CN110151893A - A kind of analgesic ointment and preparation method thereof - Google Patents

A kind of analgesic ointment and preparation method thereof Download PDF

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CN110151893A
CN110151893A CN201910463424.4A CN201910463424A CN110151893A CN 110151893 A CN110151893 A CN 110151893A CN 201910463424 A CN201910463424 A CN 201910463424A CN 110151893 A CN110151893 A CN 110151893A
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camphor
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paris polyphylla
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夏清山
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
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    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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Abstract

A kind of analgesic ointment, is prepared from the following raw materials in parts by weight: raw cape jasmine 15-25 parts, 16-26 parts of Paris polyphylla, and 6-16 parts of konjaku, 3-13 parts of asarum, 3-7 parts of camphor, 3-7 parts of menthol, 25-35 parts of medical ventolin, 95% 2-4 parts of ethyl alcohol, 14-24 parts of water;Preparation method: first will be by raw cape jasmine, Paris polyphylla, konjaku, asarum, camphor pulverizes after processing;By camphor, menthol mixed grinding in a reservoir, then it is added after 95% ethyl alcohol mixes and removes impurity with strainer;Paris polyphylla is poured into medical ventolin, is stirred evenly;Then by water, konjaku flour, raw cape jasmine and the mixing of above-mentioned solution are to get ointment.It is quick, it can eradicate, the balm of the easy muscle blood-activating bone-strengthening anti-inflammatory of Small side effects.

Description

A kind of analgesic ointment and preparation method thereof
Technical field
The present invention relates to drug field, it is related specifically to a kind of analgesic ointment and preparation method thereof.
Background technique
Chinese medicine thinks: qi being the governor of blood, blood being the material foundation of QI, and then blood arrives gas row, and blood is such as passed through to the then whole body, and yin-yang reconciles, body Body health.If limbs injured, congestion blood block, QI-blood circulation is unsmooth, then: " not general rule pain, general rule is not swollen ".Treatment is with " promoting blood circulationization Based on the stasis of blood, promoting qi circulation and relieving pain ", extravasated blood go then new blood it is raw, qi and blood and suitable, " no pain by smooth breath ".
Bone is frustrated in traumatic injury, red and swollen heat pain, the injury of the tissues, and new and old silt is suffered from, numbness mouth pyogenic infections, snakebite and bugbite, the clinics such as all kinds of inflammation Upper common disease, these diseases bring very big pain to many patients.Medication effect is unobvious at present, and is easy to produce resistance to Pharmacological property, it is difficult to prove effective;Operative treatment risk is big, costly;Traction, massage, acupuncture and moxibustion therapy can only treat the symptoms to effect a permanent cure;Western medicine is controlled Treatment side effect is big, and the state of an illness is easily repeatedly.Accordingly, it is desirable to a kind of balm of eutherapeutic easy muscle blood-activating bone-strengthening anti-inflammatory.
Summary of the invention
The purpose of the present invention is overcoming to work in existing common treatment method slowly, hardly possible radical cure, the big problem of side effect provides one Kind is quick, can eradicate, the balm of the easy muscle blood-activating bone-strengthening anti-inflammatory of Small side effects.
In order to achieve the above object, technical solution of the invention is as follows:
A kind of analgesic ointment, is prepared from the following raw materials in parts by weight: raw cape jasmine 15-25 parts, 16-26 parts of Paris polyphylla, and konjaku 6-16 parts, 3-13 parts of asarum, 3-7 parts of camphor, 3-7 parts of menthol, 25-35 parts of medical ventolin, 95% 2-4 parts of ethyl alcohol, water 14- 24 parts.
A kind of analgesic ointment is prepared from the following raw materials in parts by weight: 20 parts of raw cape jasmine, and 21 parts of Paris polyphylla, 11 parts of konjaku, carefully Pungent 8 parts, 5 parts of camphor, 5 parts of menthol, 30 parts of medical ventolin, 95% 3 parts of ethyl alcohol, 19 parts of water.
A kind of preparation method relieving pain ointment, comprising the following steps:
(1) by raw cape jasmine, Paris polyphylla, konjaku, asarum, camphor, which processes, to be pulverized;
(2) above-mentioned parts by weight are pressed, take just treated raw material, menthol, 95% ethyl alcohol and water respectively;By camphor powder, Then menthol mixed grinding in a reservoir is added after 95% ethyl alcohol mixes and is filtered to remove impurity;Paris polyphylla powder is poured into medical In vaseline, stir evenly;Konjaku flour is poured into water, quickly stirring keeps konjaku flour completely soluble;
(3) it will be mixed with the mixed liquor of camphor, menthol, 95% ethyl alcohol, the medical ventolin of Paris polyphylla powder is mixed with, is mixed with konjaku The aqueous solution of powder, asarum powder and raw gardenia powder are poured into same container, are sufficiently stirred evenly to get analgesic ointment.
Raw cape jasmine concocting method in the step (1): weeding out grey bits, pick impurity, then does at a temperature of 60 DEG C -80 DEG C It is 1-3 hours dry, it takes out and pulverizes, gardenia powder must be given birth to by crossing 80 meshes.
Paris polyphylla concocting method in the step (1): removing impurity, cleans, moisturizes, and shave dries, then 60 DEG C- Dry 1-3 hours at a temperature of 80 DEG C, takes out and pulverized 80 meshes and obtain Paris polyphylla powder.
Konjaku concocting method in the step (1): removing impurity, cleans, moisturizes, cut sheet, then 60 DEG C of -80 DEG C of temperature It degree lower dry 1-3 hours, takes out and pulverized 80 meshes and obtain konjaku flour.
Asarum concocting method in the step (1): removing impurity, sprays clear water, slightly moistens, and dissection is dried in the shade, and then 40 It is 1-3 hours dry at a temperature of DEG C -60 DEG C, it takes out and pulverized 80 meshes and obtain asarum powder.
Camphor concocting method in the step (1): by camphor booth on clean paper, impurity is removed, absorbs oil residues Rouge and moisture, pulverization.
Medical ventolin described in the step (2) is needed during being added to Paris polyphylla powder in semi-fluid shape.
A kind of application of the analgesic ointment in the drug of preparation treatment diabetes.
Medication principle:
Raw cape jasmine also known as Yellow Fructus Gardeniae, mountain Cape jasmine etc. are the fruit of madder wort mountain Cape jasmine.The major functions: Vexed, irascibility mesh Red, headache, stranguria, bloody flux hematuria, aphthae, sore swollen toxin, sprains swelling and pain at damp and hot yellow infantile malnutrition due to digestive disturbances or intestinalparasites.
Paris polyphylla is the dry rhizome of liliaceous plant Yunnan Rhizoma Paridis or paris polyphylla.Its bitter, cold nature;It is slightly poisonous. There is the effect of clearing heat and detoxicating, cool liver is calmed the frightened, is usually used in furunculosis carbuncle swells, abscess of throat, snakebite and bugbite, the pain of injury caused by falling and tumbling, convulsion.
Asarum belongs to Aristolochiales, Aristolochiaceae perennial grass.There is a wind-dispelling, cold dispelling, row water, have one's ideas straightened out and other effects.It is usually used in wind Cold head pain, nasosinusitis, dentalgia, sip and cough, rheumatic arthralgia etc..Asarum can outer dispersing wind and cold and in but cold sensation of the genitalia, while relieve pain, Antibechic effect is preferable.
Camphor is Lauraceae cinnamon.With orifice opening, qi stagnation removing keeps away foul, the effect of desinsection is antipruritic, swelling and pain relieving. It is dizzy to cure mainly pyreticosis mind, middle evil is dampinged off, acute filthy disease vomiting and diarrhoea abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, scabies stubborn dermatitis, the favus of the scalp, pernio, ulcer on the shank, scald, Injuries from falls as well, toothache, wind-fire red eye.
Menthol, Chinese patent drug name.A kind of cyclic alcohol of saturation obtained in peppermint oil forms.With dispelling wind, heat-clearing, solution Effect of poison.It is mainly used for treating the diseases such as headache and hot eyes, affection of exogenous wind-heat, pharynx tooth swelling and pain, skin pruritus.
Konjaku, can activating microcirculation and removing stasis medicinal, removing toxicity for detumescence, wide intestines defaecation, resolving phlegm and softening hard masses;Cure mainly blood pressure lowering, hypoglycemic, scrofula phlegm The symptoms such as core, the damage stasis of blood swollen, constipation abdominal pain, abscess of throat, swelling and aching of gum.
Character: this product is sepia ointment;Gas is special, and touching has refrigerant sense.
Usage: taking medicine appropriate, be applied in film paper, and less serious case or painful area list one can directly stick affected part.The state of an illness compared with Weight or affected part are more, in addition to selecting main affected part to stick, stick on middle elixir field (navel) or post and close corresponding acupuncture point, then better effect. It is removed after sticking 8 hours daily, cleans skin, the primary effective or recovery from illness of less serious case, severe, more person's second day dressing continues to paste It applies.
Remarks: one, externally applied drug, mouth, not apply intranasally at eye.If occurring green, color purple after two, applying, without frightened, Lock-out after a few days.
Taboo: pregnant woman is used with caution.
Storage: at cool place is dry.
The major functions: one, traumatic injury, red and swollen heat pain, that applies has the benefits of cooling and activating blood, swelling and pain relieving.Two, bone is frustrated in the injury of the tissues, newly Old silt is suffered from, and deposited energy dredging collateral is active, and scattered silt analgesic promotes sclerotin healing.Three, numbness mouth swelling and pain poison, snakebite and bugbite, less serious case can detoxify It dissipates, has become purulence or fester, disease severe one, energy detoxification mentions purulence, and myogenic is put on flesh, and promotes healing.Four, cholecystitis, pancreatitis, appendix The acute diseases such as inflammation, enterospasm, acute nephritis, urinary system infection contamination spread on lesion corresponding topical skin, there is anti-inflammatory, spasmolysis, analgesic Effect.Five, it is applied to various cancers, tumour, there is softening hard masses, the knot that disappears, anti-inflammatory and apparent analgesic effect.Six, to four limbs open section and Pain in back and loin, neuralgia (head nerves, intercostal nerve, spinal nerves etc.), women's blockage of menstruation, the diseases such as premenstrual abdominal pain apply it, There are clearing and activating the channels and collaterals, anti-inflammatory analgetic curative effect.Seven, blood glucose can be reduced, glycosuria patient can paste lower elixir field (under navel at four horizontal fingers), can It reduces blood glucose and mitigates or cure complication.
Through the above technical solutions, beneficial effects of the present invention:
1, raw cape jasmine used in the present invention, Paris polyphylla, asarum, camphor, konjaku have good treatment to strain swelling and pain Effect, mitigate sprain swelling and pain bring pain, while can activating microcirculation and removing stasis medicinal, have certain effect to snakebite and bugbite.In addition peppermint Anti-inflammatory, spasmolysis, analgesic effect are played in the combination of brain, alleviate and stick bring fiber crops on skin for a long time and the symptoms such as itch.
2, medical ventolin is employed herein, on the one hand allows medicine in paste convenient for sticking, another aspect vaseline energy Skin moisture is enough kept, avoids falling off and having dry skin caused by sticking for a long time.
3, the preparation method of traditional Chinese medicinal ointment of the present invention is simple, easy to operate, is suitable for popularization and application.Medicinal material adds progress stage by stage Preparation, can retain to the greatest extent and improve drug effect, guarantee the therapeutic effect of drug.
4, ointment of the invention can also play certain therapeutic effect to diabetic.Modern Chinese medicine belongs to diabetes Range more wide " the spleen-warm syndrome " " disappear illness " scope, Paris polyphylla in the present invention, camphor, menthol all has heat-clearing, promotion of blood circulation Effect, alleviates damp and hot symptom in diabetes, and konjaku has hypoglycemic effect, can play one to diabetic after combining Determine therapeutic effect.
Specific embodiment
The present invention is further explained in the light of specific embodiments.
A kind of analgesic ointment of the invention, is prepared from the following raw materials in parts by weight: raw cape jasmine 15-25 parts, Paris polyphylla 16-26 Part, 6-16 parts of konjaku, 3-13 parts of asarum, 3-7 parts of camphor, 3-7 parts of menthol, 25-35 parts of medical ventolin, 95% ethyl alcohol 2-4 Part, 14-24 parts of water.
A kind of preparation method relieving pain ointment, comprising the following steps:
(1) by raw cape jasmine, Paris polyphylla, konjaku, asarum, camphor pulverizes after processing;
(2) above-mentioned parts by weight are pressed, take just treated raw material, menthol, 95% ethyl alcohol and water respectively;By camphor powder, Then menthol mixed grinding in a reservoir is added after 95% ethyl alcohol mixes and is filtered to remove impurity;Paris polyphylla powder is poured into medical In vaseline, stir evenly;Konjaku flour is poured into water, quickly stirring keeps konjaku flour completely soluble;
(3) it will be mixed with the mixed liquor of camphor, menthol, 95% ethyl alcohol, the medical ventolin of Paris polyphylla powder is mixed with, is mixed with konjaku Powder obtains aqueous solution, and asarum powder and raw gardenia powder are poured into same container, sufficiently stirred evenly to get analgesic ointment.
Raw cape jasmine concocting method in the step (1): weeding out grey bits, pick impurity, then does at a temperature of 60 DEG C -80 DEG C It is 1-3 hours dry, it takes out and pulverizes, gardenia powder must be given birth to by crossing 80 meshes.
Paris polyphylla concocting method in the step (1): removing impurity, cleans, moisturizes, and shave dries, then 60 DEG C- Dry 1-3 hours at a temperature of 80 DEG C, takes out and pulverized 80 meshes and obtain Paris polyphylla powder.
Konjaku concocting method in the step (1): removing impurity, cleans, moisturizes, cut sheet, then 60 DEG C of -80 DEG C of temperature It degree lower dry 1-3 hours, takes out and pulverized 80 meshes and obtain konjaku flour.
Asarum concocting method in the step (1): removing impurity, sprays clear water, slightly moistens, and dissection is dried in the shade, and then 40 It is 1-3 hours dry at a temperature of DEG C -60 DEG C, it takes out and pulverized 80 meshes and obtain asarum powder.
Camphor concocting method in the step (1): by camphor booth on clean paper, impurity is removed, absorbs oil residues Rouge and moisture, pulverization.
Medical ventolin described in the step (2) is needed during being added to Paris polyphylla powder in semi-fluid shape.
Embodiment 1:
Raw material preparation process: weeding out grey bits for raw cape jasmine, pick impurity, then 1 hour dry at a temperature of 80 DEG C, takes out stone roller Broken 80 mesh of mistake;Paris polyphylla is removed into impurity, is cleaned, is moisturized, cut sheet, it is then 1 hour dry at a temperature of 80 DEG C, it takes out and pulverized 80 meshes;Konjaku concocting method: removing impurity, cleans, moisturizes, cut sheet, then 1 hour dry at a temperature of 80 DEG C, takes out stone roller Broken 80 mesh of mistake;Asarum is removed into impurity, clear water is sprayed, slightly moistens, dissection is dried in the shade, and it is then 1 hour dry at a temperature of 60 DEG C, it takes 80 meshes were pulverized out;By camphor booth on clean paper, impurity is removed, absorbs residual grease and moisture, pulverization.
Raw material is weighed by following parts by weight: 20 parts of raw cape jasmine, 21 parts of Paris polyphylla, 11 parts of konjaku, 8 parts of asarum, 5 parts of camphor, 5 parts of menthol, 30 parts of medical ventolin, 95% 3 parts of ethyl alcohol, 19 parts of water.
By camphor, menthol mixed grinding in a reservoir, then it is added after 95% ethyl alcohol mixes and is filtered to remove impurity;It will Paris polyphylla powder pours into after heating in the medical ventolin of semi-fluid shape, stirs evenly;Konjaku flour is poured into water, quickly stirring makes evil spirit Taro powder, which is dissolved in after water, will be mixed with camphor, menthol, the mixed liquor of ethyl alcohol and raw gardenia powder, asarum powder and pour into wherein, add mixed There is the medical ventolin of Paris polyphylla powder, sufficiently stir evenly, obtain a kind of sepia ointment, touching has refrigerant sense.
Embodiment 2:
Raw material preparation process: weeding out grey bits for raw cape jasmine, pick impurity, then 3 hours dry at a temperature of 60 DEG C, takes out stone roller Broken 80 mesh of mistake;Paris polyphylla is removed into impurity, is cleaned, is moisturized, cut sheet, it is then 3 hours dry at a temperature of 60 DEG C, it takes out and pulverized 80 meshes;Konjaku concocting method: removing impurity, cleans, moisturizes, cut sheet, then 3 hours dry at a temperature of 60 DEG C, takes out stone roller Broken 80 mesh of mistake;Asarum is removed into impurity, clear water is sprayed, slightly moistens, dissection is dried in the shade, and it is then 3 hours dry at a temperature of 40 DEG C, it takes 80 meshes were pulverized out;By camphor booth on clean paper, impurity is removed, absorbs residual grease and moisture, pulverization.
Raw material is weighed by following parts by weight: 25 parts of raw cape jasmine, 16 parts of Paris polyphylla, 6 parts of konjaku, 13 parts of asarum, 3 parts of camphor, 3 parts of menthol, 25 parts of medical ventolin, 95% 2 parts of ethyl alcohol, 24 parts of water.
By camphor, menthol mixed grinding in a reservoir, then it is added after 95% ethyl alcohol mixes and is filtered to remove impurity;It will Paris polyphylla powder pours into after heating in the medical ventolin of semi-fluid shape, stirs evenly;Konjaku flour is poured into water, quickly stirring makes evil spirit Taro powder, which is dissolved in after water, will be mixed with camphor, menthol, the mixed liquor of ethyl alcohol and raw gardenia powder, asarum powder and pour into wherein, add mixed There is the medical ventolin of Paris polyphylla powder, sufficiently stir evenly, obtain a kind of sepia ointment, touching has refrigerant sense.
Embodiment 3:
Raw material preparation process: weeding out grey bits for raw cape jasmine, pick impurity, then 2 hours dry at a temperature of 70 DEG C, takes out stone roller Broken 80 mesh of mistake;Paris polyphylla is removed into impurity, is cleaned, is moisturized, cut sheet, it is then 2 hours dry at a temperature of 70 DEG C, it takes out and pulverized 80 meshes;Konjaku concocting method: removing impurity, cleans, moisturizes, cut sheet, then 2 hours dry at a temperature of 70 DEG C, takes out stone roller Broken 80 mesh of mistake;Asarum is removed into impurity, clear water is sprayed, slightly moistens, dissection is dried in the shade, and it is then 2 hours dry at a temperature of 50 DEG C, it takes 80 meshes were pulverized out;By camphor booth on clean paper, impurity is removed, absorbs residual grease and moisture, pulverization.
Raw material is weighed by following parts by weight: 15 parts of raw cape jasmine, 26 parts of Paris polyphylla, 16 parts of konjaku, 3 parts of asarum, 7 parts of camphor, 7 parts of menthol, 35 parts of medical ventolin, 95% 4 parts of ethyl alcohol, 14 parts of water.
By camphor, menthol mixed grinding in a reservoir, then it is added after 95% ethyl alcohol mixes and is filtered to remove impurity;It will Paris polyphylla powder pours into after heating in the medical ventolin of semi-fluid shape, stirs evenly;Konjaku flour is poured into water, quickly stirring makes evil spirit Taro powder, which is dissolved in after water, will be mixed with camphor, menthol, the mixed liquor of ethyl alcohol and raw gardenia powder, asarum powder and pour into wherein, add mixed There is the medical ventolin of Paris polyphylla powder, sufficiently stir evenly, obtain a kind of sepia ointment, touching has refrigerant sense.
One, toxicity test:
1, acute toxicity testing:
Cavy 60 are taken, random point three groups, depilation, every group of difference external application embodiment 1, embodiment 2, made from embodiment 3 It relieves pain ointment to test, continuous use 15 days;As a result: cavy is complete and the big small dose group of damaged skin none animal dead, respectively The activity of group cavy, stool and urine, mental status etc. is normal, and the reaction such as damaged skin no inflammation, oozing of blood is not also found apparent Whole body toxicity illustrates that patch application prepared by the present invention is safe.
2, skin irritation test:
Analgesic ointment is to cavy intact skin without obvious irritation prepared by the present invention;To damaged skin irritation compared with Small, part does not occur the skin irritatins phenomenon such as erythema, infection or redness.
3, allergic experiment:
Take cavy 30, half male and half female, random point three groups, every group of difference external application embodiment 1, embodiment 2, embodiment 3 makes The analgesic ointment experiment obtained;As a result: using after analgesic ointment prepared by the present invention, the hair color of cavy, state of mind etc. is different It often occurs as illustrating that patch prepared by the present invention does not generate allergic phenomena.
4, long term toxicity test:
Cavy 60 are taken, random point three groups, depilation, every group of difference external application embodiment 1, embodiment 2, made from embodiment 3 It relieves pain ointment to test, continuous use 60 days;As a result: the present invention relieves pain ointment to the hair of cavy, behavior, stool and urine, weight, dirty The indexs such as the amount of thinking highly of, blood picture, hepatic and renal function, blood glucose, blood lipid all have no significant effect.Histological examination shows medication 60 days and stops After medicine 2 weeks, cavy internal organs are without obvious Histological change.During medication and be discontinued after the performance without exception of each group cavy, behavior Vivaciously, it ingests normal, stool and urine is without exception.Illustrate analgesic ointment prepared by the present invention without long term toxicity, application is safe.
Two, clinical application:
Traumatic injury, the clinical application of red and swollen heat pain
The present invention can treat traumatic injury, numbness mouth swelling and pain, once for treating and observing 150 traumatic injuries, red and swollen heat pain Patient.By above-mentioned ready 3 kinds of experimental example samples, it is respectively used to traumatic injury, the patient with sympotoms such as numbness mouth swelling and pain (male 102, Female 48, average age 58 years old).As a result see Table 1 for details, wherein curing: affected part swelling, the symptoms such as pain disappear, and life is normal;Nothing Effect: symptom is unchanged.
1 clinical application effect table of table
Embodiment It cures (%) (%) in vain
Embodiment 1 (71 people) 97 3
Embodiment 2 (42 people) 98 2
Embodiment 3 (37 people) 95 5
Case 1:
Mr. Wang, male, 40 years old, left foot was sprained when getting out of a predicament or an embarrassing situation, swelling pain, was walked tired right, patch is used ointment 1 time of the present invention, complete Totally disappeared it is swollen, continue patch with 1 time, pain substantially eliminates, walk freely.
Case 2:
Perhaps certain, male, and 44 years old, right leg red and swollen heat pain generated heat 3 days with body, was diagnosed as erysipelas, pastes medicine produced by the present invention It lies up in affected part, and by doctor's advice within cream 3 days, lifting affected limb, patient's right leg heat pain and body heat symptom-complex shape disappear, and patient's reaction is good It is good, it is without side-effects.
The injury of the tissues, the clinical application of fracture
The present invention can treat the injury of the tissues, fracture, once for treating and observing 98 injury of the tissues, fracture patient.It is ready to above-mentioned 3 kinds of experimental example samples, be respectively used to the injury of the tissues and frustrate bone, the patient with sympotoms such as fracture bone split (male 50, female 48, average age 43 Year).As a result see Table 2 for details.Wherein cure: fracture site healing is good, and life is normal;Invalid: symptom is unchanged.
2 clinical application effect table of table
Embodiment It cures (%) (%) in vain
Embodiment 1 (40 people) 97.5 2.5
Embodiment 2 (32 people) 97 3
Embodiment 3 (26 people) 93 7
Case 3:
Zhang, female, 35 years old, fracture of lower arm, with ointment produced by the present invention 2 weeks in affected part, arm pain mitigated, continues to paste patch With 2 weeks, basic rehabilitation, activity was normally.
Arthralgic clinical application
The present invention can treat arthralgia, once for treating and observing 60 arthralgia patients.By above-mentioned ready 3 kinds of realities A sample is tested, the patient with sympotoms such as arthralgia (male 20, female 40, average age 55 years old) is respectively used to.As a result see Table 3 for details.Its In it is effective: the symptoms such as painful swelling of joints disappear, and life is normal;Effective: pain relief, affected part joint can do simple activities, invalid: disease Shape is unchanged.
3 clinical application effect table of table
Embodiment Effective (%) Effectively (%) (%) in vain
Embodiment 1 (20 people) 40 50 10
Embodiment 2 (20 people) 35 55 10
Embodiment 3 (20 people) 35 60 5
Case 4:
Hu, female 42 years old, suffer from rheumatoid rheumatoid arthritis, and limb painful swelling of joints is stiff, and double fingers deformeds can not close up, Finger can not work normally, and for patch with ointment produced by the present invention 1 week in affected part, symptom is substantially reduced, continue to paste with 2 weeks, finger It can be fully come together as normal person.
The clinical treatment of inflammation
The present invention can treat inflammation, once for treating and observing 200 inflammatory patients.By above-mentioned ready 3 kinds of experiments Example sample is respectively used to the critical patients such as cholecystitis, pancreatitis, ecphyaditis, enterospasm, acute nephritis, urinary system infection contamination (male 156, female 44, average age 57 years old).As a result see Table 4 for details, wherein effective: inflammation disappears, and other malaise symptoms disappear;Have Effect: inflammation is alleviated, and other malaise symptoms are alleviated;Invalid: symptom is unchanged.
4 clinical application effect table of table
Embodiment Effective (%) Effectively (%) (%) in vain
Embodiment 1 (100 people) 70 23 7
Embodiment 2 (50 people) 77 15 8
Embodiment 3 (50 people) 75 14 11
Case 5:
Chen, female 60 years old, suffer from cholecystitis and calculus 3 years, patch is with ointment produced by the present invention 3 weeks in affected part external skin Skin, pain relief, inflammation are eliminated, and calculi in vivo is discharged in cooperation lithagogue treatment.
The clinical treatment of cancer
Energy treating cancer of the present invention, once for treating and observing 60 cancer patients.By above-mentioned ready 3 kinds of experimental examples Sample is respectively used to the patient with sympotoms such as cancer (male 30, female 30, average age 56 years old).As a result see Table 5 for details.It is wherein effective: Foci disappearance, no recurrence;Effective: lesion reduces, and the complication such as pain disappear, and life is as usual;Invalid: symptom is without obvious after treatment Improve.
5 clinical application effect table of table
Embodiment Effective (%) Effectively (%) (%) in vain
Embodiment 1 (20 people) 25 65 10
Embodiment 2 (20 people) 25 65 10
Embodiment 3 (20 people) 30 60 5
Case 6:
Slowly certain, male, 55 years old, suffers from primary laryngocarcinoma, and later six months disease relapse of performing the operation for the first time is pasted with produced by the present invention In affected part, pain relief continued patch with 2 months, and symptom is alleviated substantially, can normally live within ointment 1 month.
The clinical application of diabetes
The present invention treats the traditional Chinese herb medicine of diabetes, once for treating and observing 86 diabetics.By above-mentioned preparation 3 kinds of good experimental example samples are respectively used to hyperglycemia with the tired patient with sympotoms such as powerless, weakness of the spleen and the stomach of more drinks, diuresis, syntexis, body (male 50, female 26, average age 52 years old).As a result see Table 6 for details, wherein effective: symptom disappears substantially after treatment, fasting blood-glucose < 7.2mmol/L, postprandial 2 hours blood glucose
< 8.3mmol/L, effectively: symptom is obviously improved after treatment, fasting blood-glucose < 8.3mmol/L, and postprandial 2 hours blood glucose < 10.0mmol/L, invalid: symptom is not improved after treatment, and blood glucose decline is not up to These parameters.
6 clinical application effect table of table
Embodiment Effective (%) Effectively (%) (%) in vain
Embodiment 1 (30 people) 43 43 14
Embodiment 2 (28 people) 43 36 21
Embodiment 3 (28 people) 50 32 18
Case 7:
Field, female 50 years old, suffer from diabetes, only take melbine, chemically examine fasting blood-glucose 12.5mmol/L, postprandial 2 is small When blood glucose 14mmol/L, patch with ointment produced by the present invention 1 week in lower elixir field (under navel at four horizontal fingers), after a week, chemically examine empty stomach Blood glucose 7.6mmol/L, postprandial 2 hours blood glucose 9mmol/L continue to paste this ointment, and blood glucose target is normal.

Claims (10)

1. a kind of analgesic ointment, it is characterised in that: be prepared from the following raw materials in parts by weight: raw cape jasmine 15-25 parts, Paris polyphylla 16- 26 parts, 6-16 parts of konjaku, 3-13 parts of asarum, 3-7 parts of camphor, 3-7 parts of menthol, 25-35 parts of medical ventolin, 95% ethyl alcohol 2-4 Part, 14-24 parts of water.
2. a kind of analgesic ointment according to claim 1, it is characterised in that: be prepared from the following raw materials in parts by weight: raw 20 parts of cape jasmine, 21 parts of Paris polyphylla, 11 parts of konjaku, 8 parts of asarum, 5 parts of camphor, 5 parts of menthol, 30 parts of medical ventolin, 95% ethyl alcohol 3 Part, 19 parts of water.
3. a kind of preparation method of analgesic ointment described in any one of -2 according to claim 1, it is characterised in that including following Step:
(1) by raw cape jasmine, Paris polyphylla, konjaku, asarum, camphor, which processes, to be pulverized;
(2) above-mentioned parts by weight are pressed, take just treated raw material, menthol, 95% ethyl alcohol and water respectively;By camphor powder, menthol Then mixed grinding in a reservoir is added after 95% ethyl alcohol mixes and is filtered to remove impurity;Paris polyphylla powder is poured into medical ventolin In, it stirs evenly;Konjaku flour is poured into water, quickly stirring keeps konjaku flour completely soluble;
(3) it will be mixed with the mixed liquor of camphor, menthol, 95% ethyl alcohol, the medical ventolin of Paris polyphylla powder is mixed with, is mixed with konjaku flour Aqueous solution, asarum powder and raw gardenia powder are poured into same container, are sufficiently stirred evenly to get analgesic ointment.
4. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: raw in the step (1) Cape jasmine concocting method: weeding out grey bits, picks impurity, then 1-3 hour dry at a temperature of 60 DEG C -80 DEG C, takes out and pulverizes, 80 mesh of mistake Sieve to obtain raw gardenia powder.
5. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: weight in the step (1) Building concocting method: removing impurity, cleans, moisturizes, and shave dries, then 1-3 hours dry at a temperature of 60 DEG C -80 DEG C, takes out It pulverized 80 meshes and obtains Paris polyphylla powder.
6. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: the step (1) is possessed Taro concocting method: removing impurity, cleans, moisturizes, cut sheet, then 1-3 hours dry at a temperature of 60 DEG C -80 DEG C, takes out and pulverizes It crosses 80 meshes and obtains konjaku flour.
7. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: thin in the step (1) Pungent concocting method: removing impurity, sprays clear water, slightly moistens, and dissection is dried in the shade, then 1-3 hours dry at a temperature of 40 DEG C -60 DEG C, takes 80 meshes were pulverized out obtains asarum powder.
8. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: camphor tree in the step (1) Brain concocting method: by camphor booth on clean paper, impurity is removed, absorbs residual grease and moisture, pulverization.
9. a kind of preparation method for relieving pain ointment according to claim 3, it is characterised in that: institute in the step (2) The medical ventolin stated is needed during being added to Paris polyphylla powder in semi-fluid shape.
10. a kind of analgesic ointment claimed in claims 1-2 is in the application of the drug of preparation treatment diabetes.
CN201910463424.4A 2019-05-30 2019-05-30 A kind of analgesic ointment and preparation method thereof Pending CN110151893A (en)

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CN111617182A (en) * 2020-07-16 2020-09-04 张继阳 Muscle-relaxing and collateral-activating vitality activating cream and preparation method thereof
CN113491744A (en) * 2021-08-26 2021-10-12 付宝麟 Traditional Chinese medicine external ointment paste and preparation method and application thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110680870A (en) * 2019-10-14 2020-01-14 李向阳 Pain-relieving itching-relieving swelling-diminishing detoxifying liquid and preparation method thereof
CN111617182A (en) * 2020-07-16 2020-09-04 张继阳 Muscle-relaxing and collateral-activating vitality activating cream and preparation method thereof
CN113491744A (en) * 2021-08-26 2021-10-12 付宝麟 Traditional Chinese medicine external ointment paste and preparation method and application thereof

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Application publication date: 20190823