CN102824576B - Traditional Chinese medicinal composition for treating psoriasis and preparation method thereof - Google Patents

Traditional Chinese medicinal composition for treating psoriasis and preparation method thereof Download PDF

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CN102824576B
CN102824576B CN 201110160046 CN201110160046A CN102824576B CN 102824576 B CN102824576 B CN 102824576B CN 201110160046 CN201110160046 CN 201110160046 CN 201110160046 A CN201110160046 A CN 201110160046A CN 102824576 B CN102824576 B CN 102824576B
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张翕如
王海斌
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王海斌
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating psoriasis and a preparation method thereof. The composition comprises the following drug materials of: by weight, 20-30 parts of Smilax glabra, 15-20 parts of root of large-flowered skullcap, 20-25 parts of Asarum Herb, 15-20 parts of coptis, 10-15 parts of rheum officinale, 5-10 parts of star anise, 20-25 parts of Polyporus umbellatus and 15-20 parts of licorice. According to the preparation method, the above drug materials are weighed; each ingredient is crushed into a powder of 80-120 meshes; then the powders are uniformly mixed and are made into capsules, pills or powders according to a conventional method. The traditional Chinese medicinal composition provided by the invention has effects of adjusting human balance, eliminating siltation, removing blood stasis, expelling wind and dissipating cold, stopping endogenous wind, alleviating convulsion, relaxing vein and relieving pain, and has advantages of short treatment course and definite therapeutic effects. Cure rate of the composition for common psoriasis reaches up to 85.3%, and its total effective rate reaches 100%.

Description

Treat psoriasic Chinese medicine composition and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of psoriasic Chinese medicine composition and preparation method thereof for the treatment of.
Background technology
" psoriasis " belongs to commonly encountered diseases, frequently-occurring disease, the distribution position is different, state of an illness weight difference is very large, psoriasic type generally can be divided into multiple, modal is the homeliness type psoriasis, show as erythra and generally occur in scalp, trunk and extremity, occur red pimple on skin, expansion is fused into patch or speckle gradually, there are thicker silvery white phosphorus bits on the surface, out-of-shape, some skin lesion are more, are starlike over the sky, the squama pull-up falls behind, wipe gently scurf off and can see the red film of one deck, strike off red film and can see little petechia, medically make again the sieve shape hemorrhage.Other psoriasis type is just like pustule type psoriasis, psoriasis arthropathica, erythrodermic psoriasis etc., and these also happen occasionally, but are not too common.
It is multiple that psoriasic pathogenic factor mainly contains heredity, immunologic function disorder, direct stimulation, trauma infection contamination etc. at present, but there is no so far clearly final conclusion.Clinically mainly with cell toxicant kind anti-cancer drugs such as aminopterin, ethyliminum, bimolane, cyclophosphamide, and the hormone medicines treatments such as dexamethasone, prednisone, betamethasone and import injection, triamcinolone.The various preparations of above medicine and preparation thereof though with afterwards short run effect being arranged, control rear easy recurrence, often are difficult to thorough healing.How to allow the psoriatic break away from the puzzlement of the serious illness, make the thorough rehabilitation of patient, be the problem that medical circle is paid close attention to always.
Summary of the invention
The object of the present invention is to provide a kind of psoriasic Chinese medicine composition for the treatment of, utilize said composition treatment psoriasis short treating period, determined curative effect is with rear difficult recurrence.
The technical scheme that the present invention takes: a kind ofly treat psoriasic Chinese medicine composition, raw material medicaments in part by weight is: Rhizoma Smilacis Glabrae 20-30 part, Radix Scutellariae 15-20 part, Herba Asari 20-25 part, Rhizoma Coptidis 15-20 part, Radix Et Rhizoma Rhei 10-15 part, anistree 5-10 part, Polyporus 20-25 part, Radix Glycyrrhizae 15-20 part.
In described Chinese medicine composition, Rhizoma Smilacis Glabrae 24 grams, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anistree 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.
The preparation method of described Chinese medicine composition takes each crude drug, and each component is ground into 80~120 purpose powder, and then mix homogeneously, make capsule, pill or powder according to a conventional method.
Pharmacology analysis:The present invention is that the inventor is according to oneself clinical experience for many years, get in conjunction with motherland's Chinese medicine marrow dialectical prescription, because psoriasis is damp and hot attacking due to the skin, the present invention is take heat-clearing and toxic substances removing, the cold expelling that induces sweat, expelling wind and removing dampness, reducing swelling and alleviating pain as purpose, adjust total balance of the body, eliminate alluvial, improve total balance of the body, improve skin functional recovery ability, utilize the mutual synergism between medicine, control psoriasic expansion and spread, reaching the effect for the treatment of both the principal and secondary aspects of a disease, reaching at last the purpose of radical cure.
In crude drug, Rhizoma Smilacis Glabrae: the property slightly sweet flavor is flat; Return liver, stomach warp, detoxifcation, dehumidifying, sharp joint; Control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, furuncle, carbuncle, scrofula.Radix Scutellariae: nature and flavor are bitter, and are cold, return lung, gallbladder, spleen, large intestine, small intestine meridian; Cure mainly heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive; Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Herba Asari: nature and flavor are hot, warm; Return lung, kidney channel, cure mainly and dispel the wind, cold expelling, row water is had one's ideas straightened out; Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Rhizoma Coptidis: nature and flavor are bitter, cold; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication; Be used for cold and heat and tie mutually, damp and hot middle resistance, feeling of fullness vomiting.Radix Et Rhizoma Rhei: nature and flavor are bitter, cold; Return spleen, stomach, large intestine, liver, pericardium channel; Cure mainly purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Anistree: nature and flavor are hot, and are sweet, temperature; Be included into spleen, kidney channel; Warming YANG, cold expelling is regulated the flow of vital energy, sterilization; Control the invasion by pathogenic cold vomiting, colic of cold type stomachache, lumbago due to renal deficiency, dried, beriberi caused by pathogenic damp.Polyporus: the property slightly sweet flavor is flat; Return spleen, kidney, urinary bladder channel; Dysuria is controlled in the diuresis eliminating dampness by diuresis, the edema distension, and beriberi is had loose bowels, pouring, turbid, leukorrhagia.Radix Glycyrrhizae: nature and flavor are sweet, and are flat; Be included into spleen, stomach, lung meridian; With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.
Using method: Chinese medicine composition of the present invention is made capsule, and 3 times on the one, each 2,2 months is a course for the treatment of, and every capsules contains effective composition 0.3g, and other dosage forms can be taken with reference to this dosage.
Positive beneficial effect of the present invention:
(1) Chinese medicine composition of the present invention is on the basis of secret prescription handed down in the family from generation to generation, inheriting tradition medical science elite, in conjunction with character of traditional Chinese medicine and pathogeny, screen by research for many years, have an adjustment total balance of the body, eliminate alluvial, the effect of removing blood stasis eliminating stagnation, expelling wind and cold, relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, curing psoriasis is had advantages of short treating period, determined curative effect, and up to 85.3%, total effective rate reaches 100% to common psoriasic cure rate.
(2) curative effect of medication of the present invention is lasting, and short treating period, instant effect are difficult for recurrence after curing, and has changed in the past that medicine is difficult to effect a radical cure this sick difficult problem, and method for making is simple, is worth applying clinically.
(3) drug use safety of the present invention, without any side effects, cost is low, and is easy to use, and the patient spends few, has greatly reduced patient's financial burden.
The curative effect statistics:In recent years in 278 routine patients for the treatment of, male 158 examples wherein, female's 120 examples, age distribution is at 20 ~ 75 years old, and between the course of disease 1 year-15 years, the overwhelming majority is the homeliness type psoriasis, accounts for 246 examples.In 278 routine patients, the case of fully recovering through treatment is 237 examples, accounts for 85.3%; The produce effects case is 19 examples, accounts for 6.8%, and the improvement case is 22 examples, accounts for 7.9%, total effective rate 100%.
Efficacy assessment standard:
Recovery from illness: the skin lesion symptoms such as red pimple and speckle, squamous silver bits, shinny thin film, petechial hemorrhage, pustule all disappear, the arthropathy of getting involved, pain disappearance, activity freely, other conscious Signs all disappears.
Produce effects: the skin lesion symptoms such as red pimple, squamous silver bits, shinny thin film, petechial hemorrhage, pustule etc. obviously disappear more than 70%, and the arthropathy of getting involved returns to normally substantially, and pain obviously alleviates, and mobility significantly strengthens, and other conscious Signs obviously disappears.
Take a turn for the better: the skin lesion resolution of symptoms such as red pimple, silver bits, shinny thin film, petechial hemorrhage, pustule are more than 50%, and the arthropathy of getting involved, pain alleviate to some extent, can do the activity of bending and stretching by a small margin, and other conscious Signs alleviates to some extent.
Invalid: the skin lesion symptoms such as red pimple, silver bits, shinny thin film, petechial hemorrhage, pustule are without obviously disappearing, and the arthropathy of getting involved, pain are unchanged, and activity is still limited, and other conscious Signs is unchanged.
Model case:
Case 1: Lee so-and-so, man, 55 years old.Examine in April, 2005, readme before 4 years extremity, trunk play tinea, the surface has silvery white phosphorus bits to come off, out-of-shape, the red pruritus of color, striking off red film has little petechia.Be diagnosed as the homeliness type psoriasis.Take the capsule of embodiment 1, treat after 3 months, whole body silvery white phosphorus bits disappear, pruritus no longer, and skin smooth, recovery from illness, after treatment 1 month again, follow up a case by regular visits to so far recurrence subsequently.
Case 2: Zhu, man, 65 years old.In JIUYUE, 2006 is examined, and readme got psoriasis 8 years, began oneself and paid no attention to, occur red pimple on extremity skin, there are thicker silvery white phosphorus bits, out-of-shape in the surface, skin lesion is more, is starlike over the sky, and squama pull-up backwardness can be seen the red film of one deck, strike off red diaphragm screen shape petechia, but psoriasis has the sign that increases the weight of recently, pruritus is abnormal, myasthenia of limbs, helplessly, turn to any doctor one can find when critically ill, have the attitude of trying in arms and come the inventor to locate to seek to wish.Be diagnosed as the homeliness type psoriasis.Take the capsule of embodiment 2, after treatment February, pruritus alleviates, and white phosphorus bits reduce, and continue medication two months, and white phosphorus bits disappear, skin smooth, and recovery from illness, after treatment 1 month again, follow up a case by regular visits to so far recurrence subsequently.
Case 3: Xue, female, 70 years old.Examine in July, 2009, before readme 7 years, originally only have scalp and the proriasiform skin lesion of elbow joint position appearance, since nearest 1 year, the symptom of pain appears in elbow joint, multi-treatment poor effect once, the arthralgia phenomenon is gradually serious, joint stuffiness, myasthenia of limbs, helplessly, having the attitude of trying in arms comes the inventor to locate to seek to wish.After diagnosing, be diagnosed as " arthropathica psoriasis ", take the capsule of embodiment 3, after 30 days, the skin lesion symptom comes off gradually, and arthralgia makes moderate progress, and can do some flexors by a small margin; Continued again medication 30 days, the skin lesion position returns to the normal colour of skin substantially fully, and the arthralgia symptom disappears, activity freely, rear use was consolidated medication 30 days, the recurrence of following up a case by regular visits to that so far there are no.
Case 4: Zhang, female, 38 years old.In February, 2010, readme skin lesion onset is on the basis of acute inflammation erythema, most intensive syringe needles occur to the shallow pustule of foxtail millet grain size aseptic table, with a small amount of thin thin squama, after scurf comes off, has abscess to occur; Closely over the past half year, pustule increases rapidly, mutually is fused into large stretch of pus pasty state, with high heat, arthralgia and general malaise, be diagnosed as " pustule type psoriasis ", take the capsule of embodiment 4 after 2 months, pustule begins incrustation, most of squama comes off, continue medication 2 months, incrustation speckle and squama disappear, and skin recovers normal color, rear use was consolidated medication 30 days, the recurrence of following up a case by regular visits to that so far there are no.
The specific embodiment
Following examples are detailed description of the invention, are not any limitation of the invention.
Example 1: a kind ofly treat psoriasic Chinese medicine composition, raw material medicaments in part by weight is: Rhizoma Smilacis Glabrae 24 grams wherein, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anistree 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.
Preparation method: take each crude drug, each component is ground into 80~120 purpose powder, then mix homogeneously, make capsule according to a conventional method, and every contains effective composition 0.3 gram.
Example 2: basic identical with example 1, difference is:
Crude drug forms: 20 parts of Rhizoma Smilacis Glabraes, 15 parts of Radix Scutellariaes, 20 parts of Herba Asaris, 15 parts of Rhizoma Coptidis, 10 parts of Radix Et Rhizoma Rhei, anistree 5 parts, 20 parts of Polyporus, 15 parts, Radix Glycyrrhizae.
Example 3: basic identical with example 1, difference is:
Crude drug forms: 30 parts of Rhizoma Smilacis Glabraes, 20 parts of Radix Scutellariaes, 25 parts of Herba Asaris, 20 parts of Rhizoma Coptidis, 15 parts of Radix Et Rhizoma Rhei, anistree 10 parts, 25 parts of Polyporus, 20 parts, Radix Glycyrrhizae.
Example 4: basic identical with example 1, difference is:
Crude drug forms: 25 parts of Rhizoma Smilacis Glabraes, 18 parts of Radix Scutellariaes, 22 parts of Herba Asaris, 16 parts of Rhizoma Coptidis, 12 parts of Radix Et Rhizoma Rhei, anistree 8 parts, 22 parts of Polyporus, 18 parts, Radix Glycyrrhizae.
Example 5: basic identical with example 1, difference is:
Crude drug forms: 28 parts of Rhizoma Smilacis Glabraes, 17 parts of Radix Scutellariaes, 22 parts of Herba Asaris, 18 parts of Rhizoma Coptidis, 12 parts of Radix Et Rhizoma Rhei, anistree 6 parts, 21 parts of Polyporus, 17 parts, Radix Glycyrrhizae.

Claims (3)

1. treat psoriasic Chinese medicine composition for one kind, it is characterized in that: raw material medicaments in part by weight is: Rhizoma Smilacis Glabrae 20-30 part, Radix Scutellariae 15-20 part, Herba Asari 20-25 part, Rhizoma Coptidis 15-20 part, Radix Et Rhizoma Rhei 10-15 part, anistree 5-10 part, Polyporus 20-25 part, Radix Glycyrrhizae 15-20 part.
2. Chinese medicine composition claimed in claim 1 is characterized in that: Rhizoma Smilacis Glabrae 24 grams wherein, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anistree 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.
3. the preparation method of the described Chinese medicine composition of claim 1, it is characterized in that: take each crude drug, each component is ground into 80~120 purpose powder, then mix homogeneously, make capsule, pill or powder according to a conventional method.
CN 201110160046 2011-06-15 2011-06-15 Traditional Chinese medicinal composition for treating psoriasis and preparation method thereof Expired - Fee Related CN102824576B (en)

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CN105362440A (en) * 2015-12-10 2016-03-02 隋妍蕾 Chinese and Western medicine compound composition for treating scalp infection and preparation method of composition
CN108403920A (en) * 2018-05-31 2018-08-17 段洪明 Chinese medicine composition and the preparation method and application thereof for treating skin disease of bursting from head to foot
CN111840500A (en) * 2019-04-10 2020-10-30 王旻霞 Traditional Chinese medicine composition for treating psoriasis vulgaris

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