CN101244078B - Medicament for treating hemangioma and preparation thereof - Google Patents
Medicament for treating hemangioma and preparation thereof Download PDFInfo
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- CN101244078B CN101244078B CN2007100088510A CN200710008851A CN101244078B CN 101244078 B CN101244078 B CN 101244078B CN 2007100088510 A CN2007100088510 A CN 2007100088510A CN 200710008851 A CN200710008851 A CN 200710008851A CN 101244078 B CN101244078 B CN 101244078B
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- sodium carbonate
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- hemangioma
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Abstract
The invention relates to a medicament for curing hemangioma and a preparation method, belonging to the technical field of medical preparations. The invention provides a medicament for curing hemangioma and the preparation method. The medicament comprises quick lime, sodium carbonate and water. The percentage of the quick lime is 30 to 70 percent, the sodium carbonate is 30 to 70 percent, and the water is in proper proportion according to making the quick lime and the sodium carbonate paste. The preparation process comprises the steps as follows: grinding the quick lime into powder, packaging the pulverized lime into quick lime formulation and the sodium carbonate powder into sodium carbonate formulation respectively; choosing the water as liquid formulation. The medicament has the advantages of clear pharmacology, extensive sources, simple preparation technology, convenient and safe medicament, no operation and just once coating on affected part, no recurrence after cure.
Description
Technical field
The present invention relates to a kind of medicinal preparation, especially relate to a kind of quicklime and sodium carbonate of adopting and prepare medicament of treatment cutaneous hemangioma and preparation method thereof.
Background technology
Cutaneous hemangioma is a kind of common multiple disease, and particularly juvenile period, sickness rate is higher.That prior treatment method mainly contains is freezing, electrotherapy, x-ray bombardment, drug injection (for example adopting affected part direct injection sodium morrhuate etc.) and excision etc., not only cure rate is low for said method, treatment time long, medical expense is many, patient often has misery, and the normal recurrence in treatment back.
Zheng Yong provides a kind of treatment cutaneous hemangioma medicine and compound method in the application for a patent for invention of publication number for CN1120955.It comprises the medical alcohol leachate of Herba Houttuyniae, Galla Chinensis, Semen Pittospori Glabrati, Cortex Phellodendri and leaf of Pterocarya Stenoptera, alum steep, medical U.S. orchid and azone.Its preparation steps is: get Herba Houttuyniae, Folium Evodiae trichotomae is put into the first flask and added medical alcohol, sealing, soak a week after, condensate fractionation is recovered as first liquid; Smash with Cortex Phellodendri, Semen Pittospori Glabrati, alum steep for five times five and be added to, put into the second flask, add the medical alcohol sealing, soak a week after, with 2 layers of filtered through gauze, its filtrate is second; Add the blue liquid of azone and medical U.S. respectively after being poured on first liquid expansion second liquid together.
Pediatric Hospital Attached to Shanghai Medical Univ. provides angiomatous externally-applied medicinal composition of a kind of treatment and preparation method thereof in the application for a patent for invention of publication number for CN1234232, this externally-applied medicinal composition adopts tamoxifen or derivatives thereof 3-trans-Hydroxytamoxifen as active component, make semisolid and fluid composition with hydro carbons or water-soluble base, can be used for treating children's's hemangioma, tangible curative effect is arranged.
Pan Shuming provides a kind of combination type to treat angiomatous magnetic in the application for a patent for invention of publication number for CN1282614 and pastes, it is made up of the permanent magnet that contains zinc, molybdenum, copper, ferrum element and pad cloth with emission far infrared spectral line between human body and magnetic subsides of table magnetic 400-6000 Gauss, be attached to permanent magnetism above the hemangioma, main hemangioma is disappeared or dwindle, the magnetic field magnetic line direction be attached to magnetic picking for treating angioma Surface Vertical or vertical substantially, be positioned at hemangioma on extremity, brothers, the ear and can adopt two blocks of magnetic to paste relatively to paste.
Yan Qijie and Yan Feng provide a kind of injection for treating angioma and preparation technology thereof in the application for a patent for invention of publication number for CN1096683, it is made up of Folium Callicarpae Formosanae, ferric chloride, bupivacaine or lignocaine, getting light violet pearl blade of grass 500g earlier cleans and to add water 1000ml and fry in shallow oil to 600ml, remain 500ml after filtering decontamination, get 100% Folium Callicarpae Formosanae liquid 20ml then, add ferric chloride 49,1% lignocaine 80ml or 0.75% bupivacaine 80ml, fully mix thoroughly and be placed on 20 atmospheric pressure and promptly made in following 10 minutes.
Summary of the invention
The object of the present invention is to provide a kind of medicament for the treatment of cutaneous hemangioma and preparation method thereof.
Quicklime, sodium carbonate and the water of consisting of of the present invention, quicklime is 30%～70% by mass percentage, and sodium carbonate is 30%～70%, and water is an amount of, and the consumption of water is to be as the criterion quicklime and sodium carbonate furnishing pasty state.
Described water preferably adopts water for injection.
The angiomatous medicaments preparation method of treatment of the present invention may further comprise the steps:
1) the calcium lime powder breakdown mill is become the quicklime powder;
2) quicklime powder and powdered sodium carbonate are packaged into quicklime powder and sodium carbonate powder respectively;
3) select for use water as liquor.
The particle diameter of described quicklime powder is best≤0.1mm.Described water is preferably selected water for injection for use.
The using method of the angiomatous medicament of treatment of the present invention is: with liquor with quicklime powder and sodium carbonate powder furnishing scattered paste shape, apply the affected part again, apply back 30～120min this medicine is taken off the sticking shape liquid of back formation one deck black, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, black coffee can not strip off, changes dressings by the conventional anti symptom treatment of aseptic wound around the black coffee.Common 15～35 darkness coffees come off naturally, and recovery from illness leaves cicatrix.
Compare with the method for existing treatment cutaneous hemangioma, because the present invention adopts quicklime, sodium carbonate and water to be mixed with treatment cutaneous hemangioma medicament, therefore not only its pharmacology is clear, and batching is easy to get inexpensive, and preparing process is simple; And medicament is safe and convenient to use, only needs a drug, applies the affected part, needn't perform the operation, and does not recur after the treatment.Through the treatment of nearly all kinds of diseases and ailments example, recurrence and any injury situation are not arranged so far.Li Shizhen (1518-1593 A.D.) Compendium of Materia Medica (Li Shizhen (1518-1593 A.D.) work. Li Ruoxi, cart is compiled. herbal outline---the attached side of full figure, Chongqing: publishing house of University Of Chongqing, the 1st edition, 1995.28) in record, Calx abnormal smells from the patient suffering, temperature, poisonous.Cure mainly cellulitis infections scabies scabies, steam, malignant boil leprosy disease, dead flesh weighs down eyebrow, kills the hemorrhoid worm, removes the black mole polyp.Treat the marrow bone tumor.The scabies of curing the disease, meat is disliked in erosion.End incised wound blood, very good.Granulation promoting is put on flesh, hemostasis, leucoderma scrofula infections, scar defect hemorrhoid complicated by anal fistula, wart wart.Married woman's acne.Diffusing blood analgesic therapy.The coalescent nuclear of removing food stagnancy.Attached side is a blood rheumatism skin ulcer.The vast rural area that the present invention is in particular shortage of medical services and medicines provides a kind of effective therapeutic scheme, and tangible economic benefit and social benefit are arranged.
The specific embodiment
Following examples will be further described preparation method of the present invention and the result of use in clinical.
Embodiment 1
With quicklime 40g pulverize grind the quicklime powder, particle diameter is less than 0.05mm; With the sealing of bottling respectively of 40g quicklime powder and 60g powdered sodium carbonate, quicklime powder and sodium carbonate powder, select for use water for injection as liquor, the bottling sealing.
Embodiment 2
With quicklime 50g pulverize grind the quicklime powder, particle diameter is less than 0.1mm; With the sealing of bottling respectively of 50g quicklime powder and 50g powdered sodium carbonate, quicklime powder and sodium carbonate powder, select for use water for injection as liquor, the bottling sealing.
Embodiment 3
With quicklime 30g pulverize grind the quicklime powder, particle diameter is less than 0.01mm; With the sealing of bottling respectively of 30g quicklime powder and 70g powdered sodium carbonate, quicklime powder and sodium carbonate powder, select for use water for injection as liquor, the bottling sealing.
Embodiment 4
With quicklime 70g pulverize grind the quicklime powder, particle diameter is less than 0.05mm; With the sealing of bottling respectively of 70g quicklime powder and 30g powdered sodium carbonate, quicklime powder and sodium carbonate powder, select for use water for injection as liquor, the bottling sealing.
The angiomatous medicament of treatment of the present invention is through a large amount of clinical uses, below only provides the concrete clinical case of part.
Case 1. boy babies, Bears *, the Wuhan City, Hubei Province, birthplace soon, finds that child's left clavicle has 1 strip cutaneous hemangioma after the birth, is about 1cm, also there are 3 little cutaneous hemangioma on the umbilicus limit, exceeds skin.Be born back 35 days, and found that the strip cutaneous hemangioma on the left clavicle limit had the thumb size, 3 little cutaneous hemangioma on umbilicus limit also join together.The commune hospital at boy baby place is diagnosed as cavernous hemangioma, but the treatment of having no idea.Adopt cryotherapy after have to sending the attached a certain examination in hospital in Wuhan, every 4 days freezing 1 time, after freezing 4 times, angiomatous swollen bag comes off altogether, and the affected part is bigger depression.But grow swollen bag after 1 month again, arrive attached certain examination in hospital in Wuhan again, introduced by the attached a certain hospital in Wuhan and remove certain stomatological hospital tumor specific treatment, stomatological hospital adopts the Therapeutic Method of sodium morrhuate to the affected part injection.Injection in 7 days 1 time is injected 5 times altogether, and blood vessel struma bag does not only dwindle and increases faster greatlyyer on the contrary, and it is big that cavernous hemangioma has 5cm * 3cm * 2.5cm, withstands mandibular bone.The angiomatous pharmaceutical treatment of treatment of the present invention is adopted in the back, earlier quicklime powder and sodium carbonate powder are mixed, add water for injection again, furnishing scattered paste shape medicament, again the scattered paste shape medicament is applied on hemangioma, apply back 120min, form the sticking shape liquid of one deck black until this medicine being taken off the back, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, changes dressings by the conventional anti symptom treatment of aseptic wound around the black coffee, through 35 days intensive care wound healings, follow-up observation without any unusually, also finds no other injury so far.
Case 2. Zou * *, the woman, 1 year old, great order city, Hubei Province, birthplace, long 3cm * the 3cm of waist * 1cm size cavernous hemangioma, with the angiomatous pharmaceutical treatment of treatment of the present invention, earlier quicklime powder and sodium carbonate powder are mixed, add water for injection, furnishing scattered paste shape medicament, again the scattered paste shape medicament is applied on hemangioma, apply back 120min, form the sticking shape liquid of one deck black until this medicine being taken off the back, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, changes dressings recovery from illness in back 30 days around the black coffee by the conventional anti symptom treatment of aseptic wound.
Case 3. Liu * *, the woman, 1 year old, the Wuhan City, Hubei Province, birthplace, director Guan 2cm * 2cm in the right hand * 1cm size cavernous hemangioma, with the angiomatous pharmaceutical treatment of treatment of the present invention, earlier quicklime powder and sodium carbonate powder are mixed, add water for injection, furnishing scattered paste shape medicament, again the scattered paste shape medicament is applied on hemangioma, apply back 60min, form the sticking shape liquid of one deck black until this medicine being taken off the back, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, changes dressings recovery from illness in back 30 days around the black coffee by the conventional anti symptom treatment of aseptic wound.
Case is 4. sweet * *, the man, 9 months, Hubei, birthplace Jiangxia District, cutaneous hemangioma recurs after cold therapy, minister 1.5cm * 0.5cm below the left eye * 0.2cm big and small vessel tumor, with the angiomatous pharmaceutical treatment of treatment of the present invention, earlier quicklime powder and sodium carbonate powder are mixed, add water for injection, furnishing scattered paste shape medicament, again the scattered paste shape medicament is applied on hemangioma, apply back 60min, form the sticking shape liquid of one deck black until this medicine being taken off the back, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, changes dressings recovery from illness in 32 days around the black coffee by the conventional anti symptom treatment of aseptic wound.
Case 5. height * *, the man, 9 months, Jiayu County, Hubei, birthplace, cutaneous hemangioma recurs after electrotherapy, and right hand middle finger joint 2.5cm * 2.5cm * 1cm size cavernous hemangioma is with recovery from illness in 35 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 6. ten thousand * *, the woman, 45 years old, Jiayu County, Hubei, birthplace, recur after electrotherapy, the long 1.5cm * 0.5cm of following lip * 0.2cm size cavernous hemangioma is with the angiomatous pharmaceutical treatment of treatment of the present invention, earlier quicklime powder and sodium carbonate powder are mixed, add water for injection, furnishing scattered paste shape medicament applies the scattered paste shape medicament on hemangioma again, apply back 60min, form the sticking shape liquid of one deck black until this medicine being taken off the back, again wound is prevented infecting aseptic conventional wrapping, 1 day affected part becomes the thicker black coffee of one deck at interval, change dressings recovery from illness in back 31 days around the black coffee by the conventional anti symptom treatment of aseptic wound.
Case 7. rivers * *, the man, 4 years old, the birthplace xianning,hubei recurred after electrotherapy, and right crus of diaphragm foot tendon director 1.5cm * 1cm * 0.5cm size cavernous hemangioma is with recovery from illness in 33 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 8. Liu * *, the woman, 11 years old, Hubei, birthplace Jiangxia District, cutaneous hemangioma, all recurrences after the underwent operative, the long 2.5cm * 2cm in left thigh lower end * 1.5cm size cavernous hemangioma is with recovery from illness in 36 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 9. Liu * *, the man, 9 months, the birthplace xianning,hubei, long 2cm * 2cm under the bilateral breast * 0.5cm size cavernous hemangioma is with recovery from illness in 30 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 10. kings * *, the man, 6 months, the birthplace xianning,hubei, crown minister 1.5cm * 1.5cm * 0.5cm size cavernous hemangioma is with recovery from illness in 27 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 11. Yuan * *, the man, 6 months, the birthplace xianning,hubei, long 2.4cm * 1cm on the ear of left side * 0.5cm size cavernous hemangioma is with recovery from illness in 31 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.In addition at the long 1cm * 1cm in lower end, back * 0.2cm size cavernous hemangioma, with recovery from illness in 28 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 12. kings * *, the woman, 9 months, the birthplace xianning,hubei, long 2 the 1.0cm * 1cm in back * 0.2cm size cavernous hemangioma are with recovery from illness in 26 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 13. wishes * *, the woman, 10 months, Hubei, birthplace Jiangxia District, front head of district 4cm * 2cm * 1cm size cavernous hemangioma is with fully recovering in 35 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 14. Meng * *, the man, 6 months, the birthplace xianning,hubei, crown minister 1.5cm * 1.5cm * 0.2cm size cavernous hemangioma is with fully recovering in 28 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 15. Wus * *, the woman, 10 months, Hubei, birthplace Jiangxia District, the long 3cm * 2cm in back * 0.5cm size cavernous hemangioma is with recovery from illness in 30 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case is 16. old * *, the woman, 6 months, birthplace xianning,hubei city, front head of district 3cm * 1.8cm * 1cm size cavernous hemangioma is with fully recovering in 30 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.Other is long 3cm * 2cm * 0.5cm size cavernous hemangioma at the back, with recovery from illness in 28 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 17. Zheng * *, the man, 1 month, birthplace xianning,hubei city, right hand tiger director 1cm * 0.3cm * 0.1cm size cavernous hemangioma is with recovery from illness in 18 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 18. Liu * *, the man, 9 years old, Honghu City, Hubei, birthplace, the long 2.5cm * 2cm of head term * 0.5cm size cavernous hemangioma is with recovery from illness in 32 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 19. height * *, the man, 8 months, Jiayu County, Hubei, birthplace, minister 3cm * 1.5cm on the left thigh * 1cm size cavernous hemangioma is with recovery from illness in 31 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 20. Wus * *, the man, 9 months, Jiayu County, Hubei, birthplace, the long 3cm * 2cm in back * 1cm size cavernous hemangioma is with recovery from illness in 30 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 21. Bearss * *, the man, 5 months, Hubei, birthplace Jiangxia District, long 2cm * the 1cm in abdominal part umbilicus lower end * 0.5cm size cavernous hemangioma, long 1cm * the 0.3cm of right hand little finger of toe * 0.1cm size cavernous hemangioma, minister 1cm * 1cm under the hindbrain * 0.3cm size cavernous hemangioma is with recovery from illness in 28 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
Case 22. Liu * *, the man, 3 months, minister 1.5cm * 1cm below Hubei, the birthplace Jiangxia District, right eye * 0.3cm size cavernous hemangioma was with fully recovering in 26 days behind the angiomatous pharmaceutical treatment of treatment of the present invention.
The treatment record of the existing nearly all kinds of diseases and ailments example of the angiomatous medicament of treatment of the present invention, above-mentioned 22 examples only are a part wherein, do not have the recurrence of discovery or any injury situation to take place after all cases are cured so far.
Claims (2)
1. treat angiomatous medicament for one kind, it is characterized in that it consists of quicklime, sodium carbonate and water for injection, quicklime is 30%～70% by mass percentage, and sodium carbonate is 30%～70%, water for injection is an amount of, and the consumption of water for injection is to be as the criterion quicklime and sodium carbonate furnishing pasty state.
2. the angiomatous medicaments preparation method of treatment as claimed in claim 1 is characterized in that may further comprise the steps:
1) the calcium lime powder breakdown mill is become the quicklime powder, the particle diameter≤0.1mm of described quicklime powder;
2) quicklime powder and powdered sodium carbonate are packaged into quicklime powder and sodium carbonate powder respectively;
3) select for use water for injection as liquor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100088510A CN101244078B (en) | 2007-04-18 | 2007-04-18 | Medicament for treating hemangioma and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100088510A CN101244078B (en) | 2007-04-18 | 2007-04-18 | Medicament for treating hemangioma and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
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| CN101244078A CN101244078A (en) | 2008-08-20 |
| CN101244078B true CN101244078B (en) | 2010-10-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2007100088510A Expired - Fee Related CN101244078B (en) | 2007-04-18 | 2007-04-18 | Medicament for treating hemangioma and preparation thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1065434C (en) * | 1993-07-24 | 2001-05-09 | 周达春 | Wumiaoshuixiangao-multi-effect ointment |
| CN1329894A (en) * | 2000-06-21 | 2002-01-09 | 沈阳协合集团有限公司 | Medicine for treating wart with anti-inflammatino detoxication |
-
2007
- 2007-04-18 CN CN2007100088510A patent/CN101244078B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1065434C (en) * | 1993-07-24 | 2001-05-09 | 周达春 | Wumiaoshuixiangao-multi-effect ointment |
| CN1329894A (en) * | 2000-06-21 | 2002-01-09 | 沈阳协合集团有限公司 | Medicine for treating wart with anti-inflammatino detoxication |
Non-Patent Citations (6)
| Title |
|---|
| 刘金星，等.五妙水仙膏治疗面部色素痣600例.滨州医学院学报27 4.2004,27(4),第277页. |
| 刘金星等.五妙水仙膏治疗面部色素痣600例.滨州医学院学报27 4.2004,27(4),第277页. * |
| 张桂芳，等.五妙水仙膏在皮肤科的应用.中国麻风皮肤病杂志18 3.2002,18(3),第279-280页. |
| 张桂芳等.五妙水仙膏在皮肤科的应用.中国麻风皮肤病杂志18 3.2002,18(3),第279-280页. * |
| 李媛媛，等.五妙水仙膏治疗皮肤病460例疗效观察.第四军医大学学报8 6.1987,8(6),第414-416页. |
| 李媛媛等.五妙水仙膏治疗皮肤病460例疗效观察.第四军医大学学报8 6.1987,8(6),第414-416页. * |
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