CN100352469C - Externally applied medicine for treating burns and scalds - Google Patents

Externally applied medicine for treating burns and scalds Download PDF

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Publication number
CN100352469C
CN100352469C CNB2004100226396A CN200410022639A CN100352469C CN 100352469 C CN100352469 C CN 100352469C CN B2004100226396 A CNB2004100226396 A CN B2004100226396A CN 200410022639 A CN200410022639 A CN 200410022639A CN 100352469 C CN100352469 C CN 100352469C
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radix
burn
medicine
herba schizonepetae
scald
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CNB2004100226396A
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CN1701800A (en
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高玉涛
高润新
高红英
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Abstract

The present invention relates to an externally applied medicine for treating burns and scalds, which is composed of the following raw medicines according to the proportion by weight: 10 to 35% of rhubarb, 10 to 35% of phellodendron bark, 10 to 35% of schizonepeta, 10 to 35% of licorice root and 10 to 35% of dahurian angelica root, wherein the rhubarb, the phellodendron bark, the schizonepeta, the licorice root and the dahurian angelica root are powder and are mixed with vegetable oil to be prepared into an oil base preparation, and an oil base accounts for at least 60% of the whole preparation. The medicine has the characteristics of simple recipe, obvious effect, low expense, no toxic or side effect, etc. The medicine is a preferred medicine for treating burns and scalds under the condition of poor medical conditions.

Description

A kind of external used medicine for the treatment of burn and scald
One, technical field
The present invention relates to Chinese medicine, particularly a kind of external used medicine for the treatment of burn and scald.
Two, background technology
Burn is damage common in our daily life, and it roughly acts on the caused damage of human body by high temperature material, electric current, chemical substance etc.
By the estimation of Depth of burn, generally adopt three degree quartering, i.e. first degree burn, superficial second degree burn, deep second degree burn and third degree burns.
I degree burn: 2-3 days inflammation eliminating masses disappear and heal.
Shallow II degree: exfoliation, blister or wound surface appear, healed no cicatrix in 5-7 days voluntarily.
The dark shallow type of II degree: the corium necrosis of shallow top layer, liquefaction is discharged, but major part survives still physiological regeneration reparation of dermal tissue, healing in 15-18 days, no cicatrix.
The dark dark type of II degree: the deep dermis partial necrosis, liquefaction is discharged, residual small part corium deep tissues, physiology and non-physiological regeneration reparation were healed in 20-26 days voluntarily, and physiological regeneration reparation person does not have cicatrix, and non-physiological regeneration reparation person leaves mild scar.
Shallow III degree: epidermis and the necrosis of corium holostrome, liquefaction is discharged, and subcutaneus adipose tissue can form granulation wound, and is good as the sweat gland epithelium regeneration reparation in the subcutaneus adipose tissue, then can form the epidermal area flap coverage and heal voluntarily.Less as sweat gland epithelium in the subcutaneus adipose tissue, can borrow surgery skin-grafting technology wound closure, more the back cicatrix.
Dark III degree: skin holostrome and subcutaneus adipose tissue total necrosis, diameter are less than the wound surface of 20cm, and the liquefiable of downright bad layer skin is discharged, and spreads the sealing healing by the edge of wound epithelium.Diameter is greater than 20, and downright bad layer skin can be used surgery skin-grafting technology excision skin-grafting healing then, more back cicatrix.
Burn not only causes the damage of local organization, and causes general reaction.The weight of general reaction has very big-difference with the size of burn surface area and the degree of depth different.
The conventional treatments that China treats burn and scald at present generally is therapy of combining Chinese and Western medicine.
Doctor trained in Western medicine mainly adopts topical agent control infection and whole body therapeutic to prevent the generation of inflammation and complication.Main nitrofural, phenoxyethanol, homosulfaminum, nystatin, the triphen first miaow of using frustrated the surface and smeared, and uses antibiotic such as penicillin, first to frustrate nitre, a full sulfanilamide, polymyxin B etc. more in a large number, and these Therapeutic Method all have very positive effect.But, adopt said method treatment burn and scald that some defectives are also arranged.Such as: A, medical procedure complexity, the condition difference of being unfavorable for the particularly medical institutions in rural area adopt; B, medical expense height; C; A large amount of antibiotic that use bring other actual bodily harm or the like to human body.
The Chinese traditional treatment burn and scald mainly adopts Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, Ilex purpurea Hassk.[I.chinensis Sims is made the soak of solution gauze or is embathed, and perhaps adopts the prescription of more complicated, as Chinese patent publication number CN1481833, and open day on 03 17th, 2004, invention and created name is a kind of medicine for external use for the treatment of burn and scald, and this application case discloses a kind of pure natural medical for the treatment of burn and scald, by Pulvis concha Anodonta seu Cristaria, Gypsum Fibrosum, Radix Sophorae Flavescentis, the Ungula Sus domestica folder, Ungula Bovis seu Bubali folder (Babalus bubalis L. hoof folder is for excellent), Os Sus domestica, dog bone, Fructus Forsythiae, Herba Violae, Radix Angelicae Sinensis, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, blood is brown, Cera Flava, white beeswax, Radix Saposhnikoviae, Pericarpium Longan, Arillus Longan kernel, dried Alumen, Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sanguisorbae, forge Calamina, Mirabilitum crystallina, Camphora, Caulis Sargentodoxae (needing system), Flos Carthami (needing system), Cortex toonae sinensis radicis, Radix Glycyrrhizae, Oleum Sesami, Oleum Camelliae, Fel Sus domestica, Margarita, Borneolum Syntheticum is formed.Its weak point complexity of filling a prescription exactly, materials are too many, are difficult for making up a prescription.
Three, technical scheme
The object of the present invention is to provide that a kind of prescription is simple, outstanding effect treatment external-use medicament for empyrosis, it is pure Chinese medicine composition.It can treat the burn and scald of various degree.Have do not make skin graft preventing from scar and prevent effect such as bacterial infection of the short treatment of clinical instant effect, cure time burn and scald, the burn and scald of various degree is all had better curative effect.
The following mode of technical solution of the present invention is carried out:
The present invention is made up of Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, Radix Angelicae Dahuricae crude drug, and its composition percentage by weight is:
Radix Et Rhizoma Rhei 10-35% Cortex Phellodendri 10-35% Herba Schizonepetae 10-35%
Radix Glycyrrhizae 10-35% Radix Angelicae Dahuricae 10-35%
Radix Et Rhizoma Rhei of the present invention, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae are Powdered, and the compositions and the vegetable oil of Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae are mixed and made into oil-based formulation, and wherein vegetable oil accounts for more than 60% of whole preparation.
Oil base of the present invention can be with cream base or water base replacement.
Herba Schizonepetae among the present invention can replace with the mustard fringe.
The mechanism of action of the present invention is: according to the research of warm cold and cool, " five tastes " the arduous salty acid of the traditional Chinese medical science " four property " and " lifting " and " monarch ".With Radix Et Rhizoma Rhei, Cortex Phellodendri is the monarch and his subjects' poison that reduce phlegm and internal heat, and Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae are stabilized the property of medicine for assistant makes, and have the merit of heat radiation analgesia concurrently.Wherein
Radix Et Rhizoma Rhei: its nature and flavor bitter cold, go into taste, large intestine, liver, pericardium channel.Compendium of Material Medica record: " main dysentery is red white, pain in the abdomen stomachache, dribbling urination, excess-heat dryness accumulated in the stomach and intestine, hectic fever delirium, all burn of jaundice ".
Cortex Phellodendri: Cortex Phellodendri is conventional Chinese medicine, and is cold in nature, bitter in the mouth.Have heat clearing and damp drying, pathogenic fire purging except that the function of steaming, skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Herba Schizonepetae: Compendium of Material Medica record: " ' wind heat of loosing, the refresh oneself, throat, the skin ulcer that disappears is swollen, controls and deceives flower in stiffness of the nape, the order and give birth to skin ulcer the moon, haematemesis, epistaxis, hematochezia, dysentery, metrorrhagia, anal fistula ".
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, wrist abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong more.
The Radix Angelicae Dahuricae: nature and flavor suffering, temperature, go into lung, spleen, stomach three warps.Expelling cold and relieving exterior syndrome is arranged, dispeiling pathogenic wind and removing dampness, pain relieving, the effect of detumescence and apocenosis.Compendium of Material Medica record: " control nasal sinusitis, epistaxis, toothache, supraorbital bone pain, large intestine constipation due to pathogenic wind ... snakebite, cutter arrow incised wound.”
Oil base among the present invention mainly refers to plant wet goods oleaginous base; Cream base mainly refers to vaseline, liquid Paraffin, substrate such as lanoline, Cera Flava, glyceryl monostearate, higher alcohol, Polyethylene Glycol and emulsifying agent; Substrate such as water base main finger aqueous solution.
Processing technology of the present invention is as follows:
Take a certain amount of Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, remove impurity,, make Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae of drying Powdered then with drying or drying with low baking temperature, be equipped with Oleum Sesami or vegetable oil again after sterilization, the mixture that obtains is finished product.
The present invention can make water preparation and unguentum as required.Water base and weight cream base accounts for more than 60% of finished product.
The present invention compares with the medicine of existing treatment burn and scald, and the utmost point has tangible good effect:
1, have no side effect: owing to adopt pure Chinese medicine batching, being aided with the traditional method process of preparing Chinese medicine, so the present invention has exempted the side effect that the patient uses Western medicine particularly to use antibiotic to bring for excess of liver-QI, kidney in a large number in a large number for pure Chinese medicinal preparation;
2, the no cicatrix in back of healing: burn and scald pachylosis occurs after curing sometimes, or shows the shallow trace that increases, or forms hypertrophic cicatrix, influences outward appearance and function.This has brought misery to extensive patients, particularly Nian Qing female patient.The present invention has been owing to adopted Oleum Sesami as substrate, can soften greatly and repairs damaged skin, alleviates the degree of burn sequelae.Simultaneously,, strengthened the pus discharge opeing of proposing of the present invention, the effect of analgesia granulation promoting owing to added the Radix Angelicae Dahuricae in the prescription.
3, treatment time is short, and expense is low: owing to adopt Chinese medicine preparation, so the required medical expense of patient is low.Simultaneously therapeutic effect of the present invention is good, and general I degree burn and scald can be fully recovered in 1 day, and II-III degree burn and scald can be fully recovered in 7-10 days, can promote greatly more than the dark III degree that slough obtains repairing, and is a kind of fabulous curative of assisting a ruler in governing a country;
4, prescription is simple, and raw material is easy to get, and is easy to operate: be specially adapted to medical condition difference or family's uses such as vast rural area.
Four, the specific embodiment
Embodiment 1: take Radix Et Rhizoma Rhei 10g, Cortex Phellodendri 20g, Herba Schizonepetae 15g, Radix Glycyrrhizae 15g, Radix Angelicae Dahuricae 25g, remove impurity, dry or dry with low baking temperature, make Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae of drying Powdered then, be equipped with Oleum Sesami or vegetable oil again after sterilization, the mixture that obtains is finished product.
Embodiment 2: take Radix Et Rhizoma Rhei 20g, Cortex Phellodendri 25g, Herba Schizonepetae 25g, Radix Glycyrrhizae 18g, Radix Angelicae Dahuricae 18g, remove impurity, dry or dry, make Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae of drying Powdered then with low baking temperature, be equipped with vaseline again after sterilization, the mixture that obtains is finished product.
Embodiment 3: take Radix Et Rhizoma Rhei 18g, Cortex Phellodendri 10g, Herba Schizonepetae 16g, Radix Glycyrrhizae 14g, Radix Angelicae Dahuricae 10g, remove impurity, dry or dry, make Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae of drying Powdered then with low baking temperature, be equipped with Mel again after sterilization, the mixture that obtains is finished product.
Five, case explanation
Case 1: high so-and-so, the woman, 9 years old, scalded breast, abdomen, arm by thermos flask accidentally, scalding area reaches 32%, wherein shallow III degree 5%, II degree 16%, I degree are 11%.
Clinical manifestation: the wound surface vesicle spreads all over, redness, 39 ℃ of body temperature, and short of breath, it is more than to cry and scream.
Therapeutic process: clean wound surface with normal saline, and immediately with medication medication of the present invention all over being coated with wound surface, the patient stops to cry and scream immediately, adopts the antiinflammatory fluid-supplement therapy immediately.Wound surface detumescence after 24 hours, body temperature descends, and the after heat detumescent disappeared on 3rd, and no liquid is oozed out, and after 7 days, the wound surface incrustation is left hospital.Check no sequel after January.
Case 2: Peng so-and-so, the man, 40 years old, for some reason by fire burn arm, hands, boiling hot burn surface area reached 17%, wherein dark III degree 7%, II degree 5%, I degree are 2%.
Clinical manifestation: patient is agonizing, and blister spreads all over, wound surface black, redness, 38.5 ℃ of body temperature, short of breath.
Therapeutic process: this patient's hand wound, clean wound surface with normal saline, and immediately with medication medication of the present invention all over being coated with wound surface, patient's pain immediately subtracts greatly, immediately the antiinflammatory fluid-supplement therapy.Wound surface detumescence after 24 hours, body temperature descends,, after 7 days, heat is swollen to disappear, and no liquid is oozed out, and the wound surface incrustation of the big portion in 10 backs was left hospital after 15 days.Check no sequel after January.

Claims (4)

1, a kind of external used medicine for the treatment of burn and scald is characterized in that being made up of Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, Radix Angelicae Dahuricae crude drug, and its composition percentage by weight is:
Radix Et Rhizoma Rhei 10-35% Cortex Phellodendri 10-35% Herba Schizonepetae 10-35%
Radix Glycyrrhizae 10-35% root of Dahurian angelica 10-35%.
2, the external used medicine of the described burn and scald of claim 1, its feature is Powdered at described Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, the Radix Glycyrrhizae spoon Radix Angelicae Dahuricae, the compositions and the vegetable oil of described Radix Et Rhizoma Rhei, Cortex Phellodendri, Herba Schizonepetae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae are mixed and made into oil-based formulation, and wherein oil base accounts for more than 60% of whole preparation.
3, the external used medicine of the described burn and scald of claim 2 is characterized in that oil base is with cream base or water base replacement.
4, the external used medicine of claim 1 or 2 or 3 described burn and scald is characterized in that the constituent Herba Schizonepetae replaces with the mustard fringe.
CNB2004100226396A 2004-05-28 2004-05-28 Externally applied medicine for treating burns and scalds Expired - Fee Related CN100352469C (en)

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CN105031287A (en) * 2015-09-18 2015-11-11 全椒先奇医药科技有限公司 Traditional Chinese medicine ointment for treating scalds
CN108159103B (en) * 2018-03-08 2020-12-01 山东第一医科大学(山东省医学科学院) A preparation containing Artemisia Selengensis for treating burn and scald, and its preparation method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1375298A (en) * 2001-01-04 2002-10-23 黄兆元 Pain-relieving notoginseng mixture

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1375298A (en) * 2001-01-04 2002-10-23 黄兆元 Pain-relieving notoginseng mixture

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