CN110037962A - A kind of face cream of whitening spot-removing - Google Patents
A kind of face cream of whitening spot-removing Download PDFInfo
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- CN110037962A CN110037962A CN201910447435.3A CN201910447435A CN110037962A CN 110037962 A CN110037962 A CN 110037962A CN 201910447435 A CN201910447435 A CN 201910447435A CN 110037962 A CN110037962 A CN 110037962A
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- extract
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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Abstract
The present invention relates to a kind of face cream of whitening spot-removing, the face cream of the whitening spot-removing is made of raw materials such as green-tea extract, Yunnan Camellia extract, Herba Diclipterae Chinensis extract, stephania tetrandra extract, arbutin, licoflavone, niacinamide, orange peel element, tranexamic acid, vitamin C, gallic acid, ceramide, natural plants essence, olive oil.The face cream of whitening spot-removing of the present invention has preferable whitening, nti-freckle, reduces pigmentation.In addition, face cream of the present invention, which additionally aids, repairs impaired skin barrier, it is able to ascend cutaneous immunisation power and protective capacities, extraneous chemical toxicant, ultraviolet light etc. is avoided to reduce the generation of all kinds of skin diseases to the damage of skin histology.
Description
Technical Field
The invention relates to the field of skin care products and cosmetics, in particular to a whitening and freckle removing facial cream.
Background
With the development of society and the improvement of living standard, the functional characteristics of skin care products are more concerned by female consumers. In recent decades, as the environmental pollution is increased, the damage of a large amount of discharged harmful chemicals, irritants, ultraviolet rays and the like to the skin is deepened, and the skin pigmentation and the multiple spots are serious skin problems which afflict vast women, the beauty industry has urgent needs for safe and effective whitening, freckle removing and skin care products.
The invention develops a new face cream with whitening and freckle removing effects by screening and optimizing compatibility of active ingredients for whitening and freckle removing in natural plants.
Disclosure of Invention
The invention aims to provide the face cream which is safe to use and has remarkable effects of whitening, removing freckles and reducing pigmentation.
Tests show that the cream prepared by combining the green tea extract, the camellia yunnanensis extract, the dogliver extract and the tetrandra root extract which are prepared by a specific process with the components of arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide, natural plant extract, olive oil and the like has very good effects of whitening, removing freckles and reducing pigmentation.
The invention relates to a whitening and freckle-removing facial cream which is prepared from the following raw materials in parts by weight:
wherein the natural plant essence is selected from one or more of jasmine essential oil, rose essential oil, gardenia essential oil, sweet osmanthus essential oil, lavender essential oil and jojoba essential oil.
Further, the whitening and freckle-removing facial cream is prepared by the following method:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) the cream is prepared by the steps of adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and natural plants into olive oil, fully stirring to obtain a uniform mixture, then sequentially and slowly adding the green tea extract, the camellia yunnanensis extract, the cynanchum komarovii extract and the tetrandra extract into the mixture while stirring, homogenizing in a high-speed homogenizer after the addition is finished, sterilizing after the homogenization is finished, and subpackaging.
Preferably, the whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
preferably, the weight parts of the raw materials are as follows:
preferably, the weight parts of the raw materials are as follows:
furthermore, the raw materials of the whitening and freckle-removing facial cream also comprise 0.9-1.1 parts by weight of thorn leaf extract.
The thorn leaf extract is prepared by the following steps: rinsing, drying and crushing the overground part of the thorn leaves, soaking the thorn leaves in a 60% baking soda solution for 6 hours, draining, adding a 15 times amount of a mixed solvent of 75% ethanol and ethyl acetate (1: 1.3), soaking for 1 hour, extracting for 1 hour under reflux, filtering, and drying the filtrate in vacuum to obtain the thorn leaf extract.
Preferably, the whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
further, the whitening and freckle-removing facial cream is prepared by the following method:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) rinsing, drying and crushing the overground part of the thorn leaves, soaking the thorn leaves in a 60% baking soda solution for 6 hours, filtering, draining, adding a 15 times of a mixed solvent of 75% ethanol and ethyl acetate (1: 1.3), soaking for 1 hour, extracting for 1 hour under reflux, filtering, and drying the filtrate in vacuum to obtain the thorn leaf extract;
(6) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and lavender essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the Yunnan camellia extract, the dogliver extract, the tetrandra root extract and the thorn leaf extract into the mixture while stirring, homogenizing in a high-speed homogenizer after the addition is finished, sterilizing after the homogenization is finished, and subpackaging to obtain the whitening and freckle-removing facial cream.
Furthermore, the whitening and freckle-removing cream can be prepared into whitening and freckle-removing emulsion or facial mask according to the conventional method in the field.
Further, in the preparation process of the whitening and freckle-removing facial cream, the mixture is put into a high-speed homogenizer for homogenization, intelligent inspection needs to be carried out on the homogenate to judge whether the homogenate meets the requirements, and the specific steps of the inspection are as follows:
s1, extracting 50ML of the homogenate of the uppermost portion of said homogenate 10 times and measuring the weight of said homogenate, respectively, to save as vector X1;
s2, extracting 50ML of the homogenate of the lowermost portion of said homogenate 10 times, and measuring the weight of said homogenate, respectively, to save as vector X2;
s3, respectively calculating the stability of the vector X1 and the vector X2 by using the formula (1);
wherein,S1,s2 is an intermediate parameter，X1iFor the ith value of vector X1, X2iIs the ith value of vector X2, i ═ 1, 2, 3 … 10; t1 is the stability of the vector X1 obtained by calculation, t2 is the stability of the vector X2 obtained by calculation, if the value of t1 or t2 is smaller than-1.33, the homogenization stability test is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, if the test is finished, if the value is not smaller than-1.33, the step is qualified, the test is continuously carried out;
s4, performing homogeneity test by using a formula (2);
wherein QX is the result of the homogeneity test, if QX is more than or equal to 3.02, the homogeneity test is not passed, the homogenate is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, the test is finished, if QX is less than 3.02, the test in the step is qualified, and the subsequent test is continued;
s5, calculating the difference degree of the vector X1 and the vector X2 by using the formula (3);
and if the CY is more than or equal to 2.16, the judgment shows that the differential degree test does not pass, the homogenate is unqualified and needs to be continuously put into a high-speed refiner for homogenate, and if the QX is less than 2.16, the judgment shows that the homogenate passes, the homogenate meets the homogenization requirement and does not need to be continuously put into the high-speed refiner for homogenate.
In addition, the invention also relates to application of the whitening and freckle-removing facial cream in preparation of cosmetics or skin care products.
Licoflavone is a natural whitening agent extracted from specific variety of Glycyrrhrizae radix, and can inhibit tyrosinase activity, dopachrome interconversion and DHICA oxidase activity.
Niacinamide is a derivative of vitamin B3, the most important effect of which in the anti-aging aspect of the skin is to reduce and prevent dullness and yellowing of the skin color during early aging. Niacinamide also repairs the damaged stratum corneum lipid barrier, improving skin resistance. In addition, the niacinamide has the deep water-locking effect, so the skin care product containing the niacinamide has extremely strong water-locking and moisturizing effects.
The olive oil used in the invention is prepared by directly cold pressing fresh olive fruits, does not need heating and chemical treatment, and retains natural nutrient components. Olive oil is considered as the most suitable oil for human nutrition among the oils found so far. The olive oil is rich in squalene with excellent affinity with skin and essential fatty acid of human body, is quickly absorbed, and effectively keeps the skin elastic and moist; the olive oil is rich in monounsaturated fatty acid, vitamin E, K, A, D and other phenolic antioxidant substances, can eliminate facial wrinkles, prevent skin aging, effectively enhance skin elasticity, and has effects of caring skin and hair and preventing hand and foot chap. The carotene and chlorophyll in olive oil endow olive oil with yellow-green color, while chlorophyll plays a role in metabolism, promotes cell growth, and accelerates wound healing. It also helps to beautify the appearance of people and reduce the generation of wrinkles. The oleum Olivarum contains antioxidant for eliminating free radicals, recovering health of viscera and organs, preventing brain aging, and prolonging life.
The green tea extract is an active component extracted from green tea leaves, mainly comprises tea polyphenol, mineral substances, amino acids, vitamins and the like, the structure of the tea polyphenol is rich in phenolic hydroxyl groups, active hydrogen can be provided to inactivate free radicals, free radicals formed by oxidation have higher stability due to a catechol structure, and therefore the tea polyphenol has the effects of eliminating the free radicals and inhibiting lipid peroxidation, and has strong antibacterial effect and skin pigment removal effect as a cosmetic additive.
The camellia yunnanensis is rich in functional components such as unsaturated fatty acid, tea saponin, tea polyphenol, quercetin and the like. The tea saponin is an excellent natural surfactant and has surface activities of emulsification, dispersion, wetting and the like; tea polyphenols as a natural antioxidant can scavenge free radicals, protect cell membrane structure, inhibit histamine release and cytokine production, and resist bacterial and fungal infections. Quercetin can remove active oxygen ROS in human keratinocyte and enhance activity of antioxidant enzyme, thereby achieving antioxidant effect.
The herba Setariae viridis mainly contains volatile oil, fatty acids, flavonoids, steroid saponin, polysaccharide, etc. Flavone, polysaccharide and polyphenol in herba Cibotii have strong ability of eliminating 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical and hydroxyl free radical.
The radix Stephaniae Japonicae extract has effects of eliminating skin inflammation and improving skin allergy. The folium Araliae Elatae extract has antioxidant effect.
The invention takes green tea extract, Yunnan camellia extract, doggie extract, tetrandra root extract and thorn leaf extract which are processed by a specific process as main raw materials, and arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide, natural plant essence, olive oil and the like are added as auxiliary materials to prepare the skin care product with the effects of whitening, removing freckles and reducing pigmentation.
Tests prove that the cream has better effects of whitening, removing freckles and reducing pigmentation, and after a subject continuously uses the cream for 30 days, the facial skin is more white, the pigmentation is obviously reduced, and the spots are lightened. Furthermore, the face cream disclosed by the invention is also beneficial to repairing damaged skin barriers, can improve the immunity and the protective capability of the skin, avoids the damage of external chemical poisons, ultraviolet rays and the like to skin tissues, and reduces the occurrence of various skin diseases.
In addition, as the raw materials of the facial cream are all natural plant extracts or legal skin care product additives, the adding amount of each component also meets the conventional requirements of the production of the facial cream, and the facial cream is safe and reliable to use for a long time.
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention.
Before the present embodiments are further described, it is to be understood that the scope of the invention is not limited to the particular embodiments described below; it is also to be understood that the terminology used in the examples is for the purpose of describing particular embodiments only, and is not intended to limit the scope of the present invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In addition to the specific methods, devices, and materials used in the examples, any methods, devices, and materials similar or equivalent to those described in the examples may be used in the practice of the invention in addition to the specific methods, devices, and materials used in the examples, in keeping with the knowledge of one skilled in the art and with the description of the invention.
Example 1
A whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
the production method comprises the following steps:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and lavender essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the Yunnan camellia extract, the dogliver dish extract and the tetrandra root extract into the mixture while stirring, placing the mixture into a high-speed homogenizer for homogenizing, sterilizing after homogenizing, and subpackaging to obtain the whitening and freckle-removing facial cream.
Example 2
A whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
the production method comprises the following steps:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) rinsing, drying and crushing the overground part of the thorn leaves, soaking the thorn leaves in a 60% baking soda solution for 6 hours, filtering, draining, adding a 15 times of a mixed solvent of 75% ethanol and ethyl acetate (1: 1.3), soaking for 1 hour, extracting for 1 hour under reflux, filtering, and drying the filtrate in vacuum to obtain the thorn leaf extract;
(6) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and gardenia essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the camellia yunnanensis extract, the cynanchum komarovii extract, the tetrandra root extract and the thorn leaf extract into the mixture while stirring, placing into a high-speed homogenizer for homogenizing after the addition is finished, sterilizing after the homogenization is finished, and subpackaging to obtain the whitening and freckle-removing facial cream.
In the preparation process of the whitening and freckle-removing facial cream, a mixture is put into a high-speed homogenizer for homogenizing, intelligent inspection needs to be carried out on the homogenate to judge whether the homogenate meets the requirements, and the specific steps of the inspection are as follows:
s1, extracting 50ML of the homogenate of the uppermost portion of said homogenate 10 times and measuring the weight of said homogenate, respectively, to save as vector X1;
s2, extracting 50ML of the homogenate of the lowermost portion of said homogenate 10 times, and measuring the weight of said homogenate, respectively, to save as vector X2;
s3, respectively calculating the stability of the vector X1 and the vector X2 by using the formula (1);
wherein,S1,s2 is an intermediate parameter, X1iFor the ith value of vector X1, X2iIs the ith value of vector X2, i ═ 1, 2, 3 … 10; t1 is the stability of the vector X1 obtained by calculation, t2 is the stability of the vector X2 obtained by calculation, if the value of t1 or t2 is smaller than-1.33, the homogenization stability test is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, if the test is finished, if the value is not smaller than-1.33, the step is qualified, the test is continuously carried out;
by using the formula (1), the stability of the vector X1 and the stability of the vector X2 can be checked for the first time, if the check cannot meet the requirement of the formula (1), the subsequent check is not needed, and the check efficiency can be greatly improved.
S4, performing homogeneity test by using a formula (2);
wherein QX is the result of the homogeneity test, if QX is more than or equal to 3.02, the homogeneity test is not passed, the homogenate is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, the test is finished, if QX is less than 3.02, the test in the step is qualified, and the subsequent test is continued;
s5, calculating the difference degree of the vector X1 and the vector X2 by using the formula (3);
and if the CY is more than or equal to 2.16, the judgment shows that the differential degree test does not pass, the homogenate is unqualified and needs to be continuously put into a high-speed refiner for homogenate, and if the QX is less than 2.16, the judgment shows that the homogenate passes, the homogenate meets the homogenization requirement and does not need to be continuously put into the high-speed refiner for homogenate.
By utilizing the technology, whether the effect of sufficient homogenization is achieved or not can be intelligently judged for the substances which are added into the high-speed homogenizer for homogenization, so that differences do not exist among all whitening and freckle-removing face creams, the optimal effect can be achieved, meanwhile, the judgment is completely obtained through simple calculation after the quality is obtained, manual intervention is not needed, the workload is greatly reduced, meanwhile, in the judgment process, the judgment is carried out step by step, if the requirements are not met in a certain step, the step after the inspection is not needed, and the inspection efficiency is higher.
Comparative example 1
A whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
the production method comprises the following steps:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing Yunnan camellia, drying, pulverizing, adding 10 times of 15% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain Yunnan camellia extract;
(3) rinsing, drying and crushing the tetrandra root, adding 15 times of 15% ethanol, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain the tetrandra root extract;
(4) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and lavender essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the camellia reticulata extract and the tetrandra root extract into the mixture while stirring, placing the mixture into a high-speed homogenizer for homogenizing after the addition is finished, and sterilizing and subpackaging after the homogenization to obtain the whitening and freckle-removing facial cream.
Comparative example 2
A whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
the production method comprises the following steps:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) rinsing, drying and crushing overground part of the thorn leaves, adding 75% ethanol in an amount which is 15 times that of the thorn leaves, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain the thorn leaf extract;
(6) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and lavender essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the Yunnan camellia extract, the dogliver extract, the tetrandra root extract and the thorn leaf extract into the mixture while stirring, homogenizing in a high-speed homogenizer after the addition is finished, sterilizing after the homogenization is finished, and subpackaging to obtain the whitening and freckle-removing facial cream.
Whitening and freckle removing function test
The whitening and freckle removing functions of the face creams prepared in the examples 1-2 and the comparative examples 1-2 of the invention are tested.
[ test objects and groups ]
Selecting 240 female subjects with blotchy skin, wherein the female subjects are 18-55 years old;
randomized into 5 groups of 48 cases:
(1) test 1 group: inventive cream (example 1);
(2) test 2 groups: inventive cream (example 2);
(3) control 1 group: the face cream (comparative example 1) after changing the formulation and the production method;
(4) control 2 group: the cream after changing the production method (comparative example 2);
(5) blank control group.
[ METHOD OF USE ]
The corresponding face cream is used by each test group of testees respectively 1 time in the morning and at night, after the skin is cleaned, 1g of face cream is gently massaged on the face and the spot part until the face and the spot part are completely absorbed, and the skin test is carried out after the face cream is continuously used for 30 days.
[ test indexes and test methods ]
(1) Melanin content in skin cells: the melanin content in the cells of the same facial Skin area before and after the use of the cream was measured by the Skin Surface Analyzer (SSA, CK) system, and the change value thereof was calculated.
(2) Plaque area change: the area of the whole of the yellow-brown patches on the face before and after the use of the cream was measured with a scale, and the change value thereof was calculated.
(3) Plaque color shade change: the brown color card Bn (C + M + Y) in the practical standard color card published by the mapping publishing company is used for measuring the color depth of the yellowish-brown patches in the same facial skin area before and after the facial cream is used, and the change value of the yellowish-brown patches is calculated.
[ test results ]
The test results are shown in table 1 below (taking the mean of the test indices for each group of subjects):
table 1 skin test results
The test result shows that: compared with a blank control group, the skin melanin content, the plaque area and the plaque color shade index of the test subjects in each test group are improved to different degrees. In contrast, the whitening, freckle removing and pigmentation reducing effects of the cream in the examples 1-2 of the invention are better than those of the products in the comparative examples 1-2 with changed raw material formulas or production processes.
While the preferred embodiments and examples of the present invention have been described in detail, the present invention is not limited to the embodiments and examples, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.
Claims (10)
1. A whitening and freckle-removing facial cream is prepared from the following raw materials in parts by weight:
2. the whitening and freckle-removing facial cream according to claim 1, wherein the raw materials in parts by weight are as follows:
3. the whitening and freckle-removing facial cream according to claim 1 or 2, wherein the natural plant essence is one or more selected from jasmine essential oil, rose essential oil, gardenia essential oil, sweet osmanthus essential oil, lavender essential oil and jojoba essential oil.
4. The whitening and freckle-removing facial cream according to claim 1 is prepared by the following method:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) the cream is prepared by the steps of adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and natural plants into olive oil, fully stirring to obtain a uniform mixture, then sequentially and slowly adding the green tea extract, the camellia yunnanensis extract, the cynanchum komarovii extract and the tetrandra extract into the mixture while stirring, homogenizing in a high-speed homogenizer after the addition is finished, sterilizing after the homogenization is finished, and subpackaging.
5. The whitening and freckle-removing facial cream according to claim 1, further comprising the following raw materials: 0.9-1.1 parts of thorn leaf extract.
6. The whitening and freckle-removing facial cream according to claim 5, wherein the raw materials in parts by weight are as follows:
7. the cream with whitening and freckle removal functions of claim 6, which is prepared by the following method:
(1) rinsing, drying and crushing green tea, adding 15% ethanol in an amount which is 20 times that of the green tea, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a green tea extract;
(2) rinsing, drying and crushing camellia Yunnanensis, adding 10 times of 15% ethanol and 1 time of 20% baking soda solution, soaking for 1 hour, then extracting under reflux for 1 hour, filtering, repeatedly extracting filter residue for 1 time under the same condition, filtering, combining filtrates, and vacuum drying the filtrate to obtain the camellia Yunnanensis extract;
(3) rinsing herba Setariae viridis, drying, pulverizing, adding 10 times of 30% ethanol, soaking for 1 hr, reflux extracting for 1 hr, filtering, extracting the residue under the same conditions for 1 time, filtering, mixing filtrates, and vacuum drying the filtrate to obtain herba Setariae viridis extract;
(4) rinsing, drying and crushing tetrandra root, adding 15 times of 15% ethanol and 1.5 times of acetic acid, soaking for 1 hour, performing reflux extraction for 1 hour, filtering, and performing vacuum drying on the filtrate to obtain a tetrandra root extract;
(5) rinsing, drying and crushing the overground part of the thorn leaves, soaking the thorn leaves in a 60% baking soda solution for 6 hours, filtering, draining, adding a 15 times of a mixed solvent of 75% ethanol and ethyl acetate (1: 1.3), soaking for 1 hour, extracting for 1 hour under reflux, filtering, and drying the filtrate in vacuum to obtain the thorn leaf extract;
(6) adding arbutin, licoflavone, nicotinamide, hesperetin, tranexamic acid, vitamin C, gallic acid, ceramide and lavender essential oil into olive oil, fully stirring to obtain a uniform mixture, then sequentially slowly adding the green tea extract, the Yunnan camellia extract, the dogliver extract, the tetrandra root extract and the thorn leaf extract into the mixture while stirring, homogenizing in a high-speed homogenizer after the addition is finished, sterilizing after the homogenization is finished, and subpackaging to obtain the whitening and freckle-removing facial cream.
8. The cream with skin whitening and freckle removing functions of any one of claims 1 to 7, wherein the cream with skin whitening and freckle removing functions is further prepared into an emulsion or a mask with skin whitening and freckle removing functions according to a conventional method in the field.
9. Use of the whitening and spot-removing cream as claimed in any one of claims 1 to 7 in the preparation of cosmetics or skin care products.
10. The cream with whitening and freckle removal functions of claim 4 or 7, wherein the cream with whitening and freckle removal functions is placed in a high-speed homogenizer for homogenization during the preparation process, intelligent inspection needs to be carried out on the homogenate to judge whether the homogenate meets the requirements, and the specific steps of the inspection are as follows:
s1, extracting 50ML of the homogenate of the uppermost portion of said homogenate 10 times and measuring the weight of said homogenate, respectively, to save as vector X1;
s2, extracting 50ML of the homogenate of the lowermost portion of said homogenate 10 times, and measuring the weight of said homogenate, respectively, to save as vector X2;
s3, respectively calculating the stability of the vector X1 and the vector X2 by using the formula (1);
wherein,as an intermediate parameter, X1iFor the ith value of vector X1, X2iIs the ith value of vector X2, i ═ 1, 2, 3 … 10; t1 is the stability of the vector X1 obtained by calculation, t2 is the stability of the vector X2 obtained by calculation, if the value of t1 or t2 is smaller than-1.33, the homogenization stability test is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, if the test is finished, if the value is not smaller than-1.33, the step is qualified, the test is continuously carried out;
s4, performing homogeneity test by using a formula (2);
wherein QX is the result of the homogeneity test, if QX is more than or equal to 3.02, the homogeneity test is not passed, the homogenate is unqualified, the homogenate is required to be continuously put into a high-speed refiner for homogenate, the test is finished, if QX is less than 3.02, the test in the step is qualified, and the subsequent test is continued;
s5, calculating the difference degree of the vector X1 and the vector X2 by using the formula (3);
and if the CY is more than or equal to 2.16, the judgment shows that the differential degree test does not pass, the homogenate is unqualified and needs to be continuously put into a high-speed refiner for homogenate, and if the QX is less than 2.16, the judgment shows that the homogenate passes, the homogenate meets the homogenization requirement and does not need to be continuously put into the high-speed refiner for homogenate.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111996068A (en) * | 2020-07-22 | 2020-11-27 | 哈尔滨瓜上瓜农业科技有限公司 | Cucumber seed oil preparation method and cucumber seed oil cosmetic preparation method |
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| WO2018198039A8 (en) * | 2017-04-26 | 2019-12-12 | Dr. Reddy's Laboratories Limited | Topical skin care compositions |
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| CN1546000A (en) * | 2003-12-12 | 2004-11-17 | 卢藏田 | Composite white-up speckle-removing lotion |
| CN105616283A (en) * | 2015-12-30 | 2016-06-01 | 广州葆妍生物科技有限公司 | Plant-essence restorative facial cream |
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Application publication date: 20190723 |