CN110198954A - 与ny-eso-1结合的t细胞受体和其使用方法 - Google Patents

与ny-eso-1结合的t细胞受体和其使用方法 Download PDF

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Publication number
CN110198954A
CN110198954A CN201880006628.9A CN201880006628A CN110198954A CN 110198954 A CN110198954 A CN 110198954A CN 201880006628 A CN201880006628 A CN 201880006628A CN 110198954 A CN110198954 A CN 110198954A
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China
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seq
acid sequence
amino acid
tcr
chain
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Chinese (zh)
Inventor
M·范迪杰克
V·塞伯特
C·A·蒙特
A·A·赫维兹
M·A·埃克斯利
B·J·沃尔夫
D·利文萨尔
S·拉勒维
R·马萨卡彦
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Eiji Nath Co
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Eiji Nath Co
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/32—T-cell receptors [TCR]
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    • A61K40/41—Vertebrate antigens
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    • A61K40/4267—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A—HUMAN NECESSITIES
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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CN201880006628.9A 2017-01-13 2018-01-12 与ny-eso-1结合的t细胞受体和其使用方法 Pending CN110198954A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762446084P 2017-01-13 2017-01-13
US62/446,084 2017-01-13
PCT/US2018/013624 WO2018132739A2 (en) 2017-01-13 2018-01-12 T cell receptors that bind to ny-eso-1 and methods of use thereof

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CN110198954A true CN110198954A (zh) 2019-09-03

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US (2) US11613764B2 (enExample)
EP (1) EP3568412A2 (enExample)
JP (2) JP2020503883A (enExample)
KR (1) KR20190103226A (enExample)
CN (1) CN110198954A (enExample)
AU (1) AU2018207172B2 (enExample)
BR (1) BR112019014510A2 (enExample)
CA (1) CA3049016A1 (enExample)
EA (1) EA201991696A1 (enExample)
IL (1) IL267878A (enExample)
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