CN1546000A - Composite white-up speckle-removing lotion - Google Patents
Composite white-up speckle-removing lotion Download PDFInfo
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- CN1546000A CN1546000A CNA200310112542XA CN200310112542A CN1546000A CN 1546000 A CN1546000 A CN 1546000A CN A200310112542X A CNA200310112542X A CN A200310112542XA CN 200310112542 A CN200310112542 A CN 200310112542A CN 1546000 A CN1546000 A CN 1546000A
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Abstract
The invention relates to a leukoplakia dispelling liquid which comprises water-soluble plant extract prepared from ginseng, dahurian angelica root, licorice root, mulberry peel, bearberry, baikal skullcap root, kojic acid, propylene glycol, hyaluronic acid, methyl ester, and propyl ester.
Description
Technical field
The present invention relates to beauty treatment fields, especially a kind of whitening and freckle-removing liquid.
Background technology
Pigmented spots are a kind of skin phenomenons that are common in female face.Why the chromogenesis speckle is because the dermal melanin distribution of particles is inhomogeneous, causes local occur speckle, the patch darker than the normal colour of skin.Exposure to Sunlight excessively, endocrine disturbance, chronic liver sausage gastric disease, cosmetics improper use etc., all may be the inducement that causes pigmented spots.Generally speaking, whitening and speckle dispelling should be multi-faceted in addition maintenance conditioning, just can reach the effect of taking stopgap measures and effecting a permanent cure.The method of whitening and speckle dispelling has a lot, as notes sun-proof, dietetic regulation etc., and more efficient methods is the nursing of whitening.In order to subtract the pigmentation that takes off on the face, the available skin care item of whitening and speckle dispelling safely and effectively carry out certain nursing of whitening to skin.To suppress the melanin manufacturing of skin, promote exfoliation, quicken melanic drainage.Whitening product has multiplely in the market, and its action principle and effect respectively have difference, and it is slower to take effect mostly, and safety is still disputable.
Summary of the invention
Based on research to various active composition effect in Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae, and the research for many years and the clinical experiment of the mechanism of action that pigmented spots are formed, the invention provides a kind of FUHE MEIBAI QUBAN YE that plant extract composition and chemical constituent are prepared from.This FUHE MEIBAI QUBAN YE can take effect fast, various pigmented spots are thoroughly disappeared, and effect is lasting.
A kind of FUHE MEIBAI QUBAN YE of the present invention, the weight ratio of raw material consists of: 8～10 parts of plant water-soluble extracts, 2～3 parts of kojic acids, 5～15 parts of propylene glycol, 0.1～0.2 part of hyaluronic acid, 0.1～0.2 part of methyl ester, 0.1～0.2 part of propyl ester, 0.1～0.2 part of antiseptic, 0.3～0.6 part of solubilizing agent, 0.3～0.6 part in essence, 70～84 parts of deionized waters, wherein, the raw material of described plant water-soluble extract is 2～3 parts of Radix Ginsengs by weight ratio, 2.5～3.5 parts of Radixs Angelicae Dahuricae, 1～2 portion of Radix Glycyrrhizae, 1.5～2.5 parts of Cortex Moris, 3～4 portions of Folium Vaccinii vitis-idaeaies, 4～5 parts of Radix Scutellariaes.
Wherein, antiseptic and solubilizing agent all are that this area is that cosmetic field is known, and for example, antiseptic can adopt the parabens that toxicity is low, bactericidal effect is good, and solubilizing agent can be adopted tween 20.
The preparation method of FUHE MEIBAI QUBAN YE of the present invention may further comprise the steps:
1. with plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl ester, the propyl ester of described weight portion, add successively in the deionized water, stir while mixing;
2. add antiseptic, solubilizing agent, essence, stir;
3. ultraviolet disinfection is 30～40 minutes, the elimination insoluble matter, and discharging was left standstill 24 hours, and packing after the assay was approved gets product.
Described plant water-soluble extract is to make according to the following steps:
1. Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae with described weight portion adds deionized water by 1: 10～20 parts, soaks, and decocts, and filters, and collects filtrate;
2. filtering residue is added deionized water by 1: 10～20 parts, soak, decoct, filter, collect filtrate;
3. filtering residue is added 95% ethanol by 1: 5～10 parts, soak, filter, collect filtrate;
4. 3., collect filtrate with the filtering residue repeating step;
5. merge 1., 2., 3., the 4. filtrate of gained.
FUHE MEIBAI QUBAN YE of the present invention is electrine liquid, appearance transparent, and abnormal smells from the patient is slight, and pH is 4.0～6.5.This product should avoid directly being subjected to sunlight or strong illumination in 15～25 ℃ of sealed storage in the exsiccant environment of darkness.This FUHE MEIBAI QUBAN YE also is applicable to series of products such as making water preparation, cream frost, emulsion, essence.
FUHE MEIBAI QUBAN YE of the present invention contains the whitening and speckle dispelling active component of several important, and to add the dynamics of havoc melanin fabrication schedule, to suppress melanin synthetic comprehensively.Detect by analysis, these whitening and speckle dispelling active component comprise: (1) kojic acid: can suppress to make the activity of the activatory tryrosinase of melanin, the oxidisability melanin of dark color is reduced into the reproducibility melanin of light color; (2) biological flavone: activity that can 100% restraint of tyrosinase, and can suppress intermediate DOPA quinone and generate melanin; (3) triterpene: suppress the division of keratinocyte and melanocyte, promote the corneocyte metabolism to peel off, make melanin accelerate to discharge outside the skin, have extremely strong spot-removing function; (4) ginsenoside: its anti-radical action is stronger, and contains polysaccharide polypeptide and various trace elements, has the metabolic effect of adjusting; (5) Folium Vaccinii vitis-idaeae extract: can skin whitening, antioxidation simultaneously; (6) Cortex Mori extract: help to whiten and strengthen the immunity of skin, have moisture-keeping functions concurrently; (7) Radix Angelicae Dahuricae extract: can skin whitening, Radix Angelicae Dahuricae.
The present invention is a kind of efficient and safe natural FUHE MEIBAI QUBAN YE, it can suppress melanic generation effectively, and can effectively decompose the melanin of skin surface, make whiteness of skin and the effect of pigmented spots or flaw of dispeling fairly obvious, make skin become bright and clean and have no time.The present invention can both give play to effective inhibition and decomposition for increasing freckle, chloasma, senile plaque and the melanin deposition etc. that cause because of Exposure to Sunlight, hormone imbalance, age, simultaneously, do not contain compositions such as hydroquinone, through on probation without any side effects, be efficient and whitening cosmetics safety.
The specific embodiment
Embodiment one:
A kind of FUHE MEIBAI QUBAN YE, the weight ratio of raw material consists of:
8 parts of plant water-soluble extracts
2 parts of kojic acids
5 parts of propylene glycol
0.1 part of hyaluronic acid
0.1 part of methyl ester
0.1 part of propyl ester
0.1 part in P-hydroxybenzoic acid sodium
0.3 part of tween 20
0.3 part in essence
84 parts of deionized waters
Wherein, P-hydroxybenzoic acid sodium is paraben preservative, and tween 20 is solubilizing agent.
Wherein, the raw material of described plant water-soluble extract is by weight ratio:
3 parts of Radix Ginsengs
3.5 parts of the Radixs Angelicae Dahuricae
2 parts in Radix Glycyrrhizae
2.5 parts of Cortex Moris
4 parts of Folium Vaccinii vitis-idaeaies
5 parts of Radix Scutellariaes
The preparation method of the described FUHE MEIBAI QUBAN YE of present embodiment may further comprise the steps:
1. plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl ester, the propyl ester of described weight portion add in the deionized water successively, stir while mixing;
2. add antiseptic, solubilizing agent, essence, stir;
3. ultraviolet disinfection is 30～40 minutes, the elimination insoluble matter, and discharging was left standstill 24 hours, and packing after the assay was approved gets product.
Described plant water-soluble extract is to make according to the following steps:
1. Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae with described weight portion adds deionized water by 1: 10 part, soaks, and decocts, and filters, and collects filtrate;
2. filtering residue is added deionized water by 1: 10 part, soak, decoct, filter, collect filtrate;
3. filtering residue is added 95% ethanol by 1: 5 part, soak, filter, collect filtrate;
4. 3., collect filtrate with the filtering residue repeating step;
5. merge 1., 2., 3., the 4. filtrate of gained.
Embodiment two:
A kind of FUHE MEIBAI QUBAN YE, the weight ratio of raw material consists of:
8 parts of plant water-soluble extracts
3 parts of kojic acids
15 parts of propylene glycol
0.2 part of hyaluronic acid
0.2 part of methyl ester
0.2 part of propyl ester
0.2 part in P-hydroxybenzoic acid sodium
0.6 part of tween 20
0.6 part in essence
72 parts of deionized waters
Wherein, P-hydroxybenzoic acid sodium is paraben preservative, and tween 20 is solubilizing agent.
Wherein, the raw material of described plant water-soluble extract is by weight ratio:
2 parts of Radix Ginsengs
2.5 parts of the Radixs Angelicae Dahuricae
1 part in Radix Glycyrrhizae
1.5 parts of Cortex Moris
3 parts of Folium Vaccinii vitis-idaeaies
4 parts of Radix Scutellariaes
The preparation method of the described FUHE MEIBAI QUBAN YE of present embodiment is identical with embodiment one.
Embodiment three:
A kind of FUHE MEIBAI QUBAN YE, the weight ratio of raw material consists of:
10 parts of plant water-soluble extracts
2 parts of kojic acids
5 parts of propylene glycol
0.1 part of hyaluronic acid
0.1 part of methyl ester
0.1 part of propyl ester
0.1 part in P-hydroxybenzoic acid sodium
0.3 part of tween 20
0.3 part in essence
82 parts of deionized waters
Wherein, P-hydroxybenzoic acid sodium is paraben preservative, and tween 20 is solubilizing agent.
Wherein, the raw material of described plant water-soluble extract is by weight ratio:
2 parts of Radix Ginsengs
2.5 parts of the Radixs Angelicae Dahuricae
1 part in Radix Glycyrrhizae
1.5 parts of Cortex Moris
3 parts of Folium Vaccinii vitis-idaeaies
4 parts of Radix Scutellariaes
The preparation method of the described FUHE MEIBAI QUBAN YE of present embodiment may further comprise the steps:
1. plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl ester, the propyl ester of described weight portion add in the deionized water successively, stir while mixing;
2. add antiseptic, solubilizing agent, essence, stir;
3. ultraviolet disinfection is 30～40 minutes, the elimination insoluble matter, and discharging was left standstill 24 hours, and packing after the assay was approved gets product.
Described plant water-soluble extract is to make according to the following steps:
1. Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae with described weight portion adds deionized water by 1: 10 part, soaks, and decocts, and filters, and collects filtrate;
2. filtering residue is added deionized water by 1: 20 part, soak, decoct, filter, collect filtrate;
3. filtering residue is added 95% ethanol by 1: 10 part, soak, filter, collect filtrate;
4. 3., collect filtrate with the filtering residue repeating step;
5. merge 1., 2., 3., the 4. filtrate of gained.
Embodiment four:
A kind of FUHE MEIBAI QUBAN YE, the weight ratio of raw material consists of:
10 parts of plant water-soluble extracts
3 parts of kojic acids
15 parts of propylene glycol
0.2 part of hyaluronic acid
0.2 part of methyl ester
0.2 part of propyl ester
0.2 part in P-hydroxybenzoic acid sodium
0.6 part of tween 20
0.6 part in essence
70 parts of deionized waters
Wherein, P-hydroxybenzoic acid sodium is paraben preservative, and tween 20 is solubilizing agent.
Wherein, the raw material of described plant water-soluble extract is by weight ratio:
3 parts of Radix Ginsengs
3.5 parts of the Radixs Angelicae Dahuricae
2 parts in Radix Glycyrrhizae
2.5 parts of Cortex Moris
4 parts of Folium Vaccinii vitis-idaeaies
5 parts of Radix Scutellariaes
The preparation method of the described FUHE MEIBAI QUBAN YE of present embodiment is identical with embodiment three.
Embodiment five:
A kind of FUHE MEIBAI QUBAN YE, the weight ratio of raw material consists of:
9 parts of plant water-soluble extracts
2.5 parts of kojic acids
10 parts of propylene glycol
0.15 part of hyaluronic acid
0.15 part of methyl ester
0.15 part of propyl ester
0.15 part in P-hydroxybenzoic acid sodium
0.5 part of tween 20
0.4 part in essence
77 parts of deionized waters
Wherein, P-hydroxybenzoic acid sodium is paraben preservative, and tween 20 is solubilizing agent.
Wherein, the raw material of described plant water-soluble extract is by weight ratio:
2.5 parts of Radix Ginsengs
3.0 parts of the Radixs Angelicae Dahuricae
1.5 parts in Radix Glycyrrhizae
2.0 parts of Cortex Moris
3.5 parts of Folium Vaccinii vitis-idaeaies
4.5 parts of Radix Scutellariaes
The preparation method of the described FUHE MEIBAI QUBAN YE of present embodiment may further comprise the steps:
1. plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl ester, the propyl ester of described weight portion add in the deionized water successively, stir while mixing;
2. add antiseptic, solubilizing agent, essence, stir;
3. ultraviolet disinfection is 30～40 minutes, the elimination insoluble matter, and discharging was left standstill 24 hours, and packing after the assay was approved gets product.
Described plant water-soluble extract is to make according to the following steps:
1. Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae with described weight portion adds deionized water by 1: 15 part, soaks, and decocts, and filters, and collects filtrate;
2. filtering residue is added deionized water by 1: 15 part, soak, decoct, filter, collect filtrate;
3. filtering residue is added 95% ethanol by 1: 8 part, soak, filter, collect filtrate;
4. 3., collect filtrate with the filtering residue repeating step;
5. merge 1., 2., 3., the 4. filtrate of gained.
Embodiment six:
The control experiment of FUHE MEIBAI QUBAN YE of the present invention:
Object of study:
The trier is divided into 6 and organizes greatly, and its principal character is:
(1) passeris montani saturati speckle; (2) acne, acne, blackhead; (4) chloasma; (3) withered and yellow black face; (4) chloasma; (5) sun speckle.Every big group is divided into two experiment groups again, each 50 people of every group, wherein male 10 people, women 40 people.
Experimental technique:
Common cosmetics on the group one usefulness market, used 30 continuously at every day 1 time.
The group dual-purpose embodiment of the invention five described FUHE MEIBAI QUBAN YE, were used 30 continuously at every day 1 time.
Experimental result:
| Transference cure | Symptom obviously alleviates | Remission | Symptom does not have improvement | Severity of symptoms | ||
| Big group one | Group 1 | ?2 | ?5 | ?7 | ?36 | ?0 |
| Group 2 | ?25 | ?18 | ?7 | ?0 | ?0 | |
| Big group two | Group 1 | ?1 | ?6 | ?3 | ?40 | ?0 |
| Group 2 | ?30 | ?20 | ?0 | ?0 | ?0 | |
| Big group three | Group 1 | ?3 | ?4 | ?9 | ?34 | ?0 |
| Group 2 | ?27 | ?15 | ?8 | ?0 | ?0 | |
| Big group four | Group 1 | ?4 | ?3 | ?5 | ?38 | ?0 |
| Group 2 | ?28 | ?17 | ?5 | ?0 | ?0 | |
| Big group five | Group 1 | ?3 | ?7 | ?2 | ?38 | ?0 |
| Group 2 | ?29 | ?18 | ?3 | ?0 | ?0 | |
| Big group six | Group 1 | ?5 | ?3 | ?6 | ?36 | ?0 |
| Group 2 | ?26 | ?20 | ?4 | ?0 | ?0 | |
The result shows:
(1) product of the present invention has good effect for symptoms such as freckle, acne, acne, blackhead, chloasma, withered and yellow black face, chloasma, sun speckles, compares the improvement that all has in various degree with general cosmetics.
(2) product of the present invention in use, but just onset on the 20th, 30 days effect is fairly obvious.
Find also in the experiment that (3) product of the present invention also has 80% desalination effect to black eye, eye pouch, birthmark, senile plaque, wrinkle etc.
Claims (3)
1, a kind of FUHE MEIBAI QUBAN YE, it is characterized in that, the weight ratio of raw material consists of: 8～10 parts of plant water-soluble extracts, 2～3 parts of kojic acids, 5～15 parts of propylene glycol, 0.1～0.2 part of hyaluronic acid, 0.1～0.2 part of methyl ester, 0.1～0.2 part of propyl ester, 0.1～0.2 part of antiseptic, 0.3～0.6 part of solubilizing agent, 0.3～0.6 part in essence, 70～84 parts of deionized waters, wherein, the raw material of described plant water-soluble extract is 2～3 parts of Radix Ginsengs by weight ratio, 2.5～3.5 parts of Radixs Angelicae Dahuricae, 1～2 portion of Radix Glycyrrhizae, 1.5～2.5 parts of Cortex Moris, 3～4 portions of Folium Vaccinii vitis-idaeaies, 4～5 parts of Radix Scutellariaes.
2, the preparation method of FUHE MEIBAI QUBAN YE as claimed in claim 1 is characterized in that, may further comprise the steps:
1. with plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl ester, the propyl ester of described weight portion, add successively in the deionized water, stir while mixing;
2. add antiseptic, solubilizing agent, essence, stir;
3. ultraviolet disinfection is 30～40 minutes, the elimination insoluble matter, and discharging was left standstill 24 hours, and packing after the assay was approved gets product.
3, FUHE MEIBAI QUBAN YE according to claim 1 is characterized in that, described plant water-soluble extract is to make according to the following steps:
1. Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, the Radix Scutellariae with described weight portion adds deionized water by 1: 10～20 parts, soaks, and decocts, and filters, and collects filtrate;
2. filtering residue is added deionized water by 1: 10～20 parts, soak, decoct, filter, collect filtrate;
3. filtering residue is added 95% ethanol by 1: 5～10 parts, soak, filter, collect filtrate;
4. 3., collect filtrate with the filtering residue repeating step;
5. merge 1., 2., 3., the 4. filtrate of gained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200310112542XA CN1546000A (en) | 2003-12-12 | 2003-12-12 | Composite white-up speckle-removing lotion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200310112542XA CN1546000A (en) | 2003-12-12 | 2003-12-12 | Composite white-up speckle-removing lotion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1546000A true CN1546000A (en) | 2004-11-17 |
Family
ID=34336566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA200310112542XA Pending CN1546000A (en) | 2003-12-12 | 2003-12-12 | Composite white-up speckle-removing lotion |
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| Country | Link |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102525853A (en) * | 2011-12-23 | 2012-07-04 | 广州市娇兰化妆品有限公司 | Compound natural plant extract with spot-removing function and preparation method and application thereof |
| CN102908411A (en) * | 2012-11-21 | 2013-02-06 | 安文娟 | Ointment for treating acne |
| CN103830152A (en) * | 2014-03-14 | 2014-06-04 | 集安五味堂生物科技有限公司 | Cosmetic composition and essence with skin whitening function |
| CN110037962A (en) * | 2019-05-27 | 2019-07-23 | 贝德氏（上海）健康科技股份有限公司 | A kind of face cream of whitening spot-removing |
-
2003
- 2003-12-12 CN CNA200310112542XA patent/CN1546000A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102525853A (en) * | 2011-12-23 | 2012-07-04 | 广州市娇兰化妆品有限公司 | Compound natural plant extract with spot-removing function and preparation method and application thereof |
| CN102525853B (en) * | 2011-12-23 | 2013-06-05 | 广州市娇兰化妆品有限公司 | Compound natural plant extract with spot-removing function and preparation method and application thereof |
| CN102908411A (en) * | 2012-11-21 | 2013-02-06 | 安文娟 | Ointment for treating acne |
| CN103830152A (en) * | 2014-03-14 | 2014-06-04 | 集安五味堂生物科技有限公司 | Cosmetic composition and essence with skin whitening function |
| CN103830152B (en) * | 2014-03-14 | 2015-10-28 | 集安五味堂生物科技有限公司 | There is cosmetic composition and the essence of whitening function |
| CN110037962A (en) * | 2019-05-27 | 2019-07-23 | 贝德氏（上海）健康科技股份有限公司 | A kind of face cream of whitening spot-removing |
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