CN1098089C - Medicine for treating hepatitis and liver fibrosis, and method for preparing same - Google Patents
Medicine for treating hepatitis and liver fibrosis, and method for preparing same Download PDFInfo
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- CN1098089C CN1098089C CN98101673A CN98101673A CN1098089C CN 1098089 C CN1098089 C CN 1098089C CN 98101673 A CN98101673 A CN 98101673A CN 98101673 A CN98101673 A CN 98101673A CN 1098089 C CN1098089 C CN 1098089C
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Abstract
The present invention relates to a medicament for treating hepatitis and hepatic fibrosis and a manufacture method thereof. The medicament is characterized in that the medicament for treating hepatitis and hepatic fibrosis is mainly prepared from raw materials by the following parts by weight: 1 to 50 parts of safflower, 1 to 100 parts of red sage root, 1 to 50 parts of angelica, 1 to 50 parts of bupleurum root, 1 to 100 parts of astragalus root, 1 to 50 parts of nutgrass flatsedge, 1 to 50 parts of white paeony root, 1 to 50 parts of herba artemisiae, 1 to 30 parts of licorice root, 1 to 50 parts of indigowoad root, 1 to 100 parts of suberect spatholobus stem, 1 to 50 parts of immature bitter orange, 1 to 30 parts of Chinese caterpillar fungus, 1 to 50 parts of common leafflower herb with root and 1 to 30 parts of ganoderma lucidum. The medicament has the advantages of unique formula and technique and good therapeutic effect. Medicament powder can be processed into the different dosage forms of oral liquid, particles, etc. according to requirements.
Description
The present invention relates to a kind of medicament and manufacture method thereof for the treatment of hepatitis and hepatic fibrosis, particularly a kind of Chinese medicine preparation and manufacture method thereof for the treatment of hepatitis and hepatic fibrosis.
Hepatitis is a kind of common infectious disease, though the Chinese patent medicine of some treatment hepatitis is arranged at present, curative effect is unsatisfactory, and therefore knock-on rate height, is necessary to provide a kind of treatment hepatitis eutherapeutic medicament.
The object of the invention provides a kind of medicament for the treatment of hepatitis and hepatic fibrosis, this medicine good effect, manufacture method uniqueness, suitable.
For achieving the above object, the present invention takes following design: the medicament of this treatment hepatitis and hepatic fibrosis is that the raw material of following row weight portion is made: Flos Carthami 1-50 part, Radix Salviae Miltiorrhizae 1-100 part, Radix Angelicae Sinensis 1-50 part, Radix Bupleuri 1-50 part, Radix Astragali 1-100 part, Rhizoma Cyperi 1-50 part, Radix Paeoniae Alba 1-50 part, Herba Artemisiae Scopariae 1-50 part, Radix Glycyrrhizae 1-30 part, Radix Isatidis 1-50 part, Caulis Spatholobi 1-100 part, Fructus Aurantii Immaturus 1-50 part, Cordyceps 1-39 part, Herba Phyllanthi Urinariae 1-50 part, Ganoderma 1-30 part.
The method of treatment hepatitis and hepatic fibrosis medicament is that carry out the following step: Flos Carthami extracts volatile oil with the way of distillation according to above-mentioned each Chinese medicine proportioning; With Radix Bupleuri, the Radix Astragali, Caulis Spatholobi, Herba Phyllanthi Urinariae, Rhizoma Cyperi, Herba Artemisiae Scopariae, Radix Isatidis, the Radix Paeoniae Alba, Fructus Aurantii Immaturus, liquorice beverage are carried, and are condensed into extractum; Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae alcohol extraction also are condensed into extractum; Cordyceps, Ganoderma powder are broken into fine powder, fine powder are added in above-mentioned two kinds of extractum again, and vacuum drying, pulverizing spray into the volatile oil that is extracted by Flos Carthami with alcohol-soluble in the medicated powder.
15 flavor Chinese medicines have been adopted among the present invention, the Flos Carthami that blood circulation promoting and blood stasis dispelling is wherein arranged, the Chinese medicine that also have dispersing the stagnated live-QI to relieve the stagnation of QI, protects the liver, as Radix Bupleuri, Rhizoma Cyperi, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, the Chinese medicine of antimicrobial antiphlogistic such as the Radix Astragali, Herba Artemisiae Scopariae, Radix Isatidis, Radix Glycyrrhizae, Cordyceps, the Chinese medicine of blood circulation promoting and enriching has Radix Angelicae Sinensis, Caulis Spatholobi, the Fructus Aurantii Immaturus of dispelling the stagnated QI intestinal stasis relieving etc.
In the above-mentioned Chinese medicine, adopted different extracts to form this prescription, the volatile oil that the employing steam distillation that has extracts; The extractum that the water extract of the employing routine that has, ethanol extract obtain through distilling under reduced pressure; Has plenty of the direct grind into powder of crude drug etc.
The invention will be further described below in conjunction with embodiment.
Embodiment 1:
Get the Flos Carthami of 30g,, extract volatile oil by the 62nd page of essential oil extraction method of mentioning of nineteen ninety-five version Chinese Pharmacopoeia.
Get Radix Salviae Miltiorrhizae 50g, Radix Angelicae Sinensis 50g is with 60% alcohol reflux of 6 times of doses, 2 hours time, after the filtration, in precipitation, add the ethanol (60%) of 4 times of precipitation weight again, extracted 1.5 hours, and refiltered after extracting solution leaves standstill, the merging filtrate distilling under reduced pressure is the extractum of 1.25-1.3 to proportion.
Take by weighing Radix Bupleuri 30g, Radix Astragali 80g, Rhizoma Cyperi 60g, Radix Paeoniae Alba 50g, Herba Artemisiae Scopariae 8g, Radix Glycyrrhizae 20g, Radix Isatidis 80g, Herba Phyllanthi Urinariae 50g, Fructus Aurantii Immaturus 30g, Caulis Spatholobi 80g, above-mentioned Chinese medicine is for the first time with the water extraction of 12 times of medicine weight 2 hours, extract once again after the filtration, its water consumption is 10 times of medicine weight, 1.5 hours time, extracted twice liquid mixes, and it is 1.25-1.3 that distilling under reduced pressure is concentrated into proportion.
Cordyceps 50g, Ganoderma 50g are ground into fine powder, are added to and above-mentionedly extract respectively, concentrate in the extractum obtain through water, alcohol, vacuum drying, pulverizing (100 order), dry fine powder.
The above-mentioned volatile oil that is extracted by Flos Carthami is dissolved in ethanol, sprays into after the dissolving in the above-mentioned medicated powder, this medicated powder can be made oral liquid, granule, capsule and tablet etc.Wherein most convenient can be taken for incapsulating.
Advantage of the present invention: because prescription and technology uniqueness can be processed into different agent after making medicinal powder as required Type, this medicine good effect.
Claims (4)
1, a kind of medicament for the treatment of hepatitis and hepatic fibrosis is characterized in that: it is that the raw material of following row weight portion is made: Flos Carthami 1-50 part, Radix Salviae Miltiorrhizae 1-100 part, Radix Angelicae Sinensis 1-50 part, Radix Bupleuri 1-50 part, Radix Astragali 1-100 part, Rhizoma Cyperi 1-50 part, Radix Paeoniae Alba 1-50 part, Herba Artemisiae Scopariae 1-50 part, Radix Glycyrrhizae 1-30 part, Radix Isatidis 1-50 part, Caulis Spatholobi 1-100 part, Fructus Aurantii Immaturus 1-50 part, Cordyceps 1-39 part, Herba Phyllanthi Urinariae 1-50 part, Ganoderma 1-30 part.
2, a kind of method of making described treatment hepatitis of claim 1 and hepatic fibrosis medicament, it is characterized in that: according to above-mentioned each Chinese medicine proportioning, carry out the following step: Flos Carthami extracts volatile oil with the way of distillation; Radix Bupleuri, the Radix Astragali, Caulis Spatholobi, Herba Phyllanthi Urinariae, Rhizoma Cyperi, Herba Artemisiae Scopariae, Radix Isatidis, the Radix Paeoniae Alba, Fructus Aurantii Immaturus, liquorice beverage are carried, and be condensed into extractum; Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae alcohol extraction also are condensed into extractum; Cordyceps, Ganoderma powder are broken into fine powder, fine powder are added in above-mentioned two kinds of extractum again, and vacuum drying, pulverizing spray into the volatile oil that is extracted by Flos Carthami with alcohol-soluble in the medicated powder.
3, the manufacture method of the medicament of treatment hepatitis according to claim 2 and hepatic fibrosis, it is characterized in that: the number of times that described water is carried is twice, the water yield is respectively 12 times of doses, 10 times, extraction time is respectively after 2 hours, 1.5 hours, water extract leave standstill filtration, is evaporated to the extractum that proportion is 1.25-1.3.
4, according to the manufacture method of the medicament of claim 2 or 3 described treatment hepatitis and hepatic fibrosis, it is characterized in that: described alcohol extraction is adopted 60% alcohol reflux twice, the ethanol consumption is 6 times, 4 times of dose, extraction time was respectively 2 hours, 1.5 hour, after alcohol extract leaves standstill filtration, be evaporated to the extractum that proportion is 1.25-1.3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98101673A CN1098089C (en) | 1998-04-28 | 1998-04-28 | Medicine for treating hepatitis and liver fibrosis, and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98101673A CN1098089C (en) | 1998-04-28 | 1998-04-28 | Medicine for treating hepatitis and liver fibrosis, and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1233477A CN1233477A (en) | 1999-11-03 |
| CN1098089C true CN1098089C (en) | 2003-01-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98101673A Expired - Lifetime CN1098089C (en) | 1998-04-28 | 1998-04-28 | Medicine for treating hepatitis and liver fibrosis, and method for preparing same |
Country Status (1)
| Country | Link |
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| CN (1) | CN1098089C (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1321675C (en) * | 2000-11-24 | 2007-06-20 | 张志祥 | Liver-spleen capsule and its preparing process |
| WO2004096252A1 (en) * | 2003-04-25 | 2004-11-11 | Primavera Biosciences, Inc. | Compositions and methods for weight loss |
| US20060110479A1 (en) * | 2004-11-24 | 2006-05-25 | Mitra Shankar K | Natural composition for curing hepatitis-B, methods for making the same and pharmaceutical formulations thereof |
| CN101199606B (en) * | 2006-12-14 | 2012-05-09 | 北京因科瑞斯生物制品研究所 | Medicament for treating liver disease |
| CN101843704B (en) * | 2009-10-16 | 2011-08-31 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating chronic hepatitis |
| CN101850035A (en) * | 2010-05-31 | 2010-10-06 | 拉萨市高原生物研究所 | Tibetan medicine-containing composition with anti-hepatic fibrosis function, preparation method thereof and application thereof in preparing anti-hepatic fibrosis medicines |
| CN102283956B (en) * | 2011-07-31 | 2013-01-16 | 郭清军 | Orally administered drug for treating chronic hepatitis |
| CN103142735B (en) * | 2013-03-09 | 2014-07-23 | 河北工程大学 | Traditional Chinese medicine oral liquid for treating duck virus hepatitis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112834A (en) * | 1994-08-29 | 1995-12-06 | 郭约翰 | Oral liquid for curing hepatitis B, and method for prodn. of same |
| CN1149489A (en) * | 1996-09-10 | 1997-05-14 | 吴荫福 | Recovering powder for hepatitis B |
-
1998
- 1998-04-28 CN CN98101673A patent/CN1098089C/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112834A (en) * | 1994-08-29 | 1995-12-06 | 郭约翰 | Oral liquid for curing hepatitis B, and method for prodn. of same |
| CN1149489A (en) * | 1996-09-10 | 1997-05-14 | 吴荫福 | Recovering powder for hepatitis B |
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| Publication number | Publication date |
|---|---|
| CN1233477A (en) | 1999-11-03 |
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Owner name: BEIJING BEIDA WEIMING BIOLOGY ENGINEERING GROUP C Free format text: FORMER OWNER: XINDIYA MEDICINE NEW TECH. DEVELOPMENT CO., LTD., TIANJIN CITY Effective date: 20040211 |
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Effective date of registration: 20040211 Address after: No. 100085 West Road, Beijing, Peking University biological city, 39 Patentee after: Beijing sinobioway Group Co., Ltd. Address before: 300240 Tianjin City, Hebei District Jianchang Road No. 54 days of life engineering company Patentee before: Xindiya Medicine New Tech. Development Co., Ltd., Tianjin City |