CN110051791A - A kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof - Google Patents
A kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof Download PDFInfo
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- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
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- A23F3/18—Extraction of water soluble tea constituents
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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Abstract
A kind of prevention and treatment respiratory disease Chinese medicine composition of the present invention and preparation method thereof, it is the selected 10 taste medicinal materials including traditional dual-purpose of drug and food such as lily, almond, dried orange peel, Radix Glycyrrhizae, Pu'er tea, the functional food beverage being formulated through scientific method has clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum effect.It takes for a long time, helps and propose healthy tendency, effectively antagonize smoking, haze etc. to the harm of human body bring and discomfort.
Description
Technical field
The invention belongs to the Technical Development Areas of traditional Chinese medicine health care product, and in particular in a kind of prevention and treatment respiratory disease
Drug composition and preparation method thereof.
Background technique
Smoking, is not only detrimental to health, can also have a adverse impact to society.Contain toxin nicotine in tobacco leaf,
Also it is nicotine, the nicotine of 1 grammes per square metre can poison 300 rabbits or 500 mouse with poison, if injecting 50 milligrams of nicotine, Jiu Huizhi to people
Extremely.Smoking endangers respiratory tract maximum, it is easy to cause laryngitis, tracheitis, the coughs such as pulmonary emphysema.When smoking cigarette from
Mouthful enter, by throat, trachea-bronchial epithelial cell, into blood.
Haze seriously affects people's health generation, and haze typically refers to that diameter in air is not more than 2.5 microns
Grain object, these particulate matters are due to that directly can suck lung by human body, to cause to seriously threaten to human respiratory, when long
Between in PM 2.5 it is excessively high in the case where, the morbidity risk rate of lung cancer can be improved.
How because of smoking or haze weather caused by respiratory disease is prevented and treated? the present inventor uses traditional medicine
Eat dual-purpose, including the 10 taste medicinal material such as lily, almond, dried orange peel, Radix Glycyrrhizae, Pu'er tea has been formulated a kind of functional food beverage,
Has the effect of good clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum.Take for a long time, help and propose healthy tendency, effectively antagonize smoking,
Haze etc. is endangered to human body bring and discomfort.
Lily is Liliaceae lilium perennial herb bulbous plant, native to China, be mainly distributed on east Asia,
The Northern Hemisphere Temperate Region in China such as Europe, North America, it is edible, also make medicinal.Lily not only has the function of good nutritious tonifying, but also
Also there is certain preventive and therapeutic effect to a variety of Seasonal diseases caused by dry in autumn, says that fresh lily bulb has nourishing heart in Chinese medicine
The effect of tranquilizing the mind, moistening lung to arrest cough, the main deficiency of Yin is coughed long；Blood-stained sputum；The pyreticosis later period；Waste heat is not clear or feelings will it is unsuccessful caused by void
It is tired palpitation with fear, insomnia and dreamful sleep, absent-minded；Carbuncle swells；The symptoms such as wet sore.
Gingko, it is sweet in flavor, it is slight bitter, puckery, it is warm-natured.With promote the production of body fluid, quench the thirst, heat-clearing and other effects, it is edible, can also be used as medicine.Chinese medicine
Think, there is gingko unobstructed blood vessel, protection liver, improvement cerebral function, profit skin, anti-aging, treatment senile dementia, brain to supply
Blood deficiency, astringing lung-QI gas, determine phlegm asthma, check with turbidity, antidiarrheal let out, detoxify, reducing just, cure mainly asthma phlegm cough, leukorrhagia gonorrhoea, urine frequency
The illnesss such as number, the enuresis.
Reed root, it is sweet, it trembles with fear.It attaches to the lung and stomach meridians.It is edible, it can also be used as medicine, there is clearing heat-fire, promote the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting,
Diuresis and other effects.For pyreticosis and polydipsia, stomach hot vomiting, cough with lung heat, lung carbuncle pyemesis, the illnesss such as puckery pain of heat gonorrhea.
Almond is the seed of rosaceae apricot, mainly contains protein, fat, sugar, micro amarogentin.It is edible, it can also
It is used as medicine.Return lung, spleen, large intestine channel have the effects of relieving cough and asthma, relax bowel and defecation.
Dried orange peel, it is bitter, pungent, it is warm-natured.Return lung, the spleen channel.It is edible, it can also be used as medicine.With regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm function
Effect is mainly used for preventing and treating abdominal fullness and distention, and deficiency of food is vomited and diarrhoea, the illnesss such as coughing with a lot of sputum.
Lotus leaf, mild-natured, return heart, Liver Channel.It is edible, it can also be used as medicine, with clear away heart-fire relieving summer-heat, dissipating stasis and stanching bleeding, disappear wind clearing damp
Effect, cures mainly hot summer weather polydipsia, pediatric epilepsy scared, and the inverse stupor of married woman's blood gets injured by a fall spitting blood, irregular menstruation, metrorrhagia and metrostaxis, the diseases such as wet sore scabies
Disease.
Peppermint, popular name are Lamiaceae plant " lunar caustic grass ", that is, belong to other drying herbs, edible, can also be used as medicine.
With pungent cool property sweating and heat resolving effect, the diseases such as influenza, headache, hot eyes, body heat, throat, gum swelling and pain are cured mainly.External application can
Control neuralgia, pruitus, fash and eczema etc..
Elscholtiza, pungent, tepor enter lung, stomach meridian.It is edible, it can also be used as medicine.With sweating, row water dissipate it is wet, in warm stomach tune
The effects of.It is cold to cure mainly the cold drink of Xia Yue sense, has a headache and fever, aversion to cold is lossless, feeling of stuffiness in chest abdominal pain, vomiting and diarrhoea, the illnesss such as hot summer weather cough.
Pu'er tea, having reduces blood lipid, weight-reducing, antibacterial aid digestion, warm stomach, promotes the production of body fluid, quenches the thirst, a variety of function such as removing toxic substances of sobering up
Effect.Can clearing stomach promote the production of body fluid, eliminate indigestion and phlegm, removing toxic substances of relieving the effect of alcohol, diuresis cold dispelling, it is relieving cough and reducing sputum, reduce lipid cholesterol the effects of.
Radix Glycyrrhizae is sweet in flavor, mild-natured, return heart, lung, spleen, stomach meridian.It is edible, it can also be used as medicine.It is clearing heat and detoxicating with invigorating the spleen and benefiting qi,
The effects of expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.It is weakness of the spleen and the stomach for treating, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum,
Stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, it is strong all the effects of.
Above-mentioned all medicines share has the effect of clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum.It takes for a long time, helps and mention just
Gas effectively antagonizes smoking, haze etc. and endangers to human body bring.
Summary of the invention
A kind of prevention and treatment respiratory disease Chinese medicine composition of the present invention and preparation method thereof is selected traditional medicine food
10 dual-purpose taste medicinal materials, the functional food beverage being prepared through scientific method have clearing heat and detoxicating, Yin nourishing and lung moistening, cough-relieving
The effect of phlegm.It takes for a long time, helps and propose healthy tendency, effectively antagonize smoking, haze etc. to the harm of human body bring and discomfort.
The present invention is realized through following technical proposals:
A kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof, is by the raw material of following parts by weight
Composition: 100-150 parts of lily, 100-150 parts of gingko, 100-150 parts of reed root, 80-100 parts of almond, 80-100 parts of dried orange peel, lotus leaf
30-70 parts, 80-100 parts of peppermint, 80-100 parts of elscholtiza, 30-70 parts of Pu'er tea, 30-70 parts of Radix Glycyrrhizae.
It is a kind of prevent and treat respiratory disease Chinese medicine composition and preparation method thereof can also be by following parts by weight
Raw material composition: 120-140 parts of lily, 120-140 parts of gingko, 120-140 parts of reed root, 85-95 parts of almond, 85-95 parts of dried orange peel,
40-60 parts of lotus leaf, 85-95 parts of peppermint, 85-95 parts of elscholtiza, 40-60 parts of Pu'er tea, 40-60 parts of Radix Glycyrrhizae.
A kind of Chinese medicine composition and preparation method thereof preventing and treating respiratory disease is preferably and by following parts by weight
Raw material composition: 135 parts of lily, 135 parts of gingko, 135 parts of reed root, 90 parts of almond, 90 parts of dried orange peel, 54 parts of lotus leaf, peppermint 90
Part, 90 parts of elscholtiza, 54 parts of Pu'er tea, 54 parts of Radix Glycyrrhizae.
A kind of prevention and treatment respiratory disease Chinese medicine composition of the present invention and preparation method thereof, preparation method includes
Following steps:
(1) it takes the dried orange peel in the raw material composition of any of the above-described parts by weight, peppermint to set multi-functional mention and boil in tank, adds 14-16 times
Water is measured, stops distillation until distillate is tasteless with extraction by steam distillation volatile oil, a certain amount of spit is added in gained volatile oil
Temperature -80 is ground to package completely, and the aqueous solution after obtaining volatile oil package liquid, with distillation is distinguished another device and saved, spare；
(2) eight taste medicinal materials of the dregs of a decoction and other parts by weight after said extracted volatile oil are added in extractor, add decocting
It boils twice, the aqueous solution and water supplement after above-mentioned distillation is added for the first time are measured to 10-12 times, are decocted 2-3 hour, add water second
8-10 times is measured, and is decocted 1-2 hours, and decoction liquor twice is merged, and filtering obtains filtered fluid, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
It is prepared into oral liquid:
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.1-1.0% preservative, 0.1-30% is added
Corrigent, add water to be configured to 1000-2000 parts of solution, stir, filtering, it is filling to get.
The gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, refers to and will volatilize oily a small amount of second
After alcohol dissolution, Tween-80 is added and is ground to molten condition.
The preservative includes benzoic acid, sodium benzoate, sorbierite, the one or more of above mixtures of sorbic acid.
The corrigent includes sucrose, lactose, fructose, Steviosin, Aspartame, strawberry essence, orange essence, hawthorn perfume
One of essence, citric acid are a variety of.
Filtering described in preparation method (2) refers to 80-100 mesh net filtration.
Filtering described in preparation method (4) refers to the filtering with microporous membrane with 0.25-0.60um.
A kind of prevention and treatment respiratory disease Chinese medicine composition of the present invention and preparation method thereof, preparation method is preferred
With:
(1) 90 parts of dried orange peel are taken, multi-functional mention is set for 90 parts of peppermint and boils in tank, adds 15 times of amount water, uses extraction by steam distillation
Volatile oil stops distillation until distillate is tasteless, and gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, must wave
Hair oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction with 135 parts of lily, 135 parts of gingko, 135 parts of reed root, 90 parts of almond,
54 parts of lotus leaf, 90 parts of elscholtiza, 54 parts of Radix Glycyrrhizae, in 54 parts of addition extractors of Pu'er tea, add water to cook twice, are added for the first time
Aqueous solution and water supplement after stating distillation decoct 2 hours, for the second time plus 10 times of water amounts, decoction 1 hour merge two to 12 times of amounts
Secondary decoction liquor obtains filtered fluid with 100 mesh net filtrations, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.5% sodium benzoate and 0.3% lemon is added
Acid adds water to be configured to 2000 parts of solution, stirring, with 0.25um filtering with microporous membrane, it is filling to get.
It is prepared into solid orally ingestible:
Clear cream obtained in above-mentioned preparation method (3) is taken, fine powder is dried, crushed into, and takes above-mentioned volatile oil package liquid, it can
It is prepared into tablet by the preparation method of tablet, capsule can also be prepared by the preparation method of capsule, it can also be by granule
Preparation method is prepared into granule.
It is of the invention a kind of with prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof, the Chinese traditional medicine composition
Object has the effect of clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum, takes for a long time, helps and propose healthy tendency, effectively antagonize smoking, haze
Deng to the harm of human body bring and discomfort.
Beneficial effect
It includes hundred that a kind of prevention and treatment respiratory disease Chinese medicine composition of the present invention and preparation method thereof, which is selected,
10 taste medicinal materials of the tradition dual-purpose of drug and food such as conjunction, almond, dried orange peel, Radix Glycyrrhizae, Pu'er tea, the functional food being formulated through scientific method
Beverage is savored, there is clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum effect.It takes for a long time, helps and propose healthy tendency, effectively antagonize smoking, mist
Haze etc. is endangered to human body bring and discomfort.
Specific embodiment
Embodiment 1 (prepares oral liquid)
(1) 80 parts of dried orange peel are taken, multi-functional mention is set for 80 parts of peppermint and boils in tank, add 14-16 times to measure water, mentioned with steam distillation
Volatile oil is taken, until distillate is tasteless, stops distillation, gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, obtains
Volatile oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction with 100 parts of lily, 100 parts of gingko, 100 parts of reed root, 80 parts of almond,
30 parts of lotus leaf, 80 parts of elscholtiza, 30 parts of Radix Glycyrrhizae, in 30 parts of addition extractors of Pu'er tea, add water to cook twice, are added for the first time
Aqueous solution and water supplement after stating distillation decoct 3 hours, for the second time plus 10 times of water amounts, decoction 2 hours merge two to 12 times of amounts
Secondary decoction liquor obtains filtered fluid with 100 mesh net filtrations, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned gained volatile oil package liquid, the clear cream into clean container, 0.1% benzoic acid and 0.1% is added
Steviosin adds water to be configured to 1000 parts, stirring, with 0.25um filtering with microporous membrane, it is filling to get.
Embodiment 2
(1) 90 parts of dried orange peel are taken, multi-functional mention is set for 90 parts of peppermint and boils in tank, adds 15 times of amount water, uses extraction by steam distillation
Volatile oil stops distillation until distillate is tasteless, and gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, must wave
Hair oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction with 135 parts of lily, 135 parts of gingko, 135 parts of reed root, 90 parts of almond,
54 parts of lotus leaf, 90 parts of elscholtiza, 54 parts of Radix Glycyrrhizae, in 54 parts of addition extractors of Pu'er tea, add water to cook twice, are added for the first time
Aqueous solution and water supplement after stating distillation decoct 2 hours, for the second time plus 10 times of water amounts, decoction 1 hour merge two to 12 times of amounts
Secondary decoction liquor obtains filtered fluid with 100 mesh net filtrations, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.5% sodium benzoate and 0.3% lemon is added
Acid adds water to be configured to 2000 parts of solution, stirring, with 0.25um filtering with microporous membrane, it is filling to get.
Embodiment 3
(1) 100 parts of dried orange peel are taken, multi-functional mention is set for 100 parts of peppermint and boils in tank, adds 14 times of amount water, is mentioned with steam distillation
Volatile oil is taken, until distillate is tasteless, stops distillation, gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, obtains
Volatile oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction and 130 parts of lily, 130 parts of gingko, 130 parts of reed root, 90 parts of almond,
45 parts of lotus leaf, 50 parts of Pu'er tea, in 50 parts of addition extractors of Radix Glycyrrhizae, is added water to cook twice, is added for the first time above-mentioned at 90 parts of elscholtiza
Aqueous solution and water supplement after distillation decoct 1.5 hours, for the second time plus 9 times of water amounts, decoction 1.5 hours merge two to 11 times of amounts
Secondary decoction liquor, filtering, obtains filtered fluid, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.2% sodium benzoate and 15% sucrose is added,
Add water to be configured to 1500 parts of solution, stir, with 0.25um membrane filtration, it is filling to get.
Embodiment 4
(1) take 95 parts of dried orange peel, 95 parts of peppermint set multi-functional mention and boil in tank, add 16 times of amount water, use extraction by steam distillation
Volatile oil stops distillation until distillate is tasteless, and gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, must wave
Hair oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction and 140 parts of lily, 140 parts of gingko, 140 parts of reed root, 85 parts of almond,
50 parts of lotus leaf, 50 parts of Pu'er tea, in 60 parts of addition extractors of Radix Glycyrrhizae, is added water to cook twice, is added for the first time above-mentioned at 85 parts of elscholtiza
Aqueous solution and water supplement after distillation decoct 3 hours, for the second time plus 8 times of water amounts, decoction 1 hour, merging are decocted twice to 12 times of amounts
Boil liquid obtains filtered fluid with 120 mesh net filtrations, spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.5% sorbic acid is added and 3% orange is fragrant
Essence adds water to be configured to 2000 parts of solution, stirring, with 0.50um filtering with microporous membrane, it is filling to get.
Embodiment 5
(1) 80 parts of dried orange peel are taken, multi-functional mention is set for 80 parts of peppermint and boils in tank, adds 15 times of amount water, uses extraction by steam distillation
Volatile oil stops distillation until distillate is tasteless, and gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, must wave
Hair oil wraps up the another device preservation of aqueous solution difference after liquid, with distillation, spare；
(2) by after said extracted volatile oil the dregs of a decoction and 150 parts of lily, 140 parts of gingko, 150 parts of reed root, 90 parts of almond,
60 parts of lotus leaf, 90 parts of elscholtiza, 50 parts of Pu'er tea, in 50 parts of addition extractors of Radix Glycyrrhizae, adds water to cook twice, first at 80 parts of peppermint
Aqueous solution and water supplement after the secondary above-mentioned distillation of addition decoct 2 hours to 12 times of amounts, add 8 times of water amounts for the second time, decoction 1 is small
When, merge decoction liquor twice and with 100 mesh net filtrations obtains filtered fluid, it is spare；
(3) clear cream that specific gravity is 1.10~1.20 when above-mentioned filtered fluid being concentrated under reduced pressure into 50~60 DEG C, obtains clear cream, standby
With；
(4) it takes above-mentioned volatile oil package liquid, clear cream into clean container, 0.2% benzoic acid and 0.3% stevia rebaudianum is added
Element adds water to be configured to 1000 parts of solution, stirring, with 0.65um filtering with microporous membrane, it is filling to get.
Embodiment 6
Drug of 2 gained of above-described embodiment after filling is subjected to animal eliminating the phlegm experiment, verifies therapeutic effect of the invention.
Use experimental method for the phenol red method of tracheae: establishing standard curve: precise 0.20g is phenol red, with 5% sodium bicarbonate
Solution is configured to the standard solution of 1000mL.
It chooses Kunming mouse (40), is divided into 5 groups, every group 8,25 ± 2g of weight, haze is simulated using combustion method
Environment, Normal group and model control group carry out physiological saline stomach-filling respectively, and experimental method administration group is divided into high, medium and low three
A dosage group 0.25g/10g, 0.12g/10g, 0.06g/10g, after one week of dosing, phenol is injected intraperitoneally in model group, administration group respectively
Animal is put to death after red solution 0.1ml/10g, 30min, anatomical isolation tracheae is pumped the sodium bicarbonate solution for rinsing respiratory tract, from
The heart measures mouse trap 0D value with ultraviolet specrophotometer, corresponding phenol red concentration is looked on standard curve, measures mouse
Phenols contents, as shown in table 1:
Table 1: phenols contents contrast table
| Group | Quantity (n) | Phenol red excretion concentration |
| Normal group | 8 | 15.33±2.1 |
| Model group | 8 | 25.07±3.25 |
| High dose group | 8 | 21.98±6.62 |
| Middle dose group | 8 | 21.69±2.52 |
| Low dose group | 8 | 19.01±1.74 |
, it can be seen that present invention height, middle dose group have apparent therapeutic effect from table 1.
Embodiment 7
Drug of 2 gained of above-described embodiment after filling is subjected to clinical effectiveness monitoring: being chosen as caused by haze weather
Bronchitis, patient totally 100 of exogenous cough, the patient of every kind of disease 50, wherein male patient 50, female patient 50
Example, age between 20-70 years old, take orally 2 gained drug of embodiment, and 3 times a day, each 20-30ml, exogenous cough 7 days are one
A course for the treatment of, bronchitis two weeks are as a treatment course.Curative effect judging standard is as follows:
It is effective: cough symptom recovery from illness, normal Working Life.
Improve: cough symptom mitigates, normal life.
Invalid: symptom influences normal life without improvement.
2 exogenous cough of table medication Contrast on effect table
| Sample | It is effective | It improves | In vain |
| Embodiment 2 | 89 | 9 | 2 |
Bronchitis medication Contrast on effect table is as shown in table 3:
3 bronchitis of table medication Contrast on effect table
| Sample | It is effective | It improves | In vain |
| Embodiment 2 | 87 | 7 | 6 |
Research has shown that the present invention has good curative effect to cough, bronchitis due to caused by haze weather.
Embodiment 8
Stability test is carried out to above-described embodiment 1 to embodiment 5, investigates the clarity of medical fluid:
Test method: the medical fluid for taking above-described embodiment 1 to prepare to embodiment 6 each 10, every 10ml places 37 DEG C of constant temperature
It in case, monthly checks once, checks 12 months altogether, if it find that one has slight turbid or muddiness or serious in each embodiment
It is muddy, so that it may judgement be carried out in accordance with regulations.(inspection result see the table below).
Clarification indicates that slight turbid is indicated with "+" with "-"；Muddiness is indicated with " ++ "；Serious muddy " +++ " expression.
Conclusion: investigating through stability test, and for embodiment 2 from 1st month to 12nd month, medical fluid remained clarification shape
State, do not find slight turbid or it is muddy phenomena such as；So embodiment 2 is preferred preparation method.
Claims (11)
1. a kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof, which is characterized in that including weighing as follows
Measure the raw material composition of part, 100-150 parts of lily, 100-150 parts of gingko, 100-150 parts of reed root, 80-100 parts of almond, dried orange peel 80-
100 parts, 30-70 parts of lotus leaf, 80-100 parts of peppermint, 80-100 parts of elscholtiza, 30-70 parts of Pu'er tea, 30-70 parts of Radix Glycyrrhizae.
2. a kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof as described in claim 1, feature
It is to be composed of the following raw materials in parts by weight, 120-140 parts of lily, 120-140 parts of gingko, 120-140 parts of reed root, apricot
85-95 parts of benevolence, 85-95 parts of dried orange peel, 40-60 parts of lotus leaf, 85-95 parts of peppermint, 85-95 parts of elscholtiza, 40-60 parts of Pu'er tea, Radix Glycyrrhizae
40-60 parts.
3. a kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof as described in claim 1, feature
Be preferably be composed of the following raw materials in parts by weight, 135 parts of lily, 135 parts of gingko, 135 parts of reed root, 90 parts of almond, dried orange peel
90 parts, 54 parts of lotus leaf, 90 parts of peppermint, 90 parts of elscholtiza, 54 parts of Pu'er tea, 54 parts of Radix Glycyrrhizae.
4. the preparation method as described in claims 1 or 2 or 3, preparation method include the following steps:
4.1 take the raw material of the claims 1 or 2 or 3 any parts by weight form in dried orange peel, peppermint sets multi-functional mention and boils
In tank, add 14-16 times to measure water, stops distillation, gained volatile oil until distillate is tasteless with extraction by steam distillation volatile oil
A certain amount of Tween-80 is added and is ground to package completely, the aqueous solution after obtaining volatile oil package liquid, with distillation is distinguished another device and protected
It deposits, it is spare；
4.2 eight taste medicinal materials of the dregs of a decoction and other parts by weight after said extracted volatile oil are added in extractor, add water to cook two
Secondary, aqueous solution and water supplement after above-mentioned distillation is added for the first time are measured to 10-12 times, are decocted 2-3 hour, add water 8-10 second
It measures, decocts 1-2 hours again, merge decoction liquor twice, filtering obtains filtered fluid, spare；
The clear cream that 4.3 specific gravity when above-mentioned filtered fluid is concentrated under reduced pressure into 50~60 DEG C are 1.10~1.20, obtains clear cream, spare；
4.4 take above-mentioned volatile oil package liquid, clear cream into clean container, 0.1-1.0% preservative is added, 0.1-30% is rectified
Taste agent adds water to be configured to 1000-2000 parts of solution, stir, filtering, it is filling to get.
5. preparation method as claimed in claim 1 or 2 or 3 or 4, preparation method preferably with:
5.1 take 90 parts of dried orange peel, set multi-functional mention for 90 parts of peppermint and boil in tank, add 15 times of amount water, are volatilized with extraction by steam distillation
Oil stops distillation until distillate is tasteless, and gained volatile oil is added a certain amount of Tween-80 and is ground to package completely, obtains volatile oil
Aqueous solution after wrapping up liquid, with distillation is distinguished another device and is saved, spare；
5.2 by after said extracted volatile oil the dregs of a decoction with 135 parts of lily, 135 parts of gingko, 135 parts of reed root, 90 parts of almond, lotus leaf
54 parts, 90 parts of elscholtiza, 54 parts of Radix Glycyrrhizae, in 54 parts of addition extractors of Pu'er tea, add water to cook twice, above-mentioned steaming are added for the first time
Aqueous solution and water supplement after evaporating decoct 2 hours, for the second time plus 10 times of water amounts, decoction 1 hour, merging are decocted twice to 12 times of amounts
Boil liquid obtains filtered fluid with 100 mesh net filtrations, spare；
The clear cream that 5.3 specific gravity when above-mentioned filtered fluid is concentrated under reduced pressure into 50~60 DEG C are 1.10~1.20, obtains clear cream, spare；
5.4 take above-mentioned volatile oil package liquid, clear cream into clean container, and 0.5% sodium benzoate and 0.3% citric acid is added,
Add water to be configured to 2000 parts of solution, stir, with 0.25um filtering with microporous membrane, it is filling to get.
6. the preparation method as described in claim 4 or 5, which is characterized in that a certain amount of Tween-80 grinding is added in gained volatile oil
Completely to package, refer to after will volatilize oil a small amount of ethyl alcohol dissolution, Tween-80 is added and is ground to molten condition.
7. preparation method as claimed in claim 4, which is characterized in that the preservative includes benzoic acid, sodium benzoate, sorb
The one or more of above mixtures of alcohol, sorbic acid.
8. preparation method as claimed in claim 4, which is characterized in that the corrigent include sucrose, lactose, fructose, Steviosin,
One of Aspartame, strawberry essence, orange essence, hawthorn essence, citric acid are a variety of.
9. preparation method as claimed in claim 4, which is characterized in that filtering, which refers to, described in preparation method 4.2 uses 80-100
Mesh net filtration；Filtering described in preparation method 4.4 refers to the filtering with microporous membrane with 0.25-0.60um.
10. preparation method as claimed in claim 4, which is characterized in that clear cream obtained in claim 4 preparation method 4.3 is taken,
It is dried, crushed into fine powder, and takes gained volatile oil package liquid in claim 4.1, can be prepared by the preparation method of tablet in blocks
Agent can also be prepared into capsule by the preparation method of capsule, can also be prepared into granule by process for producing granula.
11. a kind of prevention and treatment respiratory disease Chinese medicine composition and preparation method thereof as described in claims 1 or 2 or 3,
It is characterized in that the Chinese medicine composition has the effect of clearing heat and detoxicating, Yin nourishing and lung moistening, relieving cough and reducing sputum.
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| US20180207215A1 (en) * | 2015-08-21 | 2018-07-26 | Beijing Handian Pharmaceutical Co., Ltd. | Shenlingbaizhu granules and preparation method thereof |
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|---|---|---|---|---|
| CN1085062A (en) * | 1993-10-18 | 1994-04-13 | 逯艳雪 | Strong beverage in Vygen Kangbao County and production technology thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1085062A (en) * | 1993-10-18 | 1994-04-13 | 逯艳雪 | Strong beverage in Vygen Kangbao County and production technology thereof |
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| 林静: "职业保健品新葩——职业保健茶", 《劳动保护》 * |
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| US20180207215A1 (en) * | 2015-08-21 | 2018-07-26 | Beijing Handian Pharmaceutical Co., Ltd. | Shenlingbaizhu granules and preparation method thereof |
| US10813964B2 (en) * | 2015-08-21 | 2020-10-27 | Beijing Handian Pharmaceutical Co., Ltd. | Shenlingbaizhu granules and preparation method thereof |
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