CN101703651B

CN101703651B - Medicament for treating diabetic gangrene

Info

Publication number: CN101703651B
Application number: CN200910172678.7A
Authority: CN
Inventors: 张国忠
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-11-24
Filing date: 2009-11-24
Publication date: 2015-01-21
Anticipated expiration: 2029-11-24
Also published as: CN101703651A

Abstract

The invention discloses a medicament for treating diabetic gangrene, and relates to a Chinese medicinal medicament. The medicament is characterized by preparing from the following raw materials in part by weight: 7 to 13 parts of rhubarb, 7 to 13 parts of sanguisuga, 5 to 12 parts of dragon's blood, 5 to 12 parts of chicken's gizzard-membrane, 4 to 8 parts of frankincense, 4 to 8 parts of myrrh, 5 to 12 parts of Chinese angelica, 5 to 12 parts of szechuan lovage rhizome, 5 to 12 parts of radix astragali, 5 to 12 parts of liquoric root and 5 to 12 parts of dahurian angelica root. When the medicament is prepared, the raw material medicaments are respectively ground and mixed to prepare powders; and the raw material medicaments also can be ground and mixed, and then sesame oil is added into the mixture to prepare ointment. The prepared Chinese medicinal medicament has the obvious bacteriostasis, enhances the body immunity against pathogenic bacteria, has the effects of eliminating pathogen to support vital qi, diminishing inflammation and expelling toxin, relieving swelling to stop pain, removing necrosis and promoting granulation and the like, promotes fibroblast to grow and wound surfaces to heal quickly, and can treat thanatosis caused by diabetes mellitus effectively.

Description

A kind of medicine for the treatment of diabetic gangrene

Technical field:

The present invention relates to Chinese medicine, is the medicine being used for the treatment of diabetic gangrene further.

Background technology:

Diabetes still belong to lifelong chronic disease at present, if control undesirable, there will be multiple complications, and wherein diabetic gangrene is exactly comparatively serious one.If diabetes blood glucose is too high, carbohydrate metabolism can not meet the physiological need of human body, and human body will employ the fat of storage to supply energy.The product of significant quantities of fat metabolism can be deposited on blood vessel wall, diabetes patient is owing to lacking insulin, Proteometabolism can be accelerated, auxin increases, and immune complex increases, and these can cause microvascular endothelial injury, cause microcirculation disturbance, simultaneously in the environment of hyperglycemia, hemoglobin generation glycosylation oxygen exchange capacity lowers, and causes histanoxia.Cause luminal stenosis or the obstruction of lower limb trunk; Hyperglycemia, microcirculation disturbance also can cause peripheral nerve dysfunction, cause necrosis when acro-ischemia is serious; Meanwhile, blood glucose height provides good nutrition for antibacterial, easily causes infection, occurs festering in local.Necrosis adds infection, just result in diabetic gangrene's (diabetic foot).Diabetic gangrene's disability rate is high, and modern medicine still lacks fruitful method to this.

Summary of the invention:

The object of this invention is to provide a kind of manufacture simple, easy to use, curative effect is better, is used for the treatment of the Chinese medicine of diabetic gangrene.

The object of the invention is to be realized by following scheme: a kind of medicine for the treatment of diabetic gangrene, it is characterized in that being made up of the raw material of following weight parts: Radix Et Rhizoma Rhei 7 ~ 13 parts, Hirudo 7 ~ 13 parts, Sanguis Draxonis 5 ~ 12 parts, Endothelium Corneum Gigeriae Galli 5 ~ 12 parts, Olibanum 4 ~ 8 parts, Myrrha 4 ~ 8 parts.

Preferred version is: Radix Et Rhizoma Rhei 8 ~ 12 parts, Hirudo 8 ~ 12 parts, Sanguis Draxonis 7 ~ 10 parts, Endothelium Corneum Gigeriae Galli 7 ~ 10 parts, Olibanum 5 ~ 7 parts, Myrrha 5 ~ 7 parts.

Preferred plan: Radix Et Rhizoma Rhei 10 parts, Hirudo 10 parts, Sanguis Draxonis 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Olibanum 6 parts, Myrrha 6 parts.

Manufacture method: during making, can by above-mentioned raw materials medicine, and after pulverizing separately, mixing, makes powder; Also can pulverize rear mixing separately, make ointment with Oleum sesami, during with Oleum sesami, many by reducing, be adjusted to rare thick moderate.

In the present invention, also can add Radix Angelicae Sinensis 5 ~ 12 parts, Rhizoma Chuanxiong 5 ~ 12 parts, the Radix Astragali (system) 5 ~ 12 parts, 5 ~ 12 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 5 ~ 12 parts.

Preferred version is: Radix Angelicae Sinensis 6 ~ 10 parts, Rhizoma Chuanxiong 6 ~ 10 parts, the Radix Astragali (system) 6 ~ 10 parts, 6 ~ 10 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 6 ~ 10 parts.

Preferred plan is: Radix Angelicae Sinensis 8 parts, Rhizoma Chuanxiong 8 parts, the Radix Astragali (system) 8 parts, 8 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 8 parts.

In the present invention: Radix Et Rhizoma Rhei, purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, pushes away Chen Zhixin.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire.Hirudo, stimulates the menstrual flow, removing blood stasis with potent drugs, detumescence.Control lump in the abdomen stomachache, the disease such as blood-retention, traumatic blood stasis are had a pain, carbuncle erysipelas.Sanguis Draxonis, promoting blood circulation to remove blood stasis, analgesic therapy, hemostasia and promoting granulation, sore.Control treating swelling and pain by traumatic injury, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Endothelium Corneum Gigeriae Galli, can stagnant, the strengthening the spleen and stomach of removing food stagnancy, putrefaction-removing granulation-promoting.The symptom such as treatment food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition.Olibanum, regulating QI, invigorates blood circulation, and pain relieving chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore.Myrrha, loose blood blood stasis removing, subduing swelling and relieving pain.Control traumatic injury, incised wound, all pains of trusted subordinate, lump in the abdomen, ulcer sore pain.Radix Angelicae Sinensis, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, ulcer sores.Rhizoma Chuanxiong, activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, ulcer sores, rheumatic arthralgia.The Radix Astragali, QI invigorating is just protected, because of table, poison holding, evacuation of pus, granulation promoting, hemopoietic, sore.Radix Glycyrrhizae, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.The Radix Angelicae Dahuricae, expelling wind and cold, understand things pain-stopping, detumescence and apocenosis.

Take the Chinese medicine that the present invention makes, there is obvious bacteriostasis, strengthen human body to pathogenic bacteria resistance, and play the effects such as its eliminating pathogenic factor for supporting vital QI, antiinflammatory toxin expelling, detumescence town pain, removing the necrotic tissue and promoting granulation, promote to impel wound surface quickly-healing by fibroblastic growth.Effectively can treat the gangrene that diabetes cause.

Testing data:

1, function cures mainly

Invigorate blood circulation, blood stasis dispelling, putrefaction removing, granulation promoting, sore, is used for the treatment of diabetic gangrene.

2, Therapeutic Method

During use, after aseptic process is carried out in trouble face, being spread on trouble face, or making ointment with Oleum sesami, be applied to trouble face by dry for powder face of the present invention, once-a-day, 7 days is a course for the treatment of.

3, efficacy assessment standard

Effective: symptom disappears substantially, observe 3 months without recidivist; Take a turn for the better: symptom alleviates.Invalid: not reach improvement target person.

4, therapeutic effect

The present invention treats case 156 example.Wherein, less than 40 years old 6 example, 41 ~ 50 years old 27 example, 51 ~ 60 years old 59 example, more than 60 years old 64 example, man 97 example, female 59 example, max age 83 years old, minimum 22 years old; The course of disease is the longest 1.2 years, the shortest 1 week, the course for the treatment of in the longest October, the shortest 5 days, and through treatment, effective 132 examples, account for 84.6%, and take a turn for the better 22 examples, accounts for 14.1%, total effective rate 98.7%, and invalid 2 examples, account for 1.3%.

Concrete case:

1, king so-and-so, female, 47 years old, Hua County, Henan Province Lao Dianzhen people, in March, 2008 went to a doctor, and suffers from diabetes 7 years, uses oral antidiabetic drug always, and Morbidity control is unsatisfied with.In March before medical, biped toes, toenail blackening, analgesis, sensation is sent out cool.With medicine of the present invention January, lower limb alternating temperature, creeping chill disappears, and the pain sensation is recovered, and biped toe, toenail color of the leather shoal.Take February again, all diseases are accused more, not more repeatedly.

2, Zhang, man, 65 years old.Hua County, Henan Province little Pu village people, was gone to a doctor in April, 2009.Patient have diabetic history.Time medical, patient's left foot back of the body is red and swollen, and three-toed festers necrosis, and root ulcer develops to instep.With medicine of the present invention January, ulcer is obviously driven, then takes February, and rotten position skin healing is intact, color and luster be normally as good as.

3, Chen, man, 70 years old, area just outside a city gate people from town, Hua County, Henan Province, in May, 2008 went to a doctor.Patient suffers from diabetes in 2005, controls blood glucose with insulin always, and start to occur that biped skin-color is dark, send out cool in March, 2008, biped little toe is purple dark, but non-ulceration, two pulsation of foot dorsal artery weakens.With medicine of the present invention February, color and luster be normally as good as, biped alternating temperature.

4, Chu so-and-so, man, 73 years old, little Pu township, Hua County, Henan Province Yang Gong people from shop, diabetes caused right crus of diaphragm toe downright bad, and through provincial hospital diagnosis, doctor advised cuts toe.In April, 2008 this place medical after, on the basis of the downright bad skin of debridement, the Chinese medicine utilizing the present invention to make is smeared, and inflammation disappeared on 30th.

Detailed description of the invention:

Below in conjunction with embodiment, the invention will be further described.

Embodiment 1: choose Radix Et Rhizoma Rhei 7.5 grams, Hirudo 7.5 grams, Sanguis Draxonis 5.5 grams, Endothelium Corneum Gigeriae Galli 5.5 grams, Olibanum 4.5 grams, Myrrha 4.5 grams.During making, can by above-mentioned raw materials medicine, after pulverizing separately, mixing, makes powder; Also can pulverize rear mixing separately, make ointment with Oleum sesami, during with Oleum sesami, many by reducing, be adjusted to rare thick moderate.

Embodiment 2: choose Radix Et Rhizoma Rhei 12.5 grams, Hirudo 12.5 grams, Sanguis Draxonis 11.5 grams, Endothelium Corneum Gigeriae Galli 11.5 grams, Olibanum 7.5 grams, Myrrha 7.5 grams.Manufacture method is with embodiment 1.

Embodiment 3: choose Radix Et Rhizoma Rhei 8.5 grams, Hirudo 8.5 grams, Sanguis Draxonis 7.5 grams, Endothelium Corneum Gigeriae Galli 7.5 grams, Olibanum 5.5 grams, Myrrha 5.5 grams.Manufacture method is with embodiment 1.

Embodiment 4: choose Radix Et Rhizoma Rhei 11.5 grams, Hirudo 11.5 grams, Sanguis Draxonis 9.5 grams, Endothelium Corneum Gigeriae Galli 9.5 grams, Olibanum 6.5 grams, Myrrha 6.5 grams.Manufacture method is with embodiment 1.

Embodiment 5: choose Radix Et Rhizoma Rhei 7.5 grams, Hirudo 7.5 grams, Sanguis Draxonis 5.5 grams, Endothelium Corneum Gigeriae Galli 5.5 grams, Olibanum 4.5 grams, Myrrha 4.5 grams, Radix Angelicae Sinensis 5.5 parts, Rhizoma Chuanxiong 5.5 parts, the Radix Astragali (parch) 5.5 parts, 5.5 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 5.5 parts.During making, can by above-mentioned raw materials medicine, after pulverizing separately, mixing, makes powder; Also can pulverize rear mixing separately, make ointment with Oleum sesami.

Embodiment 6: choose Radix Et Rhizoma Rhei 12.5 grams, Hirudo 12.5 grams, Sanguis Draxonis 11.5 grams, Endothelium Corneum Gigeriae Galli 11.5 grams, Olibanum 7.5 grams, Myrrha 7.5 grams, Radix Angelicae Sinensis 11.5 parts, Rhizoma Chuanxiong 5.5 parts, the Radix Astragali (parch) 11.5 parts, 11.5 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 11.5 parts.Manufacture method is with embodiment 5.

In various embodiments of the present invention, Plumbum preparatium also claims Plumbum preparatium, and Oleum Sesami refers to Oleum sesami.Radix Dipsaci can be substituted by the Cortex Eucommiae.

Other corresponding compositions also can be increased in prescription of the present invention.

Claims

1. an external curing diabetic gangrene's medicine, it is characterized in that being made up of the raw material of following weight parts: Radix Et Rhizoma Rhei 7 ~ 13 parts, Hirudo 7 ~ 13 parts, Sanguis Draxonis 5 ~ 12 parts, Endothelium Corneum Gigeriae Galli 5 ~ 12 parts, Olibanum 4 ~ 8 parts, Myrrha 4 ~ 8 parts.

2. the medicine of a kind of external curing diabetic gangrene according to claim 1, is characterized in that each component is: Radix Et Rhizoma Rhei 10 parts, Hirudo 10 parts, Sanguis Draxonis 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Olibanum 6 parts, Myrrha 6 parts.