CN103230491B - A kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof - Google Patents
A kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof Download PDFInfo
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Abstract
Treat an external Miao medicine for hemorrhoid, by the calcined Alumen 100 ~ 200 parts of following weight portion, arsenicum 1 ~ 3 part, Borax 6 ~ 12 parts, Calomelas 6 ~ 12 parts, Realgar 3 ~ 6 parts, 3 ~ 6 parts, sulfur, Calamina 4 ~ 10 parts composition.Put into local medicine tank by described proportioning, sealing, then on the smokeless stove fire of medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.Because hemorrhoid start the reaction in inflammatory symptoms, use calcined Alumen and Borax energy heat-clearing and toxic substances removing, detumescence.After adding Calomelas, Realgar, sulfur, arsenicum, phagedenoma removing the necrotic tissue goes dampness while antibacterial.Finally, add Calamina and can play convergence, antipruritic effect, make patient avoid pain; And hemorrhoid are Retarder theory, gradual withered.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hemorrhoid and preparation method thereof, particularly relate to and a kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof.
Background technology
Hemorrhoid are a kind of commonly encountered diseases, and frequently-occurring disease be as the saying goes: " ten people nine hemorrhoid, ten people nine do not cure ".Hemorrhoid are agglomerates that the displacement of anus pad pathologic hypertrophy and crissum veins beneath the skin clump stasis of blood stream are formed, and are anal and intestinal diseases.Its main clinical manifestation for having blood in stool, pain, edema, pruritus, local discomfort, secretions increase and the symptom such as to deviate from.Relevant research shows, the sickness rate of China's hemorrhoid is 46%, accounts for 70% in some district, and American-European, Japan's its sickness rate of investigation is about 40% ~ 60%.Having blood in stool, deviating from and the symptoms such as pain appears because of hemorrhoid in many patients, and had a strong impact on live and work, therefore the research and development of hemorrhoid treating medicine have important value.The method of current treatment hemorrhoid mainly contains pharmacotherapy, surgical ligation and injection treatment.But, the suggestion of present Most scholars be more than 90% hemorrhoid patients can non-operative treatment, only need surgical intervention less than the hemorrhoid patients of 10%.Pharmacotherapy can reducing swelling and alleviating pain, relief of symptoms, and turn avoid the pain of operation and the complication of injection treatment, is the Therapeutic Method that most people adopts.New treatment concept makes the Therapeutic Principle of hemorrhoid clear, and non-operative treatment especially Primary Care (adjustment dietary habit and bowel habit) and the importance for the treatment of by Chinese herbs are highlighted.Chinese medicine patent about hemorrhoid treating also has a lot, as Chinese patent (application number: 200910101925.4) provide a kind of Chinese medicine composition being used for the treatment of hemorrhoid combined for for oral administration and external, its oral traditional Chinese medicine composition is containing, for example the raw material of lower weight portion: Nodus Nelumbinis Rhizomatis 5 ~ 10 parts, 1 ~ 5 part, Alumen, dried Alumen 1 ~ 5 part, Fel Sus domestica 2 ~ 8 parts; Its external medicine composition is containing, for example the raw material of lower weight portion: Nodus Nelumbinis Rhizomatis 4 ~ 10 parts, 1 ~ 5 part, Alumen, dried Alumen 1 ~ 5 part, Borneolum Syntheticum 1 ~ 4 part, Fel Sus domestica 4 ~ 10 parts.Can be used for treating hemorrhoid, it has the function of hemostasis, removing heat from blood, clear blood stasis, relieving heat toxin.But current existing hemorrhoid medicine is difficult to the internal hemorrhoid problem solving, and can not allow hemorrhoid are withered to come off, avoid recurring again.
Summary of the invention
The object of this invention is to provide and a kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof.Miao Ethnomedicine of the present invention, not only has the curative effect of hemostasis, desilting blood, relieving heat toxin, and when making hemorrhoid dry up, in Retarder theory, necrobiosis Automatic-falling, removing the necrotic tissue and promoting granulation problem can be solved well, be specially adapted to the internal hemorrhoid of deviating from, and with annular, large-scale internal hemorrhoid is more applicable.Curative effect is reliable, without recurrence, has no side effect.
Further object is to provide a kind of preparation method for the treatment of for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine.
The present invention is the technical scheme solving the problems of the technologies described above employing:
Treat for oral administration of hemorrhoid and a topical compositions Miao Ethnomedicine, described Miao Ethnomedicine for oral administration is containing, for example lower weight portion: brown sheet 2 ~ 6 parts, Herba Agrimoniae 3 ~ 7 parts; Described topical compositions Miao Ethnomedicine is containing, for example the three phases medicine of lower weight portion: calcined Alumen 100 ~ 200 parts, arsenicum 1 ~ 3 part, Borax 6 ~ 12 parts, Calomelas 6 ~ 12 parts, Realgar 3 ~ 6 parts, 3 ~ 6 parts, sulfur, Calamina 4 ~ 10 parts; Second stage medicine: vegetable oil 100 ~ 200 parts, Corium elephatis 7 ~ 12 parts, Radix Angelicae Sinensis 6 ~ 13 parts, 6 ~ 12 parts, the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) 6 ~ 12 parts, Radix Arnebiae (Radix Lithospermi) 7 ~ 13 parts, Radix Et Rhizoma Rhei 3 ~ 6 parts, worm moves back 3 ~ 6 parts, white beeswax 13 ~ 24 parts, Olibanum 3 ~ 6 parts, Myrrha 3 ~ 6 parts; Phase III medicine: 10 ~ 20 parts, Calx, Os Draconis 10 ~ 20 parts, 9 ~ 16 parts, Cinnabaris, Borneolum Syntheticum 3 ~ 8 parts.
The preparation method of described Miao Ethnomedicine for oral administration: first get and pick clean brown sheet, puts heating in marmite and dissolves and be calcined to dried-up, take out, chop block, then adapted Herba Agrimoniae decoct water half an hour about for subsequent use.
The using method of Miao Ethnomedicine for oral administration: oral, each 20 ~ 30g, takes 2 day.
The preparation method of described topical compositions Miao Ethnomedicine: first stage medicine is first by calcined Alumen, arsenicum, Borax, Calomelas, Realgar, sulfur, Calamina, according to proportioning, puts into local medicine tank, sealing, on the smokeless stove fire of again medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.Second stage medicine first by Corium elephatis, Radix Angelicae Sinensis, the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, worm moves back, white beeswax, Olibanum, Myrrha, according to proportioning, is immersed in a hours in vegetable oil, then on the smokeless stove fire of inserting 100 DEG C or charcoal fire is forged, filter, cool, sealing is placed and preserved in the cool and get final product.Phase III medicine is first by Calx, and Os Draconis, Cinnabaris, Borneolum Syntheticum, according to proportioning, is ground into fine powder, then sealing placement is preserved in the cool and get final product.
The using method of topical compositions Miao Ethnomedicine: first stage therapy, patient gets lateral position, after the blood stasis deviate from, then with anaesthetic, medicated powder furnishing paste is applied in hemorrhoid with the cleaning of saline cotton balls, with absorbent cotton hemorrhoid is wrapped and protects anus, change dressings every day 2 ~ 3 times.After the drug of topical application, blood stasis is kermesinus or brown, and after 3 ~ 4 medications, blood stasis is inflammatory symptoms reaction, and hemorrhoid surface is downright bad in speckle black, and matter is soft, has a large amount of secretions.About one week hemorrhoid withered (with the cleaning of potassium permanganate warm water at every turn before changing dressings, or cleaning with saline).Second stage therapy, applies in hemorrhoid by the plaster made, and with absorbent cotton hemorrhoid is wrapped and protects anus, and after 4 ~ 6 days, blood stasis surface is gradually in grey black, and quality is hardening gradually.Secretions obviously reduces, when hemorrhoid self falling after downright bad duricrust shape decrustation.Phase III therapy, applies the affected part after hemorrhoid come off by the medicated powder made, then spreads upon around the skin around affected part with tetracycline ointment, finally with absorbent cotton the affected part after hemorrhoid come off is wrapped and protects anus.
The drug effect of Miao Ethnomedicine for oral administration: brown sheet and Herba Agrimoniae have effect for the treatment of hematochezia, uses together and can reach better humid-heat stagnation, effect of astringing to arrest bleeding.
The drug effect of topical compositions Miao Ethnomedicine: first stage: because hemorrhoid are inflammatory symptoms reaction in the first stage, use calcined Alumen and Borax energy heat-clearing and toxic substances removing, subside a swelling.After adding Calomelas, Realgar, sulfur, arsenicum, phagedenoma removing the necrotic tissue goes dampness while antibacterial.Finally, add Calamina and can play convergence, antipruritic effect, make patient avoid pain.And hemorrhoid are Retarder theory, necrobiosis.Second stage: because second stage blood stasis surface is gradually in grey black, quality is hardening gradually, uses the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, worm moves back and this kind ofly return cold medical material, can reach loose wind, clearing away heat and cooling blood, attack effect of stagnant removing toxic substances.The wound coordinating the Corium elephatis belonging to warm nature to cure mainly out ulcer not receive for a long time, makes obviously to reduce at secretions, meanwhile, when hemorrhoid self falling after downright bad duricrust shape decrustation.Finally add the Radix Angelicae Sinensis, white beeswax, Olibanum, the Myrrha that belong to warm nature to play and invigorate blood circulation, analgesic therapy, effect of removing toxic substances, make patient avoid pain.Phase III: due to phase III hemorrhoid Automatic-falling.Calx cures mainly the outer wound closed up for a long time and not, adds that Os Draconis and Cinnabaris can play tranquillization with heavy prescription, effect of promoting tissue regeneration and ulcer healing while antibacterial.Finally, add Borneolum Syntheticum and lead to all keys, loose stagnated fire, reducing swelling and alleviating pain, makes patient avoid pain.And the illing skin energy well promoting tissue regeneration and ulcer healing that hemorrhoid come off, patient can recover daily orthobiosis.
Selected Miao Ethnomedicine composition has following characteristics.
Palm fibre sheet: property is put down, bitter and puckery flavor, function astringing to arrest bleeding, and its function cures mainly: haematemesis, metrorrhagia and leukorrhagia, have blood in stool, dysentery etc.
Herba Agrimoniae: bitter, puckery is flat.GUIXIN, Liver Channel astringing to arrest bleeding, dysentery relieving.Its function cures mainly: be widely used in various hemorrhage card, such as: haematemesis, hematuria, have blood in stool, metrorrhagia, spitting of blood, epistaxis, dysentery, impairment caused by overstrain takes off power, carbuncle, traumatic injury, the cards such as wound hemorrhage.
Calcined Alumen: sour and astringent, cold.Its function cures mainly: have convergence, antiinflammatory, antisepsis.
Arsenicum: pungent, acid, heat.Return spleen, lung, stomach, large intestine channel.Its function cures mainly: eliminate the phlegm, phagedenoma removing the necrotic tissue, preventing the attack (or recurrence) of malaria.
Borax: sweet is salty, cool.Attach to the lung and stomach meridians.Its function cures mainly: external heat-clearing and toxic substances removing, detumescence, anticorrosion; Removing heat from the lung and dissipating phlegm for oral administration.
Calomelas: gas without, lightly seasoned.Its function cures mainly: antifungic action.
Realgar: pungent, temperature.Return liver, large intestine channel.Its function cures mainly: dampness, preventing the attack (or recurrence) of malaria.
Sulfur: warm in nature, sour in the mouth.Return kidney channel, large intestine channel.Its function cures mainly: for scabies, eczema, skin pruritus, chills and pain of the waist and kness, deficiency and coldness constipation.
Calamina: sweet is flat.Return stomach warp.Its function cures mainly: have convergence, antipruritic, antibacterial, slight antisepsis.
Corium elephatis: Gan Xian, temperature.Enter bladder meridian, enter spleen channel.Its function cures mainly: control traumatic hemorrhage, and all wounds.Ulcer does not close up for a long time.
Radix Angelicae Sinensis: pungent, bitter, warm in nature, return liver, the heart, spleen channel.Its function cures mainly: all cards of blood deficiency, and lump in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia.
The Radix Rehmanniae: sweet, cold.GUIXIN, liver, kidney channel.Its function cures mainly: clearing away heat and cooling blood, and yin nourishing is promoted the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.
The Pseudobulbus Bletillae (Rhizoma Bletillae): bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.Its function cures mainly: hemostasis, detumescence, granulation promoting, sore.Control epistaxis, incised wound is hemorrhage, swollen ulcer drug, canker sores.
Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.GUIXIN, Liver Channel.Its function cures mainly: removing heat from blood, invigorates blood circulation, removing toxic substances rash.
Radix Et Rhizoma Rhei: bitter, cold.Stomach warp; Large intestine channel; Liver Channel; Spleen channel.Its function cures mainly: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.
Worm moves back: sweet, cold.Return lung, Liver Channel.Its function cures mainly: loose wind heat extraction, rash, nebula removing, spasmolytic.
White beeswax: sweet is light.Return spleen, stomach, large intestine channel.Its function cures mainly: hemostasis, analgesic therapy, removing toxic substances, granulation promoting.
Olibanum: arduous, temperature.Enter the heart, liver, spleen channel.Its function cures mainly: regulating qi and activating blood, and analgesic therapy chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore.
Myrrha: bitter, pungent is flat.Enter liver, spleen, the heart, kidney channel.Its function cures mainly: analgesic therapy of invigorating blood circulation, detumescence and promoting granulation, and treatment of ulcer does not close up after bursting for a long time.
Calx: pungent, temperature, enters liver, spleen.Its function cures mainly: to the wound do not closed up for a long time, and tattered cold injury, scald etc. are effective in cure.
Os Draconis: sweet puckery are flat.Enter the heart, liver, kidney, large intestine channel.Function cures mainly: tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Cure mainly ulcer not close up for a long time.
Cinnabaris: sweet is cool.GUIXIN warp.Function cures mainly: calm, convulsion, and external has suppression and killing action to skin bacterium and parasite.
Ice powder: acrid in the mouth is bitter, is slightly cold.Enter the heart, lung meridian.Its function cures mainly: logical all keys, loose stagnated fire, reducing swelling and alleviating pain.
Described Miao Ethnomedicine component all uses the crude drug in Guizhou Plateau Miao ethnic group area, and add that traditional concocting method is made, material is easily got, and formula and preparation method simply, prepare consumption cost cheap.
The invention has the beneficial effects as follows, externally-applied medicine composite has removing heat from blood, dissipating blood stasis hemostasis, the hemorrhoid that thirst make hemorrhoid Automatic-falling, without recurrence, and the good effects had no side effect; With PA/Paste external, only make internal hemorrhoid that slow progressive mummification necrosis occurs, the scope of medicine corrosion structure is only in the local of contact, and not easily health tissues spreads towards periphery; Again because duricrust shape crust appears in the hemorrhoidal tissue of the tissue that is corroded, when decrustation, organize and repair, do not occur in treatment infecting and hemorrhage complication.The hemorrhoid that oral medicine of the present invention causes treatment humid-heat stagnation, anal fissure, fecal blood have desirable curative effect.This Miao medicine formula is prescription handed down from one's ancestors, and through the Clinical practice of more than 60 years, curative effect was reliable, without recurrence, had no side effect.
Detailed description of the invention
Embodiment 1, a kind of preparation and using method thereof for the treatment of for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine
Get brown sheet 20g, Herba Agrimoniae 35g, calcined Alumen 500g, arsenicum 5g, Borax 30g, Calomelas 30g, Realgar 15g, sulfur 15g, Calamina 20g, vegetable oil 500g, Corium elephatis 35g, Radix Angelicae Sinensis 30g, Radix Rehmanniae 30g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Radix Arnebiae (Radix Lithospermi) 35g, Radix Et Rhizoma Rhei 15g, worm moves back 15g, white beeswax 65g, Olibanum 15g, Myrrha 15g, Calx 50g, Os Draconis 50g, Cinnabaris 45g, Borneolum Syntheticum 15g.
Described Miao Ethnomedicine for oral administration, first gets and picks clean brown sheet, puts heating in marmite and dissolves and be calcined to dried-up, take out, chop block, then adapted Herba Agrimoniae decoct water half an hour about for subsequent use.
Described topical compositions Miao Ethnomedicine, the first stage first by calcined Alumen, arsenicum, Borax, Calomelas, Realgar, sulfur, Calamina is according to proportioning, put into local medicine tank, sealing, then on the smokeless stove fire of medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.Second stage first by Corium elephatis, Radix Angelicae Sinensis, the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, worm moves back, white beeswax, Olibanum, Myrrha, according to proportioning, is immersed in a hours in vegetable oil, then on the smokeless stove fire of inserting 100 DEG C or charcoal fire is forged, filter, cool, sealing is placed and preserved in the cool and get final product.Phase III, Os Draconis, Cinnabaris, Borneolum Syntheticum was ground into fine powder according to proportioning, then preserves in the cool with glass bottle sealing placement and get final product first by Calx.
The using method of Miao Ethnomedicine for oral administration: oral, each 20 ~ 30g, takes 2 day.
The using method of topical compositions Miao Ethnomedicine: first stage therapy, patient gets lateral position, after the blood stasis deviate from, then with anaesthetic, medicated powder furnishing paste is applied in hemorrhoid with the cleaning of saline cotton balls, with absorbent cotton hemorrhoid is wrapped and protects anus, change dressings every day 2 ~ 3 times.After the drug of topical application, blood stasis is kermesinus or brown, and after 3 ~ 4 medications, blood stasis is inflammatory symptoms reaction, and hemorrhoid surface is downright bad in speckle black, and matter is soft, has a large amount of secretions.Within about one week, hemorrhoid are withered.(with the cleaning of potassium permanganate warm water at every turn before changing dressings, or cleaning with saline) second stage therapy, applies in hemorrhoid by the plaster made; with absorbent cotton hemorrhoid are wrapped and protect anus; after 4 ~ 6 days, blood stasis surface is gradually in grey black, and quality is hardening gradually.Secretions obviously reduces, when hemorrhoid self falling after downright bad duricrust shape decrustation.Phase III therapy, applies the affected part after hemorrhoid come off by the medicated powder made, then spreads upon around the skin around affected part with tetracycline ointment, finally with absorbent cotton the affected part after hemorrhoid come off is wrapped and protects anus.
Embodiment 2, a kind of preparation and using method thereof for the treatment of for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine
Get brown sheet 30g, Herba Agrimoniae 35g, calcined Alumen 1000g, arsenicum 15g, Borax 60g, Calomelas 60g, Realgar 30g, sulfur 30g, Calamina 50g, vegetable oil 1000g, Corium elephatis 60g, Radix Angelicae Sinensis 65g, Radix Rehmanniae 60g, Pseudobulbus Bletillae (Rhizoma Bletillae) 60g, Radix Arnebiae (Radix Lithospermi) 65g, Radix Et Rhizoma Rhei 30g, worm moves back 30g, white beeswax 120g, Olibanum 30g, Myrrha 30g, Calx 100g, Os Draconis 100g, Cinnabaris 80g, Borneolum Syntheticum 40g.
Described Miao Ethnomedicine for oral administration, first gets and picks clean brown sheet, puts heating in marmite and dissolves and be calcined to dried-up, take out, chop block, then adapted Herba Agrimoniae decoct water half an hour about for subsequent use.
Described topical compositions Miao Ethnomedicine, the first stage first by calcined Alumen, arsenicum, Borax, Calomelas, Realgar, sulfur, Calamina is according to proportioning, put into local medicine tank, sealing, then on the smokeless stove fire of medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.Second stage first by Corium elephatis, Radix Angelicae Sinensis, the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, worm moves back, white beeswax, Olibanum, Myrrha, according to proportioning, is immersed in a hours in vegetable oil, then on the smokeless stove fire of inserting 100 DEG C or charcoal fire is forged, filter, cool, sealing is placed and preserved in the cool and get final product.Phase III, Os Draconis, Cinnabaris, Borneolum Syntheticum was ground into fine powder according to proportioning, then preserves in the cool with glass bottle sealing placement and get final product first by Calx.
The using method of Miao Ethnomedicine for oral administration: oral, each 30 ~ 35g, takes 2 day.
The using method of topical compositions Miao Ethnomedicine: first stage therapy, patient gets lateral position, after the blood stasis deviate from, then with anaesthetic, medicated powder furnishing paste is applied in hemorrhoid with the cleaning of saline cotton balls, with absorbent cotton hemorrhoid is wrapped and protects anus, change dressings every day 2 ~ 3 times.After the drug of topical application, blood stasis is kermesinus or brown, and after 3 ~ 4 medications, blood stasis is inflammatory symptoms reaction, and hemorrhoid surface is downright bad in speckle black, and matter is soft, has a large amount of secretions.Within about one week, hemorrhoid are withered.(with the cleaning of potassium permanganate warm water at every turn before changing dressings, or cleaning with saline) second stage therapy, applies in hemorrhoid by the plaster made; with absorbent cotton hemorrhoid are wrapped and protect anus; after 4 ~ 6 days, blood stasis surface is gradually in grey black, and quality is hardening gradually.Secretions obviously reduces, when hemorrhoid self falling after downright bad duricrust shape decrustation.Phase III therapy, applies the affected part after hemorrhoid come off by the medicated powder made, then spreads upon around the skin around affected part with tetracycline ointment, finally with absorbent cotton the affected part after hemorrhoid come off is wrapped and protects anus.
Embodiment 3, a kind of preparation and using method thereof for the treatment of for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine
Get brown sheet 25g, Herba Agrimoniae 35g, calcined Alumen 750g, arsenicum 8g, Borax 45g, Calomelas 45g, Realgar 23g, sulfur 23g, Calamina 35g, vegetable oil 750g, Corium elephatis 55g, Radix Angelicae Sinensis 45g, Radix Rehmanniae 45g, Pseudobulbus Bletillae (Rhizoma Bletillae) 45g, Radix Arnebiae (Radix Lithospermi) 55g, Radix Et Rhizoma Rhei 23g, worm moves back 23g, white beeswax 90g, Olibanum 23g, Myrrha 23g, Calx 75g, Os Draconis 75g, Cinnabaris 60g, Borneolum Syntheticum 30g.
Described Miao Ethnomedicine for oral administration, first gets and picks clean brown sheet, puts heating in marmite and dissolves and be calcined to dried-up, take out, chop block, then adapted Herba Agrimoniae decoct water half an hour about for subsequent use.
Described topical compositions Miao Ethnomedicine, the first stage first by calcined Alumen, arsenicum, Borax, Calomelas, Realgar, sulfur, Calamina is according to proportioning, put into local medicine tank, sealing, then on the smokeless stove fire of medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.Second stage first by Corium elephatis, Radix Angelicae Sinensis, the Radix Rehmanniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, worm moves back, white beeswax, Olibanum, Myrrha, according to proportioning, is immersed in a hours in vegetable oil, then on the smokeless stove fire of inserting 100 DEG C or charcoal fire is forged, filter, cool, sealing is placed and preserved in the cool and get final product.Phase III, Os Draconis, Cinnabaris, Borneolum Syntheticum was ground into fine powder according to proportioning, then preserves in the cool with glass bottle sealing placement and get final product first by Calx.
The using method of Miao Ethnomedicine for oral administration: oral, each 25 ~ 35g, takes 2 day.
The using method of topical compositions Miao Ethnomedicine: first stage therapy, patient gets lateral position, after the blood stasis deviate from, then with anaesthetic, medicated powder furnishing paste is applied in hemorrhoid with the cleaning of saline cotton balls, with absorbent cotton hemorrhoid is wrapped and protects anus, change dressings every day 2 ~ 3 times.After the drug of topical application, blood stasis is kermesinus or brown, and after 3 ~ 4 medications, blood stasis is inflammatory symptoms reaction, and hemorrhoid surface is downright bad in speckle black, and matter is soft, has a large amount of secretions.Within about one week, hemorrhoid are withered.(with the cleaning of potassium permanganate warm water at every turn before changing dressings, or cleaning with saline) second stage therapy, applies in hemorrhoid by the plaster made; with absorbent cotton hemorrhoid are wrapped and protect anus; after 4 ~ 6 days, blood stasis surface is gradually in grey black, and quality is hardening gradually.Secretions obviously reduces, when hemorrhoid self falling after downright bad duricrust shape decrustation.Phase III therapy, applies the affected part after hemorrhoid come off by the medicated powder made, then spreads upon around the skin around affected part with tetracycline ointment, finally with absorbent cotton the affected part after hemorrhoid come off is wrapped and protects anus.
Embodiment 4, a kind of toxicology test for the treatment of the Miao Ethnomedicine for oral administration of hemorrhoid
The Miao Ethnomedicine for oral administration of the treatment hemorrhoid of Example 1 ~ 3 does rat subacute toxicity test and white mice subacute toxicity test.
Rat subacute toxicity test is with treating the Miao Ethnomedicine for oral administration of hemorrhoid to rat gavage, every day three times, after 6 hours, and long run test 15 days, point two dosage group and matched groups.Heavy dose of group dosage is 15g/kg.To rat body weight, hemogram, hepatic and renal function and viscera organ pathology check and have no significant change.
White mice subacute toxicity test is be mixed in Mus material with the Miao Ethnomedicine for oral administration for the treatment of hemorrhoid to give.Divide three dosage groups.The every consumption per day 0.3g of heavy dose of group, totally 15 days, to white mice appetite and body weight, slightly reduce than matched group, viscera organ pathology learned inspection, Non Apparent Abnormality phenomenon.Without local irritant effect and haemolysis.
Embodiment 5, clinical example
Use Miao Ethnomedicine of the present invention treat hemorrhoid, cured hemorrhoid patients 6150 example, wherein use one the course for the treatment of healing person 5121 example, cure rate 96.5%; Use two the course for the treatment of healing person 1029 example, cure rate 98.1%.Healing is interpreted as: dissipating blood stasis hemostasis, the hemorrhoid that thirst make hemorrhoid Automatic-falling, without recurrence, have no side effect; There is slow progressive mummification necrosis in internal hemorrhoid, the scope of medicine corrosion structure is only in the local of contact, and not easily health tissues spreads towards periphery; Again because duricrust shape crust appears in the hemorrhoidal tissue of the tissue that is corroded, when decrustation, organize and repair, do not occur in treatment infecting and hemorrhage complication.
Typical clinical embodiment is as follows:
1, Liu, female, 36 years old, internal hemorrhoid 2 phase deviate to have phenomenon of bleeding, and adopted for oral administration of this formula and medicine for external use, cured, not recurring more so far 2 years in 7 days.
2, Wang, man, 38 years old, suffers from hemorrhoid hemorrhage nearly ten years, and this patient is fond of smoking excessive drinking, cures, poor effect to various places, adopt this formula for oral administration and medicine for external use, in 10 days, healing, does not recur so far more than a year.
3, Ma, man, 45 years old, suffer from more than ten years of hemorrhoid, internal hemorrhoid was serious, flow raft blood during stool, physical weakness, pale complexion, once arrived hospital and did and once perform the operation, but recur after postoperative 1 year, adopt for oral administration of this formula and medicine for external use, through the treatment of two weeks, successful, does not recur 3 years so far.
4, Lee, female, 18 years old, anal fissure, during defecation, anal orifice pain was bled, and adopts for oral administration of this formula and medicine for external use, cures, within 5 years so far, do not recur through treatment in 10 days.
Points for attention
(1) drug of topical application is wanted evenly, and note protection surrounding skin, available Cotton Gossypii dressing is filled out and is embedded in around blood stasis, in case medicamental pulverata is scattered outside blood stasis, causes surrounding skin red and swollen rotten to the corn;
(2) keep free movement of the bowels, every day defecation once, warm water demibain after an action of the bowels, and changing dressings in time;
(3) should lie up in therapeutic process, not make dressing move and come off;
(4) come off the stage, can not firmly artificially peel off, in order to avoid cause bleeding;
(5) the inside and outside hemorrhoid of first phase, crissum has actute infection, eczema, or with dysentery, belly cavity tumor, severe lung tuberculosis, hypertension, hepatopathy, nephropathy, heart disease, hemopathic patient and Confinement Time anemia of pregnant woman, the women etc. of age of sucking, all should not treat by this law.
Clinical example of the present invention adopts for oral administration and medicine for external use to combine treatment, does not affect the present invention and takes the separately protected of Miao Ethnomedicine and topical compositions Miao Ethnomedicine orally.
Claims (1)
1. treat an external Miao medicine for hemorrhoid, it is characterized in that: by the calcined Alumen 100 ~ 200 parts of following weight portion, arsenicum 1 ~ 3 part, Borax 6 ~ 12 parts, Calomelas 6 ~ 12 parts, Realgar 3 ~ 6 parts, 3 ~ 6 parts, sulfur, Calamina 4 ~ 10 parts composition; The preparation method of the external Miao medicine of described treatment hemorrhoid is: first by calcined Alumen, arsenicum, Borax, Calomelas, Realgar, sulfur, Calamina, according to proportioning, puts into local medicine tank, sealing, on the smokeless stove fire of again medicinal cupping being inserted 300 DEG C or charcoal fire is forged, take out, cool, pulverize, pack cooling with glass bottle, deepfreeze takes out and get final product for more than 3 months.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410133678.7A CN103860591B (en) | 2013-04-24 | 2013-04-24 | A kind of come off for hemorrhoid after the external Miao medicine and preparation method thereof of promoting tissue regeneration and ulcer healing |
| CN201510242523.1A CN104906292A (en) | 2013-04-24 | 2013-04-24 | Oral administration and external use combination Miao medicine for treating hemorrhoid and preparation method therefor |
| CN201310145243.XA CN103230491B (en) | 2013-04-24 | 2013-04-24 | A kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof |
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| CN201310145243.XA CN103230491B (en) | 2013-04-24 | 2013-04-24 | A kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof |
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| CN201410133678.7A Division CN103860591B (en) | 2013-04-24 | 2013-04-24 | A kind of come off for hemorrhoid after the external Miao medicine and preparation method thereof of promoting tissue regeneration and ulcer healing |
| CN201410133755.9A Division CN103860895A (en) | 2013-04-24 | 2013-04-24 | External-use Miao medicine used for hemorrhoid fall-off and preparation method thereof |
| CN201510242523.1A Division CN104906292A (en) | 2013-04-24 | 2013-04-24 | Oral administration and external use combination Miao medicine for treating hemorrhoid and preparation method therefor |
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| CN103230491A CN103230491A (en) | 2013-08-07 |
| CN103230491B true CN103230491B (en) | 2016-01-13 |
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| CN201310145243.XA Expired - Fee Related CN103230491B (en) | 2013-04-24 | 2013-04-24 | A kind ofly treat for oral administration of hemorrhoid and topical compositions Miao Ethnomedicine and preparation method thereof |
| CN201510242523.1A Pending CN104906292A (en) | 2013-04-24 | 2013-04-24 | Oral administration and external use combination Miao medicine for treating hemorrhoid and preparation method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103463137A (en) * | 2013-09-23 | 2013-12-25 | 席安胜 | Preparation method of hemorrhoids cream |
| CN103830311A (en) * | 2014-03-25 | 2014-06-04 | 张广业 | Externally applied traditional Chinese medicine having effects of detoxicating and destroying parasites, eliminating stagnation and durable and non-convergent ulcer, promoting tissue regeneration and activating blood |
| CN106902252A (en) * | 2017-05-09 | 2017-06-30 | 李胜鑫 | It is a kind of for treating bedsore, canker sore, hemorrhoid and the Chinese medicine preparation of anal fissure |
| CN107375811A (en) * | 2017-08-11 | 2017-11-24 | 程亚茹 | A kind of composition of medicine formula for treating hemorrhoid and its preparation and application |
| CN109316542A (en) * | 2018-11-14 | 2019-02-12 | 珠海莫姐姐健康管理有限公司 | One kind controlling hemorrhoid essential oil cream and preparation method thereof |
| CN109908174A (en) * | 2019-04-10 | 2019-06-21 | 上海市第四人民医院 | A kind of hemorrhoid section Shengji San |
| CN111544526A (en) * | 2020-06-19 | 2020-08-18 | 高艺桐 | A Chinese medicinal composition for treating hemorrhoid, and its preparation method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403098A (en) * | 2002-10-18 | 2003-03-19 | 武汉马应龙药业集团股份有限公司 | Ointment for treating piles and other anorectal diseases and its prepn |
| CN1879856A (en) * | 2006-05-01 | 2006-12-20 | 杨树民 | An externally applied ointment |
| CN101919876A (en) * | 2010-07-19 | 2010-12-22 | 田举 | Drug for treating haemorrhoids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153581C (en) * | 2001-02-28 | 2004-06-16 | 王志博 | Ointment for curing piles |
| CN101700318A (en) * | 2009-10-07 | 2010-05-05 | 陈辉煌 | Ointment for treating hemorrhoids and preparation method thereof |
| CN102218086A (en) * | 2010-04-13 | 2011-10-19 | 景履元 | Traditional Chinese medicine ointment for treating hemorrhoids |
-
2013
- 2013-04-24 CN CN201410133678.7A patent/CN103860591B/en not_active Expired - Fee Related
- 2013-04-24 CN CN201310145243.XA patent/CN103230491B/en not_active Expired - Fee Related
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403098A (en) * | 2002-10-18 | 2003-03-19 | 武汉马应龙药业集团股份有限公司 | Ointment for treating piles and other anorectal diseases and its prepn |
| CN1879856A (en) * | 2006-05-01 | 2006-12-20 | 杨树民 | An externally applied ointment |
| CN101919876A (en) * | 2010-07-19 | 2010-12-22 | 田举 | Drug for treating haemorrhoids |
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| Publication number | Publication date |
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| CN103860591B (en) | 2016-01-13 |
| CN104906292A (en) | 2015-09-16 |
| CN103860591A (en) | 2014-06-18 |
| CN103230491A (en) | 2013-08-07 |
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