CN105853580A

CN105853580A - Traditional Chinese medicine composition for treating refractory edema

Info

Publication number: CN105853580A
Application number: CN201610456900.6A
Authority: CN
Inventors: 姜兴鹏; 胡波
Original assignee: Chongqing Three Gorges Medical College Affiliated Hospital
Current assignee: Chongqing Three Gorges Medical College Affiliated Hospital
Priority date: 2016-06-21
Filing date: 2016-06-21
Publication date: 2016-08-17

Abstract

The invention discloses a traditional Chinese medicine composition for treating refractory edema. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 parts of radix astragali, 2-4 parts of peach kernel, 2-4 parts of safflower, 2-4 parts of ligusticum wallichii, 1-2 parts of radix paeoniae alba, 3-6 parts of angelica sinensis, 1-4 parts of leech, 2-6 parts of ginseng, 2-6 parts of radix rehmanniae, 2-6 parts of radix rehmanniae preparata, 2-4 parts of rhizoma atractylodis macrocephalae, 2-4 parts of poria cocos, 1-2 parts of akebia stem, 2-4 parts of plantain seed and 1-2 parts of liquorice. By adopting the methods of tonifying qi, activating blood, dredging collaterals, invigorating the spleen, tonifying the kidneys and excreting water and combining a creative new formula, the effects of eliminating stagnated pathogen, invigorating the spleen and kidneys in transportation and diminishing edema can be realized; and the effective rate is over 93.3%.

Description

The Chinese medicine composition for the treatment of refractory edema

Technical field

The present invention relates to the field of Chinese medicines, particularly to the Chinese medicine composition for the treatment of refractory edema.

Background technology

Refractory edema, is also called Refractory Edema, sees that delay is not moved back, and swollen gesture weight differs, extremity Or anasarca, based on lower limb, the dermal ecchymosis, waist twinge, or companion's hematuria, purplish tongue is dark, and tongue is white, Deep-thready pulse is puckery；It is more common in nephrotic syndrome, thrombotic deep phlebitis, chronic heart failure, tumor clinically Patient, Hemiplegic Patients after radiotherapy.In a word, treatment refractory edema in Chinese and Western all quite feels thorny.At present, Traditional Chinese medical science treat from blood stasis treatment refractory edema, obtains certain curative effect.Traditional Chinese medical science decoction for the treatment nephrotic syndrome, blood The refractory edema document reports such as bolt deep phlebitis, chronic heart failure are more, with spleen invigorating, diuretic, benefit Kidney, activating blood circulation method are main, mainly select Zhen Wu Tang, Decoction for strengthening the Spleen-Yang, gas a decotion of Chinese medicine to be taken cold, heart tonifying kidney tonifying detumescence Tang Dengfang to add to invigorate blood circulation and dispel Stasis of blood medicineization cuts out treatment.But, refractory edema document caused after apoplectic hemiplegia, tumor radiotherapy etc. is reported relatively Few, with inrigorating qi and promoting blood circulation Promoting diuresis, main selection BUYANG HUANWU TANG is the treatment of main addition or subtraction of changes.But, apoplexy The caused refractory edema such as after hemiplegia, tumor radiotherapy, medical record is more clinically, and current treatment way is in spy The rope stage.Refractory edema caused by these diseases, its main pathogenesis is " deficiency in origin and excess in superficiality ", and " deficiency in origin " is many Because the deficiency of vital energy is main, and it is not smooth to cause QI-blood circulation, and the pathogen usually intruding into collateral in protracted disease hyperamization stasis of blood, so that body fluid can not normal defeated cloth Whole body, water liquid flooding is sent out in skin excessively as edema；" mark is real ", based on the wet stagnation of blood stasis of water, they are The pathological product of visceral dysfunction, is again to cause spleen to be suffered from a deficiency of the kidney damage, the state of an illness develop further important pathogenic because of Element.The two influences each other, and with the passing of time water retention must cause blood stasis due to qi deficiency, and blood stasis hinders gasification cause edema difficulty to disappear.

Summary of the invention

In view of this, it is an object of the invention to provide a kind of Chinese medicine composition treating refractory edema, adopt With QI invigorating, invigorate blood circulation, dredging collateral, spleen invigorating, the kidney invigorating, all methods of diuretic, share the new side of initiative, as if can old fall remove, The strong fortune of spleen kidney, edema disappears.

The Chinese medicine composition of the treatment refractory edema of the present invention, described traditional Chinese medicine composite is wrapped by weight Include following components:

Radix Astragali 10-20 part, Semen Persicae 2-4 part, Flos Carthami 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Paeoniae Alba 1-2 part, when Return 3-6 part, Hirudo 1-4 part, Radix Ginseng 2-6 part, Radix Rehmanniae 2-6 part, Radix Rehmanniae Preparata 2-6 part, Rhizoma Atractylodis Macrocephalae 2-4 part, Poria 2-4 part, Caulis Akebiae 1-2 part, Herba Plantaginis core 2-4 part, Radix Glycyrrhizae 1-2 part；

Further, described traditional Chinese medicine composite includes following components by weight:

The Radix Astragali 15 parts, 3 parts of Semen Persicae, 3 parts of Flos Carthami, Rhizoma Chuanxiong 3 parts, the Radix Paeoniae Alba 1.5 parts, Radix Angelicae Sinensis 4 parts, Hirudo 3 parts, Radix Ginseng 3 parts, 3 parts of the Radix Rehmanniae, 3 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria, Caulis Akebiae 1.5 Part, Herba Plantaginis core 3 parts, 1.5 parts of Radix Glycyrrhizae；

Further, said composition can add the carrier that can accept in medical science or bromatology or health care conduct and learning and makes Preparation；

Further, said composition can add one or more for the Chinese medicine improving or treating accompanied symptoms.

Beneficial effects of the present invention: the Chinese medicine composition of the treatment refractory edema of the present invention, employing QI invigorating, Invigorate blood circulation, dredging collateral, spleen invigorating, the kidney invigorating, all methods of diuretic, share the new side of initiative, as if can old fall remove, spleen kidney is good for Fortune, edema disappears.Refractory edema is mainly in middle-older patient, how to cause QI-blood circulation freely because of the deficiency of vital energy, The for a long time hyperamization stasis of blood so that body fluid can not normal defeated cloth whole body, water liquid flooding is sent out as edema in skin excessively.We Reuse the Radix Astragali and ginseng qi-tonifying, gas row then blood, gas row then Tianjin row, gas row then humidifying；Water distribution trematodiasis, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, the Radix Paeoniae Alba, with ginseng stilbene phase 5, benefiting QI for activating blood circulation, disperse blood stasis and dredge collateral, nourish blood tissue regeneration promoting, and the stasis of blood goes network to lead to, Body fluid obtains cloth, then edema is from disappearing；Join the Rhizoma Atractylodis Macrocephalae, Poria, with ginseng stilbene invigorating spleen for diuresis；Join the Radix Rehmanniae, Radix Rehmanniae Preparata, with GUISHAO 5 nourishes blood tissue regeneration promoting mutually, and the anti-stasis of blood just is going to hinder, with the 5 spleen kidney giving young employees remedial-courses in general knowledge and vocational skills mutually of art Siberian cocklebur, " spleen controlling the water circulation " and " the main water of kidney " Function must be answered, and the defeated cloth of body fluid is normal, and water goes swollen disappearing；Joining Caulis Akebiae, Herba Plantaginis core, promoting diuresis to eliminate damp pathogen is subsided a swelling.Quan Fang Play benefiting QI for activating blood circulation altogether, strengthening spleen, tonifying kidney, the merit of inducing diuresis to remove edema, giving consideration to both the incidental and fundamental, the stasis of blood removes Tianjin cloth, edema from.

The Radix Astragali: the Radix Astragali can promote organism metabolism, resisting fatigue, promotion serum and the renewal of hepatic protein；Have bright Aobvious diuresis, can eliminate Jishengshenqiwan urine protein；Anemia animal phenomenon can be improved；Height blood can be risen Sugar, reduces hyperglycemia；Can excited breathe；Can strengthen and regulation body's immunity, interferon system is had Facilitation, can improve the premunition of body；The multiple viral institute such as infected by influenza cytopathogenic effect has slightly Inhibitory action, the protected effect of influenza virus infected；There is wide antibacterial action；The Radix Astragali is carefully During born of the same parents cultivate, can make cell number showed increased, cell growth is vigorous, life；Myocardial contraction can be strengthened Power, protects cardiovascular system, arrhythmia, coronary artery dilator and peripheral blood vessel, reduces blood pressure, energy Reduce platelet adhesion power, reduce thrombosis；Also have blood fat reducing, defying age, anti-hypoxia, radioprotective, The effect such as protect the liver.

Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.

Flos Carthami: warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, Lump in the abdomen mass in the abdomen, traumatic injury.

Rhizoma Chuanxiong: activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain, control headache and revolve dizzy, costalgia abdomen pain, amenorrhea, difficulty The diseases such as product, ulcer sores.

The Radix Paeoniae Alba: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For dizziness of having a headache, hypochondriac pain, stomachache, extremity Spasm and pain, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Radix Angelicae Sinensis: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizziness cardiopalmus, menstruation not Tune, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Hirudo: removing blood stasis, removing blood stasis, stimulates the menstrual flow.Controlling blood-retention, lump in the abdomen, accumulation, women's amenorrhea, blood stasis becomes consumptive disease, falls Flutter damage, mesh also pain, nebula.

Radix Ginseng: the fleshy tap root of Radix Ginseng is famous strong tonic, it is adaptable to adjust blood pressure, recover cardiac function, The disease such as neurasthenia and physical weakness, also eliminate the phlegm, stomach invigorating, diuresis, the effect such as excitement.

The Radix Rehmanniae: the power of YIN nourishing is the most inferior, but clearing away heat and promoting production of body fluid, the power of cooling blood for hemostasis is stronger.

Radix Rehmanniae Preparata: have YIN nourishing effect of enriching blood, can be used for blood deficiency and yellow complexion, dizziness, palpitation and insomnia, menoxenia, The diseases such as metrorrhagia.

The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive. For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, Stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.

Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool Have loose bowels, irritability, palpitation with fear insomnia.

Caulis Akebiae: clearing away heat and promoting diuresis；Blood circulation and channel invigorating.Main red urine is red；Stranguria with turbid discharge；Edema；Irritable feverish sensation in the chest；Larynx larynx aches Bitterly；Aphtha of the mouth and tongue；Rheumatic arthralgia；Galactostasis；Amenorrhea；Dysmenorrhea.

Herba Plantaginis core is Plantaginaceae plant Herba Plantaginis or the dry mature seed of Plantago depressa Willd.For edema distension, heat Drench puckery pain, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.

Radix Glycyrrhizae: treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, long muscle, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide for a long time Prolong life.Life pathogenic fire purging heat, ripe using dissipates exterior cold, goes pharyngalgia, and evil removing is hot, slow healthy energy, yin nourishing blood, tonifying the spleen and stomach, Lung moistening.

Detailed description of the invention

Embodiment one

The Chinese medicine composition of the treatment refractory edema of the present embodiment, described traditional Chinese medicine composite is by weight Including following components:

The Radix Astragali 10 parts, 2 parts of Semen Persicae, 2 parts of Flos Carthami, Rhizoma Chuanxiong 2 parts, the Radix Paeoniae Alba 1 part, Radix Angelicae Sinensis 3 parts, water Trematodiasis 1 part, Radix Ginseng 2 parts, 2 parts of the Radix Rehmanniae, 2 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 2 parts, 2 parts of Poria, Caulis Akebiae 1 part, Herba Plantaginis core 2 parts, 1 part of Radix Glycyrrhizae.

Embodiment two

The Radix Astragali 20 parts, 4 parts of Semen Persicae, 4 parts of Flos Carthami, Rhizoma Chuanxiong 4 parts, the Radix Paeoniae Alba 2 parts, Radix Angelicae Sinensis 6 parts, water Trematodiasis 4 parts, Radix Ginseng 6 parts, 6 parts of the Radix Rehmanniae, 6 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 4 parts, 4 parts of Poria, Caulis Akebiae 2 parts, Herba Plantaginis core 4 parts, 2 parts of Radix Glycyrrhizae.

Embodiment three

The Radix Astragali 10 parts, 4 parts of Semen Persicae, 2 parts of Flos Carthami, Rhizoma Chuanxiong 4 parts, the Radix Paeoniae Alba 1 part, Radix Angelicae Sinensis 6 parts, water Trematodiasis 1 part, Radix Ginseng 6 parts, 2 parts of the Radix Rehmanniae, 6 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 2 parts, 4 parts of Poria, Caulis Akebiae 1 part, Herba Plantaginis core 4 parts, 1 part of Radix Glycyrrhizae.

Embodiment four

The Radix Astragali 20 parts, 2 parts of Semen Persicae, 4 parts of Flos Carthami, Rhizoma Chuanxiong 2 parts, the Radix Paeoniae Alba 2 parts, Radix Angelicae Sinensis 3 parts, water Trematodiasis 4 parts, Radix Ginseng 2 parts, 6 parts of the Radix Rehmanniae, 2 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 4 parts, 2 parts of Poria, Caulis Akebiae 2 parts, Herba Plantaginis core 2 parts, 2 parts of Radix Glycyrrhizae.

Embodiment five

The Radix Astragali 15 parts, 4 parts of Semen Persicae, 2 parts of Flos Carthami, Rhizoma Chuanxiong 3 parts, the Radix Paeoniae Alba 1 part, Radix Angelicae Sinensis 6 parts, water Trematodiasis 2 parts, Radix Ginseng 2 parts, 6 parts of the Radix Rehmanniae, 4 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 2 parts, 4 parts of Poria, Caulis Akebiae 1.5 parts, Herba Plantaginis core 2 parts, 2 parts of Radix Glycyrrhizae.

Embodiment six

The Radix Astragali 15 parts, 3 parts of Semen Persicae, 3 parts of Flos Carthami, Rhizoma Chuanxiong 3 parts, the Radix Paeoniae Alba 1.5 parts, Radix Angelicae Sinensis 4 parts, Hirudo 3 parts, Radix Ginseng 3 parts, 3 parts of the Radix Rehmanniae, 3 parts of Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae 3 parts, 3 parts of Poria, Caulis Akebiae 1.5 Part, Herba Plantaginis core 3 parts, 1.5 parts of Radix Glycyrrhizae.

The Chinese medicine composition of the treatment refractory edema of above-described embodiment can add medical science or bromatology or health care The carrier that can accept in conduct and learning makes preparation, it is possible to be decocted in water for oral dose.

The Chinese medicine composition of the treatment refractory edema of above-described embodiment, said composition can add one or more For improving or treat the Chinese medicine of accompanied symptoms；As the Herba Leonuri of 1-3 part, 1-3 part Radix Salviae Miltiorrhizae, 1-2 part can be added Radix Aconiti Lateralis Preparata, 0.5-1 part Rhizoma Imperatae blood circulation promoting and blood stasis dispelling, warming YANG to promote diuresis；Also can add 1-2 part Cortex Eucommiae, 1-2 part Fructus Lycii, 1-2 part Rhizoma Zingiberis Recens is with warming the kidney and strengthening the spleen；Also the Ramulus Cinnamomi of 1-2 part, Ba Ji, Pericarpium Arecae, the Radix Aucklandiae, Semen Arecae, thickness can be added Piao, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum etc are to help activating QI, it is to avoid the fraud being jammed, be commonly incorporated into during such as double diseases caused by exogenous pathogenic factor 1-2 part Herba Ephedrae, Semen Armeniacae Amarum, Radix Platycodonis, Periostracum Cicadae etc. are in order to lung qi dispersing.

Experimental example

1, experimental data

Accept observation patient 30 example, the maleest 16 examples, female 14 example for medical treatment；The oldest person 85 years old, the age is Little person 46 years old.

2, efficacy assessment standard:

Cure: edema disappears, and each index of correlation reaches normal level, and sign is improved completely, and patient is without any Bad sensation.

Effective: edema disappears substantially, each index of correlation is improved the most substantially close to normal level, sign, suffers from Person is substantially without any bad sensation.

Effective: edema is improved, and each index of correlation reaches and makes moderate progress, and sign has improvement.

Invalid: edema is unchanged, each index of correlation does not all change, and sign is without improving.

3, therapeutic effect: after using the Chinese medicine decoction 2-3 agent of embodiment six, then take the powder of embodiment six After 1-2 agent, cure 18 examples, effective 8 examples, effective 3 examples, invalid 2 examples, cure rate 60%, the most effectively Rate 93.3%.

4, typical case's case

Case 1: Chen, female, 85 years old, apoplexy and senile dementia several years, owing to long-term bed was to double lower limb water The swollen several months, it is clearly better through taking invented party 2 pairs (6 days), then takes the powder 2 doses recovery from illness of embodiment one. Afterwards by this side treatment apoplectic hemiplegia and unknown cause edema 30 many cases, the most effective.

Case 2: Wang, man, 61 years old, apoplexy to left half body movable unfavorable March, upper left lower limbs edema January, Channel therapeutic effect does not shows, after taking 3 doses of the water preparation of embodiment two and the prescription powder 1 dose of embodiment three Edema is fully recovered.

Finally illustrate, above example only in order to technical scheme to be described and unrestricted, although With reference to preferred embodiment, the present invention is described in detail, it will be understood by those within the art that, Technical scheme can be modified or equivalent, without deviating from technical solution of the present invention Objective and scope, it all should be contained in the middle of scope of the presently claimed invention.

Claims

1. the Chinese medicine composition treating refractory edema, it is characterised in that: described traditional Chinese medicine composite Include following components by weight:

Radix Astragali 10-20 part, Semen Persicae 2-4 part, Flos Carthami 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Paeoniae Alba 1-2 part, when Return 3-6 part, Hirudo 1-4 part, Radix Ginseng 2-6 part, Radix Rehmanniae 2-6 part, Radix Rehmanniae Preparata 2-6 part, Rhizoma Atractylodis Macrocephalae 2-4 part, Poria 2-4 part, Caulis Akebiae 1-2 part, Herba Plantaginis core 2-4 part, Radix Glycyrrhizae 1-2 part.

The Chinese medicine composition for the treatment of refractory edema the most according to claim 1, it is characterised in that: institute State traditional Chinese medicine composite and include following components by weight:

3. according to the Chinese medicine composition of the treatment refractory edema described in any one of claim 1-2, its feature It is: said composition can add the carrier that can accept in medical science or bromatology or health care conduct and learning and make preparation.

4. according to the Chinese medicine composition of the treatment refractory edema described in any one of claim 1-2, its feature It is: said composition can add one or more for the Chinese medicine improving or treating accompanied symptoms.