CN110072857A - 作为造血前列腺素d合酶抑制剂的1,3-二取代的环丁酮或氮杂环丁烷衍生物 - Google Patents

作为造血前列腺素d合酶抑制剂的1,3-二取代的环丁酮或氮杂环丁烷衍生物 Download PDF

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CN110072857A
CN110072857A CN201780075127.1A CN201780075127A CN110072857A CN 110072857 A CN110072857 A CN 110072857A CN 201780075127 A CN201780075127 A CN 201780075127A CN 110072857 A CN110072857 A CN 110072857A
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trans
thiazol
yloxy
cyclobutanecarboxamide
substituted
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Chinese (zh)
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D.N.迪顿
Y.郭
A.P.汉考克
C.舒尔特
B.G.希勒
E.D.史密斯
E.L.斯图尔特
S.A.汤姆森
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GlaxoSmithKline Intellectual Property Development Ltd
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GlaxoSmithKline Intellectual Property Development Ltd
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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CN201780075127.1A 2016-10-13 2017-10-12 作为造血前列腺素d合酶抑制剂的1,3-二取代的环丁酮或氮杂环丁烷衍生物 Pending CN110072857A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662407634P 2016-10-13 2016-10-13
US62/407,634 2016-10-13
PCT/IB2017/056320 WO2018069863A1 (en) 2016-10-13 2017-10-12 1,3 di-substituted cyclobutane or azetidine derivatives as hematopoietic prostaglandin d synthase inhibitors

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CN110072857A true CN110072857A (zh) 2019-07-30

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US (1) US11053234B2 (https=)
EP (1) EP3526206A1 (https=)
JP (1) JP6938628B2 (https=)
KR (1) KR20190072565A (https=)
CN (1) CN110072857A (https=)
AR (1) AR109931A1 (https=)
AU (1) AU2017342156B2 (https=)
BR (1) BR112019007609A2 (https=)
CA (1) CA3038756A1 (https=)
CL (1) CL2019000986A1 (https=)
CO (1) CO2019003482A2 (https=)
CR (1) CR20190174A (https=)
DO (1) DOP2019000087A (https=)
EA (1) EA201990904A1 (https=)
IL (1) IL265597A (https=)
JO (1) JOP20190072A1 (https=)
MA (1) MA46531A (https=)
MX (1) MX2019004320A (https=)
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PH (1) PH12019500811A1 (https=)
TW (1) TW201827412A (https=)
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Cited By (4)

* Cited by examiner, † Cited by third party
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CN111549000A (zh) * 2020-06-18 2020-08-18 中国医学科学院整形外科医院 一种过表达Hpgds的重组脂肪干细胞、制备方法及其应用
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CN113582880A (zh) * 2020-04-30 2021-11-02 南京药石科技股份有限公司 一种（3-氨基二环[1.1.1]戊烷-1-基）氨基甲酸叔丁酯的制备方法
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