CN110151899A - A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse - Google Patents
A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse Download PDFInfo
- Publication number
- CN110151899A CN110151899A CN201910582835.5A CN201910582835A CN110151899A CN 110151899 A CN110151899 A CN 110151899A CN 201910582835 A CN201910582835 A CN 201910582835A CN 110151899 A CN110151899 A CN 110151899A
- Authority
- CN
- China
- Prior art keywords
- fighting
- fermentation
- hpv viruse
- chinese medicine
- raw material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The invention discloses a kind of Chinese medicine draft formulas and its fermentation preparation for fighting HPV viruse, including following raw material: safflower, wormwood, imperial camphor, thyme, cordate houttuynia, garlic.The present invention has preferable preventive effect to HPV viruse, natural herb ingredient, sterile fermentation technology, without any hormone and side effect, it can be used for a long time, medical fluid effective component concentration is high, molecule is allowed to become smaller by fermentation, it can be rapidly absorbed, with activating microcirculation and removing stasis medicinal, dispelling cold and removing dampness, the effect of antivirus degerming, patient's immunity can be increased, promote wound healing, activating cell, fight ischemic and the damage of the circulatory system, with bidirectional modulation and protective effect, there is apoptosis-promoting effect to mutant, it can induce cancer cell-apoptosis, it can accelerate internal peroxide, block the synthesis of carcinogen nitrosamine, restrain growth of cancer cells, there is lethal effect to cancer cell.
Description
Technical field
The present invention relates to field of pharmaceutical technology more particularly to a kind of Chinese medicine draft formula for fighting HPV viruse and its fermentations
Preparation method.
Background technique
HPV viruse is the abbreviation of human papilloma virus, is a kind of papilloma vacuolating virus A for belonging to papovaviridae
Belong to, be spherical DNA virus, the scaly epithelium of human skin mucous membrane can be caused to be proliferated, separated at present more than 130 kinds out, correlation is ground
Study carefully proof, 99.7% cervical carcinoma is all that HPV viruse infection is caused, as long as women has sexual intercourse, it is possible to infect
HPV viruse, global 6.3 hundred million people are infected by HPV viruse, just have 1 people to die of cervical carcinoma within every 3 minutes.
It is to touch virus infection body because in function of human body immunity degradation why the mankind, which infect HPV viruse,
After, HPV viruse is replicated in cuticular cellulose, and HPV invades nucleus, causes cell to divide rapidly, while associated virus particle
Breeding with send out, form characteristic papilloma；
Fight HPV viruse method the most scientific are as follows: increase immunity of organisms, kill mutant, activating cell, promote
Cuticle of cell regeneration is with the automatic adjustment of, organism balance, and the drug currently used for treatment HPV viruse infection is mostly Western medicine, curative effect
Slowly, medicining cycle is long, and long-term use is larger to the side effect of patient, can cause patient's anorexia, exempt from so that patient's body can be reduced
Epidemic disease power is based on this, it is proposed that a kind of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse.
Summary of the invention
Technical problems based on background technology, the invention proposes a kind of Chinese medicine draft formulas for fighting HPV viruse
And its fermentation preparation, for the treatment and prevention to HPV viruse.
A kind of magistral medicines fighting HPV viruse proposed by the present invention, including following raw material: safflower, wormwood, imperial camphor,
Thyme, cordate houttuynia, garlic.
Preparation method includes the following steps:
S1: raw material selection: from regular market choose the higher safflower of quality, wormwood, imperial camphor, thyme, cordate houttuynia,
Then garlic is sorted and is cleaned to medicinal material respectively, removal rotten leaf slightly obstructs and silt, after drying, is respectively cut every kind of medicinal material
It is broken.
S2: it weighs: in the desired amount, every kind of medicinal material being weighed using electronic scale, it is then that the medicinal material after weighing is uniform
It is admixed together, obtain mixed raw material A.
S3: medical fluid extracts: mixed raw material A described in S2 being put into an irony or ceramic closed container, then
Closed container is heated with mild fire, until mixed raw material A is carbonized, in this course, by condensation pipe by closed row
Gas out is guided into another clean glass container, and the interlude of condensation pipe is cooled down using cold water, makes gas liquid
Change, in this way, drug crude liquid B can be obtained in glass container.
S4: fermentation: the glass container for filling drug crude liquid B described in S3 is sealed, shady and cool ventilation is then placed into
Place after being left to ferment a period of time, obtains fermentation mixed liquor C.
S5: primary removal of impurities processing: first skimming the upper oil for the mixed liquor C that ferments described in S4, then that residue is mixed
It closes liquid to be filtered with strainer, removes lower sediment thing, obtain semi-finished product medical fluid D.
S6: secondary removal of impurities processing: semi-finished product medical fluid D described in S5 is handled through oil water separator, after collection
Obtain finished product medical fluid E.
Preferably, the safflower, wormwood, imperial camphor, thyme, cordate houttuynia and the dosage of garlic are 1: 1 by weight:
1∶1∶1∶1。
Preferably, in the S2, the model SZ-A53 of electronic scale, specification 7.5kg/0.2g.
Preferably, in the S4, the fermentation time of drug crude liquid B is 30-40 days.
Preferably, in the S5, screen specification used is 120 mesh.
Preferably, in the S6, the model WGS-300 of oil water separator.
Discussion to formula:
[safflower]
Function are as follows: activating microcirculation and removing stasis medicinal dissipates Yu Kaijie, women's menostasis, postpartum blood stasis abdominal pain, tumbling and swelling.
[wormwood]
Ai Yiye is used as medicine, warm-natured, bitter, nontoxic, ripe heat, there is regulating menstruation, hemostasis, miscarriage prevention only to collapse, dispelling cold and removing dampness the benefits of.
[borneol camphor tree]
The king of herbal hundred medicines: blood-brain barrier is easily penetrated.Remarkably promote drug absorption.Can fight the circulatory system ischemic and
Damage.Central nervous system has bidirectional modulation and protective effect.There are very strong antibacterial, anti-inflammatory, antitoxin, analgesic activity.It can be bright
It is aobvious to promote wound healing.Increase granulation tissue structure and reepithelialization, repairs skin accessory organ and there is stronger wound
Hurt Healing.There is apoptosis-promoting effect to mutant, can induce cancer cell-apoptosis.
[thyme]
Have promote blood circulation of human body, strengthen immunity, mitigate neuropathic pain, antibacterial, have promote wound healing, control
Treat eczema, activating cell, the effect for improving memory and attention.
[cordate houttuynia]
Modern pharmacology experiment shows that cordate houttuynia has the effects that antibacterial, antiviral, raising immunity of organisms, diuresis.
[garlic]
The allicin contained in garlic has broad-spectrum antibacterial action, it is to meningomyelitis virus, common cold virus, B-mode brain
A variety of pathogenic microorganisms such as scorching virus, hepatitis virus, Diplococcus pneumopniae have killing effect.Garlic can block carcinogenic substance
The synthesis of matter --- nitrosamine restrains growth of cancer cells, has lethal effect to cancer cell.The selenium that garlic includes can accelerate body
Endoperoxides object restrains cancer cell.
Beneficial effects of the present invention: the present invention has preferable preventive effect, natural herb ingredient, pure bacterium hair to HPV viruse
Ferment technology is free of any hormone and side effect, can be used for a long time, and medical fluid effective component concentration is high, allows molecular change by fermentation
It is small, it can be rapidly absorbed, have the function of activating microcirculation and removing stasis medicinal, dispelling cold and removing dampness, antivirus degerming, patient's immunity can be increased, promote wound
Mouth healing, activating cell fight ischemic and the damage of the circulatory system, have bidirectional modulation and protective effect, have to mutant
Apoptosis-promoting effect can induce cancer cell-apoptosis, can accelerate internal peroxide, block the synthesis of carcinogen nitrosamine, restrain
Growth of cancer cells has lethal effect to cancer cell.
Specific embodiment
Combined with specific embodiments below the present invention is made further to explain.
Embodiment
A kind of magistral medicines for fighting HPV viruse, including following raw material: safflower, wormwood, imperial camphor tree are proposed in the present embodiment
Brain, thyme, cordate houttuynia, garlic；
Its production method the following steps are included:
S1: raw material selection: from regular market choose the higher safflower of quality, wormwood, imperial camphor, thyme, cordate houttuynia,
Then garlic is sorted and is cleaned to medicinal material respectively, removal rotten leaf slightly obstructs and silt, after drying, is respectively cut every kind of medicinal material
It is broken.
S2: it weighs: in the desired amount, every kind of medicinal material being weighed using electronic scale, it is then that the medicinal material after weighing is uniform
It is admixed together, obtain mixed raw material A.
S3: medical fluid extracts: mixed raw material A described in S2 being put into an irony or ceramic closed container, then
Closed container is heated with mild fire, until mixed raw material A is carbonized, in this course, by condensation pipe by closed row
Gas out is guided into another clean glass container, and the interlude of condensation pipe is cooled down using cold water, makes gas liquid
Change, in this way, drug crude liquid B can be obtained in glass container.
S4: fermentation: the glass container for filling drug crude liquid B described in S3 is sealed, shady and cool ventilation is then placed into
Place after being left to ferment a period of time, obtains fermentation mixed liquor C.
S5: primary removal of impurities processing: first skimming the upper oil for the mixed liquor C that ferments described in S4, then that residue is mixed
It closes liquid to be filtered with strainer, removes lower sediment thing, obtain semi-finished product medical fluid D.
S6: secondary removal of impurities processing: semi-finished product medical fluid D described in S5 is handled through oil water separator, after collection
Obtain finished product medical fluid E.
Safflower, wormwood, imperial camphor, thyme, cordate houttuynia and the dosage of garlic are 1: 1: 1: 1: 1: 1 by weight；S2
In, the model SZ-A53 of electronic scale, specification 7.5kg/0.2g；In S4, the fermentation time of drug crude liquid B is 30-40 days；S5
In, screen specification used is 120 mesh；In S6, the model WGS-300 of oil water separator.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (7)
1. a kind of magistral medicines for fighting HPV viruse, which is characterized in that including following raw material: in safflower, wormwood, imperial camphor, hundred
Perfume, cordate houttuynia, garlic.
2. a kind of production method for the magistral medicines for fighting HPV viruse, which comprises the following steps:
S1: the higher safflower of quality, wormwood, imperial camphor, Bai Lixiang, cordate houttuynia, big raw material selection: is chosen from regular market
Then garlic is sorted and is cleaned to medicinal material respectively, removal rotten leaf slightly obstructs and silt, after drying, is respectively shredded every kind of medicinal material.
S2: it weighs: in the desired amount, every kind of medicinal material being weighed using electronic scale, then uniformly mixes the medicinal material after weighing
To together, obtaining mixed raw material A.
S3: medical fluid extracts: mixed raw material A described in S2 being put into an irony or ceramic closed container, then with text
Fire heats closed container, until mixed raw material A is carbonized, in this course, by condensation pipe by closed discharge
Gas is guided into another clean glass container, and the interlude of condensation pipe is cooled down using cold water, makes gas liquefaction, such as
This, can be obtained drug crude liquid B in glass container.
S4: fermentation: the glass container that drug crude liquid B is filled described in S3 is sealed, and is then placed at shady and cool ventilation, quiet
After setting fermentation a period of time, fermentation mixed liquor C is obtained.
S5: primary removal of impurities processing: first the upper oil for the mixed liquor C that ferments described in S4 is skimmed, then by residual mixed liquor
It is filtered with strainer, removes lower sediment thing, obtain semi-finished product medical fluid D.
S6: secondary removal of impurities processing: semi-finished product medical fluid D described in S5 is handled through oil water separator, after collection, can be obtained
Finished product medical fluid E.
3. a kind of production of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse according to claim 1
Method, which is characterized in that the safflower, wormwood, imperial camphor, thyme, cordate houttuynia and the dosage of garlic are 1: 1 by weight
∶1∶1∶1∶1。
4. a kind of production of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse according to claim 3
Method, which is characterized in that in the S2, the model SZ-A53 of electronic scale, specification 7.5kg/0.2g.
5. a kind of production of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse according to claim 3
Method, which is characterized in that in the S4, the fermentation time of drug crude liquid B is 30-40 days.
6. a kind of production of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse according to claim 3
Method, which is characterized in that in the S5, screen specification used is 120 mesh.
7. a kind of production of Chinese medicine draft formula and its fermentation preparation for fighting HPV viruse according to claim 3
Method, which is characterized in that in the S6, the model WGS-300 of oil water separator.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910582835.5A CN110151899A (en) | 2019-06-28 | 2019-06-28 | A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910582835.5A CN110151899A (en) | 2019-06-28 | 2019-06-28 | A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110151899A true CN110151899A (en) | 2019-08-23 |
Family
ID=67637090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910582835.5A Pending CN110151899A (en) | 2019-06-28 | 2019-06-28 | A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110151899A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908559A (en) * | 2012-09-26 | 2013-02-06 | 韩临晓 | External-use Chinese herbal medicine preparation for curing human papilloma virus infection |
| CN106728762A (en) * | 2017-03-14 | 2017-05-31 | 贵州灿石正科信息咨询服务有限公司 | It is a kind of to treat Chinese medicine composition of cervical carcinoma and preparation method thereof |
| CN107961265A (en) * | 2017-12-19 | 2018-04-27 | 杨平芝 | A kind of gynecological gel prevented and suppress HPV viruse |
| CN108721449A (en) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | One kind effectively enhancing the gel of anti-HPV infection for inhibiting HPV infection |
-
2019
- 2019-06-28 CN CN201910582835.5A patent/CN110151899A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908559A (en) * | 2012-09-26 | 2013-02-06 | 韩临晓 | External-use Chinese herbal medicine preparation for curing human papilloma virus infection |
| CN106728762A (en) * | 2017-03-14 | 2017-05-31 | 贵州灿石正科信息咨询服务有限公司 | It is a kind of to treat Chinese medicine composition of cervical carcinoma and preparation method thereof |
| CN107961265A (en) * | 2017-12-19 | 2018-04-27 | 杨平芝 | A kind of gynecological gel prevented and suppress HPV viruse |
| CN108721449A (en) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | One kind effectively enhancing the gel of anti-HPV infection for inhibiting HPV infection |
Non-Patent Citations (1)
| Title |
|---|
| 覃晓洵等: "中医药治疗宫颈人乳头瘤病毒感染的临床研究进展", 《河北中医》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105796960A (en) | Traditional Chinese medicine liquid for caring and cleaning wounds | |
| CN1679888A (en) | Decoction Chinese medicine sterilizing antiphlogistic, preparation and use thereof | |
| CN103751633A (en) | Traditional Chinese medicinal composition for treating varicose vein of lower limb and preparation method thereof | |
| CN105169017A (en) | Traditional Chinese medicine for treating kidney stone and preparation method of traditional Chinese medicine | |
| CN105106318B (en) | A kind of Chinese medicine composition and preparation method thereof for treating xerophthalmia | |
| CN102949662B (en) | External traditional Chinese medicine preparation for treating female reproductive system inflammation and preparation method thereof | |
| CN104306712A (en) | Heat clearing and detoxifying tea and preparation method thereof | |
| CN103599409B (en) | One treats prosopalgic Chinese medicine composition | |
| CN111110785A (en) | Carbuncle block eliminating ointment for treating cancer pain and preparation method thereof | |
| CN110151899A (en) | A kind of Chinese medicine draft formula and its fermentation preparation fighting HPV viruse | |
| CN105998400A (en) | Traditional Chinese medicine composition for preventing and treating duck plague and preparation method thereof | |
| CN104922449A (en) | Traditional Chinese medicine disinfection solution and preparation method thereof | |
| CN105770074A (en) | Traditional Chinese medicine composition for treating wind-heat common cold and preparation method thereof | |
| CN104971271A (en) | Medicine for treating benign prostatic hyperplasia due to damp-retained heat and preparation method thereof | |
| CN104606566A (en) | Traditional Chinese medicine composition for treating liver-yang hyperactivity hypertension and preparation method for traditional Chinese medicine composition | |
| CN103845628A (en) | Medicine for treating cat tetanus and preparation method of medicine | |
| CN109200233A (en) | A kind of drug and preparation method thereof for treating pheretima bacteriosis | |
| CN106039160A (en) | Compound datura flower external medicated wine | |
| CN107050286A (en) | It is a kind of to treat deaf, decoction medicine of tinnitus and preparation method thereof | |
| CN105214041A (en) | Sang Ju Yin Chinese medicinal liquor | |
| CN105920360A (en) | Pharmaceutical composition containing radix paeoniae alba and fruit of Chinese wolfberry for preventing and treating eye diseases | |
| CN105688038A (en) | Tetanus mixture and preparation method thereof | |
| CN104958687A (en) | Traditional Chinese medicine for treating keratitis | |
| CN1552428A (en) | External antifungal Chinese medicine composition | |
| CN104367654A (en) | Raspberry-containing pharmaceutical composition for treating diarrhea |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Wu Jiangping Document name: Notification of Passing Preliminary Examination of the Application for Invention |
|
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190823 |