E, 20~50 parts of spikemoss extract.The stoste containing above-mentioned anti-blue light, the composition for repairing effect that the present invention also provides a kind of.Tests prove that, anti- blue light remediation composition of the invention can effectively resist damage of the blue light to Skin Cell, the phenomenon that improving pachylosis, impaired Skin Cell can also be repaired, reach delay skin aging, reduce the pigmented effect of skin, three kinds of ingredients in composition have significant anti-blue light, repair synergistic effect, and property is mild, highly-safe, will not cause skin irritatin.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to it is a kind of have effects that anti-blue light, repair composition and its
Preparation method and application.
Background technique
With the rapid development of modern economy, the improvement of people's living standards has risen to essence from simple material life
The skin ageing problem of the life of refreshing level, people is also increasingly taken seriously, and skin aging refers under symbol wrinkle, skin
It hangs down, the cosmetic variation of pigementation.Wrinkle and sagging formation be by physiological ageing and light aging it is compound in the form of carry out.
The main reason for skin photoage is ultraviolet light, but recently not only to ultraviolet light, in the mechanical, electrical view of opponent, various headlamps etc.
The worry of the blue light of generation is also increasing.Modern life is under biometrics environment, the time of exposure under blue light is increasingly longer.
Blue light is the visible rays of the series of blue present in 380~500nm wavelength, is present in sunray, computer display screen,
Also more release in the artificial illumination such as TV, LED light, blue light is higher to skin permeability, for a long time when exposure, meeting damaging cells
DNA slows down the resume speed of skin barrier, becomes the immediate cause of skin aging, causes chloasma, melanin pigmentation, simultaneously
Damage eye health.It is stronger than ultraviolet light that luminous energy is transmitted to the ability on skin by blue light, becomes the reason of active oxygen generates.At present
The effect of common skin-protection product defence blue light is not ideal enough.
Summary of the invention
The defect that the purpose of the invention is to make up existing anti-blue light, repair product, it is simple to provide a kind of prescription, holds
Easily preparation, safety do not stimulate, and anti-blue light, reparation extraordinary composition of effect and the preparation method and application thereof.
The present invention is achieved by the following technical programs:
A kind of composition for having effects that anti-blue light, repairing, comprises the following components in parts by weight:
1~5 part of Troxerutin
20~45 parts of Gotu Kola P.E
20~50 parts of spikemoss extract.
It is preferred that the Troxerutin is prepared using following methods:
(1) the sophora flower seed dried is crushed, is by weight 1:1~2 by smashed sophora flower seed and 95% full gear alcohol
Ratio add in heating and stirring pot, 4~6h of stirring is heated to reflux at 95~100 DEG C, after the completion of extraction, is cooled to 55~65
DEG C, it is filtered to remove sophora flower seed, takes filtrate, filtrate is relay into heating kettle, 85~90 DEG C is warming up to, filters while hot, use PP
Cotton filter core filters, and takes filtrate, spare；
(2) filtrate that step (1) obtains is placed in the heating kettle with vacuum, is vacuumized, heating is opened, at 75~80 DEG C
Under steam full gear alcohol, steam always until there is no alcohol into heating kettle, that is, complete distillation, take crystalline solid in pot, drying to get
To Troxerutin.
It is preferred that the Gotu Kola P.E is prepared using following methods:
(1) centella dried is crushed, is by weight 1:2~3 by smashed centella and 95% full gear alcohol
Ratio add to and be heated to reflux in pot, 2~3h of boiling is heated to reflux at 95~100 DEG C, filters, takes after being cooled to 45~55 DEG C
Filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 60~65 DEG C, to be filtered
When liquid is evaporated to remaining 1/5th volume, the dipropylene glycol of 1.5~2.5 times of centella weight is added, stirs evenly, is mixed
Close liquid；
(3) mixed liquor that step (2) obtains is transferred to rotary evaporator in batches, then is vacuumized, it will at 58~60 DEG C
Remaining full gear alcohol removes, and obtains Gotu Kola P.E.
It is preferred that the spikemoss extract is prepared using following methods:
(1) Selaginella tamariscina dried is crushed, is by weight the ratio of 1:2~3:1 by smashed Selaginella tamariscina, butanediol and water
It adds to and is heated to reflux in pot, 2~3h of boiling is heated to reflux at 95~100 DEG C, filtered after being cooled to 45~55 DEG C, take filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 80~85 DEG C, to be filtered
When liquid is evaporated to remaining one third volume, the butanediol with step (1) equivalent is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is added to be heated to reflux in pot and is reheated, then filtered while hot, take filtrate
Obtain spikemoss extract.
The present invention also provides described to have effects that anti-blue light, the composition repaired have anti-blue light, reparation function in preparation
The skin care item of effect or the application in cosmetics.
It is preferred that the skin care item or cosmetics include the products such as aqua, lotion or white class.
Have effects that anti-blue light, the anti-blue light reparation for the composition repaired are former containing above-mentioned the present invention also provides a kind of
Liquid.
It is preferred that the anti-blue light repairs stoste, the component including following mass percent meter:
It is further preferred that the anti-blue light repairs stoste, the component including following mass percent meter:
It is preferred that the polyalcohol in 1,3-BDO, glycerol, 1,3-PD, pentanediol, dipropylene glycol extremely
Few one kind.
The present invention also provides a kind of methods for preparing above-mentioned anti-blue light and repairing stoste, comprising the following steps:
(1) water, polyalcohol, hyaluronic acid, xanthan gum, parahydroxyacet-ophenone, hexylene glycol are added in water phase pot, are heated to
80~84 DEG C, insulated and stirred is uniformly dissolved；
(2) when being cooled to 40~45 DEG C, anti-blue light remediation composition, inositol is added, stirs evenly and is repaired to get to anti-blue light
Restore liquid.
Compared with prior art, the invention has the following advantages:
(1) Troxerutin has good absorption blue light, inhibits skin blood capillary in anti-blue light remediation composition of the invention
The increase of pipe permeability prevents thrombosis, increases oxygen content of blood, improves the effect of blood vessel microcirculation, Gotu Kola P.E
Have the function of the generation for improving and repairing skin barrier, reducing inflammatory mediator (IL-1, MMP-1), people can also be promoted at fibre
The synthesis of the proliferation and human collagen protein I type and 3 types of cell is tieed up to have the function that skin ultrastructure, spikemoss extract tool
There is free radical in potent removing skin, alleviate skin aging, repair impaired skin tissue, promotes wound healing and other effects,
Triple combination gets up to apply, and not only compensates for the obvious shortcoming that each extract has a single function, but also there is complementary promote to imitate
Fruit, the anti-blue light of more obvious raising is anti-oxidant, removes free radical and the effect that soothes the skin, so as to effectively alleviate because
The problems such as skin aging caused by blue light, pigmentation, can also repair impaired skin well, reach alleviation skin aging
Powerful effect.
(2) product of the invention will not generate phenomena such as allergy, stimulation to user, and use is safe；Product of the invention
There is significant effect on the effect of anti-blue light, repairing damaged skin cell, keep skin youth vigor.
Specific embodiment
The following examples are further illustrations of the invention, rather than limiting the invention.Match in following embodiments
The component of side is unless otherwise noted conventional commercial product.
Embodiment 1
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
Preparation step:
(1) water, glycerol, hyaluronic acid, xanthan gum, parahydroxyacet-ophenone, hexylene glycol are added in water phase pot, are heated to 80
DEG C, insulated and stirred is uniformly dissolved；
(2) when being cooled to 40 DEG C, Troxerutin, Gotu Kola P.E, spikemoss extract, inositol is added, stirs evenly, i.e.,
It obtains anti-blue light and repairs stoste.
Wherein, Troxerutin, Gotu Kola P.E, spikemoss extract be prepared as it is as follows:
1, the preparation of Troxerutin:
(1) the sophora flower seed dried is crushed, is by weight 1:1.5's by smashed sophora flower seed and 95% full gear alcohol
Ratio adds in heating and stirring pot, and stirring 4h is heated to reflux at 98 DEG C, after the completion of extraction, 60 DEG C are cooled to, with the filter of 200 mesh
Cloth filters while hot removes sophora flower seed, takes filtrate, filtrate is relay into heating kettle, and unlatching is heated to 85 DEG C, while hot mistake
Filter is filtered with the PP cotton filter element of 0.1mm, takes filtrate, spare；
(2) filtrate that step (1) obtains is placed in the heating kettle with vacuum, is vacuumized, opened heating, steamed at 78 DEG C
Full gear alcohol out steams always until not having alcohol into heating kettle, that is, completes distillation, takes crystalline solid in pot, and drying is bent to get arriving
Gram rutin.
2, the preparation of Gotu Kola P.E:
(1) centella dried is crushed, is by weight the ratio of 1:2 by smashed centella and 95% full gear alcohol
Example adds to stainless steel and is heated to reflux in pot, and boiling 2h is heated to reflux at 98 DEG C, clean with 200 purposes after being then cooled to 50 DEG C
Filtered through gauze takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 62 DEG C, steams to filtrate
When being sent to remaining 1/5th volume, the dipropylene glycol of 2 times of centella weight is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is transferred to rotary evaporator in batches, then is vacuumized, it will be remaining at 58 DEG C
Full gear alcohol remove, obtain Gotu Kola P.E.
3, the preparation of spikemoss extract:
(1) Selaginella tamariscina dried is crushed, the ratio that smashed Selaginella tamariscina, butanediol and water are 1:2:1 by weight is added
It is heated to reflux in pot to stainless steel, boiling 2h is heated to reflux at 98 DEG C, with the clean gauze of 200 purposes after being then cooled to 50 DEG C
Filtering, takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 80 DEG C, steams to filtrate
When being sent to remaining one third volume, the butanediol with step (1) equivalent is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is added to be heated to reflux in pot and is reheated, then filtered while hot, take filtrate
Obtain spikemoss extract.
Embodiment 2
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
Preparation step:
(1) water, glycerol, hyaluronic acid, xanthan gum, parahydroxyacet-ophenone, hexylene glycol are added in water phase pot, are heated to 84
DEG C, insulated and stirred is uniformly dissolved；
(2) when being cooled to 45 DEG C, be added Troxerutin, Gotu Kola P.E, spikemoss extract, inositol, stir evenly,
It obtains anti-blue light and repairs stoste.
Wherein, Troxerutin, Gotu Kola P.E, spikemoss extract be prepared as it is as follows:
1, the preparation of Troxerutin:
(1) the sophora flower seed dried is crushed, is by weight the ratio of 1:2 by smashed sophora flower seed and 95% full gear alcohol
Example adds in heating and stirring pot, and stirring 4h is heated to reflux at 100 DEG C, after the completion of extraction, 55 DEG C are cooled to, with the filter of 200 mesh
Cloth filters while hot removes sophora flower seed, takes filtrate, filtrate is relay into heating kettle, and unlatching is heated to 90 DEG C, while hot mistake
Filter is filtered with the PP cotton filter element of 0.1mm, takes filtrate, spare；
(2) filtrate that step (1) obtains is placed in the heating kettle with vacuum, is vacuumized, opened heating, steamed at 75 DEG C
Full gear alcohol out steams always until not having alcohol into heating kettle, that is, completes distillation, takes crystalline solid in pot, and drying is bent to get arriving
Gram rutin.
2, the preparation of Gotu Kola P.E:
(1) centella dried is crushed, is by weight the ratio of 1:3 by smashed centella and 95% full gear alcohol
Example adds to stainless steel and is heated to reflux in pot, and boiling 3h is heated to reflux at 95 DEG C, clean with 200 purposes after being then cooled to 55 DEG C
Filtered through gauze takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 65 DEG C, steams to filtrate
When being sent to remaining 1/5th volume, the dipropylene glycol of 1.5 times of centella weight is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is transferred to rotary evaporator in batches, then is vacuumized, it will be remaining at 60 DEG C
Full gear alcohol remove, obtain Gotu Kola P.E.
3, the preparation of spikemoss extract:
(1) Selaginella tamariscina dried is crushed, the ratio that smashed Selaginella tamariscina, butanediol and water are 1:3:1 by weight is added
It is heated to reflux in pot to stainless steel, boiling 3h is heated to reflux at 95 DEG C, with the clean gauze of 200 purposes after being then cooled to 45 DEG C
Filtering, takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 85 DEG C, steams to filtrate
When being sent to remaining one third volume, the butanediol with step (1) equivalent is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is added to be heated to reflux in pot and is reheated, then filtered while hot, take filtrate
Obtain spikemoss extract.
Embodiment 3
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
Preparation step:
(1) water, glycerol, hyaluronic acid, xanthan gum, parahydroxyacet-ophenone, hexylene glycol are added in water phase pot, are heated to 82
DEG C, insulated and stirred is uniformly dissolved；
(2) when being cooled to 42 DEG C, be added Troxerutin, Gotu Kola P.E, spikemoss extract, inositol, stir evenly,
It obtains anti-blue light and repairs stoste.
Wherein, Troxerutin, Gotu Kola P.E, spikemoss extract be prepared as it is as follows:
1, the preparation of Troxerutin:
(1) the sophora flower seed dried is crushed, is by weight the ratio of 1:1 by smashed sophora flower seed and 95% full gear alcohol
Example adds in heating and stirring pot, and stirring 6h is heated to reflux at 95 DEG C, after the completion of extraction, 65 DEG C are cooled to, with the filter cloth of 200 mesh
Sophora flower seed is removed in filtering while hot, takes filtrate, filtrate is relay into heating kettle, and unlatching is heated to 85 DEG C, filters while hot,
It is filtered with the PP cotton filter element of 0.1mm, takes filtrate, it is spare；
(2) filtrate that step (1) obtains is placed in the heating kettle with vacuum, is vacuumized, opened heating, steamed at 80 DEG C
Full gear alcohol out steams always until not having alcohol into heating kettle, that is, completes distillation, takes crystalline solid in pot, and drying is bent to get arriving
Gram rutin.
2, the preparation of Gotu Kola P.E:
(1) centella dried is crushed, is by weight the ratio of 1:2 by smashed centella and 95% full gear alcohol
Example adds to stainless steel and is heated to reflux in pot, and boiling 2h is heated to reflux at 100 DEG C, dry with 200 purposes after being then cooled to 45 DEG C
Net filtered through gauze, takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 60 DEG C, steams to filtrate
When being sent to remaining 1/5th volume, the dipropylene glycol of 2.5 times of centella weight is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is transferred to rotary evaporator in batches, then is vacuumized, it will be remaining at 58 DEG C
Full gear alcohol remove, obtain Gotu Kola P.E.
3, the preparation of spikemoss extract:
(1) Selaginella tamariscina dried is crushed, the ratio that smashed Selaginella tamariscina, butanediol and water are 1:2:1 by weight is added
It is heated to reflux in pot to stainless steel, boiling 2h is heated to reflux at 100 DEG C, with the clean yarn of 200 purposes after being then cooled to 55 DEG C
Cloth filtering, takes filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 85 DEG C, steams to filtrate
When being sent to remaining one third volume, the butanediol with step (1) equivalent is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is added to be heated to reflux in pot and is reheated, then filtered while hot, take filtrate
Obtain spikemoss extract.
Comparative example 1
Comparative example 1 is a blank control, the stoste without anti-blue light remediation composition comprising following mass percent
The component of meter:
Preparation method reference implementation example 1.
Comparative example 2
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
The anti-blue light of comparative example 2 repairs stoste compared with embodiment 1, and difference is, anti-blue light remediation composition is containing only Qu Ke
Rutin, preparation method reference implementation example 1.
Comparative example 3
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
The anti-blue light of comparative example 3 repairs stoste compared with embodiment 1, and difference is, anti-blue light remediation composition is containing only accumulated snow
Careless extract, preparation method reference implementation example 1.
Comparative example 4
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
The anti-blue light of comparative example 4 repairs stoste compared with embodiment 1, and difference is, anti-blue light remediation composition is containing only Selaginella tamariscina
Extract, preparation method reference implementation example 1.
Comparative example 5
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
The anti-blue light of comparative example 4 repairs stoste compared with embodiment 1, and difference is, anti-blue light remediation composition is containing only Qu Ke
Rutin and spikemoss extract, preparation method reference implementation example 1.
Embodiment 4
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
Preparation step reference implementation example 1.
Embodiment 5
A kind of anti-blue light reparation stoste, the component including following mass percent meter:
Preparation step reference implementation example 1.
One, physical and chemical testing
Stoste is repaired to anti-blue light made from embodiment 1-3 and comparative example 1-5 respectively and carries out physical and chemical testing, as a result as follows:
1, appearance: the stoste of comparative example 1 is colorless and transparent thick liquid, the yellowish clear viscous liquids of remaining stoste.
2, pH value: the stoste pH range of embodiment 1-3 and comparative example 1-5 is all between 5.5-7.5.
3, heat-resistant stability investigates (48 DEG C × 72h): all stostes of heat-resistant stability are qualified.
4, resist cold study on the stability (- 15 DEG C × 72h): cold-resistant all stostes of stability are qualified.
Two, safety and both effectiveness detection
(1) human safety patch test:
Experimental procedure: it chooses area and is no more than 50mm2, the qualified patch utensil of depth about 1mm, in 30 voluntary testers
Back do patch test, it is respectively that bulk samples made from embodiment 1-3, comparative example 1-5 and blank control sample are (pure
Water) it is placed on patch utensil in order, the sample of embodiment 1-3 and comparative example 1-5 choose 0.02mL, and control wells are placed pure
Water as blank control sample, test by the back for the tester for being then attached to each with low sensitization adhesive tape, is gently pressed with palm
It is allowed to uniformly be pasted on skin, continue for 24 hours.
Experimental result: after test for 24 hours, 30min (after band impression disappears) after the patch equipment at subject back, observation are removed
The reaction that the skin of back of subject does not have an example the phenomenon that red, shouting pain or doubtful erythema occur illustrates the present invention containing anti-
The stoste of blue light remediation composition be it is safe, without any adverse reaction phenomenon occur.
(2) anti-blue light efficacy assessments test:
Test sample: bulk samples made from embodiment 1-3 and comparative example 1-5, the incubator for having blue light source, angle containing people
Change the culture medium of cell, opsin (opsin-3) fluorescent marker, optical microscopy.
Experimental procedure: 8 culture mediums containing human keratinocyte are chosen, number is numbered with respectively, then sequentially adds identical
Bulk samples made from the embodiment 1-3 and comparative example 1-5 of amount add same amount of opsin (opsin-3) fluorized marking
Object is finally placed in the incubator of blue light source and cultivates for 24 hours, take out culture medium afterwards for 24 hours, is placed on microscope and observes fluorescence
Density in the medium.
Experimental result: the culture medium fluorescence intensity of the bulk samples of embodiment 1-3 successively weakens, and the fluorescence of embodiment 1 is close
Degree is maximum, accounts for the 93% of culture medium area；The culture medium fluorescence intensity of embodiment 2 is 73%；The culture medium fluorescence of embodiment 3 is close
Degree is 65%；The fluorescence intensity range of comparative example 1 is minimum, absolutely not extent of fluorescence, fluorescence intensity 0%；The training of comparative example 2
Supporting base fluorescence intensity is 52%；The culture medium fluorescence intensity of comparative example 3 and comparative example 4 very close to, about 2%, fluorescence intensity is very
Weak, the culture medium fluorescence intensity of comparative example 5 is 59%.Since human keratinocyte can secrete a kind of albumen opsin (opsin-
3) it, can reduce or even do not secrete under the irradiation of blue light, so will if the sample not anti-blue light added the effect of
Reduce opsin (opsin-3) even without can be become totally visible with fluorized marking method.By above-mentioned result it is found that reality
The anti-blue light effect of bulk samples for applying a 1-3 is substantially better than the bulk samples of comparative example 1-5, and in the sample of embodiment 1-3, with
The reduction of Troxerutin concentration, the effect of anti-blue light increasingly weaker trend, therefore anti-indigo plant provided by the invention is also presented
Troxerutin, Gotu Kola P.E, spikemoss extract triple combination application, there is the anti-blue light of collaboration to repair in light remediation composition
Multiple effect.
(3) both effectiveness test is repaired in lactic acid shouting pain:
Test sample: bulk samples made from embodiment 1-3 and comparative example 1-5,10%v/v lactic acid solution.
Experimental subjects: the volunteer of 8 30-45 years old skin healths is chosen.
Experimental procedure: choosing 8 volunteers, coats the stimulation of 10% lactic acid solution in everyone arm side respectively, draws
It plays arm skin and the symptoms such as red, shouting pain occurs, then with the sample of embodiment 1-3 and comparative example 1-5 go to repair respectively stimulated
Skin, corresponding volunteer 1 using embodiment 1 bulk samples, corresponding volunteer 2 using embodiment 2 bulk samples,
Corresponding volunteer 3 using embodiment 3 bulk samples, corresponding volunteer 4 using comparative example 1 bulk samples, corresponding
Volunteer 5 uses the bulk samples of comparative example 3, corresponding volunteer 7 using the bulk samples of comparative example 2, corresponding volunteer 6
The bulk samples of comparative example 5 are used using the bulk samples of comparative example 4, corresponding volunteer 8.
Record the time: the case where recording the skin repair of arm skin 1h, 3h, 7h, 12h respectively.
Experimental result:
1 lactic acid shouting pain repairing effect testing result of table
As shown in Table 1, the bulk samples of embodiment 1-3 with anti-blue light remediation composition dosage reduce, to skin
Repairing effect reduce, it is best with repairing effect of the bulk samples of embodiment 1 to skin.Comparative example 1 is free of anti-blue light reparation
Composition does not have effect to skin repair, and comparative example 2 contains only Troxerutin, comparative example 3-4 poor to the repairing effect of skin
Gotu Kola P.E and spikemoss extract are contained only respectively, skin repair effect is reduced, and comparative example 5 contains Troxerutin and Selaginella tamariscina
Extract is better than comparative example 3-4 to the repairing effect of skin, but still is weaker than embodiment 3, it can be seen that anti-indigo plant of the invention
Troxerutin, Gotu Kola P.E, spikemoss extract three, which cooperate with, in light remediation composition plays good skin repair and resists
The effect of blue light.
In conclusion the anti-blue light containing anti-blue light remediation composition, reparation stoste are safety, and low stimulation, Er Qiejing
The phenomenon that being often used, capable of effectively resisting damage of the blue light to Skin Cell, improve pachylosis, moreover it is possible to repair impaired skin
Cell reaches delay skin aging, reduces the pigmented effect of skin.
The above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair
Limitation of the invention, protection scope of the present invention should be defined by the scope defined by the claims..For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, several improvements and modifications can also be made, these change
It also should be regarded as protection scope of the present invention into retouching.
Claims (10)
1. a kind of composition for having effects that anti-blue light, repairing, which is characterized in that comprise the following components in parts by weight:
1~5 part of Troxerutin
20~45 parts of Gotu Kola P.E
20~50 parts of spikemoss extract.
2. the composition according to claim 1 for having effects that anti-blue light, repairing, which is characterized in that the Qu Kelu
Fourth is prepared using following methods:
(1) the sophora flower seed dried is crushed, is by weight the ratio of 1:1~2 by smashed sophora flower seed and 95% full gear alcohol
Example adds in heating and stirring pot, and 4~6h of stirring is heated to reflux at 95~100 DEG C, after the completion of extraction, is cooled to 55~65 DEG C,
It is filtered to remove sophora flower seed, takes filtrate, filtrate is relay into heating kettle, 85~90 DEG C is warming up to, filters while hot, is filtered with PP cotton
Core filters, and takes filtrate, spare；
(2) filtrate that step (1) obtains is placed in the heating kettle with vacuum, is vacuumized, opened heating, steamed at 75~80 DEG C
Full gear alcohol out steams always until not having alcohol into heating kettle, that is, completes distillation, takes crystalline solid in pot, and drying is bent to get arriving
Gram rutin.
3. the composition according to claim 1 for having effects that anti-blue light, repairing, which is characterized in that the centella
Extract is prepared using following methods:
(1) centella dried is crushed, is by weight the ratio of 1:2~3 by smashed centella and 95% full gear alcohol
Example, which adds to, to be heated to reflux in pot, and 2~3h of boiling is heated to reflux at 95~100 DEG C, is filtered after being cooled to 45~55 DEG C, filter is taken
Liquid；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 60~65 DEG C, steams to filtrate
When being sent to remaining 1/5th volume, the dipropylene glycol of 1.5~2.5 times of centella weight is added, stirs evenly, is mixed
Liquid；
(3) mixed liquor that step (2) obtains is transferred to rotary evaporator in batches, then is vacuumized, it will be remaining at 58~60 DEG C
Full gear alcohol remove, obtain Gotu Kola P.E.
4. the composition according to claim 1 for having effects that anti-blue light, repairing, which is characterized in that the Selaginella tamariscina mentions
Object is taken to be prepared using following methods:
(1) Selaginella tamariscina dried is crushed, the ratio that smashed Selaginella tamariscina, butanediol and water are 1:2~3:1 by weight is added to
It is heated to reflux in pot, 2~3h of boiling is heated to reflux at 95~100 DEG C, filtered after being cooled to 45~55 DEG C, take filtrate；
(2) the filtrate dislocation for obtaining step (1) vacuumizes in rotary evaporator, distills at 80~85 DEG C, steams to filtrate
When being sent to remaining one third volume, the butanediol with step (1) equivalent is added, stirs evenly, obtains mixed liquor；
(3) mixed liquor that step (2) obtains is added to be heated to reflux in pot and is reheated, then filtered while hot, filtrate is taken to make
Obtain spikemoss extract.
5. having effects that anti-blue light, the composition repaired have anti-blue light, reparation function in preparation described in claim 1-4 is any
The skin care item of effect or the application in cosmetics.
6. a kind of anti-blue light repairs stoste, which is characterized in that described there is anti-blue light, reparation containing claim 1-4 is any
The composition of effect.
7. anti-blue light according to claim 6 repairs stoste, which is characterized in that the group including following mass percent meter
Point:
8. anti-blue light according to claim 7 repairs stoste, which is characterized in that the group including following mass percent meter
Point:
9. anti-blue light according to claim 7 or 8 repairs stoste, which is characterized in that the polyalcohol is selected from 1,3- fourth
At least one of glycol, glycerol, 1,3- propylene glycol, pentanediol, dipropylene glycol.
10. a kind of prepare the method that anti-blue light repairs stoste described in claim 7 or 8, which comprises the following steps:
(1) water, polyalcohol, hyaluronic acid, xanthan gum, parahydroxyacet-ophenone, hexylene glycol are added in water phase pot, it is heated to 80~
84 DEG C, insulated and stirred is uniformly dissolved；
(2) when being cooled to 40~45 DEG C, anti-blue light remediation composition, inositol is added, stirs evenly former to get being repaired to anti-blue light
Liquid.
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