CN101732447B - External Chinese medicinal composition for treating psoriasis and preparation method thereof - Google Patents
External Chinese medicinal composition for treating psoriasis and preparation method thereof Download PDFInfo
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- CN101732447B CN101732447B CN2010100301513A CN201010030151A CN101732447B CN 101732447 B CN101732447 B CN 101732447B CN 2010100301513 A CN2010100301513 A CN 2010100301513A CN 201010030151 A CN201010030151 A CN 201010030151A CN 101732447 B CN101732447 B CN 101732447B
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Abstract
The invention relates to an external Chinese medicinal composition for treating psoriasis, which consists of the following raw materials in part by weight: 25 to 30 parts of bitter almond kernel, 25 to 30 parts of chaulmoogratree, 8 to 10 parts of croton seed, 0.3 to 0.5 part of blister beetle, and 0.3 to 0.5 part of hydrargyri oxydum rubrum. The raw materials are ground into fine powder together by weight and uniformly mixed with sesame oil for external use. The composition has the advantages of simple treatment method, convenient medication, obvious medicinal effect, no side effects, short treatment course, and complete eradication; and clinical observation of 2,000 psoriasis patients proves that the composition has a cure rate of 92 percent, and prevents relapse.
Description
Technical field
The invention belongs to the field of Chinese medicines, psoriasic external medicine composition of particularly a kind of treatment and preparation method thereof.
Background technology
Psoriasis is a kind of common chronic dermatosis, and traditional Chinese medical science Gu is referred to as “ Bai Mange ", ancient doctor's nationality also is referred to as " psoriasis ".Doctor trained in Western medicine is called psoriasis (Psoriasis), is commonly called as psoriasis, it is characterized in that the pimple that occurs differing in size, and erythema, surface coverage silvery white squama, clear border, and good sending out stretched side and back in scalp, extremity, and the male is more than the women.Recur easily or increase the weight of winter in spring, and alleviate summer and autumn more.
According to investigations, psoriatic sickness rate accounts for 0.1%～3% of world population.By 1998, ten thousand people surplus China psoriatic has reached 280.The investigation of USA in recent years shows that its sickness rate is 2.6%, and the patient reaches 600-700 ten thousand people, is higher than China far away.Psoriasis has become more and more general now, because of the obstinate refractory of this disease, so still be listed in the important subject in department of dermatologry field, the world today, is one of whole world department of dermatologry keypoint control disease.Though psoriasis does not directly influence life, but outbreak repeatedly all the year round, the course of disease is delayed with the passing of time hematozemia wound essence, failure of skin and muscle to be nourished, and uninteresting pruritus, the insomnia of overtaxing one's nerves has had a strong impact on the specious and physically and mentally healthy of patient, and the patient is suffered untold misery.
Psoriasis pathogenic factor more complicated, the cause of disease are not clear and definite as yet.Tcm theory is thought: psoriasis is that promoting blood circulation and detoxication is the key of this disease of treatment because noxious dampness or pyretic toxicity cause a kind of dermatosis of taking place.The western medical treatment psoriasis mainly is to eliminate symptom, avoids further deterioration, can't effect a radical cure and side effect bigger, cost an arm and a leg.The treatment by Chinese herbs of routine at present exists curative effect undesirable, easily recurrence after the drug withdrawal, and therapeutic domain is narrow, and the course of treatment is long, needs partly just have by 1 year positive effect, the expensive deficiency that waits of medical expense.
Summary of the invention
For overcoming the prior art deficiency, the object of the invention is to provide that a kind of drug effect is remarkable, medication makes things convenient for, has no side effect, the psoriasic external medicine composition of treatment of short treating period and non-relapse after healing.
Another object of the present invention has provided the preparation method of this external medicine composition.
The psoriasic external medicine composition of a kind of treatment, it is made up of following raw materials in part by weight: 25～30 parts of Semen Armeniacae Amarums, 25～30 parts of Semen Hydnocarpis, 8～10 parts of Fructus Crotonis, 0.3～0.5 part of Mylabris, 0.3～0.5 part in Hydrargyri Oxydum Rubrum.
Further, described each raw materials in part by weight is preferably:
30 parts of Semen Armeniacae Amarums, 25 parts of Semen Hydnocarpis, 10 parts of Fructus Crotonis, 0.5 part of Mylabris, 0.5 part in Hydrargyri Oxydum Rubrum.
Chinese medicine composition of the present invention can be made into said external preparation for skin dosage form on the pharmaceutics, as unguentum, dip-coating agent etc.
The present invention prepares in accordance with the following methods: be ground into the end after getting above-mentioned each raw material by weight proportion, mix well promptly with Oleum sesami.The amount of Oleum sesami is not trickled and can be attached to skin surface and be advisable drug powder can be applied in the affected part.Described Oleum sesami claims Oleum sesami, Oleum Sesami again, is flavoring agent commonly used in a kind of daily life.
Using method: external, be coated on the affected part, form one deck medicine film, cover the affected part fully with medicine and be advisable, thickness is about 0.1～2.5mm, is coated with once in per two days.
Points for attention: avoid oral.
Pharmacology of the present invention is as follows:
Semen Armeniacae Amarum: hardship, slightly warm in nature, slightly poisonous, return lung, large intestine channel; The sending down the abnormal ascending QI relieving cough and asthma, loosening bowel to relieve constipation is suitable for the trouble of excess syndromes such as ailment said due to cold or exposure, dryness of the intestine.Semen Hydnocarpi: suffering, heat, poisonous; Heat clearing and damp drying is arranged, the effect of detoxicating and killing parasites." detailed outline " record: " main air tinea mange, all skin ulcers of Fructus Myricae rubrae, detoxicating and killing parasites ".Fructus Crotonis: hot, hot, very toxic, return stomach, large intestine channel; But wind-expelling pain-stopping, the eliminating carbuncle cellulitis, the detumescence of relieving oedema or abdominal distension through diuresis or purgation, scabies, pruritus are controlled in external.Mylabris: hot, hot, very toxic, return liver, stomach, kidney channel; Removing blood stasis Xiao wei, merit poison phagedenoma is drawn red foaming, Yong Yu WEIJIA lump, stubborn dermatitis for many years, scrofula, wart, carbuncle are not burst, the dead flesh of malignant boil.It is the hot poisonous product that loose, the energy treating the poisonous disease with poisonous drugs, and dispersing swelling and dissipating binds can be assisted Fructus Crotonis counteracting toxic substances phagedenoma, the removing blood stasis eliminating stagnation.Hydrargyri Oxydum Rubrum: hot, hot, very toxic; There is removing dampness to hold back skin ulcer, the evacuation of pus of drawing out pus by applying a plaster to the affected part, the effect of removing the necrotic tissue and promoting granulation.The present invention is according to the theory of Chinese medicine with poison gram poison, and suitably dosage is suited the remedy to the case; Above-mentioned each material combination is reasonable, complements each other, and has strengthened the medicine itching-relieving and ringworm-eliminating, the evacuation of pus of drawing out pus by applying a plaster to the affected part, and detoxicating and resolving stagnation of pathogens, the effect of removing the necrotic tissue and promoting granulation, thus can effectively treat psoriasis, reach the purpose of thorough elimination.
The present composition, is suited the remedy to the case with poison gram toxicity opinion according to Chinese medicine, and treatment means is simple, medication is convenient, drug effect is remarkable, have no side effect, clinical symptoms rapidly disappears, and short treating period and elimination are thorough, non-relapse after healing.
The specific embodiment
Below in conjunction with embodiment technical scheme of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited thereto.
Embodiment 1:
Semen Armeniacae Amarum 25g, Semen Hydnocarpi 25g, Fructus Crotonis 8g, Mylabris 0.3g, Hydrargyri Oxydum Rubrum 0.3g.
During preparation above-mentioned each raw material is ground into the end, mixes well with Oleum sesami, coating gets final product.
Annotate: pulverize thoroughly for making Mylabris, skin generation discomfort when avoiding the patient to use, use the back of also Mylabris can being shelled during preparation, down together.
Embodiment 2:
Semen Armeniacae Amarum 30g, Semen Hydnocarpi 30g, Fructus Crotonis 10g, the Mylabris 0.5g that shells, Hydrargyri Oxydum Rubrum 0.5g.
During preparation above-mentioned each raw material is ground into the end, mixes well external with Oleum sesami.
Embodiment 3:
Semen Armeniacae Amarum 30g, Semen Hydnocarpi 25g, Fructus Crotonis 10g, the Mylabris 0.5g that shells, Hydrargyri Oxydum Rubrum 0.5g.
During preparation above-mentioned each raw material is ground into the end, mixes well with Oleum sesami, coating gets final product.
Embodiment 4:
Semen Armeniacae Amarum 30g, Semen Hydnocarpi 25g, Fructus Crotonis 10g, Mylabris 0.5g, Hydrargyri Oxydum Rubrum 0.5g.
During preparation above-mentioned each raw material is ground into the end, mixes well with Oleum sesami, coating gets final product.
Embodiment 5:
Semen Armeniacae Amarum 28g, Semen Hydnocarpi 26g, Fructus Crotonis 9g, the Mylabris 0.4g that shells, Hydrargyri Oxydum Rubrum 0.4g.
During preparation above-mentioned each raw material is ground into the end, mixes well external with Oleum sesami.
Embodiment 6:
Semen Armeniacae Amarum 29g, Semen Hydnocarpi 27g, Fructus Crotonis 8g, Mylabris 0.4g, Hydrargyri Oxydum Rubrum 0.3g.
During preparation above-mentioned each raw material is ground into the end, mixes well with Oleum sesami, coating gets final product.
Embodiment 7:
Semen Armeniacae Amarum 27g, Semen Hydnocarpi 25g, Fructus Crotonis 8g, Mylabris 0.4g, Hydrargyri Oxydum Rubrum 0.5g.
During preparation above-mentioned each raw material is ground into the end, mixes well with Oleum sesami, coating gets final product.
For showing the therapeutic effect of Chinese medicine composition of the present invention, through 2000 routine psoriatic's clinical observations, use medicine of the present invention, clinical cure (the chapping of skin ringworm, desquamation decortication, pruritus disappear, and it is normal that skin color recovers) 1840 examples; Produce effects (the chapping of skin ringworm, desquamation decortication disappear, still have skin pruritus) 94 examples; Effective (decortication of the disappearance of chapping of skin ringworm, desquamation alleviates, still has pruritus) 26 examples; Invalid 40 examples; Cure rate is 92%, and does not recur.
Below further set forth the beneficial effect of external medicine composition of the present invention by model case.
Case 1:
Liu, the man, 48 years old, ancon had the red pimple that differs in size, and Rhizoma Euonymus is arranged at the top, enlarge then to be fused into lamellar, scurf Bai Erhou, and with pruritus.Be diagnosed as psoriasis.2008 with the embodiment of the invention 2 Drug therapys, put on the skin in per two days to be coated with once, and second day sx after the medication, the pruritus transference cure, medication was cured after 6 days, and skin surface is smooth, and color is with identical on every side, recurrence so far.
Case 2:
Lee, the man, 26 years old, forearm had the one 10 centimeters red mound of ellipse speckles, scrapes the desquamation of itching, and red damaged, it is invalid to cure for a long time.Used the embodiment of the invention 1 Drug therapy in 2007, put on the skin in per two days and to be coated with once, second day symptom obviously alleviates after the medication, and medication was cured after 8 days, and skin surface is smooth, and color is with identical on every side.
Case 3:
The field, the woman, 27 years old, suffer from the tinea manuum, 2006 with the embodiment of the invention 5 Drug therapys, put on the skin in per two days to be coated with once, and symptom obviously alleviates the same day after the medication, and the transference cure of very itching is put on the skin and is coated with 2 times and promptly cures.
Case 4:
High certain, the woman, 20 years old, suffer from psoriasis more than 5 years, the erythema of Semen Glycines size appears in patient's shank, dry tack free has Rhizoma Euonymus, and blush is arranged on every side, and increases expansion gradually, epidermis thickens, and easily strikes off, and very itches.In March, 2004 is with the embodiment of the invention 3 Drug therapys, puts on the skin in per two days to be coated with once, and symptom obviously alleviates after the medication, the transference cure of very itching, and medication was cured after 16 days, recurred so far.
Case 5:
Poplar, the woman, 46 years old, suffer from surplus the psoriasis universalis 10 year, it is invalid to seek medical advice in many ways, and in March, 2005 is with the embodiment of the invention 3 Drug therapys, put on the skin in per two days to be coated with once, second day sx after the medication, medication was cured after 20 days, recurred so far.
Case 6:
The Wang, the man, 68 years old, two lower limb and foot suffered from surplus the psoriasis 20 year, and it is invalid to seek medical advice in many ways, and in JIUYUE, 2002 is with the embodiment of the invention 4 Drug therapys, puts on the skin in per two days to be coated with once, and medication was cured after one month, recurred so far.
Claims (2)
1. the psoriasic external medicine composition of treatment is characterized in that it is made up of following raw materials in part by weight: 25～30 parts of Semen Armeniacae Amarums, 25～30 parts of Semen Hydnocarpis, 8～10 parts of Fructus Crotonis, 0.3～0.5 part of Mylabris, 0.3～0.5 part in Hydrargyri Oxydum Rubrum.
2. treat psoriasic external medicine composition according to claim 1, it is characterized in that, described raw materials in part by weight is: 30 parts of Semen Armeniacae Amarums, 25 parts of Semen Hydnocarpis, 10 parts of Fructus Crotonis, 0.5 part of Mylabris, 0.5 part in Hydrargyri Oxydum Rubrum.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010100301513A CN101732447B (en) | 2010-01-12 | 2010-01-12 | External Chinese medicinal composition for treating psoriasis and preparation method thereof |
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| CN2010100301513A CN101732447B (en) | 2010-01-12 | 2010-01-12 | External Chinese medicinal composition for treating psoriasis and preparation method thereof |
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| CN101732447B true CN101732447B (en) | 2011-11-02 |
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| CN103349701A (en) * | 2013-06-24 | 2013-10-16 | 李广 | Traditional Chinese medicine composition for treating psoriasis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1151885A (en) * | 1996-09-12 | 1997-06-18 | 李青坡 | External-use Chinese medicine prepn for psoriasis |
| CN1452992A (en) * | 2002-04-25 | 2003-11-05 | 刘中良 | Externally applied psoriasis-treating medicine and its prepn |
| CN1965940A (en) * | 2006-11-23 | 2007-05-23 | 李剑 | Chinese medicinal composition for treating psoriasis |
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2010
- 2010-01-12 CN CN2010100301513A patent/CN101732447B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1151885A (en) * | 1996-09-12 | 1997-06-18 | 李青坡 | External-use Chinese medicine prepn for psoriasis |
| CN1452992A (en) * | 2002-04-25 | 2003-11-05 | 刘中良 | Externally applied psoriasis-treating medicine and its prepn |
| CN1965940A (en) * | 2006-11-23 | 2007-05-23 | 李剑 | Chinese medicinal composition for treating psoriasis |
Non-Patent Citations (6)
| Title |
|---|
| 宋兆友.常用皮肤病中药外用制剂介绍.《皮肤病与性病》.2006,第28卷(第1期),23-25. * |
| 尚佩生等.中医皮肤病外用法理论基础与组方用药规律探讨.《辽宁中医药大学学报》.2009,第11卷(第2期),17-18. * |
| 林熙然.隋代到清代中医医籍中有关银屑病的资料综述.《中国中西医结合皮肤性病学杂志》.2002,第1卷(第1期),60-63. * |
| 欧阳恒.论难治性皮肤病之诊治.《湖南中医药大学学报》.2007,第27卷(第4期),4-6. * |
| 白彦萍.中医外治法及其在皮肤科的应用.《中国中西医结合皮肤性病学杂志》.2003,第2卷(第1期),69-71. * |
| 聂兆伟等.历代医家论治银屑病.《中医研究》.2009,第22卷(第10期),59-62. * |
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Granted publication date: 20111102 Termination date: 20140112 |