CN109833221B

CN109833221B - Anti-aging skin care emulsion for eyes and preparation method thereof

Info

Publication number: CN109833221B
Application number: CN201910255661.1A
Authority: CN
Inventors: 吴成亮; 高先亭
Original assignee: Hefei Kadier Biotechnology Co ltd
Current assignee: Hefei Kadier Biotechnology Co ltd
Priority date: 2019-04-01
Filing date: 2019-04-01
Publication date: 2022-03-29
Anticipated expiration: 2039-04-01
Also published as: CN109833221A

Abstract

The invention discloses an anti-aging skin care emulsion for eyes, which comprises the following raw materials in percentage by mass: cosmetic polypeptide compound, polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax ester, cetyl alcohol, squalane 3-8%, isononyl isononanoate, cyclomethicone, dimethicone, shea butter, etc. Compared with the prior art, the skin care emulsion can effectively aim at target spot of pouch formation reason, promotes the formation of dermal matrix components of skin such as collagen and the like by promoting cell differentiation and collagen synthesis, improves the elasticity of the skin, and can promote the regeneration of the skin around the eyes, thereby effectively removing melanin around the eyes, eliminating the pouches, quickly removing the skin problem around the eyes and enabling the eyes to be glorious.

Description

Anti-aging skin care emulsion for eyes and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, in particular to an anti-aging skin care emulsion for eyes and a preparation method thereof.

Background

The skin is an important organ responsible for various physiological functions such as barrier function for protecting the human body from the external environment and preventing the outflow of internal moisture and useful components, thermoregulation, excretion, and the like. In general, skin is easily wrinkled compared to other organs because the skin has many opportunities to be exposed to various external stimuli. Among them, facial skin is directly exposed to sunlight, dry environment, pollutants, etc., and thus, aging phenomena such as wrinkles occur earlier than skin that is not exposed to the outside. The most typical change caused by aging of skin tissue is a change of a skin matrix (matrix), in which human skin fibroblasts (human skin fibroblasts) in the dermis layer are aged, the ability to produce fibers and matrix is reduced, and the amount of matrix is reduced as a whole, the thickness of the skin is thinned, the skin elasticity is reduced, and wrinkles are formed. That is, as aging progresses, the decrease in elasticity of the skin, the blood circulation disorder, the weakening of the skin barrier, and the like become more serious. The eye skin is the weakest part of the face, where the skin is most prone to aging and should be protected more intensively.

Currently, most representative anti-aging cosmetics for eyes mainly use functional raw materials such as Retinoids (Retinoids), vitamin C, and the like. Among retinoids, Retinoic acid (Retinoic acid) is used as a potent anti-aging therapeutic agent, but has strong irritation to the skin, and thus is limitedly used as a therapeutic agent, and retinol, retinol palmitate, and the like, which have relatively little irritation, are widely used as cosmetic materials. However, retinol and retinol palmitate are denatured by light when irradiated with light, and thus have problems with phototoxicity which causes irritation to the skin and stability thereof, and although vitamin C is also a widely used therapeutic agent for wrinkle improvement, vitamin C has disadvantages of inducing skin irritation due to strong acidity and having low stability of the substance itself. Therefore, there is an urgent need to develop a novel eye anti-aging skin care emulsion that is safe and efficient for living bodies, compared to the existing anti-aging eye skin care emulsions.

Disclosure of Invention

Aiming at the problems that the traditional anti-aging skin care emulsion for eyes is mainly focused on the aspects of oxidation resistance, moisture retention and the like and can not solve the problems of under-eye puffiness, dark under-eye circles and fine wrinkles which cause the aging of eyes, the invention provides the anti-aging skin care emulsion for eyes and the preparation method thereof, wherein the anti-aging skin care emulsion for eyes has comprehensive effects of moisture retention, wrinkle resistance, under-eye puffiness elimination and the like by taking the cosmetic peptide as the main component and aiming at the problems of wrinkle resistance and aging of eyes.

The invention is realized by adopting the following technical scheme:

the invention provides an anti-aging skin care emulsion for eyes, which comprises the following raw materials in percentage by mass: 4% of acetyl tetrapeptide-5, 4% of palmitoyl tripeptide-38, 4% of palmitoyl pentapeptide-4, 4% of carnosine, 4% of acetyl hexapeptide-8, 4% of snake venom-like peptide, 0.5% of polyglycerol-6 distearate, 0.5% of jojoba lipids, 0.5% of polyglycerol-3 beeswax, 0.5% of cetyl alcohol, 3% of squalane, 3% of isononyl isononanoate, 3% of cyclopolydimethylsiloxane, 5% of polydimethylsiloxane, 1% of shea butter, 4% of aesculus chinensis, 0.5% of xanthan gum, 1% of sodium hyaluronate, 5% of methyl propylene glycol, 1, 3-propylene glycol 5%, betaine 2%, 0.2% of p-hydroxyacetophenone, 1% of butanediol, 1% of astragalus membranaceus root extract, 1% of saposhnikovia root extract, 1% of calendula flower extract, 1% of albizia flower extract, 1% of gastrodia root extract, Dipotassium glycyrrhizinate 0.5%, caprylic/capric triglyceride 0.5%, 1, 2-pentanediol 2%, phenethylresorcinol 0.2%, bisabolol 0.5%, butyl methoxydibenzoylmethane 0.5%, 1-methylhydantoin-2-imide 0.5%, creatine 0.5%. The beautifying polypeptide compound can improve the elasticity of skin by promoting cell differentiation and collagen synthesis, and can promote the regeneration of skin around eyes, thereby preventing and reducing the generation of wrinkles on eyes, effectively removing melanin around eyes, eliminating pouches and enabling eyes to change color.

Wherein, the aesculus can clear away heat and toxic material, relieve pain and reduce swelling, and can treat skin herpes, jaundice, skin damage and the like; according to the invention, the traditional Chinese medicine component of the aesculus hippocastanum is added into the skin care product for the first time, so that the regeneration of skin around eyes can be promoted to a certain extent, eye swelling is eliminated, and black eye circles are improved.

Acetyl tetrapeptide-5: the colleagues preventing glycosylation can also influence the permeability of blood vessels, reduce the penetration of liquid in the blood vessels to periocular tissues (the main reason for the retention of liquid around the eyes), and reduce the formation of eye bags;

palmitoyl tripeptide-38: promoting the synthesis of six main components comprising collagen I, III, IV, fibronectin, hyaluronic acid, laminin 5 and the like, which form a skin matrix and an epidermal-dermal junction (DEJ);

palmitoyl pentapeptide-4: the collagen protein is an accurate simulation of a hydrolysate, namely matrikins, of a procollagen alpha 1 chain, and promotes the generation of collagen I and III and fibronectin, so that the skin thickness is increased and fine wrinkles are reduced;

acetyl hexapeptide-8: oligopeptides capable of mimicking the N-terminus of the SNAP-25 protein, which competitively inhibit the formation of the SNARE complex with SNAP-25, reduce neurotransmitter release, and prevent muscle contraction, thereby preventing wrinkle formation;

a snake venom-like peptide: simulating the action mechanism of a venom polypeptide component-waglerin 1 of the Weishi rhodostomin, reducing the contraction of muscle cells, and rapidly and reversibly eliminating simulated wrinkles, particularly expression wrinkles;

carnosine: has strong antioxidant and anti-glycosylation capability, can eliminate reactive oxygen free radicals ROS and alpha-beta unsaturated aldehyde generated in the oxidative stress process, and reduce the formation of glycosylation end products (AGEs).

The invention also provides a preparation method of the anti-aging skin care emulsion for eyes, which comprises the following steps:

(1) adding polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax, cetyl alcohol, squalane, isononyl isononanoate, cyclomethicone, dimethicone and shea butter into an oil phase pot according to the mass ratio, heating to 85 ℃, and stirring until completely dissolving to obtain a first pre-prepared solution;

(2) adding water into a water phase pot, adding xanthan gum, sodium hyaluronate, methyl propylene glycol and 3-8% of 1, 3-propylene glycol while stirring until the xanthan gum, the sodium hyaluronate, the methyl propylene glycol and the 1, 3-propylene glycol are completely dissolved to obtain a second pre-prepared solution;

(3) adding acetyl tetrapeptide-5, palmitoyl tripeptide-38, palmitoyl pentapeptide-4, carnosine, acetyl hexapeptide-8 and snake venom-like peptide into water, mixing, and stirring to obtain a third pre-prepared solution;

(4) grinding the aesculus chinensis into powder, adding 60 mass percent of ethanol solution which is 5 times of the total weight of the mixture, leaching with ethanol to obtain a leaching solution, filtering the leaching solution to remove filter residues, and heating and concentrating to obtain a fourth pre-prepared solution;

(5) pumping the pre-prepared liquid II into an emulsifying pot, slowly pumping the pre-prepared liquid I in the stirring process, homogenizing for 5min, then adding p-hydroxyacetophenone when cooling to 60 ℃ while stirring, continuously stirring and cooling to 40 ℃, adding betaine, butanediol, a skin conditioner, dimethyl glycyrrhizinate, caprylic/capric triglyceride, 1, 2-pentanediol, phenethylresorcinol, bisabolol, butyl methoxy dibenzoylmethane, 1-methylhydantoin-2-imide, creatine, pre-prepared liquid III and pre-prepared liquid IV, and uniformly stirring to obtain the skin care emulsion.

The invention has the beneficial effects that: the skin care emulsion can effectively aim at the target effect of reasons for formation of pouches, promotes formation of dermal matrix components of skin such as collagen and the like by promoting cell differentiation and collagen synthesis, improves skin elasticity, and can promote regeneration of skin around eyes, so that melanin around eyes can be effectively removed, pouches are eliminated, the skin problem of eyes is quickly removed, the eyes are bright and shiny, the skin care emulsion is warm and safe to the skin, has no irritation, can prevent and reduce generation of wrinkles of eyes, enhances skin elasticity, reduces wrinkle relaxation and the like after long-term use, and comprehensively saves fragile eye skin.

Drawings

FIG. 1 is a bar graph of the results of the detection of the effect of cosmetic polypeptides on fine lines of the eye;

FIG. 2 is a bar graph of the results of the measurement of the effect of cosmetic polypeptides on the elasticity of the skin at the canthus;

FIG. 3 is a line graph of the detection result of the effect of the beauty treatment polypeptide on the pouch part.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further explained below by combining the specific drawings.

Example 4

The embodiment provides an anti-aging skin care emulsion for eyes and a preparation method thereof, wherein the skin care emulsion comprises the following raw materials in percentage by mass: 4% of acetyl tetrapeptide-5, 4% of palmitoyl tripeptide-38, 4% of palmitoyl pentapeptide-4, 4% of carnosine, 4% of acetyl hexapeptide-8, 4% of snake venom-like peptide, 0.5% of polyglycerol-6 distearate, 0.5% of jojoba lipids, 0.5% of polyglycerol-3 beeswax, 0.5% of cetyl alcohol, 3% of squalane, 3% of isononyl isononanoate, 3% of cyclopolydimethylsiloxane, 5% of polydimethylsiloxane, 1% of shea butter, 0.5% of xanthan gum, 1% of sodium hyaluronate, 5% of methyl propylene glycol, 5% of 1, 3-propylene glycol, 2% of betaine, 0.2% of p-hydroxyacetophenone, 1% of butanediol, 1% of astragalus membranaceus root extract, 1% of saposhnikovia root extract, 1% of calendula flower extract, 1% of albizia flower extract, 1% of gastrodia root extract, Dipotassium glycyrrhizinate 0.5%, caprylic/capric triglyceride 0.5%, 1, 2-pentanediol 2%, phenethylresorcinol 0.2%, bisabolol 0.5%, butyl methoxydibenzoylmethane 0.5%, 1-methylhydantoin-2-imide 0.5%, creatine 0.5%.

The preparation method of the anti-aging skin care emulsion for eyes comprises the following steps:

(1) adding polyglycerol-6 distearate, jojoba esters, polyglycerol-3 beeswax, cetyl alcohol, squalane, isononyl isononanoate, cyclomethicone, dimethicone and shea butter into an oil phase pot according to the mass ratio, heating to about 85 ℃, and stirring until completely dissolving to obtain a first pre-prepared solution;

(4) pumping the pre-prepared liquid II into an emulsifying pot, slowly pumping the pre-prepared liquid I in the stirring process, homogenizing for 5min, then adding p-hydroxyacetophenone when cooling to about 60 ℃ while stirring, adding betaine, butanediol, a skin conditioner, dimethyl glycyrrhizinate, caprylic/capric triglyceride, 1, 2-pentanediol, phenethylresorcinol, bisabolol, butyl methoxy dibenzoyl methane, 1-methylhydantoin-2-imide, creatine and the pre-prepared liquid III when continuing to stir and cool to about 40 ℃, and stirring uniformly to obtain the skin care emulsion.

Example 5

The embodiment provides an anti-aging skin care emulsion for eyes and a preparation method thereof, wherein the skin care emulsion comprises the following raw materials in percentage by mass: 4% of acetyl tetrapeptide-5, 4% of palmitoyl tripeptide-38, 4% of palmitoyl pentapeptide-4, 4% of carnosine, 4% of acetyl hexapeptide-8, 4% of snake venom-like peptide, 0.5% of polyglycerol-6 distearate, 0.5% of jojoba lipids, 0.5% of polyglycerol-3 beeswax, 0.5% of cetyl alcohol, 3% of squalane, 3% of isononyl isononanoate, 3% of cyclopolydimethylsiloxane, 5% of polydimethylsiloxane, 1% of shea butter, 4% of aesculus chinensis, 0.5% of xanthan gum, 1% of sodium hyaluronate, 5% of methyl propylene glycol, 1, 3-propylene glycol 5%, 2% of betaine, 0.2% of p-hydroxyacetophenone, 1% of butanediol, 1% of astragalus membranaceus root extract, 1% of saposhnikovia root extract, 1% of calendula extract, 1% of albizia flower extract, 1% of gastrodia root extract, Dipotassium glycyrrhizinate 0.5%, caprylic/capric triglyceride 0.5%, 1, 2-pentanediol 2%, phenethylresorcinol 0.2%, bisabolol 0.5%, butyl methoxydibenzoylmethane 0.5%, 1-methylhydantoin-2-imide 0.5%, creatine 0.5%.

(5) pumping the pre-prepared liquid II into an emulsifying pot, slowly pumping the pre-prepared liquid I in the stirring process, homogenizing for 5min, then adding p-hydroxyacetophenone when the temperature is reduced to about 60 ℃ while stirring, continuously stirring and cooling to about 40 ℃, adding betaine, butanediol, a skin conditioner, dimethyl glycyrrhizinate, caprylic/capric triglyceride, 1, 2-pentanediol, phenethylresorcinol, bisabolol, butyl methoxy dibenzoyl methane, 1-methylhydantoine-2-imide, creatine, a pre-prepared liquid III and a pre-prepared liquid IV, and uniformly stirring to obtain the skin care emulsion.

Comparative example 2

The test example provides a skin care emulsion and a preparation method thereof, and the skin care emulsion comprises the following raw materials in percentage by mass: polyglycerol-6 distearate 1%, jojoba esters 1%, polyglycerol-3 beeswax 1%, cetyl alcohol 1%, squalane 3%, isononyl isononanoate 5%, cyclomethicone 4%, dimethicone 2%, shea butter 1%, xanthan gum 0.5%, sodium hyaluronate 0.5%, methyl propylene glycol 4%, 1, 3-propanediol 4%, betaine 4%, p-hydroxyacetophenone 0.1%, butylene glycol 0.5%, astragalus membranaceus root extract 1%, radix sileris root extract 1%, calendula extract 1%, albizia flower extract 1%, gastrodia root extract 1%, dipotassium glycyrrhizinate 0.5%, caprylic/capric triglyceride 0.05%, 1, 2-pentanediol 5%, phenethylresorcinol 1%, bisabolol 0.05%, butyl methoxydibenzoylmethane 1%, sodium hyaluronate 1%, and mixtures thereof, 1% of 1-methylhydantoin-2-imide and 1% of creatine.

(3) pumping the pre-prepared liquid II into an emulsifying pot, slowly pumping the pre-prepared liquid I in the stirring process, homogenizing for 5min, then adding p-hydroxyacetophenone when cooling to about 60 ℃ while stirring, adding betaine, butanediol, a skin conditioner, dimethyl glycyrrhizinate, caprylic/capric triglyceride, 1, 2-pentanediol, phenethylresorcinol, bisabolol, butyl methoxy dibenzoyl methane, 1-methylhydantoin-2-imide and creatine when continuing to stir and cooling to about 40 ℃, and uniformly stirring to obtain the skin care emulsion.

Test example 1: influence of skin care lotion on anti-aging effect of subacute aging mouse model

a. Molding: 25 Kunming Mice were randomly and averagely divided into 5 groups, each group consisting of a blank group, examples 4 to 5 groups, comparative example 2 group and a control group, and 5 groups were prepared by the D-galactose-induced subacute senescence method (see the literature: Yang Chunying, Xu Bin, Sun Yin. Effects of Acupuncure and Moxibuson MDA, GSH-Px, and Hyp in the Skin of Senile Mice [ J ]. Acunct. Tuina. Sci,2011,9(3):143.) by injecting 12.5% by mass of D-galactose under the back of the neck of all Mice except the blank group, injecting the blank group with an equal amount of physiological saline instead of D-galactose 1 time per day for 42 consecutive days.

b. And (3) intervention: the hair on the back of the mouse was removed to expose the skin, and from the 20 th day of injection, the skin on the back of the mouse was washed twice a day in the morning and evening with clean water, and then the corresponding group of mice was wiped with the skin care lotions of examples 4 to 5 and comparative example 2, and the control was washed with clean water.

c. Sample treatment and detection: after 42 days of treatment, the mice are killed, 0.5g of skin tissues subjected to intervention treatment on the backs of the mice are taken, rinsed by physiological saline, wiped and weighed; cutting skin tissue, adding into ice physiological saline for homogenizing to obtain serous fluid, centrifuging at 3500rpm for 20min, collecting supernatant, and using for sample for measuring skin tissue LF (lipofuscin) content, T-AOC (total antioxidant activity) activity and HYP (hydroxyproline) content.

LF is a remaining trace of tissue cells after being damaged by free radicals and is the expression of organism aging, and the larger the LF value is, the more obvious the organism aging degree is; T-AOC reflects all antioxidants in the skin and is used for reflecting the index of whether the skin is good or not, and the larger the value of T-AOC is, the weaker the skin aging degree is; HYP is a major and relatively constant non-essential amino acid in collagen or collagen fibers, and a higher HYP content indicates that the higher the collagen or collagen fibers content, the better the skin elasticity and the weaker the aging degree. In the experiment, the LF content, the T-AOC activity and the HYP content of skin tissues are measured by adopting an LF detection kit, a T-AOC detection kit and a HYP detection kit of Nanjing institute of bioengineering, and the detection methods are described in kit specifications.

Table 1 shows the results of the skin tissue aging performance test of the subacute aging mouse model after different skin care emulsion treatments

Group of	Number of	LF(μg/g)	T-AOC (vitality unit)	HYP(μg/ml)
					Blank group	5	0.425	38.43	0.73
Example 4	5	0.731	26.28	0.66
					Example 5	5	0.701	27.73	0.63
Comparative example 2	5	0.938	28.16	0.45
					Control group	5	1.032	21.75	0.35

As can be seen in table 1: the addition of the beauty polypeptide can obviously reduce the LF content in skin tissues of an aging model mouse, improve the T-AOC and HYP contents, and shows that the addition of the beauty polypeptide can obviously relieve the aging of the mouse skin.

Test example 2

12 female volunteers aged 35-45 years were selected and the 24 volunteers were randomly divided into 4 groups of 3 persons each. After the group 4 had washed their face with clear water every morning and evening, the skin care lotions of examples 4-5 and test examples 1-2 were applied to the skin around one eye and the other eye was left untreated and continuously applied for 1 month.

Eye fine line detection

The eye fine lines were analyzed by using a human skin rapid optical imaging system Primospico (GFM corporation, germany), and the arithmetic average Ra of the peaks on the contour line over the entire test length range, the square root Rq of the average of the squares of the peaks on the contour line over the entire test length range, and the maximum peak Rz on the contour line over the entire test length range were determined. The smaller the three parameters, the better the skin and the fewer wrinkles. Averaging the parameter values of the same group, and calculating the fine grain difference values delta Ra, delta Rq and delta Rz between the treated eyes and the untreated eyes:

Δ Ra-average value of Ra in non-treated eyes-average value of Ra in treated eyes

Δ Rq-mean value of non-treated-mean value of Rq

The results are shown in table 2 below:

fig. 1 is a bar chart of the detection result of the effect of the beauty polypeptide on the fine lines of the eyes, and it can be seen from fig. 1 and table 2 that the beauty polypeptide has an obvious effect on improving the fine lines of the eyes.

Canthus skin elasticity detection

Skin elasticity of the skin at the back of the eye was measured using a Cutomer (model MPA580, manufactured by Courage + Khazaka, Germany) and evaluated by Q1 and R2, wherein Q1 is the ratio of the elastic force without negative pressure to the maximum tensile area with negative pressure, R2 is the ratio of the elastic force without negative pressure to the maximum tensile value with negative pressure, and the closer the values of Q1 and R2 are to 1, the better the skin elasticity is. The values of the parameter of the same group are averaged, and the value of the elastic difference between the treated eye and the untreated eye, Δ Q1, Δ R2:

Δ Q1-mean treated eye Q1-mean non-treated eye Q1

Δ R2-mean treated eye R2-mean non-treated eye R2

The results are shown in table 3 below:

fig. 2 is a bar chart of the results of detecting the effect of the beauty polypeptide on the skin elasticity of the canthus, and it can be seen from fig. 2 and table 3 that the addition of the beauty polypeptide has a very significant curative effect on improving the skin elasticity.

(III) Ocular pouch detection

The pouch site was analyzed by a laser doppler blood flow meter (manufactured by Perimed, sweden), and the perfusion quantity Q of blood flow in the pouch site was measured as an index for evaluating the severity of pouch symptoms. The larger the blood perfusion amount is, the stronger the blood circulation capability of the skin is, and the weaker the bags under the eyes, the average value of the parameter values of the same group is taken. Averaging the parameter values of the same group, and calculating the difference value delta Q of the blood perfusion amount between the treated eye and the non-treated eye:

q mean value for treated eye-Q mean value for non-treated eye

The results are shown in table 4 below:

group of	Treatment of	Non-treatment of	△Q
				Example 4	49.17	42.85	6.32
Example 5	63.22	56.42	6.80
				Comparative example 2	65.81	62.17	3.64

Fig. 3 is a line graph of the detection result of the influence of the beauty polypeptide on the pouch part, and as can be seen from fig. 3 and table 4, the addition of the beauty polypeptide can significantly improve the blood perfusion amount of the pouch part and the eye swelling feeling, and compared with the case that the polypeptide group is not added, the effect can be improved by 75%, and the difference is very significant. Meanwhile, the addition of the aesculus hippocastanum has certain effect on improving the pouch, and as compared with examples 4 and 5, the effect is improved by 7.9% by independently adding the aesculus hippocastanum.

The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. The anti-aging skin care emulsion for the eyes comprises the following raw materials in percentage by mass: 4% of acetyl tetrapeptide-5, 4% of palmitoyl tripeptide-38, 4% of palmitoyl pentapeptide-4, 4% of carnosine, 4% of acetyl hexapeptide-8, 4% of snake venom-like peptide, 0.5% of polyglycerol-6 distearate, 0.5% of jojoba lipids, 0.5% of polyglycerol-3 beeswax, 0.5% of cetyl alcohol, 3% of squalane, 3% of isononyl isononanoate, 3% of cyclopolydimethylsiloxane, 5% of polydimethylsiloxane, 1% of shea butter, 4% of aesculus chinensis, 0.5% of xanthan gum, 1% of sodium hyaluronate, 5% of methyl propylene glycol, 1, 3-propylene glycol 5%, betaine 2%, 0.2% of p-hydroxyacetophenone, 1% of butanediol, 1% of astragalus membranaceus root extract, 1% of saposhnikovia root extract, 1% of calendula flower extract, 1% of albizia flower extract, 1% of gastrodia root extract, Dipotassium glycyrrhizinate 0.5%, caprylic/capric triglyceride 0.5%, 1, 2-pentanediol 2%, phenethylresorcinol 0.2%, bisabolol 0.5%, butyl methoxy dibenzoylmethane 0.5%, 1-methylhydantoin-2-imide 0.5%, creatine 0.5%, and water in appropriate amount;

(5) pumping the second pre-prepared solution into an emulsifying pot, slowly pumping the first pre-prepared solution in the stirring process, homogenizing for 5min, then adding p-hydroxyacetophenone when the temperature is reduced to 60 ℃ while stirring, continuously stirring and reducing the temperature to 40 ℃, adding betaine, butanediol, a radix astragali extract, a radix sileris extract, a calendula extract, an albizia flower extract, a rhizoma gastrodiae extract, dipotassium glycyrrhizinate, caprylic/capric triglyceride, 1, 2-pentanediol, phenethyl resorcinol, bisabolol, butyl methoxy dibenzoyl methane, 1-methylhydantoin-2-imide, creatine, a third pre-prepared solution and a fourth pre-prepared solution, and uniformly stirring to obtain the skin care emulsion.