CN106421410A - Traditional Chinese medicine composition for treating diabetic foot - Google Patents
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Abstract
The invention relates to a traditional Chinese medicine composition for treating diabetic foot, which belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared by 10 to 20 parts of cassia twigs, 10 to 20 parts of safflower, 5 to 15 parts of caulis impatientis, 17 to 24 parts of caulis spatholobi, 5 to 15 parts of fructus liquidambaris, 6 to 17 parts of bletilla, 7 to 15 parts of frankincense, 6 to 15 parts of myrrh, and 10 to 20 parts of pepper. The formula is unique and the production process is simple and easy to use, the traditional Chinese medicine composition has a significant effect, and is mainly used for diabetic foot patients with Qi and Yin deficiency, and blood stasis. The ingredients with heat clearing, detoxification, blood invigorating and stasis removal, channel and collateral clearing effects coordinate one another to effectively improve the microcirculation of the wound, to promote the recovery of damaged nerve tissue function, to promote detachment of necrosis tissues, to promote skin epithelial cell growth, and to accelerate the absorption of inflammation, promote granulation and epithelial tissue growth and wound healing, and improve life quality of patients. In addition, the traditional Chinese medicine is highly safe.
Description
Technical field
A kind of Chinese medicine composition for treating diabetic foot of the present invention, belongs to technical field of Chinese medicines.
Background technology
Diabetic foot refers to that diabetic foot makes lower limb defencive function go down due to neuropathy, big blood vessel and micro- blood
Pipe pathological changes make the not enough morbid state for causing microcirculation disturbance and ulcer and gangrene occurring of arterial perfusion.Diabetic foot is diabetes
One of a kind of serious complication, is that diabeticss are disabled, or even lethal major reason, not only cause suffering to patient,
And make which add huge financial burden.World Health Organization (WHO) to the definition of diabetic foot is：Diabeticss due to
Merge neuropathy and various different degrees of peripheral vessel pathological changes and cause lower limb infection, ulcer and（Or）Portion's tissue
Destroy.
Chinese medicine thinks that with the passing of time the pathogenesis of primary disease mainly quenches one's thirst, deficiency of both QI and YIN, passages through which vital energy circulates stasis blocking, hematogenous blockage, and acra loses
Support, damp invasion of lower energizer, pyretic toxicity blood stasis, form BI-syndrome involved the blood vessels, necrosis in addition, specific as follows：Stagnation of blood stasis, venation numbness resistance quench one's thirst with the passing of time, because
Scorching in the deficiency of YIN, cloudy liquid virtual loss, scorching inclined Sheng, the bright Tianjin blood of heat, and pachyemia is caused, blood is viscous, and the not smooth stasis of blood of blood is delayed, or by
In scorching yin-damaging and Qi consuming, deficiency of both QI and YIN is made, be difficult blood is transported, blood is powerless, or due to cloudy liquid virtual loss, deficiency of YIN affecting YANG, yang deficiency cold coagulation,
Blood vessels are lost in warm, can all make hematogenous blockage, form blood stasis.Blood stasis is once form, and because blood vessels numbness hinders, hematogenous blockage causes limb
Especially acra loses foster and forms BI-syndrome involved the blood vessels, necrosis for body local.
The Syndrome Differentiation of Traditional Chinese Medicine of diabetic foot can be divided into blood stasis venation type and extreme noxious heat.Blood stasis venation type, the rule for the treatment of is lived
Blood blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, analgesic therapy granulation promoting.Extreme noxious heat rule for the treatment of heat-clearing and toxic substances removing, the evil gesture of control spreads.
Western medical treatment method is taken in treatment currently for diabetic foot, and therapeutic effect is limited, cannot effect a radical cure this again chronic
PD.Chinese medicine is relaxed due to effect, and few side effects can be effectively treated from root, and being therefore badly in need of one kind can be
Mitigate patient's slight illness, benefiting vital QI and blood, blood circulation promoting and blood stasis dispelling, the Chinese medicine composition of putrefaction-removing granulation-promoting.
Content of the invention
The present invention overcomes the deficiencies in the prior art, technical problem to be solved be for qi-ying deficiency type, blood stasis venation type
Sugared pedopathy patient provide control a kind of treat diabetic foot Chinese medicine composition.
For solving above-mentioned technical problem, the technical solution adopted in the present invention is：A kind of Chinese medicine group for treating diabetic foot
Compound, is prepared from by the raw material of following weight：Ramulus Cinnamomi 10-20 part, Flos Carthami 10-20 part, Herba speranskiae tuberculatae 5-15
Part, Caulis Spatholobi 17-24 part, Fructus Liquidambaris 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-17 part, Olibanum 7-15 part, Myrrha 6-15 part, Pericarpium Zanthoxyli 10-
20 parts.
A kind of described Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：Osmanthus
Branch 12-17 part, Flos Carthami 12-17 part, Herba speranskiae tuberculatae 12-17 part, Caulis Spatholobi 19-22 part, Fructus Liquidambaris 8-11 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 8-13
Part, Olibanum 9-13 part, Myrrha 9-13 part, Pericarpium Zanthoxyli 13-17 part.
A kind of described Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：Osmanthus
15 parts of branch, 15 parts of Flos Carthami, 10 parts of Herba speranskiae tuberculatae, 20 parts of Caulis Spatholobi, 10 parts of Fructus Liquidambaris, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 10 parts of Olibanum,
10 parts of Myrrha, 15 parts of Pericarpium Zanthoxyli.
A kind of preparation method of described Chinese medicine composition for treating diabetic foot, comprises the following steps：By above-mentioned weight
The raw material of part proportioning soaks 15 min, then 30 min of decocting with the clear water of 500 weight portions.
The using method of Chinese medicine composition is to take 300 mL of medicine juice for having decocted, and first fumigates, when water temperature is down to 40 DEG C, is used for
Soak suffering limb.
In the present invention, each Chinese medicine ingredients pharmaceutical characteristic is as follows：
Ramulus Cinnamomi, acrid, sweet, warm.GUIXIN, lung, bladder warp.Sweating expelling pathogenic factors from muscles and skin, promoting the flow of QI-blood by warming the meridian, helps yang transforming qi, flat gas that spins.For wind and cold
Flu, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Flos Carthami, pungent, temperature.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, { note of the ancient Chinese } abdominal mass
Mass in the abdomen, injury from falling down, sore swell and ache curative.
Herba speranskiae tuberculatae, pungent；Warm in nature.Lung；Liver Channel.Expelling wind and removing dampness；Relaxing muscles and tendons to promote blood circulation；Dissipating blood stasis for subsidence of swelling；Removing toxic substances ophthalmalgia.Main air arthralgia chiefly caused by damp pathogen
Bitterly；Muscles and bones contracture；The disturbance of lower legs due to pathogenic cold and dampness；Lumbar strain；Paralysis；Amenorrhea；Eczema scrotum；Sore furuncle poison.
Caulis Spatholobi, taste acrid, sweet, warm.Return liver warp.Promoting circulation of blood and enriching blood, soothing the channels and quicking the network vessels.For amenorrhea, dysmenorrhea, blood deficiency giddy, limb
Body numbness, rheumatic arthralgia.Also radioactive leukocytopenia is controlled.
Fructus Liquidambaris are bitter；Flat；.12 warps.Expelling wind and removing dampness；Soothing the liver active；Diuretic.Main air pain of dampness syndrome；Numb limbs and tense tendons；Brothers
Contracture；Epigastric pain；Amenorrhea；Galactostasiss；Oedema turgor；Eczema.
The Pseudobulbus Bletillae (Rhizoma Bletillae), bitter, sweet, puckery, it is slightly cold.Return lung, liver, stomach.Astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, wound goes out
Blood, sore swollen toxin, chapped skin；Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Olibanum, acrid in the mouth, hardship, temperature.GUIXIN, liver, spleen channel.Promoting blood circulation and stopping pain, detumescence and promoting granulation.For traumatic injury, carbuncle, trusted subordinate
Bitterly, contracture, skin infection diabrosis is not closed up long.The turbid bitter in the mouth of this product gas, irritant to stomach, easily vomiting is caused, stomach weak person use with caution.
Myrrha, bitter, put down.GUIXIN, liver, spleen channel.Scattered blood and relieving pain, detumescence and promoting granulation.Ulcer sore pain, trusted subordinate, all pains of muscles and bones, damage
Blood stasis, external can expelling pus and promoting granulation.
Pericarpium Zanthoxyli, acrid in the mouth, heat, slightly poisonous.Returns spleen, stomach, kidney channel.Warming middle-JIAO, pain relieving, parasite killing.For coldness and pain in the epigastrium, vomit, let out
Rush down, ascarid, eczema itch.
Compatibility parsing of the present invention is as follows：
Monarch drug：It is the medicine for playing primary treatment effect for main disease or main symptom.First of in its efficacy of a drug side of residence, it is indispensable
Medicine.Monarch drug is preferably few, and general only with simply, if the state of an illness is complicated can use two tastes, but monarch drug flavour of a drug are unsuitable excessive, and at most the efficacy of a drug is divided
Dissipate.
The present invention is with Ramulus Cinnamomi, and Flos Carthami is " monarch ", Ramulus Cinnamomi, sweating expelling pathogenic factors from muscles and skin, promoting the flow of QI-blood by warming the meridian, helps yang transforming qi, flat gas that spins；Red
Flower, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Ministerial drug：One is the medicine for aiding in monarch drug to strengthen the main disease for the treatment of or main symptom；Two is to play treatment for simultaneous disease or accompanied symptoms
The medicine of effect.Its efficacy of a drug is less than monarch drug.
The present invention is with Herba speranskiae tuberculatae, Caulis Spatholobi, Fructus Liquidambaris, and the Pseudobulbus Bletillae (Rhizoma Bletillae) is " minister ", Herba speranskiae tuberculatae, relaxing muscles and tendons to promote blood circulation, wind-expelling pain-stopping；
Caulis Spatholobi, enriches blood, promoting blood circulation, dredging collateral；Fructus Liquidambaris, dispelling wind and removing obstruction in the collateral, promoting diuresis to clear away damp pathogen；The Pseudobulbus Bletillae (Rhizoma Bletillae), astringing to arrest bleeding, detumescence and promoting granulation.
Adjuvant drug：Supplementary drug, assists monarch, ministerial drug to strengthen therapeutical effect, or directly treatment minor symptom.
The present invention " is assisted a ruler in governing a country " with Olibanum, Myrrha, Olibanum, regulating qi and activating blood, pain relieving blood stasis dispelling；Myrrha, scattered blood and dissolving stasis, detumescence is fixed
Bitterly.
Make medicine：Guiding drug, can in the side of drawing all medicines with reach disease medicine.
The present invention with Pericarpium Zanthoxyli as " making ", Pericarpium Zanthoxyli, dispelling cold and removing dampness resolving depression sugar foot health be suitable to dialectical category qi-ying deficiency type, blood stasis arteries and veins
Network type person.
Compared with prior art the invention has the advantages that.
Ramulus Cinnamomi in the present invention, sweating expelling pathogenic factors from muscles and skin, promoting the flow of QI-blood by warming the meridian, helps yang transforming qi, flat gas that spins；Flos Carthami, promoting blood circulation to restore menstrual flow, dissipating blood stasis stop
Bitterly；Herba speranskiae tuberculatae, relaxing muscles and tendons to promote blood circulation, wind-expelling pain-stopping；Caulis Spatholobi, enriches blood, promoting blood circulation, dredging collateral；Fructus Liquidambaris, dispelling wind and removing obstruction in the collateral promoting diuresis to clear away damp pathogen；
The Pseudobulbus Bletillae (Rhizoma Bletillae), astringing to arrest bleeding, detumescence and promoting granulation；Olibanum, regulating qi and activating blood, pain relieving blood stasis dispelling；Myrrha, scattered blood and dissolving stasis, subduing swelling and relieving pain；Pericarpium Zanthoxyli, dissipates
Cold dehumidifying resolving depression sugar foot health is suitable to dialectical category qi-ying deficiency type, blood stasis venation type person, and Chinese medicine used all has promoting blood circulation to remove obstruction in the collateral effect,
Improve microangiopathies, and promote the functional rehabilitation of damaged nerve tissue, promote skin epithelial cell growth, expansion of blood vessels increases
Peripheral tissues' blood flow, suppresses platelet aggregation, reduces blood viscosity, increases the microcirculatory perfusion of peripheral nerve tissue, improves and lacks
Blood, the effect of anaerobic condition.
Inventive formulation is unique, processing technology is simple and convenient easy, with significant curative effect, be primarily adapted for use in qi-ying deficiency type,
The sugared pedopathy patient of blood stasis venation type.The work(such as heat-clearing and toxic substances removing that Chinese medicine composition of the present invention is used, blood circulation promoting and blood stasis dispelling, dredge the meridian passage
Effect medical material, is reached by synergism and is effectively improved wound surface microcirculation, promote slough to come off, and is accelerated inflammation absorption, is promoted
Granulation tissue and epithelial tissue growth and the effect of wound healing, improve the quality of life of patient, and safety are higher.
Specific embodiment
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：15 parts of Ramulus Cinnamomi, red
15 parts are spent, 10 parts of Herba speranskiae tuberculatae, 20 parts of Caulis Spatholobi, 10 parts of Fructus Liquidambaris, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 10 parts of Olibanum, 10 parts of Myrrha,
15 parts of Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine composition of the treatment diabetic foot, comprises the following steps：By above-mentioned weight
Raw material soak 15 min, then 30 min of decocting with the clear water of 500 weight portions.
The using method of Chinese medicine composition is to take the 300 m L of medicine juice for having decocted, and first fumigates, and when water temperature is down to 40 DEG C, uses
In immersion suffering limb.
Embodiment 2
A kind of Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：10 parts of Ramulus Cinnamomi, red
20 parts are spent, 5 parts of Herba speranskiae tuberculatae, 24 parts of Caulis Spatholobi, 5 parts of Fructus Liquidambaris, 17 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 7 parts of Olibanum, 15 parts of Myrrha, Pericarpium Zanthoxyli 10
Part.
The preparation method of the Chinese medicine composition of the treatment diabetic foot, comprises the following steps：By above-mentioned weight
Raw material soak 15 min, then 30 min of decocting with the clear water of 500 weight portions.
Embodiment 3
A kind of Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：20 parts of Ramulus Cinnamomi, red
10 parts are spent, 15 parts of Herba speranskiae tuberculatae, 17 parts of Caulis Spatholobi, 15 parts of Fructus Liquidambaris, 6 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Olibanum, 6 parts of Myrrha, Pericarpium Zanthoxyli 20
Part.
The preparation method of the Chinese medicine composition of the treatment diabetic foot, comprises the following steps：By above-mentioned weight
Raw material soak 15 min, then 30 min of decocting with the clear water of 500 weight portions.
Embodiment 4
A kind of Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：12 parts of Ramulus Cinnamomi, red
17 parts are spent, 12 parts of Herba speranskiae tuberculatae, 22 parts of Caulis Spatholobi, 8 parts of Fructus Liquidambaris, 13 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 9 parts of Olibanum, 13 parts of Myrrha, Pericarpium Zanthoxyli 13
Part.
The preparation method of the Chinese medicine composition of the treatment diabetic foot, comprises the following steps：By above-mentioned weight
Raw material soak 15 min, then 30 min of decocting with the clear water of 500 weight portions.
Embodiment 5
A kind of Chinese medicine composition for treating diabetic foot, is prepared from by the raw material of following weight：17 parts of Ramulus Cinnamomi, Flos Carthami
12 parts, 17 parts of Herba speranskiae tuberculatae, 19 parts of Caulis Spatholobi, 11 parts of Fructus Liquidambaris, 8 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 13 parts of Olibanum, 9 parts of Myrrha, 17 parts of Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine composition of the treatment diabetic foot, comprises the following steps：By above-mentioned weight
Raw material soak 15 min, then 30 min of decocting with the clear water of 500 weight portions.
Present invention using effect clinically：
Physical data is selected 140 to be our hospital's Inpatients and is the sugared pedopathy patient of blood stasis venation type, random point
For two groups.Treatment group 80, man 50, female 30；The oldest 68 years old, minimum 37 years old, average (45.0 ±
10.2) year；The course of disease is most long 18 years, most short 2 years, average (7.0 ± 2.6) year；Fasting glucose (6.5 ± 2.3)
Mmol/L, after the meal 2 h blood glucose (13.1 ± 3.8) mmol/L.To organizing 60, man 35, female 25；The oldest
66 years old, minimum 38 years old, average (44.2 ± 10.2) year；The course of disease is most long 16 years, most short 3 years, average (7.0 ± 2.4)
Year；Fasting glucose (5.5 ± 2.5) mmol/L, after the meal 2 h blood glucose (10.9 ± 3.5) mmol/L.Two groups of physical data ratios
Compared with no significant difference (P ＞ 0.05), with comparability.
Two groups of patients all apply 8 U of Isophane Protamine Biosynthetic Human Insulin Injection daily 21 after being admitted to hospital:00 is subcutaneous
Injection.
Treatment group：The traditional Chinese medicine composition for treating for giving the embodiment of the present invention 1 to prepare, first fumigates, and when water temperature is down to 40 DEG C, uses
In soaking suffering limb, daily 1 time, 30 min every time.
Matched group：Pericarpium Zanthoxyli is given to decoct 30 min of blistering foot.
The course for the treatment of：Two groups are all treated 4 weeks.
Efficacy evaluation：After treatment, a situation arises for observation wound healing situation and untoward reaction.Criterion is with reference to Chinese medicine
Clinical Researches of New Drugs guideline standard [4]：Clinical cure is disappeared for local swelling, and skin color recovers normal, ulcer surface
Heal completely；Effective is that local swelling and skin color improve, and ulcer surface reduces more than 70%；It is effectively local swelling and skin
Skin color perfecting, ulcer surface reduces more than 30%；Invalid for not reaching efficiency index.Total effective rate is cure rate, obvious effective rate
With effective percentage sum.
Therapeutic outcome：Treatment group cures 65, effective 6, effective 8, invalid 1, and cure rate is
81.25%, total effective rate is 98.75%, healing time 10～24 days.Matched group cures 5, effective 5, has
Effect 2；Invalid 48, it is 20% that cure rate is 8.33%, total effective rate, and two groups of cure rates, total effective rates compare, difference
All there is significant (P<0.01).
The above results explanation present invention has significant curative effect for the sugared pedopathy patient of qi-ying deficiency type, blood stasis venation type.
The present invention can with others without prejudice to the spirit or essential characteristics of the present invention concrete form summarizing.Therefore, no
By from the point of view of which point, the embodiment above of the present invention can only all be considered the description of the invention and can not limit invention,
Claims indicate the scope of the present invention, and the scope of the present invention is not pointed out in above-mentioned explanation, therefore, with the present invention
The suitable implication and scope of claims in any change, be all considered as being included within the scope of the claims.
Claims (5)
1. a kind of Chinese medicine composition for treating diabetic foot, it is characterised in that be prepared from by the raw material of following weight：
Ramulus Cinnamomi 10-20 part, Flos Carthami 10-20 part, Herba speranskiae tuberculatae 5-15 part, Caulis Spatholobi 17-24 part, Fructus Liquidambaris 5-15 part, the Pseudobulbus Bletillae (Rhizoma Bletillae)
6-17 part, Olibanum 7-15 part, Myrrha 6-15 part, Pericarpium Zanthoxyli 10-20 part.
2. a kind of Chinese medicine composition for treating diabetic foot according to claim 1, it is characterised in that by following weight portion
The raw material of proportioning is prepared from：Ramulus Cinnamomi 12-17 part, Flos Carthami 12-17 part, Herba speranskiae tuberculatae 12-17 part, Caulis Spatholobi 19-22 part,
Fructus Liquidambaris 8-11 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 8-13 part, Olibanum 9-13 part, Myrrha 9-13 part, Pericarpium Zanthoxyli 13-17 part.
3. a kind of Chinese medicine composition for treating diabetic foot according to claim 1, it is characterised in that by following weight portion
The raw material of proportioning is prepared from：15 parts of Ramulus Cinnamomi, 15 parts of Flos Carthami, 10 parts of Herba speranskiae tuberculatae, 20 parts of Caulis Spatholobi, Fructus Liquidambaris 10
Part, 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 10 parts of Olibanum, 10 parts of Myrrha, 15 parts of Pericarpium Zanthoxyli.
4. a kind of preparation method of Chinese medicine composition for treating diabetic foot according to claim 1, it is characterised in that bag
Include following steps：The raw material of above-mentioned weight is soaked 15 min, then 30 min of decocting with the clear water of 500 weight portions.
5. according to claim 4 treatment diabetic foot Chinese medicine composition preparation method, it is characterised in that Chinese medicine group
The using method of compound is to take 300 mL of medicine juice for having decocted, and first fumigates, when water temperature is down to 40 DEG C, for soaking suffering limb.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109529022A (en) * | 2019-01-05 | 2019-03-29 | 江苏美德愈医疗科技有限公司 | A kind of diabetic foot wound externally applied drug and its application method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552454A (en) * | 2010-12-16 | 2012-07-11 | 王桂菊 | Traditional Chinese medicine for curing diabetic foot |
| CN102846824A (en) * | 2012-08-28 | 2013-01-02 | 杨高林 | Traditional Chinese medicinal composition for treating cold dampness blood stasis blocking channel type diabetic feet, and its preparation method |
-
2016
- 2016-12-21 CN CN201611188077.1A patent/CN106421410A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552454A (en) * | 2010-12-16 | 2012-07-11 | 王桂菊 | Traditional Chinese medicine for curing diabetic foot |
| CN102846824A (en) * | 2012-08-28 | 2013-01-02 | 杨高林 | Traditional Chinese medicinal composition for treating cold dampness blood stasis blocking channel type diabetic feet, and its preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109529022A (en) * | 2019-01-05 | 2019-03-29 | 江苏美德愈医疗科技有限公司 | A kind of diabetic foot wound externally applied drug and its application method |
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Application publication date: 20170222 |