CN106692370A - Traditional Chinese medicine decoction for treating lower limb ulcer and preparation method thereof - Google Patents

Traditional Chinese medicine decoction for treating lower limb ulcer and preparation method thereof Download PDF

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CN106692370A
CN106692370A CN201710192835.5A CN201710192835A CN106692370A CN 106692370 A CN106692370 A CN 106692370A CN 201710192835 A CN201710192835 A CN 201710192835A CN 106692370 A CN106692370 A CN 106692370A
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traditional chinese
lower limb
ulcer
root
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江秀利
任凤兰
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Abstract

The invention belongs to the technical field of traditional Chinese medicine and medication, and particularly relates to a traditional Chinese medicine decoction for treating lower limb ulcer and a preparation method thereof. The traditional Chinese medicine decoction for treating the lower limb ulcer is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10 to 20 parts of radix angelicae sinensis, 10 to 20 parts of radix salviae miltiorrhizae, 15 to 25 parts of radix angelicae, 8 to 16 parts of frankincense, 8 to 16 parts of myrrh, 10 to 20 parts of pangolin, 6 to 12 parts of rhizoma ligustici wallichii, 6 to 12 parts of bitter almond, 3 to 9 parts of chrysanthemum flowers and 8 to 16 parts of liquorice roots. The traditional Chinese medicine decoction has the advantages that traditional Chinese medicinal materials with different medicine effects are used, are scientifically matched and supplement each other to achieve the synergistic effect; the effects of removing slough, promoting growth of tissue regeneration, promoting blood circulation to remove blood stasis, dredging the channel, promoting circulation of blood and invigorating pulse-beat are achieved; the traditional Chinese medicine decoction is used for blood stasis, varicosity, dark skin color, ulcer erosion and the like.

Description

Treat traditional Chinese herbal decoction of the ulcer of lower limb and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese medicine technology, and in particular to a kind of traditional Chinese herbal decoction for treating the ulcer of lower limb and its preparation Method.
Background technology
So-called problem wound refers to be unable to cured person via traditional general medicine or methods of surgical treatment, and this may It is to carry out normal repair for the situation of patient's whole system or part is impermissible for wound.These include it is stasis it Wound healing is bad after vascular lesion, the wound not healed, amputation and diabetes person (diabetic ulcer is the one of diabetes Plant complication) etc..No matter what reason is caused, the subject matter of poor wound healing goes out in local infection and tissue blood filling The relation of the bad reciprocal causation of note.
It is more than 70% by ulcer proportion caused by varication in all of ulcer of lower limb, 20% is other Veins disease, remaining is artery disease, Buerger's disease, lymphatic block and nerve disease less than 10% Disease, metabolic disorder, hematological system disorder and panniculitis etc. are caused.It can be seen that, the ulcer of lower limb is mainly by peripheral vascular disease institute Cause, varicose ulcer is also called congestive ulcer, the main cause veins of lower extremity blood stasis of blood is accumulated and caused.
Venous leg ulcers, are commonly called as " always rotten lower limb ", are the common clinical manifestations of lower limb disease.Venous leg is burst Ulcer usually recurrent exerbation, ulcer obstinate, have a strong impact on the normal life of patient, therefore venous leg ulcers once occur Phenomenon, patient should arrive in time regular hospital vascular surgery see a doctor, to investigate thoroughly the cause of disease, suit the remedy to the case.
Artery sclerosis is a kind of non-inflammation lesion of artery, and ductus arteriosus wall can be made to thicken, be hardened, and is followed the string, tube chamber It is narrow.The vascular diseases that artery sclerosis is with age and occurs, its rule is typically to be occurred in adolescence, into Senectitude is aggravated, morbidity.
The ulcer of lower limb for healing is difficult to for more than, is taken medicine, have an injection, infused, great pain is brought to patient, had an injection, defeated The side effect that liquid band is come is big.Clinical treatment weak curative effect, slowly effect, wound long-time disunion, great pain is brought to patient, A kind of effective medicine is needed badly to improve such case.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of traditional Chinese herbal decoction for treating the ulcer of lower limb, can Blood viscosity is reduced, tail vein is expanded, accelerates VPV, be effectively improved lower limb blood circulation, putrefaction-removing granulation-promoting, promoting blood circulationization The stasis of blood, dredging the channel, promoting circulation of blood is promoted blood circulation；Present invention simultaneously provides its preparation method.
The traditional Chinese herbal decoction of the treatment ulcer of lower limb of the present invention, is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 10-20 parts, red sage root 10-20 parts, root of Dahurain angelica 15-25 parts, frankincense 8-16 parts, myrrh 8-16 parts, pangolin 10-20 parts, Ligusticum wallichii 6-12 Part, semen armeniacae amarae 6-12 parts, chrysanthemum 3-9 parts and Radix Glycyrrhizae 8-16 parts.
Preferably, the traditional Chinese herbal decoction of the described treatment ulcer of lower limb, is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 12-18 parts, red sage root 12-18 parts, root of Dahurain angelica 18-22 parts, frankincense 11-13 parts, myrrh 10-14 parts, pangolin 13-17 parts, Ligusticum wallichii 8- 10 parts, semen armeniacae amarae 8-10 parts, chrysanthemum 5-7 parts and Radix Glycyrrhizae 10-14 parts.
It is highly preferred that the traditional Chinese herbal decoction of the described treatment ulcer of lower limb, is made up of the Chinese medicine material of following parts by weight：When Return 15 parts, 15 parts of the red sage root, 19 parts of the root of Dahurain angelica, 12 parts of frankincense, 12 parts of myrrh, 15 parts of pangolin, 9 parts of Ligusticum wallichii, 9 parts of semen armeniacae amarae, chrysanthemum 6 12 parts of part and Radix Glycyrrhizae.
The preparation method of the traditional Chinese herbal decoction of the described treatment ulcer of lower limb, step is as follows：
(1) Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae are added into 20-40 points of water immersion Clock, slow fire is boiled 15-25 minutes, add pangolin continue to boil 5-15 minutes, when water halves, pour out and boil liquid, medicine after It is continuous to stay in pot；
(2) to adding water, slow fire to boil in pot 5-15 minutes, pour out to boil liquid and step (1) gained and boil liquid and mix, obtain The traditional Chinese herbal decoction of the described treatment ulcer of lower limb.
Described preparation method is preferably：
(1) water is added to soak 30 minutes Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae, Slow fire is boiled 20 minutes, adds pangolin to continue to boil 10 minutes, when water halves, and is poured out and is boiled liquid, and medicine continues to stay in pot In；
(2) to adding water, slow fire to boil in pot 10 minutes, pour out to boil liquid and step (1) gained and boil liquid and mix, obtain institute The traditional Chinese herbal decoction of the treatment ulcer of lower limb stated.
Wherein：
In step (1), the amount of described addition water is Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum 4.0-5.5 times, preferably 4.8 times of flower, Radix Glycyrrhizae and pangolin gross mass.
In step (2), the amount of described addition water is Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum 3.0-3.5 times, preferably 3.2 times of flower, Radix Glycyrrhizae and pangolin gross mass.
Drug action mechanism in the present invention is as follows：
Radix Angelicae Sinensis：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot It is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.Motherland's medical science is recognized For, Radix Angelicae Sinensis is sweet and weigh, therefore can specially enrich blood, its gas is light and pungent, therefore again can promoting circulation of blood, bowl spares has, has benefit in row, be in blood will Medicine.Thus, it can enrich blood, and can invigorate blood circulation, and can both stimulate the menstrual flow, and can be active.Modern research suggests that to blood and cardiovascular system Influence have：Plasma clotting times extend, and can reduce thrombus, and thrombus growth rate slows down, and has obvious anti thrombotic action.
The red sage root：Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, lump in the abdomen lump in the abdomen product It is poly-, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.
The root of Dahurain angelica：Wind-dispelling, eliminating dampness, detumescence, analgesic.Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, Leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.
Frankincense：Blood-activating and qi-promoting is relieved pain, detumescence and promoting granulation.For chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis, disease Lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Myrrh：Scattered stasis pain, detumescence and promoting granulation.For chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea Amenorrhea postpartum stasis , Disorder lump in the abdomen abdomens Bitterly, the treatment of the illnesss such as arthralgia pain due to rheumatism, traumatic injury, carbuncle swells sore.
Pangolin：Promoting blood circulation disappears carbuncle apocenosis, searches that wind is active, and stimulate the menstrual flow lower breast.Cure mainly ulcer, sore swollen toxin, wind-cold-dampness arthralgia, hemostasis Amenorrhoea, a lump in the abdomen causing distension and pain, alactation.
Ligusticum wallichii：Promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Cure mainly air-cooled headache rotation dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, warp Close, have difficult labour, postpartum stasis block bitterly, ulcer sores.For irregular menstruation, closed dysmenorrhea, lump in the abdomen is suffered from abdominal pain, chest side of body shouting pain, tumbling and swelling, Headache, arthralgia pain due to rheumatism.
Semen armeniacae amarae：Sending down abnormally ascending is relieving cough and asthma, relaxes bowel.For cough and asthma, fullness sensation in chest abundant expectoration, deficiency of blood Tianjin is withered, dry constipation of intestines. Chrysanthemum：Wind heat-clearing is dissipated, flat liver improving eyesight is clearing heat and detoxicating.For anemopyretic cold, dizziness of having a headache, red eye, swell pain, eyes is dim-sighted, sore carbuncle Pyogenic infections.
Radix Glycyrrhizae：Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, burnout is weary Power, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
Theoretical according to lung associating with skin and hair, modern study proves that the fat oil contained by semen armeniacae amarae can soften keratoderma, moistens Dry skin care, plays the role of to protect peripheral vessel and histoorgan.Chrysanthemum coordinates with semen armeniacae amarae and can press down bactericidal, fungi, additionally, also The active tyrosine that can suppress internal eliminates pigmentation, freckle, blackspot etc., so as to reach the effect of corruption of dispelling.
Frankincense is compatible with myrrh, there is regulating qi and activating blood, analgesic therapy, the effect for chasing after poison.Control qi and blood stagnation, trusted subordinate's pain, ulcerative carbuncle Pyogenic infections, traumatic injury etc.；Myrrh with promoting blood circulation to remove blood stasis as will, be longer than detumescence.
Pangolin is compatible with Ligusticum wallichii, has functions that promoting blood circulation, promote breath and open depression, searches wind and removing obstruction in channels.Modern medicine is thought to wear Naze can stimulate circulation, and reduce WBV, significantly reduce platelet adhesion reaction effect, there is moderate anticoagulation；Wear in addition Naze can also reduce vascular resistence, and expansion of blood vessels improves tolerance of the tissue to anoxic, keeps organizational vitality；With promotion The effect of blood capillary proliferation, is effectively improved local blood circulation.
More than all medicines cure mainly and effect is referred to：Higher learning of Chinese medicine undergraduate course teaching material《Chinese pharmacology》.
Below for clinical test is summarized：Clinical testing treatment ulcer of lower limb patient 37.
Ulcer of lower limb symptom：
(1) medical histories such as bacterium infection are injured outside having, the time is mostly more long.
(2) local skin ulceration, erosion, can there is purulent secretion.With swelling, pain, skin color is dimmed, blackening.
(3) acute patient can have heating, and systemic toxicity profiles symptom；Chronic patient constitutional symptom is not obvious.
(4) lower limb send out cool, pain, dimmed skin color, purpling, blackening；Lower limb injury, skin breach, do not recover for a long time；Sugar The foot ulcers that urine disease causes；The lower limb extravasated blood that phlebitis, varication cause.
Therapeutic scheme：The traditional Chinese herbal decoction of the oral present invention treatment ulcer of lower limb, daily 500 milliliters, a point morning and evening takes twice. 2 months are taken for 1 course for the treatment of, new disease 1 course for the treatment of of medication, 3 courses for the treatment of of lingering disease medication.
Treatment standard：
Recovery from illness：Pain disappears, and wound healing, skin color is normal.
Effectively：Wound diminishes, lighter.
It is invalid：Non-healing wounds, still into black, pain does not mitigate skin.
Treatment results：Ulcer of lower limb patient accounts for 32.4% by after treatment, fully recovering 12；Effective 21, account for 56.8%； Invalid 4, account for 10.8%, total effective rate 89.2%.
It is exemplified below several model cases：
Case 1：Patient Zhao so-and-so, man, 55 years old, because varication causes lower extremity swelling and distension, pain.The oral present invention is implemented Example 3 treats the traditional Chinese herbal decoction of the ulcer of lower limb, and daily 500 milliliters, a point morning and evening takes twice.Swelling, pain disappear clothes after two months Lose.
Case 2：Patient Lee so-and-so, female, 48 years old, because diabetes cause foot ulcers.The oral embodiment of the present invention 3 is treated The traditional Chinese herbal decoction of the ulcer of lower limb, daily 500 milliliters, a point morning and evening takes twice.Pain disappears after taking four months, wound healing, Skin color recovers normal.
Case 3：Patient Jia XX, man, 75 years old, because artery sclerosis triggers pedal skin colour-darkening, blackening, local skin Skin ulceration, erosion, open-ended, and with purulent secretion.The oral embodiment of the present invention 3 treats the traditional Chinese herbal decoction of the ulcer of lower limb, Daily 500 milliliters, a point morning and evening takes twice.Pain disappears after taking half a year, and wound healing, skin color shoals.
Clinical drug of the present invention is using showing to have the following advantages：
(1) the selected Chinese herbal medicine of the present invention meets《Pharmacopoeia of People's Republic of China》Regulation.
(2) present invention carries out scientific compatibility using the Chinese medicine of different drug effects, complements each other, with synergy, can Putrefaction-removing granulation-promoting, promoting blood circulation and removing blood stasis, dredging the channel, promoting circulation of blood is promoted blood circulation.For hypostasis, varication, the colour of skin to be dark and gloomy, curing ulcer erosion Deng.
(3) traditional Chinese herbal decoction of the present invention treatment ulcer of lower limb can reduce blood viscosity, expand tail vein, accelerate blood Flow velocity degree, is effectively improved lower limb blood circulation.Through long-term observation arteriosclerotic, local blood capillary proliferation can be promoted, Improve blood supply, the ulcer that ischemic necrosis occur can heal.
(4) present invention boils prescription method using tradition, it is easy to receive, patient compliance rate is high.
(5) preparation method of the present invention, it is scientific and reasonable, simple and easy to apply.
Specific embodiment
With reference to embodiment, the present invention will be further described, but does not limit the present invention.
Embodiment 1
The traditional Chinese herbal decoction of the described treatment ulcer of lower limb, is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 10g, pellet Ginseng 10g, root of Dahurain angelica 15g, frankincense 8g, myrrh 8g, pangolin 10g, Ligusticum wallichii 6g, semen armeniacae amarae 6g, chrysanthemum 3g and Radix Glycyrrhizae 8g.
Its preparation method is as follows：
(1) Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae are added into water 450mL immersions 20 Minute, slow fire is boiled 15 minutes, adds pangolin to continue to boil 5 minutes, when water halves, and is poured out and is boiled liquid, and medicine continues to stay In pot；
(2) to water 300mL is added in pot, slow fire boils 5 minutes, pours out and boils liquid and boil liquid obtained by step (1) and mix, Obtain the traditional Chinese herbal decoction of the described treatment ulcer of lower limb.
Embodiment 2
The traditional Chinese herbal decoction of the described treatment ulcer of lower limb, is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 20g, pellet Ginseng 20g, root of Dahurain angelica 25g, frankincense 16g, myrrh 16g, pangolin 20g, Ligusticum wallichii 12g, semen armeniacae amarae 12g, chrysanthemum 9g and Radix Glycyrrhizae 16g.
Its preparation method is as follows：
(1) Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae are added into water 660mL immersions 40 Minute, slow fire is boiled 25 minutes, adds pangolin to continue to boil 15 minutes, when water halves, and is poured out and is boiled liquid, and medicine continues to stay In pot；
(2) to water 440mL is added in pot, slow fire boils 15 minutes, pours out to boil liquid and boil liquid with step (1) gained and mixes Close, obtain the traditional Chinese herbal decoction of the described treatment ulcer of lower limb.
Embodiment 3
The traditional Chinese herbal decoction of the described treatment ulcer of lower limb, is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 15g, pellet Ginseng 15g, root of Dahurain angelica 19g, frankincense 12g, myrrh 12g, pangolin 15g, Ligusticum wallichii 9g, semen armeniacae amarae 9g, chrysanthemum 6g and Radix Glycyrrhizae 12g.
Its preparation method is as follows：
(1) Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae are added into 600mL water immersion 30 Minute, slow fire is boiled 20 minutes, adds pangolin to continue to boil 10 minutes, when water halves, and is poured out and is boiled liquid, and medicine continues to stay In pot；
(2) to adding water, slow fire to boil in pot 10 minutes, pour out to boil liquid and step (1) gained and boil liquid and mix, obtain institute The traditional Chinese herbal decoction of the treatment ulcer of lower limb stated.

Claims (6)

1. a kind of traditional Chinese herbal decoction for treating the ulcer of lower limb, it is characterised in that：It is made up of the Chinese medicine material of following parts by weight：Radix Angelicae Sinensis 10-20 parts, red sage root 10-20 parts, root of Dahurain angelica 15-25 parts, frankincense 8-16 parts, myrrh 8-16 parts, pangolin 10-20 parts, Ligusticum wallichii 6-12 Part, semen armeniacae amarae 6-12 parts, chrysanthemum 3-9 parts and Radix Glycyrrhizae 8-16 parts.
2. it is according to claim 1 treatment the ulcer of lower limb traditional Chinese herbal decoction, it is characterised in that：By in following parts by weight Medicine raw material is made：Radix Angelicae Sinensis 12-18 parts, red sage root 12-18 parts, root of Dahurain angelica 18-22 parts, frankincense 11-13 parts, myrrh 10-14 parts, pangolin 13-17 parts, Ligusticum wallichii 8-10 parts, semen armeniacae amarae 8-10 parts, chrysanthemum 5-7 parts and Radix Glycyrrhizae 10-14 parts.
3. it is according to claim 2 treatment the ulcer of lower limb traditional Chinese herbal decoction, it is characterised in that：By in following parts by weight Medicine raw material is made：15 parts of Radix Angelicae Sinensis, 15 parts of the red sage root, 19 parts of the root of Dahurain angelica, 12 parts of frankincense, 12 parts of myrrh, 15 parts of pangolin, 9 parts of Ligusticum wallichii, hardship 12 parts of 9 parts of almond, 6 parts of chrysanthemum and Radix Glycyrrhizae.
4. the preparation method of the traditional Chinese herbal decoction of any described treatment ulcers of lower limb of a kind of claim 1-3, it is characterised in that：Step It is rapid as follows：
(1) water is added to soak 20-40 minutes Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum and Radix Glycyrrhizae, Slow fire is boiled 15-25 minutes, adds pangolin to continue to boil 5-15 minutes, when water halves, and is poured out and is boiled liquid, and medicine continues to stay In pot；
(2) to adding water, slow fire to boil in pot 5-15 minutes, pour out to boil liquid and step (1) gained and boil liquid and mix, obtain described in The treatment ulcer of lower limb traditional Chinese herbal decoction.
5. it is according to claim 4 treatment the ulcer of lower limb traditional Chinese herbal decoction preparation method, it is characterised in that：Step (1) In, the amount of described addition water is that Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum, Radix Glycyrrhizae and pangolin are total 4.0-5.5 times of quality.
6. it is according to claim 4 treatment the ulcer of lower limb traditional Chinese herbal decoction preparation method, it is characterised in that：Step (2) In, the amount of described addition water is that Radix Angelicae Sinensis, the red sage root, the root of Dahurain angelica, frankincense, myrrh, Ligusticum wallichii, semen armeniacae amarae, chrysanthemum, Radix Glycyrrhizae and pangolin are total 3.0-3.5 times of quality.
CN201710192835.5A 2017-03-28 2017-03-28 Traditional Chinese medicine decoction for treating lower limb ulcer and preparation method thereof Pending CN106692370A (en)

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Publication number Priority date Publication date Assignee Title
CN110064025A (en) * 2019-06-03 2019-07-30 嘉兴市中医医院 A kind of blood activating and promoting tissue regeneration Chinese medicine and preparation method thereof
CN110064025B (en) * 2019-06-03 2021-05-11 嘉兴市中医医院 Traditional Chinese medicine for treating chronic skin ulcer and preparation method thereof

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Application publication date: 20170524