CN100512855C - Method for preparing medication of gastrodia tuber and tuber of multiflower knotweed - Google Patents
Method for preparing medication of gastrodia tuber and tuber of multiflower knotweed Download PDFInfo
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- CN100512855C CN100512855C CNB2004100466277A CN200410046627A CN100512855C CN 100512855 C CN100512855 C CN 100512855C CN B2004100466277 A CNB2004100466277 A CN B2004100466277A CN 200410046627 A CN200410046627 A CN 200410046627A CN 100512855 C CN100512855 C CN 100512855C
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Abstract
A Chinese medicine for the middle-aged and old patients of cardiovascular diseases is prepared from 14 Chinese-medicinal materials including fleece flower root, rehmannia root, red sage root, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.
Description
Affiliated technical field:
The invention belongs to pharmaceutical technology, particularly a kind of preparation method of utilizing Chinese herbal medicine resources such as Rhizoma Gastrodiae, Radix Polygoni Multiflori to produce the gastrodia tuber and fleece-flower root medicine.
Background technology:
Rhizoma Gastrodiae, Radix Polygoni Multiflori are dizzy for treatment headache since ancient times, nourishing the liver and kidney, crow must hair color famous medicine, key medicine, a lot of ancient prescriptions, classics side are all as monarch drug, as TIANMA GOUTENG YIN, gastrodia elata-cortex capsule, Qibao Meiran Dan etc., the function nourishing blood to stop wind syndrome, nourishing the liver and kidney is favored by consumer deeply.But this gastrodia tuber and fleece-flower root medicine also has only Tabules at present, can not satisfy the demand that the patient takes medicine and cures the disease, the patient takes and carries for convenience, give full play to the curative effect of medicine therapies such as Rhizoma Gastrodiae, Radix Polygoni Multiflori, industry scientific research personnel is thinking hard, is trying every possible means, be desirably under the prerequisite of guaranteeing drug quality, make great efforts to develop the novel form that makes things convenient for patient to carry to take medicine, serve extensive patients.
The objective of the invention is at above-mentioned situation, be intended to the effective Chinese material medicine resources such as Rhizoma Gastrodiae, Radix Polygoni Multiflori that utilize, give full play to the medical value of Chinese medicinal herbses such as Rhizoma Gastrodiae, Radix Polygoni Multiflori, improve biological availability, and a kind of Rhizoma Gastrodiae of development, the preparation method of Radix Polygoni Multiflori medicine.
The method that the present invention finishes is to be guidance with traditional Chinese medical theory, according to the hepatic and renal YIN deficiency cause of disease of the traditional Chinese medical science to symptoms such as headache, dizzy, alopecia, poliosis, plus-minus prescription on the basis of the tradition of suiting the medicine to the illness name side TIANMA GOUTENG YIN, YIGUANJIAN, ERZHI WAN, SIWU TANG, choosing Chinese medicinal herbses such as Rhizoma Gastrodiae, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, stir-baked FRUCTUS TRIBULI, Folium Mori, Herba Ecliptae, Fructus Ligustri Lucidi, the Radix Paeoniae Alba, Rhizoma Polygonati, Radix Glycyrrhizae is basic recipe.Earlier above-mentioned Rhizoma Gastrodiae, Rhizoma Chuanxiong, Radix Polygoni Multiflori powder are broken into fine powder, sieve, mixing is standby; Radix Angelicae Sinensis, the Radix Angelicae Dahuricae are extracted volatile oil, extract together extracting in water 2～3 times of medicinal residues behind the volatile oil and all the other each medicines, each 60～180 minutes, merge extractive liquid,, filtration, filtrate decompression is spray dried to extract powder after concentrating, and adds above-mentioned medicated powder and volatile oil again, mixing, add various excipient and promptly make traditional Chinese medicine preparation product of the present invention, standby.
Advantage of the present invention is: one, produce the gastrodia tuber and fleece-flower root medicine with Chinese medicinal herbses such as Rhizoma Gastrodiae, Radix Polygoni Multiflori, the raw material source is sufficient, and processing technology is uncomplicated, product cost is not high, has both helped Chinese medicine process unit and has produced the exploitation tcm product, be of value to the patient again and take, market prospect is wide; Two, this gastrodia tuber and fleece-flower root medicine can be developed the gastrodia tuber and fleece-flower root medicine of multiple dosage form, makes various dosage forms, for patient's medication provides the convenience of selecting dosage form, benefits the patient and takes and carry; Three, cardiovascular disease mostly is the old people, and the medicine difficulty of swallowing can reduce the dose of medicine with the medicine of this method preparation, easy disintegrating more in gastrointestinal, and onset speed is fast, bioavailability height, better efficacy; Four, the huge market demand can produce good economic benefit and social benefit.
Embodiments of the invention one: get Rhizoma Gastrodiae 3%, Rhizoma Chuanxiong 0.5%, Radix Polygoni Multiflori 7%, be ground into fine powder, sieve, mixing, standby; Get Radix Angelicae Sinensis 7%, the Radix Angelicae Dahuricae 3%, medicinal residues behind the extraction volatile oil and Radix Rehmanniae Preparata 7%, Herba Ecliptae 7%, Rhizoma Polygonati 10%, Radix Salviae Miltiorrhizae 7%, stir-fry disease multitude 3%, Fructus Ligustri Lucidi 10%, Radix Glycyrrhizae 0.5%, Folium Mori 3%, the Radix Paeoniae Alba 10%, extracting in water 2～3 times, each 180 minutes, merge extractive liquid,, filtration, filtrate decompression is spray dried to extract powder after concentrating, add above-mentioned standby Rhizoma Gastrodiae, Rhizoma Chuanxiong, Radix Polygoni Multiflori fine powder again, mixing, ethanol with 95% is made granule, drying, granulate, spray into volatile oil, filled capsules is made capsule.
Embodiments of the invention two: get all the used Chinese medicine raw material ready.Get Rhizoma Gastrodiae 7%, Rhizoma Chuanxiong 3%, Radix Polygoni Multiflori 10%, be ground into fine powder, sieve mixing; Get Radix Angelicae Sinensis 10%, the Radix Angelicae Dahuricae 7%, medicinal residues and Radix Rehmanniae Preparata 1.0% behind the extraction volatile oil, Herba Ecliptae 1.0%, Rhizoma Polygonati 13%, Radix Salviae Miltiorrhizae 10%, parched Fructus Tribuli 7%, Fructus Ligustri Lucidi 13%, Radix Glycyrrhizae 3%, Folium Mori 7%, the Radix Paeoniae Alba 13%, extracting in water 2 times, each 60～180 minutes, merge extractive liquid,, filtration, filtrate decompression is spray dried to extract powder after concentrating, add standby Rhizoma Gastrodiae, Rhizoma Chuanxiong, Radix Polygoni Multiflori fine powder again, mixing, ethanol with 95% is made granule, drying, granulate, spray into volatile oil, filled capsules is made capsule; Tabletting, coating are made tablet or granule.
In sum, the amount ranges of forming each Chinese medicinal ingredients of this medicine is respectively: Rhizoma Gastrodiae 3～7%, Rhizoma Chuanxiong 0.5～3%, Radix Polygoni Multiflori 7～10%, Radix Rehmanniae Preparata 7～10%, Radix Angelicae Sinensis 7～10%, Herba Ecliptae 7～10%, Rhizoma Polygonati 10～13%, the Radix Angelicae Dahuricae 3～7%, Radix Salviae Miltiorrhizae 7～10%, to fry disease multitude 3～7%, Fructus Ligustri Lucidi 10～13%, Radix Glycyrrhizae 0.5～3%, Folium Mori 3～7%, the Radix Paeoniae Alba be 10～13%.
This medicine can be made pill, tablet, capsule, granule, microcapsule, drop pill, mixture, slow releasing agent, injection etc.
Claims (2)
1, a kind of gastrodia tuber and fleece-flower root medicine is made up of Rhizoma Gastrodiae, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, stir-baked FRUCTUS TRIBULI, Folium Mori, Herba Ecliptae, Fructus Ligustri Lucidi, the Radix Paeoniae Alba, Rhizoma Polygonati, Radix Glycyrrhizae, it is characterized in that the amount ranges of described each composition is respectively:
Rhizoma Gastrodiae 3%-7% Radix Angelicae Dahuricae 3%-7% Radix Polygoni Multiflori 7%-10%
Radix Rehmanniae Preparata 7%-10% Radix Salviae Miltiorrhizae 7%-10% Rhizoma Chuanxiong 0.5%-3%
Radix Angelicae Sinensis 7%-10% stir-baked FRUCTUS TRIBULI 3%-7% Folium Mori 3%-7%
Herba Ecliptae 7%-10% Fructus Ligustri Lucidi 10%-13% Radix Paeoniae Alba 10%-13%
Rhizoma Polygonati 10%-13% Radix Glycyrrhizae 0.5%-3%.
2,, it is characterized in that described gastrodia tuber and fleece-flower root medicine has pill, tablet, capsule, granule, microcapsule, drop pill, mixture, slow releasing agent and injection dosage form according to the described gastrodia tuber and fleece-flower root medicine of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100466277A CN100512855C (en) | 2004-07-28 | 2004-07-28 | Method for preparing medication of gastrodia tuber and tuber of multiflower knotweed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100466277A CN100512855C (en) | 2004-07-28 | 2004-07-28 | Method for preparing medication of gastrodia tuber and tuber of multiflower knotweed |
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| Publication Number | Publication Date |
|---|---|
| CN1726931A CN1726931A (en) | 2006-02-01 |
| CN100512855C true CN100512855C (en) | 2009-07-15 |
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| CNB2004100466277A Active CN100512855C (en) | 2004-07-28 | 2004-07-28 | Method for preparing medication of gastrodia tuber and tuber of multiflower knotweed |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857321A (en) * | 2015-05-19 | 2015-08-26 | 申洪恩 | Medicine for treating leukotrichia and baldness and preparation method of medicine |
| CN106075104A (en) * | 2016-08-05 | 2016-11-09 | 湖南德海制药有限公司 | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata combined pharmaceutical composition and preparation method thereof |
| CN106138772A (en) * | 2016-08-05 | 2016-11-23 | 湖南德海制药有限公司 | Gastrodia tuber and fleece-flower root combined pharmaceutical composition and preparation technology thereof |
| CN106138773A (en) * | 2016-08-05 | 2016-11-23 | 湖南德海制药有限公司 | A kind of gastrodia tuber and fleece-flower root pharmaceutical composition and preparation technology thereof |
| CN106075103A (en) * | 2016-08-05 | 2016-11-09 | 湖南德海制药有限公司 | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation technology thereof |
| CN106109968A (en) * | 2016-08-05 | 2016-11-16 | 湖南德海制药有限公司 | Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation method thereof |
| CN106237118A (en) * | 2016-08-05 | 2016-12-21 | 湖南德海制药有限公司 | Gastrodia tuber and fleece-flower root pharmaceutical composition and preparation method thereof |
| CN106109969A (en) * | 2016-08-05 | 2016-11-16 | 湖南德海制药有限公司 | A kind of Rhizoma Gastrodiae, Radix Polygoni Multiflori Preparata pharmaceutical composition and preparation method thereof |
-
2004
- 2004-07-28 CN CNB2004100466277A patent/CN100512855C/en active Active
Non-Patent Citations (2)
| Title |
|---|
| 中华人民共和国药典. 国家药典委员会，383，化学工业出版社. 2000 |
| 中华人民共和国药典. 国家药典委员会，383，化学工业出版社. 2000 * |
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| CN1726931A (en) | 2006-02-01 |
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