CN1306942C - Chinese medicine composition for treating recurrent ulcer of mouth - Google Patents
Chinese medicine composition for treating recurrent ulcer of mouth Download PDFInfo
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- CN1306942C CN1306942C CNB2005100460186A CN200510046018A CN1306942C CN 1306942 C CN1306942 C CN 1306942C CN B2005100460186 A CNB2005100460186 A CN B2005100460186A CN 200510046018 A CN200510046018 A CN 200510046018A CN 1306942 C CN1306942 C CN 1306942C
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Abstract
The present invention relates to a traditional Chinese medicine composition for treating recurrent oral ulcer, which belongs to the field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is composed of 15 to 20 shares of puff-ball, 6 to 9 shares of alum, 1 to 4 shares of borneol, 0 to 6 shares of licorice root and 0 to 9 shares of natural indigo. All raw medicinal materials are pulverized into fine powder, and external application medicine powder is prepared. The medicine of the present invention has the functions of clearing away heat and toxic material, relieving inflammation, relieving pain, eliminating dampness and promoting wound healing. The medicine can be used for treating tonsillitis, thrush, throat swelling pain, gingival swelling pain and oral mucosa swelling pain, particularly recurrent oral ulcer. The present invention has the advantages of rapid effect taking and high curative rate.
Description
Technical field:
The present invention relates to the Chinese medicine composition field, it is a kind of Chinese medicine composition for the treatment of recurrent oral ulceration.
Background technology:
Diseases such as oral mucosa, throat, gingival swelling and pain and comparatively serious recurrent oral ulceration, tonsillitis, thrush are comparatively common clinically, and outbreak influences feed and sleep because of violent spontaneous pain often.Western medical treatment with the part with iodine glycerol and vitamin B
1, B
2Oral with C, serious bigot's short-term hormone medicine for oral administration.At present the Chinese medicine of this disease of treatment comprises two kinds of medicine for external use and oral medicine, external preparation such as medicine for external use such as traditional XILEI SAN, BINGPENG SAN, and the medicine for external use of disclosed treatment aphthous ulcer in the patent documentation, the " Zhenhuang " powder in oral cavity collutory of in CN95105646, describing as Meng Junhong and the Wen Zhiting affected part, sprayed oral cavity described in CN95107977 or the like, these medicines carry out part alleviation or treatment to oral ulcer, can't solve the problem that the intractable oral cavity ulcer disease is shown effect repeatedly.Oral medicine comprises traditional cow-bezoar anti-toxic bolus, cow-bezoar bolus for clearing away heat of the upper part of the body etc.; but there is not special specific aim; Chen Jizhong discloses a kind of treatment oral ulcer oral medicinal herb preparation in the patent documentation in CN96102336; can shorten the course of disease, control oral ulcer recurrence, but said medicine or because of treatment time longer; or because of price more expensive; so the development good effect, price is low, and preparation easy to use remains the problem that we need solve.
For this reason, the inventor is for many years through research repeatedly, and the checking repeatedly by clinical trial, has found the Chinese medicine external used medicine that the treatment of better curative effect oral ulcer is arranged finally, thereby has finished the present invention.
Summary of the invention:
The purpose of this invention is to provide a kind of Chinese medicinal composition preparation of more effectively treating recurrent oral ulceration.
Treat the Chinese medicine composition of recurrent oral ulceration according to the present invention, it is to be made by following bulk drugs: Lasiosphaera Seu Calvatia 15-20 part, Alumen 6-9 part, Borneolum Syntheticum 1-4 part, Radix Glycyrrhizae 0-6 part and Indigo Naturalis 0-9 part.
According to the Chinese medicine composition of treatment recurrent oral ulceration of the present invention, it is to be made by following bulk drugs: 18 parts of Lasiosphaera Seu Calvatia, 8 parts in Alumen, 3 parts of Borneolum Syntheticums.
It is primary raw material that Chinese medicine composition of the present invention is selected Lasiosphaera Seu Calvatia, Alumen and Borneolum Syntheticum, with these drug regimens, makes each efficacy of drugs produce synergism, thereby can more effective treatment oral ulcer recur, wherein select Lasiosphaera Seu Calvatia for use, acrid in the mouth, property are put down, have detoxifcation, hemostasis, removing heat from the lung and relieving sorethroat, the relieving the exterior syndrome fire action; And with the pain relieving of Alumen dampness, heat clearing and inflammation relieving; Be aided with Borneolum Syntheticum, with the effect of its clearing up internal heat by using drugs of bitter in taste and cold in nature, the diffusing stagnated fire of performance, the effect of reducing swelling and alleviating pain.Three kinds of medicines are brought into play the function of heat-clearing and toxic substances removing, anti-inflammatory analgetic, eliminating dampness and astringing sores jointly.
According to the Chinese medicine composition of treatment recurrent oral ulceration of the present invention, make: Lasiosphaera Seu Calvatia 15-20 part, Alumen 6-9 part, Borneolum Syntheticum 1-4 part, Radix Glycyrrhizae 3-6 part and Indigo Naturalis 6-9 part by following bulk drugs.
According to the Chinese medicine composition of treatment recurrent oral ulceration of the present invention, it is to be made by following bulk drugs: 8 parts of 18 parts of Lasiosphaera Seu Calvatia, 8 parts in Alumen, 3 parts of Borneolum Syntheticums, 5 parts in Radix Glycyrrhizae and Indigo Naturaliss.
Owing in crude drug, added Radix Glycyrrhizae and Indigo Naturalis, for treatment aphtha, gum erosion, the oral ulcer disease curative effect of outbreak is better repeatedly, better brings into play the effect of heat-clearing and toxic substances removing.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional topical agent, for example can be with these crude drug pulverizes, and mix homogeneously is made powder, unguentum, oil preparation, tincture, spray or the like.These crude drug can be made oral preparations, as electuary, powder, tablet, pill etc.But for each raw material that makes this medicine is better brought into play drug effect, reduce toxicity, preferably crude drug is made powder or spray external, but these can not be used to limit protection scope of the present invention.
The preparation method of Chinese medicine composition of the present invention is as follows:
A) gather wild ripe Lasiosphaera Seu Calvatia, take by weighing its inner lark powder after a few days to be dried, be ground into fine powder, cross 100 mesh sieves, make the Lasiosphaera Seu Calvatia powder,
B) get it filled and forge the back, pulverize, be ground into fine powder, cross 100 mesh sieves, make alum powder with Alumen,
C) get Borneolum Syntheticum and be ground into fine powder, cross 100 mesh sieves, make Borneolum Syntheticum powder,
D) extracting liquorice, drying is ground into fine powder, crosses 100 mesh sieves, makes Radix Glycyrrhizae powder,
E) take by weighing Indigo Naturalis powder, Lasiosphaera Seu Calvatia powder, alum powder, Borneolum Syntheticum powder and Radix Glycyrrhizae powder mixing, just made Chinese medicine composition of the present invention.
Chinese medicine composition of the present invention can add various conventional adjuvant required when preparing different dosage form, as soft dose of cream, glycerol, liquid paraffin etc., make any exterior-applied formulation commonly used with conventional method of Chinese medicinal, also can add disintegrating agent, lubricant, binding agent etc. and be prepared into any peroral dosage form commonly used, as tablet, powder, pill, suspensoid etc. with conventional method of Chinese medicinal.
Chinese medicine composition of the present invention has heat-clearing and toxic substances removing, anti-inflammatory analgetic, the function of eliminating dampness and astringing sores.Can be used for treating tonsillitis, thrush, throat, gingiva, oral mucosa swelling and recurrent oral ulceration, instant effect, cure rate height.
The specific embodiment
Below by embodiment Chinese medicine composition of the present invention is described further.
Embodiment 1
According to following proportioning weighting raw materials: Lasiosphaera Seu Calvatia 18 grams, Alumen 8 grams, Borneolum Syntheticum 3 grams.
Preparation method is as follows:
A) gather wild ripe Lasiosphaera Seu Calvatia, take by weighing its inner lark powder after a few days to be dried, be ground into fine powder, cross 100 mesh sieves, make the Lasiosphaera Seu Calvatia powder,
B) get it filled and forge the back, pulverize, be ground into fine powder, cross 100 mesh sieves, make alum powder with Alumen,
C) get Borneolum Syntheticum and be ground into fine powder, cross 100 mesh sieves, make Borneolum Syntheticum powder,
D) take by weighing Lasiosphaera Seu Calvatia powder 18 grams, alum powder 8 grams, Borneolum Syntheticum powder 3 gram mixings, make powder.
Through the Chinese medicine composition of clinic trial embodiment 1, coating outward or spraying treatment patient 200 examples for throat, gingiva, oral mucosa swelling, small size ulcer, were treated 3-15 days, and effective percentage reaches 98%, can cure in general 3-7 days.
Embodiment 2
According to following proportioning weighting raw materials: Lasiosphaera Seu Calvatia 18 grams, Alumen 8 grams, Borneolum Syntheticum 3 grams, Radix Glycyrrhizae 5 grams and Indigo Naturalis 8 grams.
Its preparation method is as follows:
A) gather wild ripe Lasiosphaera Seu Calvatia, take by weighing its inner lark powder after a few days to be dried, be ground into fine powder, cross 100 mesh sieves, make the Lasiosphaera Seu Calvatia powder,
B) get it filled and forge the back, pulverize, be ground into fine powder, cross 100 mesh sieves, make alum powder with Alumen,
C) get Borneolum Syntheticum and be ground into fine powder, cross 100 mesh sieves, make Borneolum Syntheticum powder,
D) extracting liquorice, drying is ground into fine powder, crosses 100 mesh sieves, makes Radix Glycyrrhizae powder,
E) take by weighing Indigo Naturalis powder 8 grams, Lasiosphaera Seu Calvatia powder 18 grams, alum powder 8 grams, Borneolum Syntheticum powder 3 grams and Radix Glycyrrhizae powder 5 gram mixings, make powder.
Through coating of Chinese medicine composition beyond the region of objective existence or spraying treatment patient 50 examples of clinic trial embodiment 2, treatment recurrent oral ulceration total effective rate 96% now is summarized as follows:
1, diagnostic criteria: oral ulcer takes place repeatedly, and intermittently indefinite, severe patient rises one after another, and mostly occurs at tongue, cheek, lip, soft palate etc.Ulcer is rounded or oval, under the central fovea, on it coated with faint yellow pseudomembrane, light-duty ulcer, diameter 2-3mm, number is less, generally can heal in 1-2 week, cicatrix is not stayed in healing, than principal characteristic ulcer, and nearly tens of numbers, diameter is at 3-5nm, even 10mm, the course of disease can reach several weeks to the several months, leaves white cicatrix after healing.
2, Therapeutic Method: apply the affected part in right amount, every day, for several times first quarter moon was a course of treatment, 2 courses of treatment of logotype.
3, efficacy assessment standard:
Cure: various aphtha heals after treating, and observes 2 months, does not have recurrence.
Produce effects: various aphtha is after treatment, and the intermission prolongs, and observes 2 months, does not have recurrence.
Take a turn for the better: healing time is accelerated, and the intermission prolongs, and pain degree alleviates, and ulcer decreased number and diameter diminish and wait 5 indexs, have wherein 3 above persons after treating.
Invalid: as not reach improvement standard person.
4, therapeutic outcome:
Observation of curative effect table after treating
| Treatment time (my god) | Cure | Produce effects | Take a turn for the better | Invalid | Effective percentage % | ||||
| The example number | Cure rate % | The example number | Obvious effective rate % | The example number | Improvement rate % | The example number | Inefficiency % | ||
| 3 | 2 | 4 | 18 | 36 | 18 | 36 | 12 | 24 | 76 |
| 7 | 11 | 22 | 16 | 32 | 15 | 30 | 8 | 16 | 84 |
| 15 | 17 | 34 | 15 | 30 | 13 | 26 | 5 | 10 | 90 |
| January | 21 | 42 | 18 | 36 | 9 | 18 | 2 | 4 | 96 |
Claims (4)
1, a kind of Chinese medicine composition for the treatment of recurrent oral ulceration is characterized in that it is to be made by following bulk drugs: Lasiosphaera Seu Calvatia 15-20 part, Alumen 6-9 part, Borneolum Syntheticum 1-4 part, Radix Glycyrrhizae 0-6 part and Indigo Naturalis 0-9 part.
2, the Chinese medicine composition of treatment recurrent oral ulceration according to claim 1 is characterized in that it is to be made by following bulk drugs: 18 parts of Lasiosphaera Seu Calvatia, 8 parts in Alumen, 3 parts of Borneolum Syntheticums.
3, the Chinese medicine composition of treatment recurrent oral ulceration according to claim 1 is characterized in that it is to be made by following bulk drugs: Lasiosphaera Seu Calvatia 15-20 part, Alumen 6-9 part, Borneolum Syntheticum 1-4 part, Radix Glycyrrhizae 3-6 part and Indigo Naturalis 6-9 part.
4, the Chinese medicine composition of treatment recurrent oral ulceration according to claim 3 is characterized in that it is to be made by following bulk drugs: 8 parts of 18 parts of Lasiosphaera Seu Calvatia, 8 parts in Alumen, 3 parts of Borneolum Syntheticums, 5 parts in Radix Glycyrrhizae and Indigo Naturaliss.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100460186A CN1306942C (en) | 2005-03-14 | 2005-03-14 | Chinese medicine composition for treating recurrent ulcer of mouth |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100460186A CN1306942C (en) | 2005-03-14 | 2005-03-14 | Chinese medicine composition for treating recurrent ulcer of mouth |
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| CN1682909A CN1682909A (en) | 2005-10-19 |
| CN1306942C true CN1306942C (en) | 2007-03-28 |
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| CNB2005100460186A Expired - Fee Related CN1306942C (en) | 2005-03-14 | 2005-03-14 | Chinese medicine composition for treating recurrent ulcer of mouth |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103751560B (en) * | 2014-02-18 | 2015-10-28 | 赵秀华 | A kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration |
| CN105126154B (en) * | 2015-08-25 | 2018-06-01 | 东莞市达庆医疗器械有限公司 | A kind of medical bio nasal cavity rapid hemostasis powder and preparation method thereof |
| CN106729003A (en) * | 2016-11-09 | 2017-05-31 | 佘鹏 | A kind of Chinese medicine for treating acute tonsillitis disease and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1371700A (en) * | 2001-02-28 | 2002-10-02 | 郑培乐 | Medicine for treating stomatocase |
| CN1406598A (en) * | 2001-08-17 | 2003-04-02 | 王树茂 | Oral cavity ulcer powder and preparation thereof |
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2005
- 2005-03-14 CN CNB2005100460186A patent/CN1306942C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1371700A (en) * | 2001-02-28 | 2002-10-02 | 郑培乐 | Medicine for treating stomatocase |
| CN1406598A (en) * | 2001-08-17 | 2003-04-02 | 王树茂 | Oral cavity ulcer powder and preparation thereof |
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| CN1682909A (en) | 2005-10-19 |
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