CN110192649A - 一种具有催乳通乳补气养血的配方及其制备方法 - Google Patents
一种具有催乳通乳补气养血的配方及其制备方法 Download PDFInfo
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Abstract
一种具有催乳通乳补气养血的配方及其制备方法，其配方组成为轮叶党参、蒲公英、龙眼肉、大枣、枸杞子、蓝莓。本组方能起到催乳通乳，补气养血，预防乳腺炎的作用，并且口感好，便于冲调饮用。适于产后体质虚弱，乳少、无乳和乳腺有炎症的哺乳期女性。本组方原料均为食用原材料，安全无毒副作用。
Description
技术领域
本发明涉及到一种具有催乳通乳补气养血的配方及其制备方法，属于食品和保健食品领域。
背景技术
催乳是为了帮助母乳达不到婴儿需求的产妇，由于产妇身体比较虚弱，乳量不足或全无，常用的方法有物理疗法和食疗法，物理疗法主要是催乳师进行按摩，其原理是理气活血、舒筋通络的作用。食疗法主要是通过食材的营养成分补充，其主要作用就是补气补血，疏肝理气，通畅乳腺，并且可以预防乳腺炎症等，从而增加产妇体质，促进母乳量的分泌。简单来说食疗法就是一种让产妇在哺乳期内快速调节身体机能，使乳汁分泌充足的方法。
当今社会，生活水平不断提高，为使产妇在坐月子期间快速恢复身体机能，防止月子后遗症的发生，并且保证有充足的母乳用于喂养婴儿，从而有利于婴儿的健康。为实现上述目的，制备一种便于服用，疗效显著的配方，不但可以增加母乳喂养婴儿的数量，还可以降低产妇患乳腺癌和卵巢癌的危险。
发明内容
本发明提供了一种具有催乳通乳补气养血的配方及其制备方法。
为实现上述目的，本发明提供的技术方案为：一种具有催乳通乳补气养血的配方及其制备方法，其特征在于，原料按照重量份组成为：轮叶党参1-10、蒲公英1-5、龙眼肉1-5、大枣1-5、枸杞子1-5、蓝莓1-5。
一种具有催乳通乳补气养血的配方及其制备方法，优选的重量份配比为：轮叶党参5、蒲公英1、龙眼肉1、大枣1、枸杞子1、蓝莓1。一种具有催乳通乳补气养血的配方及其制备方法，包括以下步骤：
（1）将轮叶党参和蒲公英粉碎；
（2）将龙眼肉、大枣、枸杞子、蓝莓冷冻后加入（1）的粉末继续粉碎，即得；
本发明的有益效果：本发明应用轮叶党参、蒲公英、龙眼肉、大枣、枸杞子、蓝莓的组合，能起到催乳通乳，补气养血，预防乳腺炎的作用，并且口感好，便于冲调饮用。适于产后体质虚弱，乳少、无乳和乳腺有炎症的哺乳期女性。本组方原料均为食用原材料，安全无毒副作用。
具体实施方式
实施例1
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、蒲公英1、龙眼肉1、大枣1、枸杞子1、蓝莓1。
一种具有催乳通乳补气养血的配方及其制备方法，包括以下步骤：
（1）将轮叶党参和蒲公英粉碎；
（2）将龙眼肉、大枣、枸杞子、蓝莓冷冻后加入（1）的粉末继续粉碎，即得；
实施例2
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参1、蒲公英5、龙眼肉2、大枣3、枸杞子2、蓝莓4。
操作步骤同实施例1 。
实施例3
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参3、蒲公英2、龙眼肉3、大枣5、枸杞子3、蓝莓5。
操作步骤同实施例1。
实施例4
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参10、蒲公英3、龙眼肉5、大枣2、枸杞子5、蓝莓2。
操作步骤同实施例1。
对比例1
市售催乳颗粒。
对比例2
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：蒲公英1、龙眼肉1、大枣1、枸杞子1、蓝莓1。
操作步骤同实施例1。
对比例3
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、龙眼肉1、大枣1、枸杞子1、蓝莓1。
操作步骤同实施例1。
对比例4
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、蒲公英1、大枣1、枸杞子1、蓝莓1。
操作步骤同实施例1。
对比例5
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、蒲公英1、龙眼肉1、枸杞子1、蓝莓1。
操作步骤同实施例1。
对比例6
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、蒲公英1、龙眼肉1、大枣1、蓝莓1。
操作步骤同实施例1。
对比例7
一种具有催乳通乳补气养血的配方及其制备方法，原料按照重量份组成为：轮叶党参5、蒲公英1、龙眼肉1、大枣1、枸杞子1。
操作步骤同实施例1。
本发明的动物实验方法及结论：
取产仔时间前后相差不超过24小时的大鼠，分为模型组，正常对照组，实施例1-4组，对比例1-7组，每组10只，自分娩第2日起上午给大鼠灌胃溴隐亭造模（正常对照组除外），按0.5mg/kg的剂量灌胃给药，连续7天。自分娩第2日起，正常对照组和模型组给予相应体积的蒸馏水灌胃，实施1-4和对比例1-7给予相应的配方，剂量为20g/kg，每日1次，各组均灌胃14天， 从灌胃第2日开始，每日将仔鼠与母鼠隔离5h后，用手指轻压仔鼠腹部以排出尿液后，称量全窝体重，然后将仔鼠送回母鼠身边哺乳，吮乳1h后再次称仔鼠体重，比吮乳前增加的体重为全窝仔鼠单次泌乳量。血清泌乳素（prolaction，PRL）测定，实验结束后，各组大鼠腹腔注射水合氯醛麻醉（每10g体重0.04mL），下腔静脉取血，常温静置30min，3500r/min，4℃离心15min，分离血清，采用酶联免疫吸附测定法（ELISA法）严格按照试剂盒说明书步骤测定PRL含量。下丘脑5-羟色胺（5-hydroxytryptamine，5-HT）测定，采血后的母鼠，取脑备用。准确称量取材的下丘脑0.1g，加入2mL 酸性正丁醇（500mL正丁醇中加入0.85mL浓盐酸）进行组织匀浆，匀浆后再振荡5min，3000r/min 离心10min，取上清，采用ELISA法严格按照试剂盒说明书步骤测定5-HT含量。测定结果见表1。
表1：缺乳大鼠单次泌乳量及PRL和5-HT的结果
| 组别 | 单次泌乳量（g） | PRL含量（ng/ml） | 5-HT含量（ng/ml） |
| 实施例1 | 0.65±0.12** | 117.53±15.16** | 76.74±13.68** |
| 实施例2 | 0.62±0.11** | 114.33±13.46** | 74.25±14.36** |
| 实施例3 | 0.60±0.13** | 113.84±11.58** | 72.74±15.76** |
| 实施例4 | 0.59±0.10** | 112.36±12.35** | 71.22±12.36** |
| 对比例1 | 0.55±0.12** | 106.52±14.35** | 63.91±13.02** |
| 对比例2 | 0.40±0.09* | 81.39±11.46* | 47.29±11.35* |
| 对比例3 | 0.41±0.11* | 85.01±11.27* | 50.76±15.71* |
| 对比例4 | 0.44±0.13* | 84.76±12.71* | 49.72±13.76* |
| 对比例5 | 0.43±0.12* | 83.22±12.36* | 47.22±11.36* |
| 对比例6 | 0.42±0.11* | 82.93±12.02* | 48.93±13.02* |
| 对比例7 | 0.41±0.12* | 81.26±11.69* | 46.26±10.38* |
| 正常对照组 | 0.51±0.13** | 109.89±11.58** | 59.89±15.58** |
| 模型组 | 0.29±0.10 | 69.02±12.27 | 33.89±13.14 |
与模型组比较：**P﹤0.01；*P﹤0.05
结果显示，本发明实施例1-4制得的产品能明显提高缺乳大鼠单次泌乳量，血清中PRL含量及下丘脑5-HT含量。PRL在泌乳过程的启动和维持中起着重要作用，是促进泌乳发生的主要激素。下丘脑分泌的5-HT作为一种中枢神经系统递质，能促进PRL的分泌，从而增加泌乳量。
本发明的组合物共观察缺乳患者120例，年龄在21岁到41岁之间，口服本发明实施例1制得的粉末，每日2次，每次10克，7天为一个治疗周期，在治疗1-2个周期后，其中效果显著的108例，占90%，有效10例，占8.3%，无效2例，占1.7%。总有效率为98.3%。典型案例如下：
案例1：
肖某，23岁，女，产后无乳，面色无华萎黄，皮肤干燥。服用实施例1制得的粉末7天后，乳量充足，面色红润。
案例2：
王某，女，39岁，产后乳量不足， 虚弱无力，服用实施例1制得的粉末7天后。乳量充足，人也精神多了。
通过上述验证，被观察者一致认为本发明的组合物效果明显，安全无毒副作用，具有催乳通乳，补气养血的作用，表明本产品是一款很好的健康食品。
上述内容是对本发明的说明，不是对本发明的限定，任何对本发明简单变换后的方案均属于本发明的保护范围。
Claims (3)
1.一种具有催乳通乳补气养血的配方及其制备方法，其特征在于，原料按照重量份组成为：轮叶党参1-10、蒲公英1-5、龙眼肉1-5、大枣1-5、枸杞子1-5、蓝莓1-5。
2.根据权利要求1所述的一种具有催乳通乳补气养血的配方及其制备方法，优选的重量份配比为：轮叶党参5、蒲公英1、龙眼肉1、大枣1、枸杞子1、蓝莓1。
3.一种权利要求1和2所述的一种具有催乳通乳补气养血的配方及其制备方法，包括以下步骤：
（1）将轮叶党参和蒲公英粉碎；
（2）将龙眼肉、大枣、枸杞子、蓝莓冷冻后加入（1）的粉末继续粉碎，即得。
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