CN105688038A - Tetanus mixture and preparation method thereof - Google Patents

Tetanus mixture and preparation method thereof Download PDF

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Publication number
CN105688038A
CN105688038A CN201610092924.8A CN201610092924A CN105688038A CN 105688038 A CN105688038 A CN 105688038A CN 201610092924 A CN201610092924 A CN 201610092924A CN 105688038 A CN105688038 A CN 105688038A
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weight portion
parts
radix
herba
tetanus
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况晓文
李文娟
高利红
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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Abstract

The invention discloses a tetanus mixture. The tetanus mixture comprises, by weight, 25-30 parts of gecko, 25-30 parts of Scolopendra, 25-30 parts of scorpion, 25-30 parts of Bombyx Batryticatus, 20-30 parts of Periostracum Cicada, 25-30 parts of Herba Dendrodii Officinalis, 25-30 parts of tamariskoid spikemoss herb, 12-15 parts of Arisaema Cum Bile, 12-15 parts of Radix Saposhnikoviae, 12-15 parts of Herba Schizonepetae, 6-8 parts of hirudo, 6-8 parts of Radix Angelicae, 6-8 parts of Angelica Sinensis, 6-8 parts of Radix Paeoniae Alba, 6-8 parts of Rhizoma Gastrodiae, 6-12 parts of Ramulus Uncariae Cum Uncis, 6-8 parts of Pheretima, 6-8 parts of Radix Salviae Miltiorrhizae, 6-8 parts of Rhizoma Curcumae Longae, 6-12 parts of goat milk and 3-4 parts of Radix Glycyrrhizae. The tetanus mixture is remarkably effective through clinical application, is free of obvious toxic or side effect by being a pure traditional Chinese medicine preparation, can be prepared massively once and is convenient to carry and take.

Description

A kind of Poshangfeng mixture and preparation method
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Poshangfeng mixture and preparation method。
Background technology
Tetanus is clostridium tetani invades human body, growth and breeding under anaerobic environment via skin or mucosa wound, produces toxin and causes a kind of specific infection of paroxysmal muscular spasm。Tetanus is generally 7~8 days incubation period, can be as short as 24 hours or up to several months, several years。Incubation period short person, prognosis is more poor。The patient of about 90% morbidity in injured latter 2 weeks, there is tetanus signs after extracing the internal foreign body retained for many years in accidental patient。
Chinese medicine thinks tetanus, name of disease。Have another name called tetanus, lock jaw due to metallic implement injury, puerperal tetanus in incised wound。This cause of disease ailment said due to cold or exposure invades caused by damaged wound or the open sore part, and disease sees that patient is from the beginning of namely feeling aversion to cold, general malaise or grade fever, headache, two cheeks are ached, the micro-sense anxiety of lower jaw, slightly difficult during crunching, neck rotation is ineffective, and then facial spasm, in risus sardonicus, gnathospasma, stiff tongue locked mouth, sialorrhea, even whole-body muscle persistency tetanic spasm, opisthotonus, can show effect again and again, last language, swallow, breathe equal difficulty, even be choked to death。"Nei Jing" is said: pathogenic wind being the primary pathogen in causing exogenous diseases, peace and quiet, and space between skin and muscles closes to be refused, though there being extremely poisonous pathogens, and not can cause harm also。With regard to tetanus demonstrate,prove, because thing breaks up skin and flesh, be often considered as ordinary, hardly realize ailment said due to cold or exposure take advantage of a weak point in opponent's defence and visitor attacks it, gradually to become dislike wait。All skin ulcers are not healed up for a long time again, ailment said due to cold or exposure also can in attack, or use soup drip washing, or Chinese mugwort burn moxibustion, the poisonous gas of its soup fire, be also as good as with tetanus heresy。It for card also, all can propagate meridians, burns bright vital qi, is with cold and heat catch cropping, and very then locked mouth order is oblique, orthotonus, such as the shape of opisthotonus, extremely in this morning or evening, really can have pity on!Control method, when same typhoid fever punish, because it has at table, in difference inner, half exterior and half interior three, thus not from antiperspirant, under and three methods also。Be thus diaphoresis it, at inner person's purgation, between the exterior and the interior, person should conciliate it, can not cross its method also again。Neighbourhood of commoners savage, fails to see this card more and kills a person easy, early do not see the doctor for treatment, and hands of tucking inside the sleeve is awaited death, Alas!
Tetanus name of disease head sees Song dynasty Holy Benevolent Prescriptions, cloud: " orthotonus, locked mouth can not be opened, and extremity tremble, diaphysis pain, appearance fish sticking its mouth out of the water tiltedly, this all damages in ailment said due to cold or exposure in part, therefore named tetanus。"
The cause of disease is the broken wound of skin and flesh, experiences again the heresy of pathogenic wind toxic。The heresy of pathogenic wind toxic takes advantage of that skin and flesh is broken hinders in part invasion and attack people, wind being YANG-pathogen, benefaction and number becomes, exogenous wind priming liver-wind stirring up internally, with the passing of time pathogenic wind toxic people invades, heat-transformation fire-transformation, makes zang-fu disharmony, qi-blood disharmony, deficiency of YIN affecting YANG, even dissociation of YIN from YANG and dead。
Current needleless is to tetanic Special Traditional Chinese Medicine patent medicine, only provisional prescription and Western medicine antitetanic extract for treating, interim prescription Traditional Chinese medicine decocting, and the time is longer, bothersome effort, and can not disposable produce in enormous quantities, inconvenient to carry。Western medicine antitetanic extract for treating is easily generated untoward reaction, somewhat expensive, and it cannot be guaranteed that prognosis bona。It is easily generated untoward reaction。Such as anaphylactic shock: can occurring in several minutes or several tens minutes in injection or after injection, patient is irritated or dull suddenly, pale complexion, uncomfortable in chest or asthma is in a cold sweat, and pulse is carefully fast, blood pressure drops, and severe patient rescues not in time can be dead。Can alleviate after the lighter's Injection of Adrenaline;Severe patient must be cured by oxygen therapy, and uses pressor agent, antiallergic agent and adrenocortical hormone etc. to rescue。
Summary of the invention
It is an object of the invention to overcome above-mentioned technical problem and a kind of evident in efficacy, effective, Shorten the Treatment Process, pure Chinese medicinal preparation, Poshangfeng mixture without obvious toxic-side effects are provided。
The preparation method that another object of the present invention provides above-mentioned Poshangfeng mixture。
For achieving the above object, the present invention adopts the following technical scheme that a kind of Poshangfeng mixture, including following component by weight: Gekko Swinhonis 25-30 weight portion, Scolopendra 25-30 weight portion, Scorpio 25-30 weight portion, Bombyx Batryticatus 25-30 weight portion, Periostracum Cicadae 20-30 weight portion, Herba Dendrobii 25-30 weight portion, Herba Hylothelephii Verticillati 25-30 weight portion, Arisaema Cum Bile 12-15 weight portion, Radix Saposhnikoviae 12-15 weight portion, Herba Schizonepetae 12-15 weight portion, Hirudo 6-8 weight portion, Radix Angelicae Dahuricae 6-8 weight portion, Radix Angelicae Sinensis 6-8 weight portion, Radix Paeoniae Alba 6-8 weight portion, Rhizoma Gastrodiae 6-8 weight portion, Ramulus Uncariae Cum Uncis 6-12 weight portion, Pheretima 6-8 weight portion, Radix Salviae Miltiorrhizae 6-8 weight portion, Rhizoma Curcumae Longae 6-8 weight portion, Lac caprae seu ovis 6-12 weight portion, Radix Glycyrrhizae 3-4 weight portion。
A kind of preparation method stating Poshangfeng mixture, comprises the following steps:
(1) weighing each medicine according to prescription, take Radix Angelicae Sinensis, Rhizoma Curcumae Longae, Rhizoma Gastrodiae 6-8 times of weight parts water of addition, soak 2-3 hour, distillation extraction 1.5-2 hour, collect volatile oil, it is standby that addition beta-schardinger dextrin-makes clathrate, medicinal residues and debris;
(2) by step 1 Chinese medicine slag and Gekko Swinhonis, Scolopendra, Scorpio, Bombyx Batryticatus, Periostracum Cicadae, Herba Dendrobii, Herba Hylothelephii Verticillati, Arisaema Cum Bile, Radix Saposhnikoviae, Herba Schizonepetae, Hirudo, the Radix Angelicae Dahuricae, the Radix Paeoniae Alba, Ramulus Uncariae Cum Uncis, Pheretima, Radix Salviae Miltiorrhizae, Lac caprae seu ovis, Radix Glycyrrhizae merges, soak 2-3 hour, decoct twice, 2-2.5 hour first time, second time 1-1.5 hour, collecting decoction, filter, filtrate is concentrated into 500ml, add 2 times amount ethanol, stirring, stand 36 hours, filter, decompression filtrate recycling ethanol adds water to 1000ml, stand 36 hours, filter, add clathrate in step 1, add distilled water to adjust to 2000ml, stir evenly, stand 1 hour, filter, fill, put into high-temperature sterilization cabinet sterilizing, it is qualified to check, subpackage, obtain 100ml/ bottle, obtain。
Beneficial effect: said preparation is evident in efficacy by clinic application, and be pure Chinese medicinal preparation, without obvious toxic-side effects, make patent medicine, disposable can produce in enormous quantities, carry taking convenience。
Medication mechanism:
Gekko Swinhonis: salty in the mouth;Cold in nature。Liver Channel。Expelling wind for relieving convulsion;Detoxicating and resolving stagnation of pathogens。Main severe and migratory arthralgia pain;Extremity are unsuccessful;Infantile convulsion;Tetanus, carbuncle scrofula;Leprosy;Tinea corporis;Dysphagic。For paralysis due to windstroke, rheumatic arthritis, osteomyelitis, tuberculous lymphadenitis, tumor。" detailed outline ": controlling paralysis due to windstroke, brothers do not lift, or severe and migratory arthralgia pain, and puerperal tetanus infantile convulsion, infantile emaciation, accumulation of blood becomes painful abdominal mass, strict wind scrofula;Treat scorpion sting。" Traditional Chinese Medicine in Sichuan will ": wind dispelling, removing blood stasis amasss enclosed mass, controls and swells and ache。
Scolopendra: pungent, temperature;Poisonous。Return Liver Channel。Endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation。For liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula, snake bite and insect sting。" detailed outline ": " control pediatric epilepsy scared tetany caused by wind pathogen, infantum tetanus locked mouth, erysipelas, tinea alba, scrofula, inguinal bubo, anal fistula, Serpentis abdominal mass, thecal whitlow, snakebite。" " beautiful Chinese catalpa medicine solution ": " dials pus detumescence。"
Scorpio: pungent, flat;Poisonous。Return Liver Channel。Endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation。For liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula。" Kaibao Bencao ": " treating all urticarias and apoplexy and hemiplegia, facial hemiparalysis, language is puckery, spasm of hands and feet。" " book on Chinese herbal medicine can be compiled ": " tetanus should based on Scorpio, Radix Saposhnikoviae。"
Bombyx Batryticatus: salty, pungent is flat。Return liver, lung, stomach warp。Endogenous wind stopping relieving convulsion, wind-expelling pain-stopping, dissipating phlegm and resolving masses。Pressing from both sides expectorant for liver-wind, convulsion with spasms, children's counts frightened, tetanus, whirlpool, middle air port, headache due to pathogenic wind-heat, conjunctival congestion pharyngalgia, rubella pruritus, maxillofacial sore Zha。Control apoplexy facial hemiparalysis, hemiplegia: Rhizoma Typhonii, Bombyx Batryticatus, each decile of Scorpio (and giving birth to use)。For smalls。Often take a money, under hot wine is adjusted, when being regardless of。(" Young man Tibetan side " QIANZHENGSAN)
Periostracum Cicadae: sweet, cold。Return lung, Liver Channel。Dissipate wind heat extraction, sore-throat relieving, rash, improving acuity of vision and removing nebula, spasmolytic。For anemopyretic cold, pharyngalgia hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus。
Herba Dendrobii: sweet in the mouth, cold nature。Promote the production of body fluid nourishing the stomach;Nourishing YIN and clearing away heat;Lung moistening kidney tonifying;The strong waist of improving eyesight。The modern study effect of promoting the production of body fluid: Herba Dendrobii has the effect of promoting the production of body fluid, main manifestations is for promoting glandular secretion and internal organs motion。Hypoglycemic activity: Herba Dendrobii brings out glycosuria blood glucose value to reducing streptozotocin。Enhancing human body immunity power: Herba Dendrobii granule (TPSH) can promote the phagocytic function of tumor animal macrophage, strengthen the activity of the lymphocytic propagation of T and differentiation and NK cell, and the serum hemolysin value of tumor animal can be significantly improved, no matter prompting TPSH is to non-specific immunity, or specific cellular immunity and humoral immune function, all improve effect。
Herba Hylothelephii Verticillati: pained is flat。Promoting blood circulation to restore menstrual flow。Cure mainly amenorrhea;Lump in the abdomen;Traumatic injury;Stomachache;Asthma;Spit blood;Have blood in stool;Hematuria;Epistaxis。Modern study: antitumaous effect: chemical anticancer agents or radiotherapy sensitivity tumor is all effective;It is usually used in chorionic epithelioma, malignant mole, rhinocarcinoma, pulmonary carcinoma, hepatocarcinoma。It has been experienced that: the hot water extract of Herba Selaginellae herb, measure by total cell volume method, be 61.2% to murine sarcoma-180% suppression ratio, the suppression ratio of ethanol extraction is 18.6%;This product experiment in vivo, has certain inhibitory action, and can extend the life-span of transplantation tumor animal mice ehrlich carcinoma。Its equal plant Herba Selaginellae Doederleinii (selaginella doederleinii) experiment in vitro, also has the effect of higher active anticancer。Clinical practice is observed: the cancerous protuberance curative effect that tumor body is less is best。Anastalsis: Herba Selaginellae is fried with having anastalsis。Bacteriostasis: 100% Herba Selaginellae decoct flat board burrows method, and staphylococcus aureus is had inhibitory action。Spasmolysis: smooth muscle is had moderate spasmolysis by contained versulin。Also more weak anti-ulcer effect is shown through Cavia porcellus and rat experiment。
Arisaema Cum Bile: bitter, micro-pungent is cool。Return lung, liver, spleen channel。Removing heat-phlegm, dispelling wind and relieving convulsion。For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion。Clearing away fire and eliminating phlegm, relieving convulsion fixed chronic。Controlling middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo。" book on Chinese herbal medicine is just ": " controlling acute infantile convulsion, Jiao, asthma agitation, terribly thirsty distension are closed in real expectorant excess-fire heap soil or fertilizer over and around the roots。" " book on Chinese herbal medicine converges and says ": " controls the frightened expectorant of infantile convulsion, tic of the limbs, adult's deficiency of vital energy interior-heat, the raw expectorant of heat stagnation。" " medicineization justice ": " cures mainly all apoplexy, acute infantile convulsion, infantile convulsion, wind syndrome of head, dizziness, and old god is slow-witted, and children's sends out and jerks, puerperal severe palpitation。"
Radix Saposhnikoviae: acrid, sweet, warm。Return bladder, liver, spleen channel。Inducing diaphoresis to dispel wind, removing dampness to relieve pain, only stem。For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus。Compendium of Material Medica: " wind as 36, goes part of the body cavity above the diaphragm housing the heart and lungs ailment said due to cold or exposure, the stagnant gas of the head, and meridians stay wet, all over the body pain all over the joints。Except wind dries elixir。" " medicine class on the analogy of natural things ": " control wind general。Eliminating the pathogens from the lung is real, dissipates stagnant gas in the head, except the part of the body cavity above the diaphragm housing the heart and lungs is evil。"
Herba Schizonepetae: pungent, tepor。Return lung, Liver Channel。Induce sweat scattered wind, rash, and disappear skin ulcer。For catching a cold, headache, measles, rubella, skin infection from the beginning of。" property of medicine opinion ": control aversion to wind harmful wind, the askew heresy of actinal surface, insensitive impediment all over, to have a guilty conscience and forget things, benefit power adds grain。The main poison that exorcises evil spirits, except labor, controls fourth and swells;Take one to hold and cut, with five liters of water, boil and take two liters, cold point two clothes, main promoting blood circulation, transmit the five internal organs deficiency gas, can diaphoresis, except cold wind;Smash again end and vinegar envelope poison is swollen。" feeding habits book on Chinese herbal medicine ": main blood consumptive disease due to wind gas is stopped up full, ridge pain, sweating due to debility, manages husband's beriberi, the tired pain of muscles and bones and YIN YANG toxin syndrome, cold headache, head rotation is dizzy, brothers' muscular contracture。
Hirudo: salty, bitter, flat;Slightly poisonous。Return Liver Channel。Removing blood stasis stimulates the menstrual flow, and removing blood stasis disappears。For blood stasis amenorrhea, abdominal mass mass in the abdomen, apoplectic hemiplegia, injury from falling down。" herbal classic ": " master closed by stagnant blood, blood stasis, the moon, and removing blood stasis abdominal mass is gathered, loss of fecundity, dredging water passages。"
The Radix Angelicae Dahuricae: pungent, temperature。Return stomach, large intestine, lung meridian。Induce sweat cold expelling, wind-expelling pain-stopping, declares clearing the nasal passage, moist pain relieving, detumescence and apocenosis。For headache due to common cold, supraorbital bone pain, watery nasal discharge of having a stuffy nose, allergic rhinitis, nasal sinusitis, toothache, leukorrhagia, skin infection swells and ache。" not Lu ": treat ailment said due to cold or exposure thirsty (thirsty for a long time or doubt make chronic diarrhea) for a long time, vomiting, fullness sensation in bilateral hypochondrium, wind pain dizziness, eye itching。" property of medicine opinion ": controlling trusted subordinate's blood twinge, exorcising, main woman's metrorrhagia and vomiting, improving eyesight, arresting lacrimation go out, treats married woman's drop blood, waist stomachache;Pus can be lost。" Japan hanako materia medica ": control conjunctival congestion bulbar conjunctiva polyp and tire patching leakage landing, broken stagnated blood, mend fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, evacuation of pus, desolation, scabies, pain relieving granulation promoting, go face defect scar。
Radix Angelicae Sinensis: sweet, acrid, warm。Return liver, the heart, spleen channel。Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation。For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation。Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow。For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down。" property of medicine opinion ": " preventing or arresting vomiting is inverse, asthenia cold and heat, broken stagnated blood, main woman's metrorrhagia, and lower the intestines and stomach is cold, mends various symptoms and signs of deficiency, and dysentery relieving is suffered from abdominal pain。Singly boil drink juice, control pyrexial malaria, main woman's lumbago with blood stasis, treat tooth pain unbearably painful。Suffer from people's cold caused by deficiency to add and use it。" " Japan hanako materia medica ": " controls a wind cutting, and all blood mend all labor, broken stagnant blood, supports fresh blood and main addiction。"
The Radix Paeoniae Alba: bitter, sour, is slightly cold。Return liver, spleen channel。Nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG。For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, dizziness of having a headache。" not Lu ": " clear and coherent blood vessels, in slow, dispelling malignant blood, expelling extravasated blood, anhydrate gas, profit bladder, intestine and small intestine, subduing inflammation, and row cold and heat time (controlling), attacked by pestiferous factors is suffered from abdominal pain, lumbago。" " property of medicine opinion ": " controls pathogen of the lung gas, abdominal pain, and vim and vigour are gathered, and logical a surname's internal organs gather around gas, controls evil pain deteriorated blood, and time main, disease bone heat, strong the five internal organs, the kidney invigorating gas, control trusted subordinate's heavily fortified point swollen, and married woman's blood closes obstructed, repercussive blood, can lose pus。"
Rhizoma Gastrodiae: sweet is flat。Return Liver Channel。Endogenous wind stopping relieving convulsion, suppressing liver-YANG, phoenix dredging collateral of dispelling。For infantile convulsion, epilepsy clonus, tetanus, dizziness of having a headache, hands and feet caused by paralysis, numb limbs and tense tendons, rheumatic arthralgia。" Kaibao Bencao ": main all rheumatism numbness, spasm of the limbs, children's's acute infantile convulsion, frightened gas, profit waist knee joint, strong biceps。" book on Chinese herbal medicine converges and says ": main wind syndrome of head, headache, dizzy empty rotation, the strong convulsion of epilepsy, suddenly, language has some setbacks extremity contraction, all apoplexy, wind-phlegm。
Ramulus Uncariae Cum Uncis: sweet is cool。Return liver, pericardium channel。Dispelling wind and relieving convulsion, heat clearing away suppressing the hyperactive liver。For liver-wind stirring up internally, infantile convulsion is twitched, hyperpyrexia convulsion, dysphoric cold, children's's night crying due to fright in infant, pre-eclampsia, dizziness of having a headache。" detailed outline ": " big number of people rotation is dizzy, suppressing liver-wind, and except heat in the heart, children's's infantile tic is suffered from abdominal pain, and sends out macule。" " book on Chinese herbal medicine is stated ": " controls paralysis due to windstroke, facial hemiparalysis, and all brothers' migratory arthralgia caused by wind pain, and podomere contraction is anxious。Controlling again the paralysis of many years ago gout, spasm of muscles and vessels is had a pain endlessly。"
Pheretima: salty, cold。Return liver, spleen, bladder warp。Heat clearing away is calmed the frightened, and dredging collateral is relievingd asthma, diuresis。For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema。
Radix Salviae Miltiorrhizae: bitter, is slightly cold。GUIXIN, Liver Channel。Blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle。For obstruction of qi in the chest and cardialgia, wrist abdomen hypochondriac pain, abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache。2, " herbal classic ": trusted subordinate's pathogen, borborygmus are faint, and as leaked water, cold and heat gather, and broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating。" not Lu ": nourishing blood, remove trusted subordinate's obstinate disease stagnation of QI, stiffness along the spinal column foot numbness, exorcising stays heat。Clothes profit people for a long time。
Rhizoma Curcumae Longae: pungent, bitter, temperature。Return spleen, Liver Channel。Removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia。Coercing twinge for breast, thoracic wall is pained, dysmenorrhea amenorrhea, abdominal mass, rheumatism shoulder arm pain, tumbling and swelling。" medical center bun is wanted ": control the anemofrigid-damp arthralgia of extremity。" modern Practical Chinese medicinal ": for fragrance stomachic, the disinfective action of favourable biliary tract and liver。For jaundice, the vexed pain of fullness in the chest painful abdominal mass。It is hemorrhage again, controls haematemesis, epistaxis, hematuria, and control haemorrhoids。Outer for abscess wound。
Lac caprae seu ovis: sweet, Xin Ping。Return lung, liver, spleen, large intestine channel。Relieve internal heat anticancer, benefiting qi and nourishing blood, detumescence and apocenosis。Controlling lung abscess, acute mastitis, acute appendicitis, toxic swelling, scrofula, throat moth, breast is few, leucorrhea。" detailed outline is picked up any lost article from the road ": " controlling toxic swelling scrofula, extracting juice and wine clothes, slag applies affected part。" Guangzhou army " conventional Chinese herbal medicine handbook ": " strengthening by means of tonics, lung moistening of eliminating the phlegm, promoting pus discharge and removing toxic substances。Control pulmonary abscess, mastitis, ulcerative carbuncle toxic swelling, venom。"
Radix Glycyrrhizae: sweet, flat。GUIXIN, lung, spleen, stomach warp。Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription。For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong。
Detailed description of the invention
Below, it is further described in conjunction with the example substantive distinguishing features to the present invention and advantage, but the invention is not limited in listed embodiment。
Embodiment 1
A kind of Poshangfeng mixture, including following component by weight: Gekko Swinhonis 25 weight portion, Scolopendra 25 weight portion, Scorpio 25 weight portion, Bombyx Batryticatus 25 weight portion, Periostracum Cicadae 20 weight portion, Herba Dendrobii 25 weight portion, Herba Hylothelephii Verticillati 25 weight portion, Arisaema Cum Bile 12 weight portion, Radix Saposhnikoviae 12 weight portion, Herba Schizonepetae 12 weight portion, Hirudo 6 weight portion, the Radix Angelicae Dahuricae 6 weight portion, Radix Angelicae Sinensis 6 weight portion, the Radix Paeoniae Alba 6 weight portion, Rhizoma Gastrodiae 6 weight portion, Ramulus Uncariae Cum Uncis 6 weight portion, Pheretima 6 weight portion, Radix Salviae Miltiorrhizae 6 weight portion, Rhizoma Curcumae Longae 6 weight portion, Lac caprae seu ovis 6 weight portion, Radix Glycyrrhizae 3 weight portion。
A kind of preparation method stating Poshangfeng mixture, comprises the following steps:
(1) weighing each medicine according to prescription, take Radix Angelicae Sinensis, Rhizoma Curcumae Longae, Rhizoma Gastrodiae 6 times of weight parts waters of addition, soak 2 hours, distillation extraction 1.5 hours, collect volatile oil, it is standby that addition beta-schardinger dextrin-makes clathrate, medicinal residues and debris;
(2) by step 1 Chinese medicine slag and Gekko Swinhonis, Scolopendra, Scorpio, Bombyx Batryticatus, Periostracum Cicadae, Herba Dendrobii, Herba Hylothelephii Verticillati, Arisaema Cum Bile, Radix Saposhnikoviae, Herba Schizonepetae, Hirudo, the Radix Angelicae Dahuricae, the Radix Paeoniae Alba, Ramulus Uncariae Cum Uncis, Pheretima, Radix Salviae Miltiorrhizae, Lac caprae seu ovis, Radix Glycyrrhizae merges, soak 2 hours, decoct twice, 2 hours first times, second time 1 hour, collecting decoction, filter, filtrate is concentrated into 500ml, add 2 times amount ethanol, stirring, stand 36 hours, filter, decompression filtrate recycling ethanol adds water to 1000ml, stand 36 hours, filter, add clathrate in step 1, add distilled water to adjust to 2000ml, stir evenly, stand 1 hour, filter, fill, put into high-temperature sterilization cabinet sterilizing, it is qualified to check, subpackage, obtain 100ml/ bottle, obtain。
Usage and dosage: one day 2-3 time, a 30-50ml;Or follow the doctor's advice。
Points for attention: be not taken by pregnant women。Taboo fish raw meat, pungent, all product of Herba Alii fistulosi Bulbus Allii;Avoid the foods such as raw and cold, greasy。
Embodiment 2
A kind of Poshangfeng mixture, including following component by weight: Gekko Swinhonis 25-30 weight portion, Scolopendra 30 weight portion, Scorpio 30 weight portion, Bombyx Batryticatus 30 weight portion, Periostracum Cicadae 30 weight portion, Herba Dendrobii 30 weight portion, Herba Hylothelephii Verticillati 30 weight portion, Arisaema Cum Bile 15 weight portion, Radix Saposhnikoviae 15 weight portion, Herba Schizonepetae 15 weight portion, Hirudo 8 weight portion, the Radix Angelicae Dahuricae 8 weight portion, Radix Angelicae Sinensis 8 weight portion, the Radix Paeoniae Alba 8 weight portion, Rhizoma Gastrodiae 8 weight portion, Ramulus Uncariae Cum Uncis 12 weight portion, Pheretima 8 weight portion, Radix Salviae Miltiorrhizae 8 weight portion, Rhizoma Curcumae Longae 8 weight portion, Lac caprae seu ovis 12 weight portion, Radix Glycyrrhizae 4 weight portion。
A kind of preparation method stating Poshangfeng mixture, comprises the following steps:
(1) weighing each medicine according to prescription, take Radix Angelicae Sinensis, Rhizoma Curcumae Longae, Rhizoma Gastrodiae 6-8 times of weight parts water of addition, soak 3 hours, distillation extraction 2 hours, collect volatile oil, it is standby that addition beta-schardinger dextrin-makes clathrate, medicinal residues and debris;
(2) by step 1 Chinese medicine slag and Gekko Swinhonis, Scolopendra, Scorpio, Bombyx Batryticatus, Periostracum Cicadae, Herba Dendrobii, Herba Hylothelephii Verticillati, Arisaema Cum Bile, Radix Saposhnikoviae, Herba Schizonepetae, Hirudo, the Radix Angelicae Dahuricae, the Radix Paeoniae Alba, Ramulus Uncariae Cum Uncis, Pheretima, Radix Salviae Miltiorrhizae, Lac caprae seu ovis, Radix Glycyrrhizae merges, soak 3 hours, decoct twice, 2.5 hours first times, second time 1.5 hours, collecting decoction, filter, filtrate is concentrated into 500ml, add 2 times amount ethanol, stirring, stand 36 hours, filter, decompression filtrate recycling ethanol adds water to 1000ml, stand 36 hours, filter, add clathrate in step 1, add distilled water to adjust to 2000ml, stir evenly, stand 1 hour, filter, fill, put into high-temperature sterilization cabinet sterilizing, it is qualified to check, subpackage, obtain 100ml/ bottle, obtain。
One day 2-3 time, a 30-50ml;Or follow the doctor's advice。
Points for attention: be not taken by pregnant women。Taboo fish raw meat, pungent, all product of Herba Alii fistulosi Bulbus Allii;Avoid the foods such as raw and cold, greasy。
Fang Xie:
The tetanic origin cause of formation, is that from sore, intrusion forms because of pathogenic wind toxic。Pathogenic wind toxic invades passages through which vital energy circulates so that obstructed circulation of nutrient QI and defensive QI, the turbid retardance of expectorant, in addition evil incoming in, exogenous wind priming liver-wind, therefore see that mandibular joint is urgent, mouth scoops up lockjaw, orthotonus, opisthotonus, contracting tongue of very then gritting one's teeth;Stringy and tense pulse, be also pneumatic as。Therefore control suitable dispelling pathogenic wind and eliminating phlegm, relieving convulsion of surely jerking。In side, Gekko Swinhonis, Scolopendra, Scorpio, Bombyx Batryticatus, Periostracum Cicadae gather dispelling pathogenic wind and eliminating phlegm altogether, and analgesic therapy relieving convulsion is monarch drug;Five pungent temperature, all kind dispelling pathogenic wind and eliminating phlegm, relieving convulsion of surely jerking, for controlling the key medicine of tetanus。Gekko Swinhonis expelling wind for relieving convulsion;Detoxicating and resolving stagnation of pathogens, Scolopendra endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, Scorpio endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, the effects such as Periostracum Cicadae convulsion with spasms is principal agent altogether, plays endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain;Herba Dendrobii, Herba Hylothelephii Verticillati, Arisaema Cum Bile, Radix Saposhnikoviae, Herba Schizonepetae, Hirudo, the Radix Angelicae Dahuricae, Pheretima assist monarch drug to evacuate the ailment said due to cold or exposure in meridians, lead heresy to go out, wherein Arisaema Cum Bile, Herba Schizonepetae, Radix Saposhnikoviae can dissipate the wind of the sun, Hirudo, Pheretima, the positive bright wind of angelica dahurica powder, Herba Dendrobii, Herba Hylothelephii Verticillati improve immunity, close and with it, are total to principal drug assistance and evacuate the ailment said due to cold or exposure in meridians, for ministerial drug Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis principal drug assistance relieving spasm by calming endogenous wind, it is adjuvant drug;Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Rhizoma Curcumae Longae, Lac caprae seu ovis, Radix Glycyrrhizae dredging the meridian, qi and blood circulation promotion are for making medicine。Taking a broad view of full side's medication, to evacuate, the power dispeled the wind is relatively strong, for tetanus, has wind to dissipate fixed merit of jerking。
Clinical data:
Treating tetanic Chinese patent medicine at present and have seldom, mainly based on provisional prescription, Traditional Chinese medicine decocting, the time is longer, bothersome effort, and can not disposable produce in enormous quantities, inconvenient to carry。Doctor trained in Western medicine mainly has tetanus antitoxin, produces untoward reaction。My institute is theoretical according to differential diagnosis in tcm, and in conjunction with modern medicine study, my institute carries out screening in conjunction with history proved recipe handed down from one's ancestors, add and subtract。Good effect is played for tetanus treatment。It can be seen that this preparation curative effect is high studying from clinical practice prescription, effective, the course for the treatment of of shortening, make extensive patients resume work in advance, both alleviated physical pain, added economic benefit。
Clinical data:
This group case is all tetanus patient, according to patient's different situations, is divided into a treatment group, a matched group, i.e. treatment group takes tetanus mixture 100 example orally, compares tetanus antitoxin 100 example。
In 200 example patients, male 137 examples, female 63 example, the age between 10-55,29.5 years old mean age。
The above is only the preferred embodiment of the present invention; it should be pointed out that, for those skilled in the art, under the premise without departing from the principles of the invention; can also making some improvements and modifications, these improvements and modifications also should be regarded as protection scope of the present invention。

Claims (2)

1. a Poshangfeng mixture, it is characterized in that, including following component by weight: Gekko Swinhonis 25-30 weight portion, Scolopendra 25-30 weight portion, Scorpio 25-30 weight portion, Bombyx Batryticatus 25-30 weight portion, Periostracum Cicadae 20-30 weight portion, Herba Dendrobii 25-30 weight portion, Herba Hylothelephii Verticillati 25-30 weight portion, Arisaema Cum Bile 12-15 weight portion, Radix Saposhnikoviae 12-15 weight portion, Herba Schizonepetae 12-15 weight portion, Hirudo 6-8 weight portion, Radix Angelicae Dahuricae 6-8 weight portion, Radix Angelicae Sinensis 6-8 weight portion, Radix Paeoniae Alba 6-8 weight portion, Rhizoma Gastrodiae 6-8 weight portion, Ramulus Uncariae Cum Uncis 6-12 weight portion, Pheretima 6-8 weight portion, Radix Salviae Miltiorrhizae 6-8 weight portion, Rhizoma Curcumae Longae 6-8 weight portion, Lac caprae seu ovis 6-12 weight portion, Radix Glycyrrhizae 3-4 weight portion。
2. the preparation method of Poshangfeng mixture described in a claim 1, it is characterised in that comprise the following steps:
(1) weighing each medicine according to prescription, take Radix Angelicae Sinensis, Rhizoma Curcumae Longae, Rhizoma Gastrodiae 6-8 times of weight parts water of addition, soak 2-3 hour, distillation extraction 1.5-2 hour, collect volatile oil, it is standby that addition beta-schardinger dextrin-makes clathrate, medicinal residues and debris;
(2) by step 1 Chinese medicine slag and Gekko Swinhonis, Scolopendra, Scorpio, Bombyx Batryticatus, Periostracum Cicadae, Herba Dendrobii, Herba Hylothelephii Verticillati, Arisaema Cum Bile, Radix Saposhnikoviae, Herba Schizonepetae, Hirudo, the Radix Angelicae Dahuricae, the Radix Paeoniae Alba, Ramulus Uncariae Cum Uncis, Pheretima, Radix Salviae Miltiorrhizae, Lac caprae seu ovis, Radix Glycyrrhizae merges, soak 2-3 hour, decoct twice, 2-2.5 hour first time, second time 1-1.5 hour, collecting decoction, filter, filtrate is concentrated into 500ml, add 2 times amount ethanol, stirring, stand 36 hours, filter, decompression filtrate recycling ethanol adds water to 1000ml, stand 36 hours, filter, add clathrate in step 1, add distilled water to adjust to 2000ml, stir evenly, stand 1 hour, filter, fill, put into high-temperature sterilization cabinet sterilizing, it is qualified to check, subpackage, obtain 100ml/ bottle, obtain。
CN201610092924.8A 2016-02-20 2016-02-20 Tetanus mixture and preparation method thereof Pending CN105688038A (en)

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Application publication date: 20160622