CN109793855A - A kind of Chinese materia medica preparation and preparation method thereof for treating acute mastitis - Google Patents
A kind of Chinese materia medica preparation and preparation method thereof for treating acute mastitis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese materia medica preparation and preparation method thereof for treating acute mastitis, which includes following raw material: edible tulip, corydalis tuber, bombyx batryticatus, honeysuckle, Prunella vulgaris, Radix Angelicae Sinensis, radix bupleuri, green peel, dandelion, Radix Glycyrrhizae, Radix Astragali, dried orange peel, turtle shell, radix scutellariae, great burdock achene, spina gleditsiae, the seed of cowherb and Fructus Liquidambaris.The resulting Chinese materia medica preparation for treating acute mastitis of the present invention is for acute mastitis pathogenesis, effectively treatment acute mastitis, safe ready, toxic side effect are small, reduce clinical patients expense and the course of disease, its compatibility is reasonable, play clearing heat and detoxicating, dissipating phlegm and removing blood stasis, activating collaterals and eliminating stagnation, soothing the liver the effects of promoting lactation；Preparation method is simple, low in cost.
Description
Technical field
The present invention relates to field of traditional Chinese medicine pharmacy, and in particular to a kind of for treating the Chinese materia medica preparation and its system of acute mastitis
Preparation Method.
Background technique
Mazoitis is the common disease of women, can be divided into acute purulent mammitis, by mammary areola according to the difference of the cause of disease
Fistula, plasma cell mastitis etc., wherein most commonly acute purulent mammitis.Acute purulent mammitis often betides the food in one's mouth
In newborn phase, especially 1~2 month primipara's postpartum, therefore it is called acute nursing period or puerperium suppurative mastitis, Chinese medicine are known as
" acute mastitis ".The disease incidence of primipara's acute mastitis is up to 2%~4%, 1 times more than multipara mazoitis.It not only produces after the onset
Woman's pain is abnormal, and cannot continue lactation, influences the health of baby.
Due to factors such as current environment and life stress, suffer from mazoitis crowd and be gradually expanded, except the gestational period and nursing period
Outside women, women in Development in Puberty is sitting in the white collar women before computer, female that is older, not giving birth to child for a long time
Property have the possibility for suffering from mazoitis, number of patients rises year by year, according to the preliminary statistics national patient about 20,000,000 or more.
In terms for the treatment of, acute mastitis treatment will as early as possible, and early stage mazoitis, can not yet at purulence based on milk inflammation of becoming silted up
With ultrashort wave physical therapy, cooperate Chinese traditional treatment effect more preferable.Existed using clearing heat and detoxicating, the soothing the liver Chinese medicine cooperation gimmick milk ejection promoted lactation more
One week inner dissipation commonly uses Snakegourd Fruit, public English, Radix Rhapontici seu Radix Echinopsis, naze, fritillaria, cornu cerve degelatinatum etc., and low-heat radix bupleuri, high fever adds gypsum, constipation
Add great burdock achene, milk adds Fructus Hordei Germinatus to reduce galactosis.Because of postpartum weakness, it is overweight to avoid bitter cold, should not with Chinese violet, Fructus Forsythiae,
The category of rheum officinale.Duration of medication can continue lactation or strong side feed milk is applied alone.If high fever can cooperate infusion, penicillin, cephalo
Class antibiotic.Pay attention to that a large amount of antibiotic should not be used too early, use antibiotic excessive or too long makes lump difficulty disappear, is easy
Chronic mastitis is changed into, next difficult to treatment zone, therefore, the Chinese materia medica preparation of the exact treatment acute mastitis of exploitation treatment has
Necessity.
Summary of the invention
Aiming at the problems existing in the prior art, the purpose of the present invention is to provide a kind of for treating acute mastitis
Chinese materia medica preparation and preparation method thereof, the Chinese materia medica preparation are directed to acute mastitis pathogenesis, effectively treatment acute mastitis, safety
Conveniently, toxic side effect is small, reduces clinical patients expense and the course of disease, and compatibility is reasonable, plays clearing heat and detoxicating, dissipating phlegm and removing blood stasis, dredging collateral
Dissipating bind, soothing the liver the effects of promoting lactation；Preparation method is simple, low in cost.
In order to achieve the above object, the present invention is achieved by the following scheme.
(1) a kind of for treating the Chinese materia medica preparation of acute mastitis, including following raw material: edible tulip, corydalis tuber, bombyx batryticatus, gold
Honeysuckle flower, Prunella vulgaris, Radix Angelicae Sinensis, radix bupleuri, green peel, dandelion, Radix Glycyrrhizae, Radix Astragali, dried orange peel, turtle shell, radix scutellariae, great burdock achene, spina gleditsiae, king are not
Stay capable and Fructus Liquidambaris.
Preferably, the Chinese materia medica preparation is tablet, granule, capsule.
It is further preferred that the Chinese materia medica preparation is capsule.
Preferably, the dosage of the raw material are as follows: 25-125 parts of edible tulip, 25-125 parts of corydalis tuber, 50-250 parts of bombyx batryticatus, gold and silver
Flower 50-250 parts, 150-350 parts of Prunella vulgaris, 50-250 parts of Radix Angelicae Sinensis, 25-125 parts of radix bupleuri, 25-125 parts of green peel, dandelion 150-
350 parts, 25-125 parts of Radix Glycyrrhizae, 150-350 parts of Radix Astragali, 25-125 parts of dried orange peel, 150-350 parts of turtle shell, 25-125 parts of radix scutellariae, fructus arctii
50-250 parts sub-, 25-125 parts of spina gleditsiae, 50-250 parts of the seed of cowherb and 50-250 parts of Fructus Liquidambaris.
It is further preferred that the dosage of the raw material are as follows: 50-100 parts of edible tulip, 50-100 parts of corydalis tuber, bombyx batryticatus 100-200
Part, 100-200 parts of honeysuckle, 200-300 parts of Prunella vulgaris, 100-200 parts of Radix Angelicae Sinensis, 50-100 parts of radix bupleuri, 50-100 parts of green peel, Pu
Public English 200-300 parts, 50-100 parts of Radix Glycyrrhizae, 200-300 parts of Radix Astragali, 50-100 parts of dried orange peel, 200-300 parts of turtle shell, radix scutellariae 50-
100 parts, 100-200 parts of great burdock achene, 50-100 parts of spina gleditsiae, 100-200 parts of the seed of cowherb and 100-200 parts of Fructus Liquidambaris.
It is further preferred that the dosage of the raw material are as follows: 75 parts of edible tulip, 75 parts of corydalis tuber, 150 parts of bombyx batryticatus, honeysuckle 150
It is part, 250 parts of Prunella vulgaris, 150 parts of Radix Angelicae Sinensis, 75 parts of radix bupleuri, 75 parts of green peel, 250 parts of dandelion, 75 parts of Radix Glycyrrhizae, 250 parts of Radix Astragali, old
75 parts of skin, 250 parts of turtle shell, 75 parts of radix scutellariae, 150 parts of great burdock achene, 75 parts of spina gleditsiae, 150 parts of the seed of cowherb and 150 parts of Fructus Liquidambaris.
It is (two) a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip, corydalis tuber, bombyx batryticatus are ground into fine powder, are sieved, obtain three taste Chinese herbal medicine powders, it is spare；
Step 2, to honeysuckle, Prunella vulgaris, Radix Angelicae Sinensis, radix bupleuri, green peel, dandelion, Radix Glycyrrhizae, Radix Astragali, dried orange peel, turtle shell, radix scutellariae,
Extraction 3 times is added water to cook in great burdock achene, ten five tastes Chinese herbal medicine of spina gleditsiae, the seed of cowherb and Fructus Liquidambaris, filtration merges 3 filtrates,
It is concentrated under reduced pressure into the clear cream that relative density is 1.18~1.20, is cooled to room temperature, obtains liquid extract；
Step 3, add ethyl alcohol to make alcohol content up to 65% in Xiang Suoshu liquid extract, stand 24 hours, filtration, supernatant recycles second
Alcohol is simultaneously concentrated into the thick paste that relative density is 1.30~1.35, is dried under reduced pressure, is ground into fine powder, be sieved, three taste Chinese herbal medicines are added
Powder is uniformly mixed, obtains active pharmaceutical ingredient；
Step 4, it combines the active pharmaceutical ingredient with pharmaceutically acceptable carrier, is made for treating acute mastitis
Chinese materia medica preparation.
Preferably, in step 1, the sieving was 80 mesh screens.
Preferably, described to add water to cook in extraction 3 times in step 2, the amount of water of first time is ten traditional Chinese medicine of the five flavours material amounts
8 times, for the first time decoct temperature be 95~100 DEG C, for the first time decoct time be 1.8~2.2 hours；Secondary plus water
Amount is 6 times of ten traditional Chinese medicine of the five flavours material amounts, and the temperature decocted for second is 95~100 DEG C, the time decocted for second is 0.8~
1.2 hour；The amount of water of third time is 6 times of ten traditional Chinese medicine of the five flavours material amounts, and the temperature that third time decocts is 95~100 DEG C, the
The time decocted three times is 0.8~1.2 hour.
Preferably, in step 2, the temperature of the reduced pressure is 70~80 DEG C, the pressure of reduced pressure is -0.05~-
0.08MPa。
Preferably, in step 2, the detection temperature of the relative density is 60~65 DEG C.
Preferably, in step 3, the temperature of the reduced pressure is 70~80 DEG C, the pressure of reduced pressure is -0.05~-
0.08MPa。
Preferably, in step 3, the detection temperature of the relative density is 60 DEG C.
Preferably, in step 3, the pressure being dried under reduced pressure is -0.05~-0.08MPa.
Preferably, in step 3, the sieving was 80 mesh screens.
Preferably, in step 4, the pharmaceutically acceptable carrier be hydroxypropyl methylcellulose, sodium carboxymethyl starch, dextrin,
Magnesium stearate.
Compared with prior art, the invention has the benefit that
In the resulting Chinese materia medica preparation for treating acute mastitis of the present invention, honeysuckle, dandelion are Fang Zhongwei monarch drug in a prescription,
With antipyretic and antidote functions；Prunella vulgaris, spina gleditsiae, bombyx batryticatus (bran stir-fry), turtle shell (vinegar system) are ministerial drug in side；Radix Angelicae Sinensis, edible tulip, corydalis tuber
For adjutant, there is the carbuncle effect that disappears of invigorating blood circulation；Radix bupleuri, green peel, radix scutellariae, great burdock achene (stir-fry) are all adjutant, common performance dispersing stagnated hepatoqi
Effect；Radix Glycyrrhizae, Radix Astragali, dried orange peel are to make medicine, play removing toxic substances and middle effect；The seed of cowherb is equipped in side, Fructus Liquidambaris plays milk ejection and makees
With；Eight taste of Quan Fangshi, compatibility is reasonable, plays clearing heat and detoxicating, dissipating phlegm and removing blood stasis, activating collaterals and eliminating stagnation, soothing the liver lactation promoting effect, for acute cream
Adenositis pathogenesis, it is curative for effect.
The resulting Chinese materia medica preparation for treating acute mastitis of the present invention be it is a kind of treat acute mastitis it is long-acting in
Medicine preparation, curative for effect, safety, toxic side effect are small in terms for the treatment of acute mastitis, can reduce clinical patients expense and the course of disease,
And the product type for the treatment of mammary gland disease is increased, it is the good complement of the breast illness dissipating bind serial therapy proliferation of mammary gland, has simultaneously
Good economic value and social value.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
It will be appreciated that the following example is merely to illustrate the present invention, and it is not construed as limiting the scope of the invention.
Embodiment 1
It is a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip 75g, corydalis tuber 75g, bombyx batryticatus 150g are ground into fine powder, cross 80 mesh screens, obtains three taste Chinese herbal medicines
Powder, it is spare.
Step 2, to honeysuckle 150g, Prunella vulgaris 250g, Radix Angelicae Sinensis 150g, radix bupleuri 75g, green peel 75g, dandelion 250g, sweet
Careless 75g, Radix Astragali 250g, dried orange peel 75g, turtle shell 250g, radix scutellariae 75g, great burdock achene 150g, spina gleditsiae 75g, seed of cowherb 150g and road
Road, which leads in ten five tastes Chinese herbal medicine of 150g, adds water to cook extraction 3 times, wherein the amount of water of first time is ten traditional Chinese medicine of the five flavours material amounts
It 8 times, is decocted for the first time to be decocted 2 hours under the conditions of 98 DEG C；Secondary amount of water is 6 times of ten traditional Chinese medicine of the five flavours material amounts,
It is to decoct 1 hour under the conditions of 98 DEG C that second, which decocts,；The amount of water of third time is 6 times of ten traditional Chinese medicine of the five flavours material amounts, third
It is secondary to decoct to be decocted 1 hour under the conditions of 98 DEG C；Filtration, merge 3 filtrates, temperature be 75 DEG C, pressure be -0.06MPa item
It is concentrated under reduced pressure into the clear cream (the detection temperature of relative density is 60~65 DEG C) that relative density is 1.18~1.20 under part, is cooled to
Room temperature obtains liquid extract.
Step 3, adding ethyl alcohol to make alcohol content up to 65% into liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol,
And thick paste (the relative density that relative density is 1.30~1.35 is concentrated under the conditions of temperature is 75 DEG C, pressure is -0.06MPa
Detection temperature be 60 DEG C), be then dried under reduced pressure under the conditions of pressure is -0.06MPa, be ground into fine powder, crossed 80 mesh screens, add
Enter three taste Chinese herbal medicine powders, is uniformly mixed, obtains active pharmaceutical ingredient.
Step 4, it by active pharmaceutical ingredient and pharmaceutically acceptable carrier magnesium stearate compositions, is made for treating acute cream
The capsule of adenositis.
Embodiment 2
It is a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip 25g, corydalis tuber 125g, bombyx batryticatus 50g are ground into fine powder, cross 80 mesh screens, obtains three taste Chinese herbal medicines
Powder, it is spare.
Step 2, to honeysuckle 250g, Prunella vulgaris 350g, Radix Angelicae Sinensis 50g, radix bupleuri 25g, green peel 125g, dandelion 350g, sweet
Careless 25g, Radix Astragali 350g, dried orange peel 25g, turtle shell 150g, radix scutellariae 125g, great burdock achene 50g, spina gleditsiae 125g, seed of cowherb 50g and road
Road, which leads in ten five tastes Chinese herbal medicine of 250g, adds water to cook extraction 3 times, wherein the amount of water of first time is ten traditional Chinese medicine of the five flavours material amounts
It 8 times, is decocted for the first time to be decocted 2.2 hours under the conditions of 95 DEG C；Secondary amount of water is the 6 of ten traditional Chinese medicine of the five flavours material amounts
Times, it is to decoct 1.2 hours under the conditions of 95 DEG C that second, which decocts,；The amount of water of third time is 6 times of ten traditional Chinese medicine of the five flavours material amounts,
Third time decocts to decoct 1.2 hours under the conditions of 95 DEG C；Filtration, merge 3 filtrates, temperature be 70 DEG C, pressure be-
The clear cream that relative density is 1.18~1.20 is concentrated under reduced pressure under the conditions of 0.08MPa, and (the detection temperature of relative density is 60~65
DEG C), it is cooled to room temperature, obtains liquid extract.
Step 3, adding ethyl alcohol to make alcohol content up to 65% into liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol,
And thick paste (the relative density that relative density is 1.30~1.35 is concentrated under the conditions of temperature is 70 DEG C, pressure is -0.08MPa
Detection temperature be 60 DEG C), be then dried under reduced pressure under the conditions of pressure is -0.08MPa, be ground into fine powder, crossed 80 mesh screens, add
Enter three taste Chinese herbal medicine powders, is uniformly mixed, obtains active pharmaceutical ingredient.
Step 4, it combines active pharmaceutical ingredient with pharmaceutically acceptable carrier hydroxypropyl methylcellulose, is made for treating urgency
The Chinese materia medica preparation of property mazoitis.
Embodiment 3
It is a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip 125g, corydalis tuber 25g, bombyx batryticatus 250g are ground into fine powder, cross 80 mesh screens, obtains three taste Chinese herbal medicines
Powder, it is spare.
Step 2, to honeysuckle 50g, Prunella vulgaris 150g, Radix Angelicae Sinensis 250g, radix bupleuri 125g, green peel 25g, dandelion 150g, sweet
Careless 125g, Radix Astragali 150g, dried orange peel 125g, turtle shell 350g, radix scutellariae 25g, great burdock achene 250g, spina gleditsiae 25g, seed of cowherb 250g and
Extraction 3 times is added water to cook in ten five tastes Chinese herbal medicine of Fructus Liquidambaris 50g, wherein the amount of water of first time is ten traditional Chinese medicine of the five flavours material amounts
8 times, decoct for the first time to be decocted 1.8 hours under the conditions of 100 DEG C；Secondary amount of water is ten traditional Chinese medicine of the five flavours material amounts
6 times, it is to decoct 0.8 hour under the conditions of 100 DEG C that second, which decocts,；The amount of water of third time is the 6 of ten traditional Chinese medicine of the five flavours material amounts
Times, third time decocts to decoct 0.8 hour under the conditions of 100 DEG C；Filtration, merge 3 filtrates, temperature be 80 DEG C, pressure be-
The clear cream that relative density is 1.18~1.20 is concentrated under reduced pressure under the conditions of 0.05MPa, and (the detection temperature of relative density is 60~65
DEG C), it is cooled to room temperature, obtains liquid extract.
Step 3, adding ethyl alcohol to make alcohol content up to 65% into liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol,
And thick paste (the relative density that relative density is 1.30~1.35 is concentrated under the conditions of temperature is 80 DEG C, pressure is -0.05MPa
Detection temperature be 60 DEG C), be then dried under reduced pressure under the conditions of pressure is -0.05MPa, be ground into fine powder, crossed 80 mesh screens, add
Enter three taste Chinese herbal medicine powders, is uniformly mixed, obtains active pharmaceutical ingredient.
Step 4, it combines active pharmaceutical ingredient with pharmaceutically acceptable carrier sodium carboxymethyl starch, is made for treating urgency
The Chinese materia medica preparation of property mazoitis.
Embodiment 4
It is a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip 50g, corydalis tuber 100g, bombyx batryticatus 100g are ground into fine powder, cross 80 mesh screens, obtains three taste Chinese herbal medicines
Powder, it is spare.
Step 2, to honeysuckle 200g, Prunella vulgaris 200g, Radix Angelicae Sinensis 200g, radix bupleuri 50g, green peel 100g, dandelion 200g, sweet
Careless 100g, Radix Astragali 300g, dried orange peel 50g, turtle shell 200g, radix scutellariae 100g, great burdock achene 200g, spina gleditsiae 100g, seed of cowherb 200g
It is extracted 3 times with being added water to cook in ten five tastes Chinese herbal medicine of Fructus Liquidambaris 100g, wherein the amount of water of first time is ten traditional Chinese medicine of the five flavours materials
8 times of amount are decocted for the first time to decoct 2 hours under the conditions of 97 DEG C；Secondary amount of water is the 6 of ten traditional Chinese medicine of the five flavours material amounts
Times, it is to decoct 1.0 hours under the conditions of 97 DEG C that second, which decocts,；The amount of water of third time is 6 times of ten traditional Chinese medicine of the five flavours material amounts,
Third time decocts to decoct 1.0 hours under the conditions of 97 DEG C；Filtration, merge 3 filtrates, temperature be 75 DEG C, pressure be-
The clear cream that relative density is 1.18~1.20 is concentrated under reduced pressure under the conditions of 0.07MPa, and (the detection temperature of relative density is 60~65
DEG C), it is cooled to room temperature, obtains liquid extract.
Step 3, adding ethyl alcohol to make alcohol content up to 65% into liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol,
And thick paste (the relative density that relative density is 1.30~1.35 is concentrated under the conditions of temperature is 75 DEG C, pressure is -0.07MPa
Detection temperature be 60 DEG C), be then dried under reduced pressure under the conditions of pressure is -0.07MPa, be ground into fine powder, crossed 80 mesh screens, add
Enter three taste Chinese herbal medicine powders, is uniformly mixed, obtains active pharmaceutical ingredient.
Step 4, it combines active pharmaceutical ingredient with pharmaceutically acceptable carrier dextrin, is made for treating acute mastitis
Chinese materia medica preparation.
Embodiment 5
It is a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, comprising the following steps:
Step 1, edible tulip 100g, corydalis tuber 50g, bombyx batryticatus 200g are ground into fine powder, cross 80 mesh screens, obtains three taste Chinese herbal medicines
Powder, it is spare.
Step 2, to honeysuckle 100g, Prunella vulgaris 300g, Radix Angelicae Sinensis 100g, radix bupleuri 100g, green peel 50g, dandelion 300g, sweet
Careless 50g, Radix Astragali 200g, dried orange peel 100g, turtle shell 300g, radix scutellariae 50g, great burdock achene 100g, spina gleditsiae 50g, seed of cowherb 100g and
Extraction 3 times is added water to cook in ten five tastes Chinese herbal medicine of Fructus Liquidambaris 200g, wherein the amount of water of first time is ten traditional Chinese medicine of the five flavours material amounts
8 times, decoct for the first time to be decocted 2 hours under the conditions of 98 DEG C；Secondary amount of water is the 6 of ten traditional Chinese medicine of the five flavours material amounts
Times, it is to decoct 1 hour under the conditions of 98 DEG C that second, which decocts,；The amount of water of third time is 6 times of ten traditional Chinese medicine of the five flavours material amounts, the
It decocts and is decocted 1 hour under the conditions of 98 DEG C three times；Filtration, merge 3 filtrates, temperature be 70 DEG C, pressure be -0.06MPa item
It is concentrated under reduced pressure into the clear cream (the detection temperature of relative density is 60~65 DEG C) that relative density is 1.18~1.20 under part, is cooled to
Room temperature obtains liquid extract.
Step 3, adding ethyl alcohol to make alcohol content up to 65% into liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol,
And thick paste (the relative density that relative density is 1.30~1.35 is concentrated under the conditions of temperature is 70 DEG C, pressure is -0.06MPa
Detection temperature be 60 DEG C), be then dried under reduced pressure under the conditions of pressure is -0.06MPa, be ground into fine powder, crossed 80 mesh screens, add
Enter three taste Chinese herbal medicine powders, is uniformly mixed, obtains active pharmaceutical ingredient.
Step 4, it by active pharmaceutical ingredient and pharmaceutically acceptable carrier magnesium stearate compositions, is made for treating acute cream
The Chinese materia medica preparation of adenositis.
In the resulting Chinese materia medica preparation for treating acute mastitis of the present invention, the action and efficacy of each raw material is as follows:
Honeysuckle: there is clearing heat and detoxicating, dispelling wind and heat from the body；For carbuncle swells furunculosis, sore throat, erysipelas, toxic-heat and blood stasis, wind-heat sense
It emits, warm disease heating.
Dandelion: there is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia；For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharynx
Bitterly, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Prunella vulgaris: there is clearing liver-fire, improving eyesight, mass dissipating and swelling eliminating；For red eye, swell pain, eyeball night pain, headache and dizziness, scrofula
The effect of scrofula, goiter, acute mastitis, breast illness, breast swell and pain, performance promoting flow of qi and blood circulation resolving hard lump.
Spina gleditsiae: there is detumescence and poison retention, apocenosis, desinsection；For ulcer initial stage or purulence at not bursting；Castor is controlled outside.
Bombyx batryticatus (bran stir-fry): there is Inflammation Zhijing, wind-expelling pain-stopping, reducing phlegm and resolving masses；Phlegm, twitch, children are pressed from both sides for liver wind
It is anxious frightened, tetanus, middle air port, headache due to pathogenic wind-heat, hot eyes pharyngalgia, rubella itch, hair chin or cheek mumps.
Turtle shell (vinegar system): having nourishing and suppressing Yang, brings down a fever except steaming, resolving hard lump；For fever due to yin deficiency, hectic fever due to yin labor heat, the deficiency of Yin
Sun is high, has a dizzy spell, endogenous deficient wind, brothers' Chi Zong, menostasis , Disorder lump in the abdomen, chronic malaria malaria with abdominal mass.
Radix Angelicae Sinensis: there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine effect；For blood deficiency chlorosis, dizziness palpitaition, menstruation is not
It adjusts, amenorrhoea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dry constipation of intestines.
Edible tulip: clearing heat and detoxicating, reducing phlegm and resolving masses；For carbuncle, swelling and furuncle, scrofula subcutaneous nodule, snakebite and bugbite , abdominal mass and lump.
Corydalis tuber: promoting blood circulation, promoting the circulation of qi, analgesic；For chest side of body, epigastric pain, chest impediment and cardialgia, amenorrhea and algomenorrhea, postpartum stasis falls and flutters
Swelling and pain.
Radix bupleuri: there is evacuation to bring down a fever, soothing liver-qi stagnation, lifting disease；For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, the moon
Through uncomfortable, metroptosis, rectal prolapse.
Green peel: having soothing the liver relieving stagnant Qi, and disperse accumulationization is stagnant；For distending pain in the chest and hypochondrium, hernia pain, breast illness, acute mastitis, stagnation of QI due to dyspepsia,
Abdominal distention.
Radix scutellariae: there is heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention；For damp-warm syndrome, summer-heat and damp, chest tightness and emesis, damp and hot feeling of fullness,
Dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, threatened abortion.
Great burdock achene (stir-fry): there is dispelling wind and heat from the body, suitable lung promoting eruption, relieving sore-throat of detoxifying；For anemopyretic cold, coughing with a lot of sputum, morbilli,
Rubeola, abscess of throat, mumps, erysipelas, ulcerative carbuncle pyogenic infections.
Radix Glycyrrhizae: having and invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；It is tired for weakness of the spleen and the stomach
Idle out of strength, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviates toxicity, strong.
Radix Astragali: there is tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing, move stagnation and palsy, pus draining and toxin expelling, sore life
Flesh；For deficiency of vital energy and acking in strength, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy and edema, interior heat disappears
Yearningly, blood deficiency chlorosis, hemiplegia, numbness pain is numb, ulcer is difficult to burst, burst for a long time and does not holds back.
Dried orange peel: having regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm；For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
The seed of cowherb: there is promoting blood circulation and removing obstruction in channels, lower cream detumescence, inducing diuresis for treating strangurtia；For menostasis, dysmenorrhea, agalactia, acute mastitis is swollen
Bitterly, the puckery pain of stranguria.
Fructus Liquidambaris: there is dispelling, collateral-activating, Li Shui, promoting menstruation；For arthralgia, numbness contracture, turgor in water, cream is few, warp
It closes.
Although the present invention is described in detail with a general description of the specific embodiments in this specification,
But on the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.
Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed model
It encloses.
Claims (10)
1. a kind of for treating the Chinese materia medica preparation of acute mastitis, which is characterized in that including following raw material: edible tulip, corydalis tuber, deadlock
Silkworm, honeysuckle, Prunella vulgaris, Radix Angelicae Sinensis, radix bupleuri, green peel, dandelion, Radix Glycyrrhizae, Radix Astragali, dried orange peel, turtle shell, radix scutellariae, great burdock achene, gleditsia sinensis
Thorn, the seed of cowherb and Fructus Liquidambaris.
2. according to claim 1 for treating the Chinese materia medica preparation of acute mastitis, which is characterized in that the Chinese materia medica preparation
For tablet, granule, capsule.
3. according to claim 1 for treating the Chinese materia medica preparation of acute mastitis, which is characterized in that the use of the raw material
Amount are as follows: 25-125 parts of edible tulip, 25-125 parts of corydalis tuber, 50-250 parts of bombyx batryticatus, 50-250 parts of honeysuckle, 150-350 parts of Prunella vulgaris,
50-250 parts of Radix Angelicae Sinensis, 25-125 parts of radix bupleuri, 25-125 parts of green peel, 150-350 parts of dandelion, 25-125 parts of Radix Glycyrrhizae, Radix Astragali 150-
350 parts, 25-125 parts of dried orange peel, 150-350 parts of turtle shell, 25-125 parts of radix scutellariae, 50-250 parts of great burdock achene, 25-125 parts of spina gleditsiae,
50-250 parts and Fructus Liquidambaris 50-250 parts of the seed of cowherb.
4. according to claim 3 for treating the Chinese materia medica preparation of acute mastitis, which is characterized in that the use of the raw material
Amount are as follows: 50-100 parts of edible tulip, 50-100 parts of corydalis tuber, 100-200 parts of bombyx batryticatus, 100-200 parts of honeysuckle, Prunella vulgaris 200-300
Part, 100-200 parts of Radix Angelicae Sinensis, 50-100 parts of radix bupleuri, 50-100 parts of green peel, 200-300 parts of dandelion, 50-100 parts of Radix Glycyrrhizae, Radix Astragali
200-300 parts, 50-100 parts of dried orange peel, 200-300 parts of turtle shell, 50-100 parts of radix scutellariae, 100-200 parts of great burdock achene, spina gleditsiae 50-
100 parts, 100-200 parts of the seed of cowherb and 100-200 parts of Fructus Liquidambaris.
5. according to claim 4 for treating the Chinese materia medica preparation of acute mastitis, which is characterized in that the use of the raw material
Amount are as follows: 75 parts of edible tulip, 75 parts of corydalis tuber, 150 parts of bombyx batryticatus, 150 parts of honeysuckle, 250 parts of Prunella vulgaris, 150 parts of Radix Angelicae Sinensis, radix bupleuri 75
Part, 75 parts of green peel, 250 parts of dandelion, 75 parts of Radix Glycyrrhizae, 250 parts of Radix Astragali, 75 parts of dried orange peel, 250 parts of turtle shell, 75 parts of radix scutellariae, great burdock achene
150 parts, 75 parts of spina gleditsiae, 150 parts of the seed of cowherb and 150 parts of Fructus Liquidambaris.
6. a kind of for treating the preparation method of the Chinese materia medica preparation of acute mastitis, which comprises the following steps:
Step 1, edible tulip, corydalis tuber, bombyx batryticatus are ground into fine powder, are sieved, obtain three taste Chinese herbal medicine powders, it is spare；
Step 2, to honeysuckle, Prunella vulgaris, Radix Angelicae Sinensis, radix bupleuri, green peel, dandelion, Radix Glycyrrhizae, Radix Astragali, dried orange peel, turtle shell, radix scutellariae, fructus arctii
Extraction 3 times is added water to cook in son, ten five tastes Chinese herbal medicine of spina gleditsiae, the seed of cowherb and Fructus Liquidambaris, filtration merges 3 filtrates, depressurizes
It is concentrated into the clear cream that relative density is 1.18~1.20, is cooled to room temperature, obtains liquid extract；
Step 3, add ethyl alcohol to make alcohol content up to 65% in Xiang Suoshu liquid extract, stand 24 hours, filtration, supernatant recycles ethyl alcohol simultaneously
It is concentrated into the thick paste that relative density is 1.30~1.35, is dried under reduced pressure, is ground into fine powder, is sieved, three taste Chinese herbal medicine powders are added, is mixed
It closes uniformly, obtains active pharmaceutical ingredient；
Step 4, it combines the active pharmaceutical ingredient with pharmaceutically acceptable carrier, is made for treating in acute mastitis
Medicine preparation.
7. according to claim 6 for treating the preparation method of the Chinese materia medica preparation of acute mastitis, which is characterized in that step
Described to add water to cook in extraction 3 times in rapid 2, the amount of water of first time is 8 times of ten traditional Chinese medicine of the five flavours material amounts, is decocted for the first time
Temperature be 95~100 DEG C, for the first time decoct time be 1.8~2.2 hours；Secondary amount of water is ten traditional Chinese medicine of the five flavours materials
6 times of quality, second of temperature decocted is 95~100 DEG C, and second of the time decocted is 0.8~1.2 hour；Third time
Amount of water is 6 times of ten traditional Chinese medicine of the five flavours material amounts, and the temperature that third time decocts is 95~100 DEG C, and the time that third time decocts is
0.8~1.2 hour.
8. according to claim 6 for treating the preparation method of the Chinese materia medica preparation of acute mastitis, which is characterized in that step
In rapid 2, the detection temperature of the relative density is 60~65 DEG C.
9. according to claim 6 for treating the preparation method of the Chinese materia medica preparation of acute mastitis, which is characterized in that step
In rapid 2, the temperature of the reduced pressure is 70~80 DEG C, and the pressure of reduced pressure is -0.05~-0.08MPa.
10. according to claim 6 for treating the preparation method of the Chinese materia medica preparation of acute mastitis, which is characterized in that
In step 4, the pharmaceutically acceptable carrier is hydroxypropyl methylcellulose, sodium carboxymethyl starch, dextrin, magnesium stearate.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110170038A (en) * | 2019-06-25 | 2019-08-27 | 郑州秦乐雪健康管理有限公司 | A kind of drug and its preparation method for treating the proliferation of mammary gland |
| CN111514252A (en) * | 2020-06-08 | 2020-08-11 | 首都医科大学附属北京中医医院 | Traditional Chinese medicine composition, medicine, preparation method and application thereof |
-
2019
- 2019-03-28 CN CN201910243636.1A patent/CN109793855A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 李彪等: "《新编中医外科学》", 30 November 1999, 人民军医出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110170038A (en) * | 2019-06-25 | 2019-08-27 | 郑州秦乐雪健康管理有限公司 | A kind of drug and its preparation method for treating the proliferation of mammary gland |
| CN111514252A (en) * | 2020-06-08 | 2020-08-11 | 首都医科大学附属北京中医医院 | Traditional Chinese medicine composition, medicine, preparation method and application thereof |
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