CN109985056A - 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物 - Google Patents

用于在治疗皮肤病中局部使用的烟酰胺核苷组合物 Download PDF

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Publication number
CN109985056A
CN109985056A CN201910027571.7A CN201910027571A CN109985056A CN 109985056 A CN109985056 A CN 109985056A CN 201910027571 A CN201910027571 A CN 201910027571A CN 109985056 A CN109985056 A CN 109985056A
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China
Prior art keywords
skin
nicotinamide riboside
salt
cells
composition
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Pending
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CN201910027571.7A
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English (en)
Chinese (zh)
Inventor
安·德仁-路易斯
特洛伊·鲁尼穆斯
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Chromadex Inc
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Chromadex Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Birds (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
CN201910027571.7A 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物 Pending CN109985056A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361897713P 2013-10-30 2013-10-30
US61/897,713 2013-10-30
CN201480071722.4A CN105873937A (zh) 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物

Related Parent Applications (1)

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CN201480071722.4A Division CN105873937A (zh) 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物

Publications (1)

Publication Number Publication Date
CN109985056A true CN109985056A (zh) 2019-07-09

Family

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CN201910027571.7A Pending CN109985056A (zh) 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物
CN201480071722.4A Pending CN105873937A (zh) 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201480071722.4A Pending CN105873937A (zh) 2013-10-30 2014-10-30 用于在治疗皮肤病中局部使用的烟酰胺核苷组合物

Country Status (12)

Country Link
US (2) US10688118B2 (cg-RX-API-DMAC7.html)
EP (1) EP3063163B1 (cg-RX-API-DMAC7.html)
JP (1) JP6509844B2 (cg-RX-API-DMAC7.html)
KR (3) KR20160067195A (cg-RX-API-DMAC7.html)
CN (2) CN109985056A (cg-RX-API-DMAC7.html)
AU (1) AU2014342185B2 (cg-RX-API-DMAC7.html)
CA (1) CA2928656C (cg-RX-API-DMAC7.html)
ES (1) ES2925879T3 (cg-RX-API-DMAC7.html)
MX (2) MX385305B (cg-RX-API-DMAC7.html)
NZ (1) NZ719328A (cg-RX-API-DMAC7.html)
WO (1) WO2015066382A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201603314B (cg-RX-API-DMAC7.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638827A (zh) * 2019-10-17 2020-01-03 泓博元生命科技(深圳)有限公司 Nadh及其盐在制备皮肤色素抑制剂中的应用
CN111166760A (zh) * 2019-12-17 2020-05-19 浙江安赛新材料科技有限公司 β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用
CN111184732A (zh) * 2020-03-04 2020-05-22 武汉华纳联合药业有限公司 一种复合组合物制剂及其制备方法和皮肤炎症中的应用

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RU2016149767A (ru) 2014-06-06 2018-07-16 Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед Аналоги никотинамидрибозида и фармацевтические композиции и их применение
CA2956163C (en) 2014-07-24 2023-01-10 W.R. Grace & Co.-Conn. Crystalline form of nicotinamide riboside
ES2963057T3 (es) 2015-03-09 2024-03-25 Grace W R & Co Forma cristalina de ribósido de nicotinamida
NZ735411A (en) * 2015-03-16 2021-07-30 Chromadex Inc Nicotinic acid riboside or nicotinamide riboside compositions, reduced derivatives thereof, and the use thereof
WO2016178945A1 (en) 2015-05-01 2016-11-10 The Procter & Gamble Company Method of improving the appearance of skin and compositions therefor using nicotinamide riboside
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JP6611099B2 (ja) * 2015-05-01 2019-11-27 ザ プロクター アンド ギャンブル カンパニー 皮膚の健康を改善する方法及びそのための組成物
CN107849083A (zh) * 2015-06-10 2018-03-27 益力舒健康公司 用于治疗皮肤病症的烟酰胺核苷和紫檀芪组合物和方法
US20180177703A1 (en) * 2015-06-25 2018-06-28 N.V. Perricone Llc Niacinamide Mononucleotide Formulations For Skin Aging
US20160374908A1 (en) 2015-06-29 2016-12-29 The Procter & Gamble Company Skin care composition and methods of using the same
WO2017004102A1 (en) 2015-06-29 2017-01-05 The Procter & Gamble Company Multi-component skin care product comprising nicoinamide riboside in a multi-chambered container
WO2017004100A1 (en) 2015-06-29 2017-01-05 The Procter & Gamble Company Encapsulated particles comprising nicotinamide riboside
KR102114892B1 (ko) 2016-01-11 2020-05-26 더 프록터 앤드 갬블 캄파니 피부 상태의 치료 방법 및 그를 위한 조성물
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ES2948968T3 (es) 2016-04-20 2023-09-22 Chromadex Inc Uso del ribósido de ácido nicotínico o derivados del ribósido de nicotinamida, y derivados reducidos de los mismos, como precursores que aumentan el NAD++
JP7132907B2 (ja) * 2016-08-22 2022-09-07 エリジウム・ヘルス・インコーポレイテッド ニコチンアミドリボシド及びプテロスチルベン組成物及び神経変性障害の治療方法
NZ803738A (en) 2016-11-11 2024-05-31 Chromadex Inc Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof
US11071747B2 (en) 2016-11-29 2021-07-27 University Of Iowa Research Foundation Use of NAD precursors for breast enhancement
EP3554285A4 (en) 2016-11-29 2021-01-20 University of Iowa Research Foundation USE OF NAD PRECURSORS TO IMPROVE THE HEALTH OF MOTHER AND / OR OFFspring
JP7082623B2 (ja) 2016-12-21 2022-06-08 ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ シスチンを有するパーソナルケア用組成物
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EA201991003A1 (ru) 2016-12-21 2019-12-30 Юнилевер Н.В. Композиции для личной гигиены, содержащие малорастворимые соединения
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EP3624808A4 (en) * 2017-05-18 2021-03-03 Elysium Health, Inc. PROCEDURES AND COMPOSITIONS FOR IMPROVED SLEEP
US11286274B2 (en) 2017-06-19 2022-03-29 Mitopower Llc Nicotinamide riboside derivatives and their uses
EP3641725A1 (en) 2017-06-23 2020-04-29 The Procter and Gamble Company Composition and method for improving the appearance of skin
CA3108015A1 (en) 2017-07-28 2019-01-31 Centers For Age Control, Inc. Compositions and methods for preventing and reversing aspects of aging
JP7210459B2 (ja) * 2017-09-14 2023-01-23 めぐみ 田中 老化防止剤及び老化防止方法
GB201716391D0 (en) * 2017-10-06 2017-11-22 Xobaderm Ltd Kit for delivery of an active compound into a biological barrier
EP3727400A4 (en) 2017-12-22 2021-10-20 Elysium Health, Inc. CRYSTALLINE FORMS OF NICOTINAMIDE RIBOSIDE CHLORIDE
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition
JP6887025B2 (ja) * 2018-08-17 2021-06-16 邦泰生物工程(深▲セン▼)有限公司 安定型ニコチンアミドリボシド組成物及びその調製方法
KR102060374B1 (ko) * 2018-12-14 2019-12-30 주식회사 휴메딕스 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체
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Cited By (4)

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CN110638827A (zh) * 2019-10-17 2020-01-03 泓博元生命科技(深圳)有限公司 Nadh及其盐在制备皮肤色素抑制剂中的应用
CN111166760A (zh) * 2019-12-17 2020-05-19 浙江安赛新材料科技有限公司 β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用
CN111184732A (zh) * 2020-03-04 2020-05-22 武汉华纳联合药业有限公司 一种复合组合物制剂及其制备方法和皮肤炎症中的应用
CN111184732B (zh) * 2020-03-04 2023-09-08 武汉华纳联合药业有限公司 一种复合组合物制剂及其制备方法和皮肤炎症中的应用

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US20160250241A1 (en) 2016-09-01
MX385305B (es) 2025-03-18
JP2016538271A (ja) 2016-12-08
CA2928656C (en) 2020-07-28
KR20220098049A (ko) 2022-07-08
CN105873937A (zh) 2016-08-17
ZA201603314B (en) 2017-09-27
EP3063163A4 (en) 2017-05-10
KR20160067195A (ko) 2016-06-13
EP3063163A1 (en) 2016-09-07
KR20210107895A (ko) 2021-09-01
MX2016005574A (es) 2016-12-09
JP6509844B2 (ja) 2019-05-08
MX394291B (es) 2025-03-24
US11033568B2 (en) 2021-06-15
AU2014342185B2 (en) 2019-01-03
EP3063163B1 (en) 2022-08-10
US10688118B2 (en) 2020-06-23
WO2015066382A1 (en) 2015-05-07
ES2925879T3 (es) 2022-10-20
US20200289536A1 (en) 2020-09-17
NZ719328A (en) 2022-04-29
MX2021009652A (es) 2022-07-26
CA2928656A1 (en) 2015-05-07

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