CN110403850A - A kind of polysaccharide whitening solid-state facial mask and the preparation method and application thereof - Google Patents
A kind of polysaccharide whitening solid-state facial mask and the preparation method and application thereof Download PDFInfo
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- CN110403850A CN110403850A CN201910762692.6A CN201910762692A CN110403850A CN 110403850 A CN110403850 A CN 110403850A CN 201910762692 A CN201910762692 A CN 201910762692A CN 110403850 A CN110403850 A CN 110403850A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of polysaccharide whitening solid-state facial masks and the preparation method and application thereof.Method includes the following steps: (1) prepares facial mask liquid: each raw material of facial mask liquid being mixed evenly, homogeneous is then carried out, obtains facial mask liquid；Wherein, facial mask liquid includes following component as mass fraction: 5~50 parts of polysaccharide compositions, 0~20 part of Sodium Hyaluronate, 0~5 part of pearl powder and 20~95 parts of water；The polysaccharide composition includes bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide；(2) it prepares polysaccharide whitening solid-state facial mask: cellulose face paper being impregnated into facial mask liquid, is then dried in vacuo, transparence is presented in drying to facial mask liquid, then sterilizes, and obtains polysaccharide whitening solid-state facial mask.Solid-state facial mask moistening effect prepared by the present invention is good, and energy wound healing has good tyrosinase inhibition and inoxidizability, positive adjustment effect is played to skin microbial state.
Description
Technical field
The present invention relates to technical field of skin care, and in particular to a kind of polysaccharide whitening solid-state facial mask and preparation method thereof with answer
With.
Background technique
With the raising of people's quality of the life and the pursuit to overall appearance promotion, cosmetics and skincare product is increasingly by blueness
It looks at.Facial mask has become mostly important in skin care item one because its nutritional ingredient height, skin effect are significant, easy to use
Part.Facial mask is covered on the of short duration time of face using Essence, is temporarily isolating extraneous air and pollution, improves skin temperature
Degree, the pore expansion of skin, promotes sweat gland secretion and metabolism, increase the oxygen content of skin, be conducive to skin exclusion table
The product of chrotoplast metabolism and the oil substances of accumulation, the nutriment in facial mask penetrate into the cuticula of epidermis, skin
Become soft, skin is naturally bright flexible.
Common facial mask is usually all manufactured with wet-format, by nonwoven fabric or elasticity face paper be immersed in beauty at
Point Essence in, when use, tears the sealed package of facial mask, can directly take out and be stained with the facial mask of Essence and spread on face.But
In wet type facial mask, since facial mask essence is rich in nutritional ingredient, for long-time storage and retain physiological activity, in Essence
Adding a large amount of preservatives, preservative and surfactant has menace to skin health.While product is in process of production
Remaining microorganism also will affect the health of skin, while some unstable but high bioactivity raw material can decline in facial mask
Subtract, is unfavorable for saving and playing its biological effect.
Solid-state facial mask is novel category in facial treatment mask patch, few with preservative, easy to use and approve by consumer, energy
Active material is set to be uniformly distributed in the surface of facial mask cloth, the common practice of current solid-state facial mask is that facial mask cloth is immersed in essence
In, then by drying or dry, cutting, but the active material being present in Essence easily loses activity, therefore should be avoided
The decomposition of active material in drying course.
Polysaccharide is to pass through glycan made of glucosides key connection as 10 or more monosaccharide, extensive in distributed in nature, is composition
The natural macromolecular substance of higher plant, animal cell membrane and microorganism wall.Studies have found that a variety of polysaccharide are with outstanding
Tyrosinase inhibitory activity and antioxidant activity, be conducive to inhibit dermal melanin generation, have effect significant beauty
White effect.Polysaccharide for understand skin microbial stable state also there is apparent effect, for harmful bacteria growth inhibition and have
The promotion of beneficial bacteria growth all plays good effect.Polysaccharide component is played excellent due to the rheological characteristic of itself in facial mask essence
Good thickener effect, reduces Essence to the irritation of skin.
Based on above-mentioned technical background, exploitation is a to skin health, is conducive to adjust skin Tiny ecosystem, active constituent performance
Good facial mask is saved with the very big market demand.
Summary of the invention
The primary purpose of the present invention is that the shortcomings that overcoming the prior art and deficiency, provide a kind of polysaccharide whitening solid-state facial mask
Preparation method.
Another object of the present invention is to provide the polysaccharide whitening solid-state facial masks that the method is prepared.
A further object of the present invention is to provide the applications of the polysaccharide whitening solid-state facial mask.
The purpose of the invention is achieved by the following technical solution: a kind of preparation method of polysaccharide whitening solid-state facial mask, including
Following steps:
(1) facial mask liquid is prepared
Each raw material of facial mask liquid are mixed evenly, homogeneous is then carried out, obtains facial mask liquid；Wherein, facial mask liquid includes
Component as mass fraction as follows: 5~50 parts of polysaccharide compositions, 0~20 part of Sodium Hyaluronate, 0~5 part of pearl powder and 20~
95 parts of water；The polysaccharide composition includes bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide；
(2) polysaccharide whitening solid-state facial mask is prepared
Cellulose face paper is impregnated into the facial mask liquid that step (1) obtains, is then dried in vacuo, it is dry to facial mask
Transparence is presented in liquid, then sterilizes, and obtains polysaccharide whitening solid-state facial mask.
The condition of stirring described in step (1) are as follows: 100r/min~2500r/min stirs 20~60min；It is preferred that are as follows: 4
DEG C, 600r/min~1000r/min stirs 20~60min.
Homogeneous described in step (1) preferably uses Microfluidizer to carry out homogeneous, condition are as follows: 100~
Homogeneous 2~20 times under 300Mpa；It is preferred that are as follows: homogeneous 10~20 times under 200~300Mpa.
Facial mask liquid described in step (1) preferably includes following component as mass fraction: 20~50 parts of polysaccharide groups
Point, 10~15 parts of Sodium Hyaluronates, 2~5 parts of pearl powders and 30~68 parts of water；More preferably comprising it is following as mass fraction
Component: 20~50 parts of polysaccharide components, 10~15 parts of Sodium Hyaluronates, 2 parts of pearl powders and 38~68 parts of water.
The molecular weight of the Sodium Hyaluronate is 80~2,000,000 dalton, purity >=90%.
The pearl powder is preferably fresh water pearl powder.
Polysaccharide composition described in step (1) is the polysaccharide composition of 1~500mg/ml of concentration；Preferably concentration 10~
The polysaccharide composition of 15mg/ml.
Mass ratio 1:0.01~0.8:0.01 of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (1)~
0.8；Preferably 1:0.1~0.5:0.1~0.5.
Polysaccharide composition described in step (1) is prepared preferably by following method:
By bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide at 4 DEG C, stirred 20 minutes under the conditions of 1000r/min；Then exist
Homogeneous stirs 10 times under 200Mpa, obtains the polysaccharide composition of homogeneous system.
The homogeneous preferably uses Microfluidizer to carry out homogeneous.
The polyoses content of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (1) is >=97%, can be with
The bletilla striata, Poria cocos, Radix Paeoniae Alba are that raw material extracts to obtain.
Bletilla polysaccharide described in step (1), pachymaran and Radix Paeoniae Alba polysaccharide are prepared into preferably by following method
It arrives:
(I) bletilla striata or Poria cocos or Radix Paeoniae Alba are dried and is broken into powder, be sieved, dehydrated alcohol is then added and extracts degreasing, takes out
Filter is repeated 2 times above, filtering, then the filter cake being obtained by filtration is dried in vacuo, the bletilla striata or Poria cocos or Radix Paeoniae Alba after obtaining degreasing；
(II) in the bletilla striata or Poria cocos or Radix Paeoniae Alba after distilled water to be added to degreasing, solid-liquid ratio is 1:30 (g/mL), in 70
It is extracted under~80 DEG C of water bath conditions, filters, be repeated 2 times above, be then combined with filtrate and concentrate it to 1/4 volume, then
Dehydrated alcohol to system volume fraction of ethanol is added and reaches 80%, stands overnight, finally filters, taking precipitate, washing, freezing are dry
It is dry, obtain Thick many candies；
(III) by Thick many candies decoloration, purifying, concentration, freeze-drying, obtain bletilla polysaccharide after purification, pachymaran or
Radix Paeoniae Alba polysaccharide.
Sieving described in step (I) preferably sieves with 100 mesh sieve.
The time of degreasing described in step (I) is preferably 4h.
Vacuum drying described in step (I) is to be dried in vacuo under the conditions of 50 DEG C.
The condition of extraction described in step (II) is preferred are as follows: under 400W ultrasonic wave added, 50 DEG C of water-baths extract 30 minutes
Afterwards, then in 70 DEG C of water-baths it extracts 3 hours.
Filtering described in step (II) preferably uses 4 layer of 200 mesh filter cloth to be filtered.
Concentration described in step (II) is that rotary evaporation in vacuo is concentrated；Preferably vacuum rotating under the conditions of 65 DEG C
Evaporation is concentrated.
Washing described in step (II) preferably uses acetone and ether to be washed.
Decoloration described in step (III) preferably uses active carbon to decolourize；It is realized preferably by following steps:
Thick many candies plus water are redissolved, polysaccharide liquid is obtained；Then active carbon is added, is handled 30~60 minutes under 50 DEG C of water-baths, filters, obtains
Polysaccharide after to decoloration.
The concentration of the polysaccharide liquid is preferably 10mg/mL.
The dosage of the active carbon is the 1%~3% of polysaccharide liquid quality.
Purifying described in step (III) is that molecular cut off is used to be purified for 5000Da bag filter；Preferably adopt
It is that 5000Da bag filter purifies 12h with molecular cut off.
Concentration described in step (III) is to be concentrated into 1/4 volume.
The polyoses content of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (III) after purification be >=
97%.
Cellulose face paper described in step (2) is obtained by raw material, doping cellulose nanometer fibril of plant fiber,
With specific reference to Chinese patent application: application No. is 201810266299.3, a kind of entitled " the ultra-thin face paper of high water conservation highly-flexible
And the preparation method and application thereof " in method (method preferably in embodiment 6), quantification of 10~100g/ is prepared
m2, preferably 60~80g/m2。
The condition of dipping described in step (2) are as follows: impregnated 8~24 hours under 4 DEG C of gnotobasis；It is preferred that are as follows: at 4 DEG C
It is impregnated 18~24 hours under gnotobasis.
Vacuum drying condition described in step (2) are as follows: 40~60 DEG C drying 3~24 hours；It is preferred that are as follows: 50 DEG C of dryings
24 hours.
The preparation method of the polysaccharide whitening solid-state facial mask further includes by polysaccharide whitening solid-state face after step (2)
The step of film is sealed and sterilizes.
Described being sealed into is sealed under vacuum conditions.
The sterilizing is to be sterilized using pasteur's method.
The sterilising conditions of the pasteur's method are as follows: sterilize 24 hours at 70 DEG C.
A kind of polysaccharide whitening solid-state facial mask, is prepared by method described in any of the above embodiments.
Application of the polysaccharide whitening solid-state facial mask in cosmetic field.
The present invention has the following advantages and effects with respect to the prior art:
1, the cellulose face paper that the present invention uses is made by micro-nano fibril for raw material, and micro-nano fibril has specific surface
Product is high, modulus is big, and the feature that adsorption capacity is strong, has micro- peeling effect to skin aging horn cell, by facial mask and essence
Liquid phase combines, and can quickly adsorb the nutriment of Essence and penetrate into skin.
2, the facial mask liquid in the present invention is by bletilla polysaccharide, pachymaran, Radix Paeoniae Alba polysaccharide, Sodium Hyaluronate, pearl powder and water
It is made of component, main functional component is plant origin, and polysaccharide component is because its own is with viscosity, to the low irritant of skin
And the modulability of skin microbial state, active constituent are able to maintain optimal efficacy, have moisturizing after use, moisten, whitening, convergence
Pore and shine skin glosser and other effects.
3, the present invention remaines in the facial mask liquid for being full of polysaccharide component on face paper, and more using the reservation of low temperature drying technology
The physiological activity of saccharic composition reduces the probability of bacteria breed while making it easier to save, do not need addition preservative, ensure and use
The skin health of person；Matched sterile water is poured into container when use, is drawn off after face paper soakage water, spreads on face
Use allows user that can easily use facial mask and keeps clean.
4, solid-state facial mask is made using vacuum drying technique in the present invention, and gained solid-state facial mask moistening effect is good, can promote wound
Face healing, good tyrosinase inhibition and inoxidizability, positive adjustment effect is played to skin microbial state, is maintained
Skin stabilization improves the colour of skin；The present invention does not add preservative, essence and surfactant, and safety is good, non-stimulated to skin,
Using low temperature drying technology, bioactie agent is protected to maintain optimum state, while effectivelying prevent microbial growth, had extensive
Safety and economic benefit.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Unless stated otherwise, the present invention uses reagent, method and apparatus is the art conventional reagents, method and apparatus.It is following
The test method of specific experiment condition is not specified in embodiment, usually according to conventional laboratory conditions or according to proposed by manufactory
Experiment condition.Unless stated otherwise, agents useful for same and raw material of the present invention can pass through commercially available acquisition.
Cellulose face paper involved in the embodiment of the present invention is the high water conservation ultra-thin face paper of highly-flexible, is with plant fiber
For raw material, adulterates cellulose nanometer fibril and obtain, with specific reference to Chinese patent application: application No. is 201810266299.3, name
Method referred to as in " a kind of high water conservation the ultra-thin face paper of highly-flexible and the preparation method and application thereof " embodiment 6 is prepared；Its
In, quantification of 10~100g/m of face paper2(preferably 60~80g/m2)。
Bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide in whitening plant polyose composition involved in the embodiment of the present invention
Can be obtained by conventional commercial (polyoses content >=90%；Preferably >=95%), it or can be prepared by self-carry.The present invention is real
Plant polyose in example is applied by self-carry preparation, it is specific the preparation method is as follows:
1, bletilla polysaccharide the preparation method comprises the following steps:
(1) bletilla striata (place of production: Zhejiang), which is dried, is broken into powder, sieves with 100 mesh sieve.Dehydrated alcohol is added and extracts degreasing 4h, takes out
Filter, is repeated 2 times, and 50 DEG C of vacuum drying drying of filter cake, the bletilla striata is put into big conical flask after accurately weighing degreasing, and distilled water is added,
Solid-liquid ratio is 1:30 (g/mL), and 70 DEG C of water-baths extract 3h, obtain filtrate with 4 layer of 200 mesh filter-cloth filtering, be repeated 2 times extraction；Merge filter
65 DEG C of rotary evaporation in vacuo are concentrated into 1/4 volume after liquid, and dehydrated alcohol is added to system volume fraction of ethanol up to 80%, stood
Night；Sediment is filtered to obtain, sediment is washed through acetone, ether, is freeze-dried up to bletilla striata Thick many candies.
(2) it is 10mg/mL that bletilla striata Thick many candies, which are redissolved through water to concentration, and by active carbon decoloring, active carbon additional amount is more
The 1%~3% of liquid glucose quality is handled 30~60 minutes under 50 DEG C of water-baths；Polysaccharide filtered fluid, is then packed by filtering at normal temperature
5000Da bag filter is purified with distillation water flowing dialysis 12h.Dialyzate is concentrated into 1/4 volume, dehydrated alcohol is added extremely
System volume fraction of ethanol is stood overnight up to 80%；Sediment is filtered to obtain, sediment is freeze-dried, it is pure to obtain the bletilla striata
Change polysaccharide, is measured through Phenol sulfuric acid procedure, polyoses content 97%.
2, pachymaran the preparation method comprises the following steps:
(1) Poria cocos (place of production: Zhejiang), which dries, is broken into powder, sieves with 100 mesh sieve.Dehydrated alcohol is added and extracts degreasing 4h, takes out
Filter, is repeated 2 times, and 50 DEG C of vacuum drying drying of filter cake, Poria cocos is put into big conical flask after accurately weighing degreasing, and distilled water is added,
Solid-liquid ratio is 1:30 (g/mL), and after 50 DEG C of water-baths are extracted 30 minutes under 400W ultrasonic wave added, then to extract under 70 DEG C of water-baths 3 small
When, filtrate is obtained with 4 layer of 200 mesh filter-cloth filtering, is repeated 2 times extraction；65 DEG C of rotary evaporation in vacuo are concentrated into 1/4 body after merging filtrate
Product is added dehydrated alcohol to system volume fraction of ethanol up to 80%, stands overnight；Sediment is filtered to obtain, sediment is through acetone, second
Ether washing, is freeze-dried up to Poria cocos Thick many candies.
(2) it is 10mg/mL that Poria cocos Thick many candies, which are redissolved through water to concentration, and by active carbon decoloring, active carbon additional amount is more
The 1%~3% of liquid glucose quality is handled 30~60 minutes under 50 DEG C of water-baths；Polysaccharide filtered fluid, is then packed by filtering at normal temperature
5000Da bag filter is purified with distillation water flowing dialysis 12h.Sediment is filtered to obtain, sediment is freeze-dried, is obtained
It to Poria cocos purified polysaccharide, is measured through Phenol sulfuric acid procedure, polyoses content 97%.
3, Radix Paeoniae Alba polysaccharide the preparation method comprises the following steps:
(1) Radix Paeoniae Alba (place of production: Zhejiang), which is dried, is broken into powder, sieves with 100 mesh sieve.Dehydrated alcohol is added and extracts degreasing 4h, takes out
Filter, is repeated 2 times, and 50 DEG C of vacuum drying drying of filter cake, Radix Paeoniae Alba is put into big conical flask after accurately weighing degreasing, and distilled water is added,
Solid-liquid ratio is 1:30 (g/mL), and 80 DEG C of water-baths extract 3 hours, obtain filtrate with 4 layer of 200 mesh filter-cloth filtering, be repeated 2 times extraction；It closes
And 65 DEG C of rotary evaporation in vacuo are concentrated into 1/4 volume after filtrate, and ethyl alcohol is added to system volume fraction of ethanol up to 80%, stood
Night；Sediment is filtered to obtain, sediment is washed through acetone, ether, is freeze-dried up to Radix Paeoniae Alba Thick many candies.
(2) it is 10mg/mL that Radix Paeoniae Alba Thick many candies, which are redissolved through water to concentration, and by active carbon decoloring, active carbon additional amount is more
The 1%~3% of liquid glucose quality is handled 30~60 minutes under 50 DEG C of water-baths；Polysaccharide filtered fluid, is then packed by filtering at normal temperature
5000Da bag filter is purified with distillation water flowing dialysis 12h.Sediment is filtered to obtain, sediment is freeze-dried, is obtained
It to Radix Paeoniae Alba purified polysaccharide, is measured through Phenol sulfuric acid procedure, polyoses content 97%.
The molecular weight of Sodium Hyaluronate involved in the embodiment of the present invention is 80~2,000,000 dalton, purity >=90%.
Polysaccharide component involved in the embodiment of the present invention is prepared via a method which to obtain: by bletilla polysaccharide, pachymaran
With Radix Paeoniae Alba polysaccharide at 4 DEG C, stirred 20 minutes under the conditions of 1000r/min；Then homogeneous stirs 10 times at 200Mpa, obtains uniformly
The polysaccharide component of system；Wherein mass ratio 1:0.01~0.8:0.01~0.8 of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide.
Embodiment 1
A kind of polysaccharide whitening solid-state facial mask, preparation method are as follows:
(1) every square metre of cellulose face paper of quality is 60g (i.e. quantification of 60g/m2)；
(2) 50 mass parts polysaccharide components, 10 mass parts Sodium Hyaluronates, 2 mass parts fresh water pearl powder (it is long to be purchased from Zhejiang
Raw bird health Science and Technology Co., Ltd.) and the mixing of 38 mass parts sterile waters；Wherein, the initial concentration of polysaccharide component is 10mg/
Ml, the mass ratio of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide is 1:0.1:0.1 in polysaccharide.Agitated device is at 4 DEG C, 600r/
Mixing under min rate 30 minutes；Using Microfluidizer, homogeneous is stirred mixture 10 times at 300Mpa, and what is obtained is uniform
System is as facial mask liquid；
(3) under 4 DEG C of gnotobasis, cellulose face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes at 70 DEG C 24 hours and consolidates to get polysaccharide whitening
State facial mask.
Embodiment 2
A kind of polysaccharide whitening solid-state facial mask, preparation method are as follows:
(1) every square metre of cellulose face paper of quality is 80g；
(2) 45 mass parts polysaccharide components, 15 mass parts Sodium Hyaluronates, 2 parts of mass parts fresh water pearl powder (are purchased from Zhejiang
Phoenix health Science and Technology Co., Ltd.) and the mixing of 38 mass parts sterile waters；Wherein, the starting addition concentration of polysaccharide component is
15mg/ml, the mass ratio of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide is 1:0.3:0.3 in polysaccharide.Agitated device at 4 DEG C,
Mixing under 1000r/min rate 20 minutes；Using Microfluidizer, homogeneous is stirred mixture 10 times at 200Mpa, is obtained
Homogeneous system as facial mask liquid；
(3) under 4 DEG C of gnotobasis, cellulose face paper is immersed in gained facial mask liquid 24 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes at 70 DEG C 24 hours and consolidates to get polysaccharide whitening
State facial mask.
Embodiment 3
A kind of polysaccharide whitening solid-state facial mask, preparation method are as follows:
(1) every square metre of cellulose face paper of quality is 80g；
(2) 20 mass parts polysaccharide components, 10 mass parts Sodium Hyaluronates, 2 mass parts fresh water pearl powder (it is long to be purchased from Zhejiang
Raw bird health Science and Technology Co., Ltd.) and the mixing of 68 mass parts sterile waters, wherein the starting of polysaccharide component adds concentration and is
10mg/ml, the mass ratio of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide is 1:0.5:0.5 in polysaccharide.Agitated device at 4 DEG C,
Mixing under 1000r/min rate 60 minutes；Using Microfluidizer, homogeneous is stirred mixture 20 times at 200Mpa, is obtained
Homogeneous system as facial mask liquid；
(3) under 4 DEG C of gnotobasis, cellulose face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes at 70 DEG C 24 hours and consolidates to get polysaccharide whitening
State facial mask.
Comparative example 1
A kind of solid-state facial mask, preparation method are as follows:
(1) commercially available face paper (being purchased from Guangzhou spunlace non-woven cloth Products Co., Ltd), is the face paper using cotton as raw material
Every square metre of quality is 60g.
(2) 50 mass parts polysaccharide components, 10 mass parts Sodium Hyaluronates, 2 mass parts pearl powders and 38 mass parts are sterile
Water mixing, wherein the initial concentration of polysaccharide component is 10mg/ml, the matter of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide in polysaccharide
Amount is than being 1:0.1:0.1.Mixing of the agitated device under 4 DEG C, 600r/min rate 30 minutes；Existed using Microfluidizer
Homogeneous stirs mixture 10 times under 300Mpa, and obtained homogeneous system is as facial mask liquid；
(3) under 4 DEG C of gnotobasis, face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes 24 hours at 70 DEG C to get solid-state facial mask.
Comparative example 2
A kind of solid-state facial mask, preparation method are as follows:
(1) commercially available face paper (being purchased from Guangzhou spunlace non-woven cloth Products Co., Ltd), be using cotton as raw material, facial mask
The quality of every square metre of paper is 60g.
(2) 20 mass parts Sodium Hyaluronates and 80 mass parts sterile waters are mixed, for agitated device at 4 DEG C, 600r/min is fast
Mixing under rate 30 minutes；Using Microfluidizer, homogeneous is stirred mixture 10 times at 300Mpa, obtained homogeneous system
As facial mask liquid；
(3) under 4 DEG C of gnotobasis, face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes 24 hours at 70 DEG C to get solid-state facial mask.
Comparative example 3
A kind of polysaccharide whitening solid-state facial mask, preparation method are as follows:
(1) every square metre of cellulose face paper of quality is 80g；
(2) 10 mass parts bletilla polysaccharides, 10 mass parts Sodium Hyaluronates and 80 mass parts sterile waters are mixed, wherein white
The starting addition concentration of splendid achnatherum polysaccharide is 15mg/ml.Mixing of the agitated device under 4 DEG C, 1000r/min rate 60 minutes；It uses
Microfluidizer homogeneous at 200Mpa stirs mixture 20 times, and obtained homogeneous system is as facial mask liquid；
(3) under 4 DEG C of gnotobasis, cellulose face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes at 70 DEG C 24 hours and consolidates to get polysaccharide whitening
State facial mask.
Comparative example 4
A kind of polysaccharide whitening solid-state facial mask, preparation method are as follows:
(1) every square metre of cellulose face paper of quality is 80g；
(2) 10 mass parts polysaccharide components (wherein polysaccharide is made of bletilla polysaccharide and Radix Paeoniae Alba polysaccharide), 10 mass parts are transparent
Matter acid sodium and the mixing of 80 mass parts sterile waters, wherein the starting addition concentration of polysaccharide component is 15mg/ml, and the bletilla striata is more in polysaccharide
The mass ratio of sugar and Radix Paeoniae Alba polysaccharide is 1:0.3.Mixing of the agitated device under 4 DEG C, 1000r/min rate 60 minutes；Using micro-
Jet homogenizer homogeneous at 200Mpa stirs mixture 20 times, and obtained homogeneous system is as facial mask liquid；
(3) under 4 DEG C of gnotobasis, cellulose face paper is immersed in gained facial mask liquid 18 hours；
(4) facial mask after the completion of dipping is dried in vacuo, temperature is 50 DEG C, the time 24 hours, dry to facial mask liquid
Transparence is presented, then seals under vacuum conditions；
(5) pasteur's method sterilizing is carried out to the solid-state facial mask of sealing, sterilizes at 70 DEG C 24 hours and consolidates to get polysaccharide whitening
State facial mask.
1 solid-state facial mask moisture absorption of effect example and performance of keeping humidity measurement
Experimental method
(1) hygroscopicity is tested: solid-state facial mask made from Examples 1 to 3 and comparative example 1~4 is respectively placed in relative humidity
For RH=43% and RH=81%, 20 DEG C of temperature of constant temperature perseverance is in incubator, and weighs each sample at regular intervals
Quality, calculate hydroscopicity=(Wn-Wo)/Wo, in formula: Wo is the quality after sample takes out from the package, and Wn is sample moisture absorption
Quality after certain time.Moisture absorption, which is calculated, by model analysis reaches saturation required time.
(2) moisture retention is tested: by moisture absorption reach the solid-state film sample of saturation constant temperature and humidity (20 DEG C of temperature, it is relatively wet
Degree weighs the quality of each sample afterwards for 24 hours, calculates moisturizing rate to continue to place for 24 hours in RH=43% and RH=81%) drying box
=Hn/Ho.In formula: Ho is quality when sample moisture absorption reaches saturation, and Hn is the quality after sample is placed for 24 hours.
Experimental result: the hygroscopicity experimental data of Examples 1 to 3 and comparative example 1~4 is as shown in table 1, moisture retention experiment
Data are as shown in table 2.Illustrate that solid-state facial mask of the invention has excellent water absorbing properties and performance of keeping humidity.
The hygroscopicity measured value of 1 Examples 1 to 3 of table and comparative example 1~4
The moisture retention measured value of 2 Examples 1 to 3 of table and comparative example 1~4
Using plant fiber as raw material, doping cellulose nanometer fibril is made the face paper that the present invention uses, and has Gao Bibiao
The characteristics of area and high-hydrophilic, the solid state bonded of facial mask liquid and face paper containing polysaccharide component, in water absorption course, polysaccharide
Swelling action occurs for molecule, while cellulose nanometer fibril hydroxyl and polysaccharide molecule form hydrogen bond and play very in conjunction with large quantity of moisture
Strong water retention.
The detection of 2 solid-state facial mask permeability of effect example
Experimental method: it is tested referring to GB/T5453-2007, pressure 100Pa, test area 20cm2。
Experimental result: the air permeability test data of solid-state facial mask made from Examples 1 to 3 and comparative example 1~4 such as table 3
It is shown.
The ventilation characteristic measuring value of 3 Examples 1 to 3 of table and comparative example 1~4
From table 3 it is known that facial mask permeability of the present invention is good, face skin is not influenced in use process and is normally exhaled
It inhales, there is good docile property and comfort.
The detection of 3 content of microorganisms of effect example.
Experimental method: it is detected in reference " cosmetics safety technical specification 2015 " requirement.
Experimental result: solid-state facial mask made from Examples 1 to 3 and comparative example 1~2 meets content of microorganisms detection mark
Standard, wherein the testing result of embodiment 2 is shown in Table 4.
The detection of 4 embodiment of table, 2 content of microorganisms
From the above it is found that solid-state facial mask is because it is stored as drying regime, it is unfavorable for the growth of microorganism, facial mask safety
Property is greatly guaranteed.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. a kind of preparation method of polysaccharide whitening solid-state facial mask, which comprises the following steps:
(1) facial mask liquid is prepared
Each raw material of facial mask liquid are mixed evenly, homogeneous is then carried out, obtains facial mask liquid；Wherein, facial mask liquid includes as follows
Component as mass fraction: 5~50 parts of polysaccharide compositions, 0~20 part of Sodium Hyaluronate, 0~5 part of pearl powder and 20~95 parts
Water；The polysaccharide composition includes bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide；
(2) polysaccharide whitening solid-state facial mask is prepared
Cellulose face paper is impregnated into the facial mask liquid that step (1) obtains, is then dried in vacuo, drying to facial mask liquid is in
Existing transparence, then sterilize, obtain polysaccharide whitening solid-state facial mask.
2. the preparation method of polysaccharide whitening solid-state facial mask according to claim 1, it is characterised in that:
Facial mask liquid described in step (1) includes following component as mass fraction: 20~50 parts of polysaccharide components, 10~15 parts
Sodium Hyaluronate, 2~5 parts of pearl powders and 30~68 parts of water.
3. the preparation method of polysaccharide whitening solid-state facial mask according to claim 1, it is characterised in that:
Polysaccharide composition described in step (1) is the polysaccharide composition of 1~500mg/ml of concentration；
Mass ratio 1:0.01~0.8:0.01~0.8 of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (1)；
The molecular weight of Sodium Hyaluronate described in step (1) is 80~2,000,000 dalton, purity >=90%；
Quantification of 10~100g/m of cellulose face paper described in step (2)2。
4. the preparation method of polysaccharide whitening solid-state facial mask according to claim 3, it is characterised in that:
Polysaccharide composition described in step (1) is the polysaccharide composition of 10~15mg/ml of concentration；
Mass ratio 1:0.1~0.5:0.1~0.5 of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (1)；
Quantification of 60~80g/m of cellulose face paper described in step (2)2。
5. the preparation method of polysaccharide whitening solid-state facial mask according to claim 1, it is characterised in that:
Bletilla polysaccharide described in step (1), pachymaran and Radix Paeoniae Alba polysaccharide are prepared via a method which to obtain:
(I) bletilla striata or Poria cocos or Radix Paeoniae Alba are dried and is broken into powder, be sieved, dehydrated alcohol is then added and extracts degreasing, filters, weight
It is 2 times or more multiple, filtering, then the filter cake being obtained by filtration is dried in vacuo, the bletilla striata or Poria cocos or Radix Paeoniae Alba after obtaining degreasing；
(II) in the bletilla striata or Poria cocos or Radix Paeoniae Alba after distilled water to be added to degreasing, solid-liquid ratio 1:30, in 70~80 DEG C of water-baths
Under the conditions of extract, filter, be repeated 2 times above, be then combined with filtrate and concentrate it to 1/4 volume, add anhydrous second
Alcohol to system volume fraction of ethanol reaches 80%, stands overnight, and finally filters, taking precipitate, and washing, freeze-drying obtain thick
Polysaccharide；
(III) by Thick many candies decoloration, purifying, concentration, freeze-drying, bletilla polysaccharide, pachymaran or Radix Paeoniae Alba after purification is obtained
Polysaccharide.
6. the preparation method of polysaccharide whitening solid-state facial mask according to claim 5, it is characterised in that:
Sieving described in step (I) is to sieve with 100 mesh sieve；
The time of degreasing described in step (I) is 4h；
Vacuum drying described in step (I) is to be dried in vacuo under the conditions of 50 DEG C；
The condition of extraction described in step (II) are as follows: under 400W ultrasonic wave added, after 50 DEG C of water-baths extract 30 minutes, then 70
DEG C water-bath is extracted 3 hours；
It is filtered into described in step (II) and is filtered using 4 layer of 200 mesh filter cloth；
Concentration described in step (II) is that rotary evaporation in vacuo is concentrated under the conditions of 65 DEG C；
Washing described in step (II) is to be washed using acetone and ether；
Decoloration described in step (III) is to be decolourized using active carbon；
Purifying described in step (III) is that molecular cut off is used to be purified for 5000Da bag filter；
Concentration described in step (III) is to be concentrated into 1/4 volume；
The polyoses content of bletilla polysaccharide, pachymaran and Radix Paeoniae Alba polysaccharide described in step (III) after purification is >=97%.
7. the preparation method of polysaccharide whitening solid-state facial mask according to claim 1, it is characterised in that:
The condition of stirring described in step (1) are as follows: 100r/min~2500r/min stirs 20~60min；
The condition of homogeneous described in step (1) are as follows: homogeneous 2~20 times under 100~300Mpa；
The condition of dipping described in step (2) are as follows: impregnated 8~24 hours under 4 DEG C of gnotobasis；
Vacuum drying condition described in step (2) are as follows: 40~60 DEG C drying 3~24 hours.
8. the preparation method of polysaccharide whitening solid-state facial mask according to claim 1, it is characterised in that: after step (2)
Further include the steps that polysaccharide whitening solid-state facial mask is sealed and is sterilized；
Described being sealed into is sealed under vacuum conditions；
The sterilizing is to be sterilized using pasteur's method, condition are as follows: sterilize 24 hours at 70 DEG C.
9. a kind of polysaccharide whitening solid-state facial mask, which is characterized in that be prepared by method according to any one of claims 1 to 8
It arrives.
10. application of the polysaccharide whitening solid-state facial mask as claimed in claim 9 in cosmetic field.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115227629A (en) * | 2022-09-05 | 2022-10-25 | 吉林一瑞生物科技有限公司 | Pilose antler moisturizing mask and preparation method thereof |
| CN115611992A (en) * | 2022-10-21 | 2023-01-17 | 上海海洋大学 | Gracilaria lemaneiformis polysaccharide and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104829875A (en) * | 2015-05-26 | 2015-08-12 | 安徽中医药高等专科学校 | Polysaccharide mixture with skin whitening effect and method for manufacturing polysaccharide mixture |
| CN108517719A (en) * | 2018-03-28 | 2018-09-11 | 华南理工大学 | Ultra-thin face paper of a kind of high water conservation highly-flexible and the preparation method and application thereof |
| CN109674729A (en) * | 2019-01-17 | 2019-04-26 | 罗贤义 | A kind of face mask of traditional Chinese medicine and its application method |
| CN109998947A (en) * | 2019-04-29 | 2019-07-12 | 深圳津梁生活科技有限公司 | Tremella skin care freeze-drying facial mask without preservative and preparation method thereof |
-
2019
- 2019-08-19 CN CN201910762692.6A patent/CN110403850B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104829875A (en) * | 2015-05-26 | 2015-08-12 | 安徽中医药高等专科学校 | Polysaccharide mixture with skin whitening effect and method for manufacturing polysaccharide mixture |
| CN108517719A (en) * | 2018-03-28 | 2018-09-11 | 华南理工大学 | Ultra-thin face paper of a kind of high water conservation highly-flexible and the preparation method and application thereof |
| CN109674729A (en) * | 2019-01-17 | 2019-04-26 | 罗贤义 | A kind of face mask of traditional Chinese medicine and its application method |
| CN109998947A (en) * | 2019-04-29 | 2019-07-12 | 深圳津梁生活科技有限公司 | Tremella skin care freeze-drying facial mask without preservative and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115227629A (en) * | 2022-09-05 | 2022-10-25 | 吉林一瑞生物科技有限公司 | Pilose antler moisturizing mask and preparation method thereof |
| CN115611992A (en) * | 2022-10-21 | 2023-01-17 | 上海海洋大学 | Gracilaria lemaneiformis polysaccharide and preparation method and application thereof |
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