CN1100266C - 虫荧光素酶标记方法和标记的产物 - Google Patents

虫荧光素酶标记方法和标记的产物 Download PDF

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Publication number
CN1100266C
CN1100266C CN95195776A CN95195776A CN1100266C CN 1100266 C CN1100266 C CN 1100266C CN 95195776 A CN95195776 A CN 95195776A CN 95195776 A CN95195776 A CN 95195776A CN 1100266 C CN1100266 C CN 1100266C
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CN
China
Prior art keywords
luciferase
antibody
adenosine triphosphate
luciferin
nucleic acid
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Expired - Fee Related
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CN95195776A
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English (en)
Chinese (zh)
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CN1161746A (zh
Inventor
D·斯奎勒尔
M·J·墨菲
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3 M Inneva Ltd
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UK Secretary of State for Defence
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Publication of CN1161746A publication Critical patent/CN1161746A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Labeling Devices (AREA)
CN95195776A 1994-09-01 1995-08-30 虫荧光素酶标记方法和标记的产物 Expired - Fee Related CN1100266C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9417593.2 1994-09-01
GB9417593A GB9417593D0 (en) 1994-09-01 1994-09-01 Luciferase labelling method

Publications (2)

Publication Number Publication Date
CN1161746A CN1161746A (zh) 1997-10-08
CN1100266C true CN1100266C (zh) 2003-01-29

Family

ID=10760673

Family Applications (1)

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CN95195776A Expired - Fee Related CN1100266C (zh) 1994-09-01 1995-08-30 虫荧光素酶标记方法和标记的产物

Country Status (13)

Country Link
US (1) US5837465A (enExample)
EP (1) EP0778945B1 (enExample)
JP (1) JP3594609B2 (enExample)
CN (1) CN1100266C (enExample)
AU (1) AU697586B2 (enExample)
BR (1) BR9508652A (enExample)
DE (1) DE69523060T2 (enExample)
GB (1) GB9417593D0 (enExample)
IN (1) IN183949B (enExample)
MX (1) MX9701479A (enExample)
RU (1) RU2199125C2 (enExample)
WO (1) WO1996007100A2 (enExample)
ZA (1) ZA957373B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171802B1 (en) * 1998-06-10 2001-01-09 Kent State University Detection and amplification of ligands
US20040214227A1 (en) * 1999-12-22 2004-10-28 Erik Joly Bioluminescence resonance energy transfer (bret) fusion molecule and method of use
KR100414637B1 (ko) * 2000-02-08 2004-01-13 (주)에스제이바이오메드 사람 미토콘드리아 아데닐레이트 키나제 이소자임들에대한 항체와 면역학적 제제 및 심장질환 진단키트
US7109315B2 (en) 2000-03-15 2006-09-19 Bruce J. Bryan Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
DE10137342A1 (de) * 2001-07-31 2003-03-06 Infineon Technologies Ag Biosensor und Verfahren zum Erfassen von makromolekularen Biopolymeren mittels mindestens einer Einheit zum Immobilisieren von makromolekularen Biopolymeren
US20050037355A1 (en) * 2001-11-14 2005-02-17 Day John Cavendish Signal system and elements used therein
FR2840687B1 (fr) * 2002-06-05 2008-01-25 Bio Merieux Procede de detection simultanee de reactions d'hybridation et immunologiques et ses utilisations en diagnostic
AU2003288474A1 (en) * 2002-06-24 2004-03-19 Exiqon A/S Methods and systems for detection and isolation of a nucleotide sequence
US7996825B2 (en) * 2003-10-31 2011-08-09 Hewlett-Packard Development Company, L.P. Cross-file inlining by using summaries and global worklist
US8329397B2 (en) * 2005-06-03 2012-12-11 Beacon Biotechnology Inc. Chemiluminescence proximity nucleic acid assay
US20070254311A1 (en) * 2006-04-26 2007-11-01 Cardiogenics Inc. Covalent modification and conjugation of luciferase
JP4604187B2 (ja) * 2007-08-14 2010-12-22 独立行政法人産業技術総合研究所 糖鎖を介したルシフェラーゼと有機蛍光色素間のエネルギー移動を利用した可視−近赤外光プローブ
US8183007B2 (en) * 2008-07-22 2012-05-22 Promega Corporation ADP detection based methods using adenylate cyclase and bioluminescence
EP2635583B1 (en) 2010-11-02 2015-06-03 Promega Corporation Coelenterazine derivatives and methods of using same
AU2011323418B2 (en) 2010-11-02 2017-07-27 Promega Corporation Novel coelenterazine substrates and methods of use
US10519483B2 (en) 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
MX382157B (es) 2012-02-21 2025-03-13 Laboratory Corp America Holdings Metodos y sistemas para deteccion de microorganismos.
JP2016509835A (ja) 2013-02-22 2016-04-04 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ ルシフェラーゼ及びヌクレオシドホスフェートの発光検出のための安定化された配合物
US9927430B2 (en) 2014-01-29 2018-03-27 Promega Corporation Pro-substrates for live cell applications
JP6703484B2 (ja) 2014-01-29 2020-06-03 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 細胞による取り込み測定のための、標識用試薬としての、キノンでマスクされたプローブ
JP6510041B2 (ja) 2014-10-08 2019-05-08 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 生物発光サクシネート検出アッセイ
CN109957607A (zh) * 2017-12-14 2019-07-02 深圳先进技术研究院 一种检测探针及其应用
JP2022536960A (ja) 2019-06-21 2022-08-22 ラボラトリー コーポレイション オブ アメリカ ホールディングス Ｌｉｓｔｅｒｉａの検出のための変異体バクテリオファージを生成するための方法
RU2744869C2 (ru) * 2019-08-08 2021-03-16 Общество с ограниченной ответственностью "ПЛАНТА" Метод и реактивы для детекции активности люциферазы
JP7781741B2 (ja) 2019-08-26 2025-12-08 ラボラトリー コーポレイション オブ アメリカ ホールディングス 組換え繁殖欠損指標バクテリオファージを使用して微生物を検出するためのデバイスおよび方法
US11591633B2 (en) 2019-09-11 2023-02-28 Laboratory Corporation Of America Holdings Methods and systems for the rapid detection of bacteria using recombinant bacteriophage to express an indicator subunit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583024A (en) * 1985-12-02 1996-12-10 The Regents Of The University Of California Recombinant expression of Coleoptera luciferase

Also Published As

Publication number Publication date
JPH10504903A (ja) 1998-05-12
GB9417593D0 (en) 1994-10-19
WO1996007100A3 (en) 1996-05-02
JP3594609B2 (ja) 2004-12-02
RU2199125C2 (ru) 2003-02-20
ZA957373B (en) 1996-05-20
IN183949B (enExample) 2000-05-20
DE69523060D1 (de) 2001-11-08
AU697586B2 (en) 1998-10-08
MX9701479A (es) 1998-02-28
EP0778945B1 (en) 2001-10-04
BR9508652A (pt) 1997-11-25
US5837465A (en) 1998-11-17
DE69523060T2 (de) 2002-06-20
AU3352595A (en) 1996-03-22
CN1161746A (zh) 1997-10-08
WO1996007100A2 (en) 1996-03-07
EP0778945A2 (en) 1997-06-18

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Owner name: 3M INNOVATION CO., LTD.

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Effective date: 20080425

C41 Transfer of patent application or patent right or utility model
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Address after: Minnesota, USA

Patentee after: 3 M Inneva Ltd.

Address before: Wiltshire

Patentee before: British Ministry of Defence

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20030129

Termination date: 20100830