CN103690822B - Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy - Google Patents
Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy Download PDFInfo
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Abstract
The Chinese medicine preparation that the present invention relates to be used for the treatment of constipation in pregnancy, belongs to technical field of traditional Chinese medicines. Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, be characterised in that the component of its bulk drug comprises: hawthorn 15-30 part, selfheal 10-20 part, the membrane of a chicken's gizzard 10-20 part, radix rehmanniae recen 20-30 part, Radix picrorrhizae 6-15 part, honey 20-30 part, Lygodium japonicum 8-16 part, Radix Angelicae Sinensis 15-30 part, root of herbaceous peony 10-20 part, walnut kernel 15-30 part, Semen sesami nigrum 15-30 part, stir-fry rice bud 10-20 part, Inula britannica chinensis 10-20 part, fleece-flower root 10-20 part. Chinese medicine preparation of the present invention is safe, reliable and effective, have no side effect.
Description
Technical field
The Chinese medicine preparation that the present invention relates to be used for the treatment of constipation in pregnancy, belongs to technical field of traditional Chinese medicines.
Background technology
Constipation is pregnant woman's common disease and frequently-occurring disease. Because when conceived, progesterone secretion increases, and makesGastrointestinal smooth muscle is lax, and wriggling slows down, and swill stagnant enteron aisle of a specified duration, causes constipation. After gestationPhase, the fetus and the uterus that day by day increase, compressing rectum also can cause constipation. And gestation is followed constipationIn time, must be noted that to abuse cathartic, otherwise can cause miscarriage, premature labor. Particularly to third trimester of pregnancy,Constipation meeting is more and more serious, usually has not had a motion for several days, and even all fails defecation 1-2 week, therebyCause that pregnant woman suffers from abdominal pain, abdominal distension. Severe patient can cause intestinal obstruction, and concurrent premature labor jeopardizes mother and baby's safety.Once there is patient to excise most of small intestine because constipation, intestinal obstruction cause enteric necrosis in the time of pregnant 38 weeks.When some constipation pregnant woman childbirths, the ight soil being deposited in intestinal tube hinders fetus to decline, and causes that stages of labor prolongsLong even difficult labour.
Gestation constipation patient is comparatively common in clinical. The lighter's abdominal distension, stomachache. Severe patient is because of constipationWith the passing of time affect the gasification function of bladder and may cause AUR. Very person blocks enteron aisle, causesIntestinal obstruction, threat to life.
Summary of the invention
Tcm clinical practice is divided into type of deficiency of both blood and body fluid, large intestine dryness-heat type and lung spleen pregnancy duration dry and hard excrementQi-deficiency type is several.
The present invention aim to provide a kind of for asthenia of pulmonosplenic qi type constipation in pregnancy have safety, reliable,Eutherapeutic Chinese medicine preparation, this Chinese medicine, by selecting suitable raw medicinal material and proportioning thereof, reaches peaceFull object of effectively curing asthenia of pulmonosplenic qi type constipation in pregnancy.
The present invention is achieved by the following technical solutions:
Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, special character is the component bag of its bulk drugDraw together: hawthorn 15-30 part, selfheal 10-20 part, the membrane of a chicken's gizzard 10-20 part, radix rehmanniae recen 20-30Part, Radix picrorrhizae 6-15 part, honey 20-30 part, Lygodium japonicum 8-16 part, Radix Angelicae Sinensis 15-30 part,Root of herbaceous peony 10-20 part, walnut kernel 15-30 part, Semen sesami nigrum 15-30 part, fry rice bud 10-20 part,Inula britannica chinensis 10-20 part, fleece-flower root 10-20 part.
More excellent raw material components is chosen as: 15 parts of hawthorn, 12 parts of selfheals, 15 parts of thes membrane of a chicken's gizzard,20 parts of radix rehmanniae recens, 8 parts of Radix picrorrhizae, 25 parts of honey, 12 parts of Lygodium japonicum, 16 parts of plantain seeds,Old 10 parts of bacterium, 20 parts of Chinese yams, 12 parts of the root of herbaceous peonys, 25 parts of walnut kernel, 30 parts of Semen sesami nigrums, stir-fry rice20 parts of buds, 15 parts of Inula britannica chinensis, 20 parts of the fleece-flowers root.
Hawthorn: containing chlorogenic acid, caffeic acid, crataegolic acid, neat chrysanthemum tartaric acid, Quercetin, ursolic acid,Oleanolic acid, hyperin, epicatechin etc. For rosaceous plant hawthorn, large-fruited Chinese hawthorn or wild mountainThe fruit of short, bristly hair or beard. Appetite-stimulating indigestion-relieving, change stagnant long-pending, the promoting blood circulation to remove blood stasis of disappearing, the promoting the circulation of qi of reducing phlegm. For carnivorous stagnant long-pending,A lump in the abdomen causing distension and pain, abdominal distension ruffian is full, stasis blocking stomachache, phlegm and retained fluid, have loose bowels, discharging fresh blood stool etc.
Selfheal: function cures mainly: relieve inflammation or internal heat, improving eyesight, dissipating bind, detumescence. For red eye, swell pain, orderPearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, swells and ache; Thyroid gland enlargement, scrofula,The proliferation of mammary gland, hypertension, hyperglycaemia, high fat of blood and high blood are sticky.
The membrane of a chicken's gizzard: disappear stagnant, strengthening the spleen and stomach. Control dyspepsia turgor, vomiting gastric disorder causing nausea, rushes down dysentery, infantile malnutrition due to digestive disturbances or intestinalparasites,Quench one's thirst, lose and drown, larynx numbness acute tonsillitis, noma aphtha. Sweet, cold. Return spleen, stomach, small intestine, urinary bladder channel.Food digesting stomach fortifying is aid digestion, arresting seminal emission. Gastric secretion be can promote, gastric acidity and eupepsy improved,Stomach motor function is obviously strengthened, rapid gastric emptying.
Radix rehmanniae recen: clearing heat and promoting fluid enriching yin, nourish blood. Control fever due to yin deficiency, quench one's thirst, spit blood, bleeding from five sense organs or subcutaneous tissue,Metrorrhagia, irregular menstruation, fetal irritability, the moon is hindered constipation.
Radix picrorrhizae: the product of bitter-cold herbs expelling heat eliminating dampness, be apt to remove stomach and intestine damp and hot, be all and control the good of damp-heat dysenteryMedicine. Control infantile malnutrition due to digestive disturbances or intestinalparasites disease, frightened epilepsy, rushes down dysentery, the hot hectic fever due to yin of labor, and spontaneous perspiration, night sweat, spits blood, bleeding from five sense organs or subcutaneous tissue, pinkeye,Hemorrhoid complicated by anal fistula, sore.
Honey: honey has stronger inhibition to gram positive bacterias such as streptococcus, staphylococcus, diphtheriaEffect. Honey has good efficacy to colitis, habitual constipation, and without any side effects. HoneyCan make stomachache and stomach burn feeling disappear, red blood cell and hemoglobin numerical value grow tall. Suffer from gastroduodenalThe people of ulcer, informal dress honey, also has booster action. Harmonizing the spleen and stomach; Relieving spasm to stop pain; Moistening lungCough-relieving; Relax bowel; Moisturizing myogenic; Removing toxic substances. The empty pain of main gastral cavity abdomen; Xeropulmonary cough; Intestines are dryConstipation; Hot eyes aphtha; Unhealing ulcer; Rubella itch; Scald; Brothers are split.
Lygodium japonicum: cold in nature, taste is sweet. Return bladder, small intestinl channel. Eliminating dampness and heat, treating stranguria pain relieving. WithIn heat pouring, sand pouring, blood pouring, cream pouring, Urethra astringent pain.
Radix Angelicae Sinensis: taste is sweet; Pungent; Bitter; Warm in nature. Return liver, the heart, the spleen channel. Antianaemics; Emmenagogue;Anodyne. Cure mainly all cards of the deficiency of blood; Irregular menstruation; Through closing; Dysmenorrhoea; Abdominal mass knot is poly-; Uterine bleeding; EmptyCold stomachache; Impotence numbness; Numbness; Intestines are dry just difficult; Heavy after dysentery characterized by blood in the stool; Ulcer sores; Injury from falling down.
The root of herbaceous peony: enter liver, the spleen channel. Nourishing blood and liver, slow middle pain relieving, astringe yin is received sweat. Control chest abdomen side of body ribPain, rushes down dysentery stomachache, spontaneous sweating, fever due to yin deficiency.
Walnut kernel: sweet, temperature. Return kidney channel, lung, large intestine channel. Kidney tonifying temperature lung, relaxes bowel. InState's medical science thinks that walnut is warm in nature, taste is sweet, nontoxic, have stomach invigorating, enrich blood, moistening lung, the effect such as repose.Shennong's Herbal by walnut classify as clothes of a specified duration make light of one's life by commiting suicide beneficial gas, promote longevity top grade. The Meng the Tang Dynasty numerousIn work " dietetic materia medica ", describe, eating walnut kernel can whet the appetite, and logical profit blood vessels, make kindred exquisiteness.In the works such as Song dynasty Liu Han " Kaibao Bencao ", describe, " order of food is fertile strong, profit flesh, black palpus for walnut kernelSend out, eat sharp little water more, go five hemorrhoid. " Ming Dynasty's Li Shizhen (1518-1593 A.D.) work Compendium of Material Medica description, walnut kernel has" the beneficial gate of vitality, locates three warmers for benefiting qi and nourishing blood, moistening dryness and resolving phlegm, and warm lung ease constipation, controls the cold of insufficiency type and breath with cough, waistPin heavily aches, trusted subordinate's colic, bloody flux intestines wind " etc. effect.
Semen sesami nigrum: sweet, flat. Return liver, kidney, large intestine channel. Filling liver kidney, benefiting essence-blood, ease constipation is dry.For dizzy, Hiccough and deaf, poliosis, post disease alopecia, the dry constipation of intestines. Traditional Chinese medicineTheory thinks, Semen sesami nigrum has filling liver kidney, moisturizing viscera, beneficial strength, longue meat, fills out the work of brainsWith, can be used for treating dizzy, poliosis due to liver kidney asthenia of essence and blood, alopecia, soreness and weakness of waist and knees,Limbs fatigue, walk with difficulty, the illness such as deficient five internal organs, skin are dryly sent out withered, the dry constipation of intestines, send out crowEffect of beauty treatment aspect, celebrated especially.
Fry rice bud: sweet, temperature. Return spleen, stomach warp. With in help digestion, spleen benefiting and stimulating the appetite. For dyspepsia notDisappear, abdominal distension halitosis, weakness of the spleen and the stomach, not hungry food is few. Frying rice bud relatively helps digestion. Few for not hungry food.The kind eliminate indigestion of burnt rice bud is stagnant. Do not disappear for stagnant.
Inula britannica chinensis: bitter; Pungent; Salty; Tepor. Return lung; Stomach; Large intestine channel. Sending down abnormally ascending, dissolving phlegm,Row water, preventing or arresting vomiting. For cough due to wind-cold evil, phlegm and retained fluid is held knot, and chest diaphragm ruffian is full, dyspnea and cough with excessive sputum, vomitingGas, epigastric fullness and rigidity.
The fleece-flower root: hardship; Sweet; Puckery; Slightly warm in nature, returns liver, kidney channel. Enrich and benefit essence and blood; Raw using: separatePoison, preventing malaria, relaxes bowel. [curing mainly] deficiency of blood Light-headedness; Palpitaition; Insomnia; The deficiency of liver-yin and kidney-yin itSoreness and weakness of waist and knees; Poliosis; Tinnitus; Seminal emission; The dry constipation of intestines; Chronic malaria body void; Rubella itch;Sore carbuncle; Scrofula; Hemorrhoid.
The control of the selected material composition of the present invention and consumption effectively impels asthenia of pulmonosplenic qi type gestationPhase constipation, by cooperatively interacting between various compositions, reaches right by promoting lung qi and harmonizing the spleen and stomachThe object that the symptom of asthenia of pulmonosplenic qi type constipation in pregnancy rapidly, is effectively alleviated and treated.
Below in conjunction with clinical trial data declaration beneficial effect of the present invention:
1, physical data
Inventor has collected altogether 75 routine constipations in pregnancy between year October in June, 2011 to 2012Out-patient, in age 24-35 year, be divided at random: treatment group 50 examples, control group 25 examples.Two groups of patients' state of an illness data, without significant difference, has comparativity.
2, test method
2.1, control group 25 examples are only taken placebo, and 300-500ml keeps the skin wet every day in addition;
2.2, the patent medicine that treatment group 50 example adopts oral the present invention to press, the morning, noon and afternoon respectively once, the course for the treatment ofTwo weeks.
3, criterion of therapeutical effect and treatment results
3.1, criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappear, and laboratory examination is normal. Take a turn for the better: clinical symptom relief,Laboratory examination improves or is normal. Invalid: clinical symptoms are without being clearly better or increasing the weight of.
3.2, treatment statistics is in table 1
The Comparison of therapeutic of table 1 treatment group and control group
Group | Case load | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
Treatment group | 50 | 38(76%) | 10(20%) | 2(4%) | 96% |
Control group | 25 | 5(20%) | 5(20%) | 15(60%) | 40% |
Show by above-mentioned experimental data, it is pregnant that the medicine that the present invention makes can be pacified effective treatment entirelyThe phase constipation of being pregnent.
Detailed description of the invention
In order to understand better and to implement the present invention, below in conjunction with detailed description of the invention, be used for to thisBright formation is further described.
Embodiment 1
Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, the component of its bulk drug comprises: 15 grams of hawthorn,10 grams of selfheals, 10 grams of thes membrane of a chicken's gizzard, 20 grams of radix rehmanniae recens, 6 grams of Radix picrorrhizae, 20 grams of honey,8 grams of Lygodium japonicum, 15 grams of Radix Angelicae Sinensis, 10 grams of the root of herbaceous peonys, 15 grams of walnut kernel, 15 grams of Semen sesami nigrums, stir-fry10 grams of rice buds, 10 grams of Inula britannica chinensis, 10 grams of the fleece-flowers root.
Embodiment 2
Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, the component of bulk drug comprises: 30 grams of hawthorn,20 grams of selfheals, 20 grams of thes membrane of a chicken's gizzard, 30 grams of radix rehmanniae recens, 15 grams of Radix picrorrhizae, 30 grams of honey,16 grams of Lygodium japonicum, 30 grams of Radix Angelicae Sinensis, 20 grams of the root of herbaceous peonys, 30 grams of walnut kernel, 30 grams of Semen sesami nigrums, stir-fry20 grams of rice buds, 20 grams of Inula britannica chinensis, 20 grams of the fleece-flowers root.
Embodiment 3
Be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, the component of its bulk drug comprises: 20 grams of hawthorn,20 grams of selfheals, 15 grams of thes membrane of a chicken's gizzard, 25 grams of radix rehmanniae recens, 10 grams of Radix picrorrhizae, 25 grams of honey,10 grams of Lygodium japonicum, 20 grams of Radix Angelicae Sinensis, 15 grams of the root of herbaceous peonys, 20 grams of walnut kernel, 25 grams of Semen sesami nigrums, stir-fry15 grams of rice buds, 15 grams of Inula britannica chinensis, 15 grams of the fleece-flowers root.
The Chinese medicine preparation of above embodiment, can adopt the conventional method of Chinese medicine preparation to be prepared into anyConventional oral preparations, comprises powder, tablet, capsule, pill etc.
Claims (1)
1. be used for the treatment of the Chinese medicine preparation of constipation in pregnancy, be characterised in that the component of its bulk drug is: hawthorn 15-30 part, selfheal 10-20 part, the membrane of a chicken's gizzard 10-20 part, radix rehmanniae recen 20-30 part, Radix picrorrhizae 6-15 part, honey 20-30 part, Lygodium japonicum 8-16 part, Radix Angelicae Sinensis 15-30 part, root of herbaceous peony 10-20 part, walnut kernel 15-30 part, Semen sesami nigrum 15-30 part, stir-fry rice bud 10-20 part, Inula britannica chinensis 10-20 part, fleece-flower root 10-20 part.
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CN102008662B (en) * | 2010-04-27 | 2012-05-23 | 泰一和浦(北京)中医药研究院有限公司 | Traditional Chinese medicine composition for treating constipation and preparation method thereof |
CN102266523A (en) * | 2011-07-08 | 2011-12-07 | 刘学勤 | Traditional Chinese medicine for treating gestational dry stool |
CN102552752A (en) * | 2011-12-30 | 2012-07-11 | 栾清杨 | Intestine-moistening and dryness-moistening drinking tea for treating constipation |
CN102846819A (en) * | 2012-08-06 | 2013-01-02 | 吴金霞 | Chinese medicinal preparation for treating gestational coprostasis |
CN102895400B (en) * | 2012-10-16 | 2013-12-18 | 祝雨婷 | Traditional Chinese medicine decoction for treatment of diabetic constipation of elderly |
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Effective date of registration: 20170502 Address after: 226500, No. 999, Wanshou South Road, Rugao City, Jiangsu province (room 3A08-26, building 8, hi tech Zone, Nantong) Patentee after: Jiangsu hundred sword Pharmaceutical Technology Co., Ltd. Address before: 241000 Anhui city of Wuhu province Liantang village Jinghu District Ruifeng garden B Building No. 07 Patentee before: Wuhu Yueruisi Information Consulting Co., Ltd. |