CN113491744A - Traditional Chinese medicine external ointment paste and preparation method and application thereof - Google Patents
Traditional Chinese medicine external ointment paste and preparation method and application thereof Download PDFInfo
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- CN113491744A CN113491744A CN202110988633.8A CN202110988633A CN113491744A CN 113491744 A CN113491744 A CN 113491744A CN 202110988633 A CN202110988633 A CN 202110988633A CN 113491744 A CN113491744 A CN 113491744A
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- chinese medicine
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- powder
- erythromycin
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- 239000002674 ointment Substances 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title abstract description 6
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims abstract description 40
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- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 8
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- 239000000463 material Substances 0.000 description 2
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
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Classifications
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Abstract
The invention discloses an external traditional Chinese medicine ointment paste and a preparation method and application thereof, wherein the ointment paste is prepared from the following components in parts by mass: 7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier; the method comprises the following steps: s1, weighing the raw materials; s2, heating the river snail shells, grinding and sieving to obtain roasted river snail shell powder, grinding and sieving erythromycin to obtain erythromycin powder, crushing and mixing the other raw materials except the carrier, sieving by a 100-mesh sieve, uniformly mixing the raw materials with the roasted river snail shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into the carrier, and uniformly stirring to obtain a second mixture; s3, uniformly smearing the second mixture on the blank plaster to obtain the traditional Chinese medicine external ointment plaster. The traditional Chinese medicine external ointment paste disclosed by the invention has the effects of diminishing inflammation, easing pain, expelling toxin and the like, and has a good treatment effect on appendicitis and malignant tumors such as cancer and the like.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to an external traditional Chinese medicine ointment paste and a preparation method and application thereof.
Background
Appendicitis is an inflammatory change caused by various factors, is a common surgical disease and is most common in young years. The existing appendicitis treatment modes are mainly divided into two categories of non-operative treatment and operative treatment. Surgical treatment, although it can eradicate appendicitis, carries a certain risk and can cause patients to have inconvenience and suffering for a long time; the existing non-operative treatment mode generally takes a large amount of antibiotics to relieve or eliminate inflammation, but on one hand, the method still treats the symptoms and the root causes, and the disease is easy to relapse once the medicine is stopped; on the other hand, it will cause a large burden on the body of the patient, especially on the organs such as the kidney.
Cancer is a common malignant tumor, and in the past of medical technology's failure, cancer is essentially equivalent to the declared death. With the continuous development of medical technology, more and more medical means for effectively treating cancer are available, wherein chemotherapy and radiotherapy are the most typical. However, the large amount of chemical drugs to be taken during chemotherapy or the large dose of radiation to be born during radiotherapy can cause serious influence on the body of the patient, and the patient suffers from serious pain.
Moreover, it can be seen from the above that antibiotic therapy, surgical therapy, and chemotherapy and radiotherapy, which are commonly used for treating appendicitis, and cancer, are typical western medicine approaches. In fact, the application of the traditional Chinese medicine technology in the above fields is well documented.
In summary, there is an urgent need for a Chinese medicine with less pain and obvious effect for patients to relieve the pain of patients caused by appendicitis, cancer and other diseases and to have good therapeutic effect on these diseases.
Disclosure of Invention
Therefore, the embodiment of the invention provides a traditional Chinese medicine external ointment paste and a preparation method and application thereof, and aims to solve the problems in the prior art.
In order to achieve the above object, the embodiments of the present invention provide the following technical solutions:
in a first aspect, the embodiment of the invention provides a traditional Chinese medicine external ointment patch which is prepared from the following components in parts by mass:
7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier.
Preferably, the musk is an artificial musk.
Preferably, the carrier is petrolatum.
Preferably, the anti-inflammatory powder is sulfonamide anti-inflammatory powder.
In a second aspect, an embodiment of the present invention provides a method for preparing the above external traditional Chinese medicine ointment patch, including the following steps:
s1, weighing the following raw materials in parts by weight:
7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier;
s2, heating the escargot shells at 220 ℃ below 150 ℃ to enable the surfaces of the escargot shells to be brown, grinding the escargot shells and sieving the ground escargot shells through a 100-mesh sieve to obtain roasted escargot shell powder, grinding erythromycin and sieving the erythromycin through the 100-mesh sieve to obtain erythromycin powder, crushing the menthol oil, the paris polyphylla, the bletilla striata, the radix angelicae, the golden larch bark and the musk, mixing the crushed substances with the anti-inflammatory powder, sieving the crushed substances through the 100-mesh sieve, uniformly mixing the crushed substances with the roasted escargot shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into a carrier, and uniformly stirring the mixture to obtain a second mixture;
s3, uniformly smearing the second mixture on the blank plaster to obtain the traditional Chinese medicine external ointment plaster.
Preferably, the surface of the blank plaster is provided with a plurality of air holes.
In a third aspect, the embodiment of the invention provides the application of the traditional Chinese medicine external ointment paste in treating appendicitis, malignant tumors and cancers.
In a fourth aspect, the embodiment of the invention provides an oral anti-inflammatory tea used in combination with the traditional Chinese medicine external ointment patch, which is prepared from the following components in parts by mass:
5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum flower and 1.4-1.6 parts of licorice.
In a fifth aspect, the embodiment of the invention provides a use method of the oral anti-inflammatory tea, which comprises the following steps:
step A, weighing the following raw materials in parts by weight:
5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum and 1.4-1.6 parts of liquorice;
step B, soaking the raw materials in the step A for 3-5min by using 500-1000 parts of water with the temperature of more than 96 ℃ to obtain tea soup, and drinking the tea soup;
and C, repeating the step B1 times every 4-6h, and repeating the steps 3-7 times in total.
Compared with the prior art, the invention has at least the following beneficial effects:
(1) the traditional Chinese medicine external ointment paste provided by the embodiment of the invention has very good treatment effects on appendicitis, tumor and cancer, swelling and pain in brain, lumbar tuberculosis, gastric ulcer, bone necrosis, various tumor abscess bags and the like, can quickly stop pain and ulcer, and has a mild medicinal effect and an obvious effect.
(2) The traditional Chinese medicine ointment patch for external use provided by the embodiment of the invention has the advantages of rigorous compatibility of the prescription, mutual promotion and synergistic effect among all the medicinal materials, obvious anti-inflammatory and analgesic effects, no toxic or side effect on a human body, no need of oral administration and almost no harm to the human body.
(3) The traditional Chinese medicine external ointment paste provided by the embodiment of the invention has the advantages of small dosage, small medicine types, easy carrying of various medicinal materials, simple and quick manufacturing method, small limitation by appliances, places and environments, capability of quickly emergent sudden onset self-rescue or rescue of patients with sudden onset of illness, suitability for various occasions such as hospitals, families, disaster relief sites, field first-aid and the like, and high popularization value.
(4) The traditional Chinese medicine external ointment patch provided by the embodiment of the invention can be used together with the oral anti-inflammatory tea provided by the embodiment of the invention, can be used internally and externally, can supplement each other, and has very obvious promotion effect on the drug effects of the oral anti-inflammatory tea and the oral anti-inflammatory tea.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail with reference to specific embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In the description of the present invention, "a plurality" means two or more unless otherwise specified. The terms "first," "second," "third," "fourth," and the like (if any) in the description and in the claims of the present invention are intended to distinguish between the referenced items. For a scheme with a time sequence flow, the term expression does not need to be understood as describing a specific sequence or a sequence order, and for a scheme of a device structure, the term expression does not have distinction of importance degree, position relation and the like.
Furthermore, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements specifically listed, but may include other steps or elements not expressly listed that are inherent to such process, method, article, or apparatus or that are added to such process, method, article, or apparatus based on the optimization concepts of the present invention.
Examples 1 to 3 respectively provide a traditional Chinese medicine ointment patch for external use, which comprises the following components in parts by mass as shown in table 1 below:
table 1-examples 1-3 provide the components of the topical Chinese medicinal plaster in parts by mass
The preparation method of the traditional Chinese medicine external ointment patch provided in embodiment 1 comprises the following steps:
s1, weighing the following raw materials in parts by weight:
7.5 parts of menthol oil, 6.5 parts of paris polyphylla, 4.5 parts of bletilla striata, 4.5 parts of angelica dahurica, 4.5 parts of golden larch bark, 4.5 parts of musk, 4.5 parts of escargots shell, 4.5 parts of erythromycin, 4.5 parts of sulfanilamide anti-inflammatory powder and 45 parts of carrier;
s2, heating the river snail shells at 220 ℃ until the surfaces of the river snail shells turn brown, grinding the river snail shells and sieving the ground river snail shells with a 100-mesh sieve to obtain fried river snail shell powder, grinding the erythromycin in S1 and sieving the ground river snail shell powder with the 100-mesh sieve to obtain erythromycin powder, crushing the menthol oil, the rhizoma paridis, the bletilla striata, the radix angelicae, the golden larch bark and the musk, mixing the smashed mint oil, the smashed rhizoma paridis, the smashed rhizoma bletillae, the smashed radix angelicae, the golden larch bark and the musk with sulfanilamide type anti-inflammatory powder, sieving the smashed mint oil with the 100-mesh sieve, uniformly mixing the smashed mint oil, the rhizoma paridis, the dahurian angelica sinensis, the golden larch bark and the musk with roasted river snail shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into a carrier, and uniformly stirring the first mixture to obtain a second mixture;
s3, uniformly smearing the second mixture on a blank plaster with a plurality of holes on the surface to obtain the traditional Chinese medicine external ointment plaster.
Examples 2 to 3 provide a method for preparing a topical plaster of chinese medicine in the same manner as in example 1.
In the treatment of appendicitis, the application method of the traditional Chinese medicine external ointment patch provided in example 1 is as follows:
before use, the epidermis of the pain part of the patient is cleaned, cleaned and wiped dry, and 100g of the second mixture prepared in example 1 is prepared into a traditional Chinese medicine ointment patch for external use, and the traditional Chinese medicine ointment patch is pasted on the epidermis. Changing the medicine 1-2 times daily, and 5-7 days as a course of treatment, and determining the number of the course of treatment according to the situation.
In the treatment of swelling and pain in the brain, tuberculosis of lumbar vertebrae, gastric ulcer, necrosis of bone, malignant tumor, gastric cancer, lung cancer, liver cancer and other cancers, abscess, etc., the application method of the traditional Chinese medicine external ointment patch provided in example 1 is as follows:
taking a proper amount of the second mixture prepared in the embodiment 1 according to the size of the affected part to prepare a traditional Chinese medicine external ointment paste, wherein the ointment paste can completely cover the affected part; the topical ointment of example 1 was applied to the affected part after the patient had cleaned and dried, and the dressing was changed 1 time a day. 5-7 days as a course of treatment, and the number of the course of treatment is determined according to the situation; the sepsis can be pulled out after the ointment paste is used for some diseases, and the wound can be automatically healed only by cleaning the wound when the sepsis is drained and stopping taking the ointment for 2-5 days as the case may be.
Examples 2 to 3 provide a method of using the external traditional Chinese medicine ointment patch in the same manner as in example 1.
Examples 1 to 3 also provide oral anti-inflammatory tea used in combination with the traditional Chinese medicine ointment patch, wherein the following components are shown in table 2:
TABLE 2-quality parts of the components of oral anti-inflammatory tea provided in examples 1-3
| Examples | Radix tetrastigme | Herba Lysimachiae Christinae | Chrysanthemum morifolium Ramat | Licorice root, radix Glycyrrhizae |
| Example 1 | 5 | 1.8 | 1.8 | 1.4 |
| Example 2 | 7.5 | 2.0 | 2.0 | 1.5 |
| Example 3 | 10 | 2.2 | 2.2 | 1.6 |
The use method of the oral anti-inflammatory tea matched with the traditional Chinese medicine external ointment patch provided by the embodiment 1 comprises the following steps:
step A, weighing the following raw materials in parts by weight:
5 parts of radix tetrastigme, 1.8 parts of desmodium, 1.8 parts of wild chrysanthemum and 1.4 parts of liquorice;
step B, soaking the raw materials in the step A for 5min by 500 parts of water with the temperature of 98 ℃ to obtain tea soup, and drinking the tea soup;
and C, repeating the step B1 times every 4h for 7 times.
Examples 2-3 provide oral anti-inflammatory teas using the same method as example 1, except that:
in example 2, step B was repeated every 5h, 5 times;
in example 3, step B was repeated every 5h, 3 times.
Several real cases will now be provided to illustrate the advantageous effects of the embodiments of the present invention.
Patients 1, male, 45 years old and appendicitis are cured after 2 treatment courses by using the traditional Chinese medicine external ointment paste provided by the embodiment of the invention, and no operation or oral antibiotic treatment is performed in the period.
Patients 2, 7 years old and 7 years old have acute appendicitis attack in morning and have hard pain, the traditional Chinese medicine external ointment paste provided by the embodiment of the invention is used, the anti-inflammatory tea provided by the embodiment of the invention is taken at the same time, the pain feeling is obviously relieved in afternoon in the same day, the ointment paste is continuously used for a half treatment course, the anti-inflammatory tea is taken in the same period, and then the ointment paste is sent to a hospital for disease-free examination.
Patients 3, male, 40 years old and lung cancer, who want to give up at a time because they cannot bear the pain and economic pressure caused by frequent chemotherapy and radiotherapy, use the traditional Chinese medicine external ointment patch provided by the embodiment of the invention for 10 courses of treatment later, and the combined dose is lower than that of the previous chemotherapy and radiotherapy, so that the existing condition is gradually stable and has obvious signs of improvement.
The above specific embodiments may be combined with each other, and details of the same or similar concepts or processes may not be repeated in some embodiments.
All the technical features of the above embodiments can be combined arbitrarily, and for simplicity of description, all possible combinations of the technical features of the above embodiments are not described; these examples, which are not explicitly described, should be considered to be within the scope of the present description.
The present invention has been described in considerable detail by the general description and the specific examples given above. It should be noted that it is obvious that several variations and modifications can be made to these specific embodiments without departing from the inventive concept, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (9)
1. The traditional Chinese medicine external ointment patch is characterized by being prepared from the following components in parts by mass:
7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier.
2. The traditional Chinese medicine ointment patch for external use according to claim 1, wherein the musk is artificial musk.
3. The traditional Chinese medicine ointment patch for external use according to claim 1, wherein the anti-inflammatory powder is sulfonamide anti-inflammatory powder.
4. The topical ointment patch of traditional Chinese medicine according to claim 1, wherein the carrier is petrolatum.
5. A method for preparing the traditional Chinese medicine ointment patch for external use according to claim 1, which is characterized by comprising the following steps:
s1, weighing the following raw materials in parts by weight:
7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier;
s2, heating the escargot shells at the temperature of 150-220 ℃ until the surfaces of the escargot shells turn brown, grinding the escargot shells and sieving the ground escargot shells through a 100-mesh sieve to obtain roasted escargot shell powder, grinding the erythromycin and sieving the erythromycin through the 100-mesh sieve to obtain erythromycin powder, crushing the mint naphtha, the paris polyphylla, the bletilla striata, the angelica dahurica, the golden larch bark and the musk, mixing the crushed mint naphtha, the crushed substances with the inflammation diminishing powder, sieving the smashed mint naphtha, the smashed escargot shell powder and the erythromycin powder through the 100-mesh sieve to obtain a first mixture, adding the first mixture into the carrier, and uniformly stirring the first mixture to obtain a second mixture;
s3, uniformly smearing the second mixture on a blank plaster to obtain the traditional Chinese medicine external ointment plaster.
6. The method for preparing a traditional Chinese medicine ointment patch for external use according to claim 5, wherein a plurality of air holes are formed in the surface of the blank ointment patch.
7. An application of the topical ointment of claim 1 in treating appendicitis and malignant tumor.
8. An oral anti-inflammatory tea used in combination with the traditional Chinese medicine external ointment patch of claim 1 is characterized by being prepared from the following components in parts by mass:
5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum flower and 1.4-1.6 parts of licorice.
9. The use method of the oral anti-inflammatory tea according to claim 8, comprising the steps of:
step A, weighing the following raw materials in parts by weight:
5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum and 1.4-1.6 parts of liquorice;
step B, soaking the raw materials in the step A for 3-5min by using 1000 parts of water with the temperature of more than 96 ℃ to obtain tea soup, and drinking the tea soup;
and C, repeating the step B1 times every 4-6h, and repeating the steps 3-7 times in total.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1723928A (en) * | 2005-07-07 | 2006-01-25 | 云南省药物研究所 | External use medicinal composition for treating swelling paint |
| CN107823231A (en) * | 2017-11-29 | 2018-03-23 | 付保林 | The Chinese medicine composition and combination ointment of a kind for the treatment of cancer cervical spondylopathy stomach trouble appendicitis |
| CN110151893A (en) * | 2019-05-30 | 2019-08-23 | 夏清山 | A kind of analgesic ointment and preparation method thereof |
-
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1723928A (en) * | 2005-07-07 | 2006-01-25 | 云南省药物研究所 | External use medicinal composition for treating swelling paint |
| CN107823231A (en) * | 2017-11-29 | 2018-03-23 | 付保林 | The Chinese medicine composition and combination ointment of a kind for the treatment of cancer cervical spondylopathy stomach trouble appendicitis |
| CN110151893A (en) * | 2019-05-30 | 2019-08-23 | 夏清山 | A kind of analgesic ointment and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李正飞: "治胃痛秘方", 《农家科技》 * |
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Application publication date: 20211012 |