CN105233065A - Traditional Chinese medicine composition for treating gingivitis - Google Patents

Abstract

The invention provides a traditional Chinese medicine composition for treating gingivitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials of radix clematidis, drynaria rhizome, rheum officinale, cassia twig, frankincense, herba cepbalanoplosis segeti, lophatherum gracile, and corydalis tuber. The total raw materials in the formula are combined to interact synergistically, so that the effects of removing the wind and eliminating dampness, purging the heat and detoxifying, expelling stasis and relieving pains, promoting blood circulation to eliminate swell, and constringing and relieving bleeding are achieved, and therefore, the effect of effectively treating gingivitis is achieved.

Description

A kind of Chinese medicine composition for the treatment of gingivitis

Technical field:

The invention belongs to technical field of Chinese medicine, relate to a kind of medicine for the treatment of oral disease, be specifically related to a kind of Chinese medicine composition for the treatment of gingivitis and preparation method thereof.

Background technology:

Gingivitis (Gingivitis) is one of the commonly encountered diseases and frequently-occurring disease of clinical oral, medically will around and cover periodontal soft tissue and be called gingiva, the active chronic inflammation betiding gingiva tissue is called gingivitis.Show as gingival hemorrhage, red and swollen, distending pain, continues development and invades sclerous tissues, produce periodontitis, comprises the performance at gingiva of the inflammation of gingiva tissue and general disease.According to the gingivitis classification method of international symposium in 1999, the gingival (as the gingival that virus, fungus etc. cause, general disease is in the performance and heritability pathological changes etc. of gingiva) that gingival divide for the gingival (as marginal gingivitis, pubertal gingivitis, pregnancy gingivitis, drug induced gingival hyperplasia etc.) that caused by bacterial plaque and non-bacterial plaque to cause.The treatment of gingivitis comprises removes bacterial plaque, tartar, eliminates and causes bacterial plaque to be detained and the aspect such as the factor of local excitation gingiva and topical medications.

The use of antibiotic collutory has achieved significant curative effect in clinical treatment gingivitis, wherein containing 0.12% hibitane preparation be use the most extensively, the most effective.It is cationic surfactant, has the bactericidal properties of wide spectrum.But for a long time with tooth, back can be made painted, the sense of taste may be caused to damage.The development of gingivitis or periodontal disease although the application of antibiotics can stop or slow down.But the problem of its side effect and drug resistance, makes the application of antibiotics to this disease be restricted, can only as one of auxiliary treating method.

The traditional Chinese medical science thinks that gingivitis belongs to gingival abscess, toothache, bleeding from the gum category, and the traditional Chinese medical science thinks that gingivitis, gingival swelling and pain mostly are that the evil poison of wind and cold is invaded, cold-evil solidifyingly closes, venation impatency causes, its Therapeutic Method when based on expelling wind and removing dampness, expel the heat-evil removing toxic substances, eliminating stasis to stop pain.

Treatment by Chinese herbs gingivitis pertinent literature report is more, but the disclosed medicine flavour of a drug of great majority are various, and a lot of Chinese crude drug obtains difficulty, the formula difficulty of medicine is larger, such as Chinese invention patent application number: 201310113802.9 1 kinds of Chinese medicine compositions being used for the treatment of gingivitis, it is made up of following 24 taste Chinese crude drugs: Gypsum Fibrosum, Radix Liriopes, Herba Houttuyniae, Myrrha, Semen Arecae, Fructus Crataegi, Radix Paeoniae Rubra, Folium Et Cacumen Murrayae, Radix et Rhizoma Rhei (stir-fried with wine), Rhizoma Coptidis, Radix Asparagi, Radix Achyranthis Bidentatae, Rhizoma Cimicifugae, Caulis Mahoniae, dried Alumen, Radix Panacis Quinquefolii, Cacumen Platycladi, Radix Rubiae, Herba Sarcandrae, Herba Lycopi, Folium Ilicis Cornutae, Caulis Trachelospermi, the Radix Angelicae Dahuricae, Flos Lonicerae.Application number 201210448236.2, relate to a kind of medicament for the treatment of gingivitis, it is made up of following 15 taste raw material medicaments in part by weight meters: Herba Hedyotidis Diffusae 10-20 part, Cortex Periplocae 20-30 part, Herba Lophatheri 10-30 part, Calyx Seu Fructus Physalis 20-50 part, Concretio silicea Bambusae seu schizostachyi 5-15 part, Semen Hydnocarpi 5-15 part, Rhizoma Acori Graminei 5-10 part, Cortex Dictamni 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, CitrusaurantiumL.Var.amara Engl. 1-10 part, Semen Vaccariae 5-15 part, Herba Centipedae 10-20 part, Radix Polygalae 10-20 part, Radix Ophiopogonis 10-20 part and Flos Lonicerae 5-15 part.

Summary of the invention:

For the shortcoming that Chinese medicine exists, the object of the invention is to provide that a kind of formula is simple, and raw material is easy to get, and has the Chinese medicine composition and preparation method thereof for the treatment of gingivitis of expelling wind and removing dampness, anti-inflammation and sterilization, the removing toxic substances that expels the heat-evil, eliminating stasis to stop pain effect.

The present invention realizes above-mentioned purpose by following technical solution:

Treat a Chinese medicine composition for gingivitis, it is characterized in that, the raw material making described Chinese medicine composition consists of: Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri, Rhizoma Corydalis.

Wherein, raw material composition and the parts by weight of making described Chinese medicine composition are:

Radix Clematidis 9-29, Rhizoma Drynariae 3-18, Radix Et Rhizoma Rhei 6-27, Ramulus Cinnamomi 3-12, Olibanum 3-12, Herba Cirsii 3-12, Herba Lophatheri 6-18, Rhizoma Corydalis 6-18.

Wherein, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

Radix Clematidis 28, Rhizoma Drynariae 12, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 8, Olibanum 8, Herba Cirsii 3, Herba Lophatheri 6, Rhizoma Corydalis 12.

Wherein, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

Radix Clematidis 12, Rhizoma Drynariae 6, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 6, Herba Lophatheri 18, Rhizoma Corydalis 18.

Wherein, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

Radix Clematidis 18, Rhizoma Drynariae 18, Radix Et Rhizoma Rhei 18, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 12, Herba Lophatheri 12, Rhizoma Corydalis 8.

Medical material selected by the present invention and pharmacology as follows:

Radix Clematidis:

Meridian distribution of property and flavor: pungent, salty, temperature.Return urinary bladder channel.

Function cures mainly: wind-damp dispelling, removing obstruction in the collateral to relieve pain, and disappear a fishbone or other bone caught in the throat.Be mainly used in rheumatism arthromyodynia, fishbone caught in throat, traumatic pain, headache, toothache, gastric abscess, and phlegm retention, dysphagic, Fu Nv mass in the abdomen amass block, lump in breast etc.

Rhizoma Drynariae:

Meridian distribution of property and flavor: bitter, temperature.Return liver, kidney channel.

Function cures mainly: continuous wound of invigorating blood circulation, the kidney invigorating bone strengthening.Be mainly used in traumatic injury or wound, bones and muscles injury, the stagnant pain of the stasis of blood, lumbago due to renal deficiency flaccidity of the lower limbs, Hiccough and deaf, toothache, chronic diarrhea etc.

Radix Et Rhizoma Rhei:

Meridian distribution of property and flavor: bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.

Function cures mainly: heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be mainly used in stagnant constipation, delirium is gone mad ， lumps in the chest and abdomen, and heat in blood tells nosebleed, conjunctival congestion pharyngeal swelling, pathopyretic ulcer, burn and scald, all cards of blood stasis amenorrhea, hygropyretic dysentery, jaundice, edema stranguria etc.

Ramulus Cinnamomi:

Meridian distribution of property and flavor: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.

Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.Be mainly used in the cards such as anemofrigid cold, all pain cards of congealing cold with blood stasis, phlegm retention, syndrome of water-retention, cardiopalmus.

Olibanum:

Meridian distribution of property and flavor: pungent, bitter, temperature.GUIXIN, liver, spleen channel.

Function cures mainly: blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.Be mainly used in all pain cards of stagnation of blood stasis, as trusted subordinate's pain, dysmenorrhea, postpartum stagnation stomachache, rheumatic arthralgia, lumps in the chest and abdomen, traumatic injury, skin infection carbuncle etc.

Herba Cirsii:

Meridian distribution of property and flavor: sweet, bitter, cold.GUIXIN, Liver Channel.

Function cures mainly: cooling blood for hemostasis, dissipating blood stasis removing toxicity for eliminating carbuncles.The heat in blood such as nosebleed, hematuria, metrorrhagia of telling be mainly used in caused by the absurd row of heat in blood forcing blood go out blood disorder, the carbuncle sore tumefacting virus that burning hot poison is contained.

Herba Lophatheri:

Meridian distribution of property and flavor: sweet, light, cold.GUIXIN, stomach, small intestine meridian.

Function cures mainly: clearing away heat-fire, relieving restlessness, diuresis.Be mainly used in calentura excessive thirst, aphtha dark coloured urine, the puckery pain of pyretic stranguria etc.Doctor trained in Western medicine is examined as the herpetic stomatitis person that belongs to flaming up of heart-fire, and urinary system infection etc. belong to part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels intenseness of heat person.

Rhizoma Corydalis:

Meridian distribution of property and flavor: pungent, bitter, temperature.GUIXIN, liver, spleen channel.

Function cures mainly: invigorate blood circulation, circulation of qi promoting, pain relieving.Be mainly used in the various pain cards caused by stagnation of QI-blood.As obstruction of qi in the chest and cardialgia, stomachache due to hyperactive liver-QI attacking the stomach, dysmenorrhea, menoxenia, the stagnant stomachache of the stasis of blood in puerperal, colic of cold type stomachache, traumatic injury, pain caused by ecchymoma, rheumatic arthralgia etc.

The traditional Chinese medical science thinks that gingivitis, gingival swelling and pain mostly are that the evil poison of wind and cold is invaded, cold-evil solidifyingly closes, venation impatency causes.In side, the pungent loose temperature general character of Radix Clematidis is violent, and be apt to away not keep, a surname for wind medicine leads kind passerby, can drive away the wind at table, and can change again inner wet, sensible meridians, can lead and can declare.Radix Clematidis temperature three-way meridian, wind-expelling pain-stopping; Rhizoma Drynariae warming kidney and promoting blood circulation, bone and muscle strengthening pain relieving.Two medicine compatibilities, then wind-damp dispelling and the kidney invigorating use, the effect of bone and muscle strengthening, wind-damp dispelling, stopping numbness pain is better.Radix Et Rhizoma Rhei is bitter and partially fall, and cold energy heat-clearing and toxic substances removing, had both entered edema caused by disorder of QI, and entered again blood system, sedimentation defecating feces excretion can be borrowed to make the pathogenic fire pyretic toxicity of inflammation obtain following letting out, have the merit of purging fire and cooling blood removing toxic substances.The pungent loose temperature of Ramulus Cinnamomi is led to, and expelling wind and cold, treats numbness pain relieving, has promoting the flow of QI-blood by warming the meridian, the effect of dispersing cold for relieving pain, can the cold and cool drug induced injury taste such as Radix Et Rhizoma Rhei in the side of alleviation.The pungent perfume (or spice) of Olibanum is walked to alter, and bitter in the mouth is removed heat by catharsis, and enters conscience two through blood system, can eliminating stasis to stop pain, and eliminating carbuncle of invigorating blood circulation again, putrefaction-removing granulation-promoting is external wounds key medicine.Herba Cirsii cooling blood for hemostasis, dissipating blood stasis removing toxicity for eliminating carbuncles.Herba Lophatheri sweet in the mouth and trembling with fear, the sharp key of light energy, therefore can clearing away heart-fire, relieving thirst and restlessness, eliminating dampness by diuresis heat, except stomach-fire, reach flesh table, separate pathogenic heat.The property that the pungent loose hardship cooling of Rhizoma Corydalis is logical, both entered blood system, entered edema caused by disorder of QI again.Can gas in promoting the circulation of blood, again can blood in circulation of qi promoting.Energy repercussive blood, loose stagnant gas, relieve the pain pain, is the good medicine of blood-activating and qi-promoting pain relieving.Full side shares can cooperative interaction mutually, play expelling wind and removing dampness altogether, the removing toxic substances that expels the heat-evil, eliminating stasis to stop pain, promoting blood circulation and detumescence, anastaltic effect, thus play and treat gingivitis effect.

Another object of the present invention is to provide a kind of preparation method for the treatment of the Chinese medicine composition of gingivitis, it is characterized in that comprising following steps:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 6-12 times of water gaging, soaks, and decocts, and filters, and second time adds 4-8 times of water gaging, decocts, and filters, and third time adds 3-6 times of water gaging, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) extractum of gained filtrate reduced in volume to relative density 1.10-1.25 when being 60 DEG C;

4) by step 3) pulverizing of gained extract dry, add pharmaceutic adjuvant, be prepared into oral formulations.

Above-described oral formulations can be capsule, tablet, granule, powder, pill, buccal tablet, spray, oral liquid.

Compared with existing medicine, the Chinese medicine composition that the present invention treats gingivitis has following technique effect:

1, prescription flavour of a drug of the present invention are simplified, and formula is simple, flavour of a drug wide material sources.

2, treat short treating period, effective percentage is high, does not recur more, the advantage had no drug resistance, and can significantly improve gingival index and plaque index.

Detailed description of the invention:

The present invention is further illustrated below by embodiment.Should be understood that, following detailed description of the invention, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

Embodiment 1 capsule

Prescription (with parts by weight):

Radix Clematidis 28, Rhizoma Drynariae 12, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 8, Olibanum 8, Herba Cirsii 3, Herba Lophatheri 6, Rhizoma Corydalis 12.

Preparation method:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 8 times of water gagings, soaks, and decocts, and filters, and second time adds 6 times of water gagings, decocts, and filters, and third time adds 4 times of water gagings, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) gained filtrate reduced in volume to relative density when being 60 DEG C 1.20 extractum;

4) by step 3) pulverizing of gained extract dry, add starch, alcohol granulation, dry, filling capsule, every containing crude drug 0.5g.

Embodiment 2 oral liquid

Prescription (with parts by weight):

Radix Clematidis 12, Rhizoma Drynariae 6, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 6, Herba Lophatheri 18, Rhizoma Corydalis 18.

Preparation method:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 12 times of water gagings, soaks, and decocts, and filters, and second time adds 8 times of water gagings, decocts, and filters, and third time adds 6 times of water gagings, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) gained filtrate reduced in volume to relative density when being 60 DEG C 1.15 extractum;

4) by step 3) gained extractum adds correctives, and antiseptic is prepared into oral liquid, makes milliliter contained 0.1g.

Embodiment 3 buccal tablet

Prescription (with parts by weight):

Radix Clematidis 18, Rhizoma Drynariae 18, Radix Et Rhizoma Rhei 18, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 12, Herba Lophatheri 12, Rhizoma Corydalis 8.

Preparation method:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 6-12 times of water gaging, soaks, and decocts, and filters, and second time adds 4-8 times of water gaging, decocts, and filters, and third time adds 3-6 times of water gaging, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) extractum of gained filtrate reduced in volume to relative density 1.10-1.25 when being 60 DEG C;

4) by step 3) pulverizing of gained extract dry, add aspartame, polyvidone, granulate, add magnesium stearate, tabletting, obtain buccal tablet, every sheet is containing crude drug 1g.

Embodiment 4 pill

Prescription (with parts by weight):

Radix Clematidis 28, Rhizoma Drynariae 12, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 8, Olibanum 8, Herba Cirsii 3, Herba Lophatheri 6, Rhizoma Corydalis 12.

Preparation method:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 8 times of water gagings, soaks, and decocts, and filters, and second time adds 5 times of water gagings, decocts, and filters, and third time adds 5 times of water gagings, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) gained filtrate reduced in volume to relative density when being 60 DEG C 1.15 extractum;

4) by step 3) pulverizing of gained extract dry, with water pill, dry, to obtain final product.

Clinical experimental data

1. physical data

Choose gingivitis patients 208 example in my the center year February in January, 2013 to 2015 of going to a doctor, all with reference to the diagnostic criteria about gingivitis in " oral medicine " the 4th edition, be divided into experimental group and matched group at random.

Experimental group 104 example, wherein man 64 example, female 40 example, 15 ~ 60 years old age (average 36.3 years old), the course of disease 15 days ~ 10 years (average 3.2 years).

Matched group 104 example, wherein man 65 example, female 39 example, 15 ~ 60 years old age (average 36.5 years old), the course of disease 14 days ~ 10 years (average 3.1 years).

Two groups of patients through statistical procedures no significant difference (P > 0.05), have comparability in sex, age, the course of disease.

2. include in and exclusion standard

Inclusive criteria:

1. whole body health is in order, without serious systemic disease, as hematopathy, diabetes, hyperthyroidism, acquired immune deficiency syndrome (AIDS), cardiovascular disease, cancer etc., and 15 ~ 65 years old age.

2. marginal gingivitis, the hepertrophic gingivitis in papillary gingivitis, acute multiple gingival abscess and the chronic gingivitis in acute gingivitis is selected.

3. Chinese medical discrimination belongs to excessiveness of stomach-fire or deficiency of kidney-YIN, hyperactivity of deficient fire person, and namely red swelling of gingiva hemorrhage, halitosis, red tongue with yellow fur, slippery and rapid pulse is main symptom person.

4. antibacterials person is not used medical the last week.5. patient's informed consent, be ready to give one's cooperation further consultation person.

Case exclusion standard:

1. with serious systemic disease, Pregnant and lactant women.

2. allergic constitution patient.

3. suffer from Other diseases need use antibacterials or follow up a case by regular visits to difficult person.

4. in oral analgesic drug product in 12h, or 6h, local uses medicine.

5. 1 week domestic demand oral temperaturing injecting-ability Chinese medicine person.

3. Therapeutic Method

Experimental group gives capsule treatment prepared by the embodiment of the present invention 1, and every day 3 times, each 4 7th is a course for the treatment of.

Matched group gives compound recipe hibitane collutory, and every milliliter containing Fructus Vitis viniferae chlorhexidine 1.2mg and metronidazole 0.2mg.Each rinsing the mouth is about 15ml.Sooner or later after brushing teeth, rinsing the mouth 2-5 minutes, 7th is a course for the treatment of.

7d observed and recorded before the treatment and after medication.Cure patient and follow the tracks of return visit 6 months.

4. observation index clinical symptoms: gingiva local pain, hemorrhage, color, swelling and pyorrhea situation.Toposcopy: comprise plaque index, sulcular bleeding index.Untoward reaction is recorded at any time in therapeutic process.

5. criterion of therapeutical effect with reference to Cao Caifang chief editor " periodontal " draft into:

Cure: pain disappears, and plaque index and sulcular bleeding index all drop to 0, and gingival abscess disappears, outward appearance recovers normal;

Effective: pain relief, plaque index and sulcular bleeding index all drop to 1, and gingival abscess disappears, and outward appearance recovers normal substantially;

Effective: pain relief, plaque index and sulcular bleeding index all drop to 2 or 3, and outward appearance makes moderate progress;

Invalid: sings and symptoms is without significant change.

6. experimental result

See table 1.

Table 1 liang group Clinical efficacy comparison

Group

Number of cases

Cure (cure rate)

Effective

Effectively

Invalid

Total effective rate

Matched group

104

12(11.5％)

22

28

42

59.6％

Experimental group

104

60(57.7％)

24

14

6

94.2％

Visible experimental group cure rate is 57.7%, and the cure rate of matched group is 11.5%; Experimental group total effective rate is 94.2%, and matched group total effective rate is only 59.6%.Analyze through two groups of Ridit be similar to, the curative effect of experimental group and matched group has significant differences (P < 0.01), illustrates that Chinese medicine of the present invention is in the treatment of gingivitis, achieves significant therapeutic effect.

Clinical observation finds, Chinese medicine of the present invention has sterilization and reduces bacterial plaque formation rate and antiinflammation, significantly can improve gingival hemorrhage, gingiva pain, the gingivitis such as swelling and aching of gum and halitosis symptom.

In whole Ureteral Calculus process, all there is not toxicity in two groups of all patients.Within 6 months, pay a return visit display experimental group and cure patient, no case was recurrence, and relapse rate is 0, and matched group healing Patients on Recurrence rate is about 40%.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, example is executed in the equivalence that any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (7)

1. treat a Chinese medicine composition for gingivitis, it is characterized in that, the raw material making described Chinese medicine composition consists of: Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri, Rhizoma Corydalis.

2. the Chinese medicine composition for the treatment of gingivitis as claimed in claim 1, is characterized in that, raw material composition and the parts by weight of making described Chinese medicine composition are:

Radix Clematidis 9-29, Rhizoma Drynariae 3-18, Radix Et Rhizoma Rhei 6-27, Ramulus Cinnamomi 3-12, Olibanum 3-12, Herba Cirsii 3-12, Herba Lophatheri 6-18, Rhizoma Corydalis 6-18.

3. the Chinese medicine composition for the treatment of gingivitis as claimed in claim 2, is characterized in that, raw material composition and the parts by weight of making described Chinese medicine composition are:

Radix Clematidis 28, Rhizoma Drynariae 12, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 8, Olibanum 8, Herba Cirsii 3, Herba Lophatheri 6, Rhizoma Corydalis 12.

4. the Chinese medicine composition for the treatment of gingivitis as claimed in claim 2, is characterized in that, raw material composition and the parts by weight of making described Chinese medicine composition are:

Radix Clematidis 12, Rhizoma Drynariae 6, Radix Et Rhizoma Rhei 24, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 6, Herba Lophatheri 18, Rhizoma Corydalis 18.

5. the Chinese medicine composition for the treatment of gingivitis as claimed in claim 2, is characterized in that, raw material composition and the parts by weight of making described Chinese medicine composition are:

Radix Clematidis 18, Rhizoma Drynariae 18, Radix Et Rhizoma Rhei 18, Ramulus Cinnamomi 6, Olibanum 6, Herba Cirsii 12, Herba Lophatheri 12, Rhizoma Corydalis 8.

6. a preparation method for Chinese medicine composition as described in as arbitrary in claim 1-5, is characterized in that, comprise following steps:

1) take and get Radix Clematidis, Rhizoma Drynariae, Radix Et Rhizoma Rhei, Ramulus Cinnamomi, Olibanum, Herba Cirsii, Herba Lophatheri and Rhizoma Corydalis, pulverize, mixing, for subsequent use;

2) by step 1) gained medicated powder decocts with water three times, and first time adds 6-12 times of water gaging, soaks, and decocts, and filters, and second time adds 4-8 times of water gaging, decocts, and filters, and third time adds 3-6 times of water gaging, decocts, and filters, discarded medicinal residues, merging filtrate;

3) by step 2) extractum of gained filtrate reduced in volume to relative density 1.10-1.25 when being 60 DEG C;

4) by step 3) gained extractum is prepared into oral formulations.

7. the Chinese medicine composition for the treatment of gingivitis as claimed in claim 6, it is characterized in that, described oral formulations can be capsule, tablet, granule, powder, pill, buccal tablet, spray, oral liquid.