CN104398618A - Traditional Chinese medicine composition for treating abnormal menstruation - Google Patents

Traditional Chinese medicine composition for treating abnormal menstruation Download PDF

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Publication number
CN104398618A
CN104398618A CN201410603383.1A CN201410603383A CN104398618A CN 104398618 A CN104398618 A CN 104398618A CN 201410603383 A CN201410603383 A CN 201410603383A CN 104398618 A CN104398618 A CN 104398618A
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parts
chinese medicine
medicine composition
menoxenia
treatment
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潘高峰
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HUZHOU DAOCHANGXIANG ASSET MANAGEMENT Co Ltd
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HUZHOU DAOCHANGXIANG ASSET MANAGEMENT Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a traditional Chinese medicine composition for treating abnormal menstruation. The traditional Chinese medicine composition comprises, by weight, 8-12 parts of fiddleleaf aster, 18-28 parts of motherwort, 6-10 parts of Ixora chinensis Lam., 6-10 parts of Saururuschinensis(Lour.)Baill. and 2-6 parts of ricepaperplant pith medulla tetrapanacis. The traditional Chinese medicines of the traditional Chinese medicine composition supplement each other, produce synergism and have effects of moving qi and dissipating stasis, supporting body resistance, invigorating blood circulation and freeing channel, promoting blood circulation to remove blood stasis, relieving exterior syndrome and enriching blood, and tonifying kidney and invigorating spleen. The traditional Chinese medicine composition has substantial curative effects on a plurality of gynecological diseases such as endocrine dyscrasia-caused abnormal menstruation, hyperplasia of mammary glands, dysmenorrhoea and amenorrhoea, produces effects fast, has a short treatment course and a high cure rate, has obvious curative effects on abnormal menstruation, has no toxic or side effect and is safe and reliable.

Description

A kind of Chinese medicine composition for the treatment of menoxenia
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition can treating menoxenia.
Background technology
Menstruation is the physiological phenomenon of female normal, is the symbol of fertility.Menoxenia also claims menoxenia, is gynecological's common disease, shows as the exception of menstrual cycle or amount of bleeding, can accompany that the moon is premenstrual, menstrual period time stomachache and General Symptoms.The cause of disease may be organic disease or malfunction.Such as mood disorders, cold stimulation, go on a diet, all can cause menoxenia addicted to tobacco and wine.If menstruation is lost in normal manner, then it is menoxenia.If wrong treatment is controlled in delay treatment or mistake, can cause anemia, amenorrhea, metrorrhagia, sterility and infertility etc., severe patient can affect women's physical and mental health.
The fundamental symptoms of menoxenia is: 1. advanced menstruation.Menstruation refers to that menstrual cycle is normal at ordinary times, occurs that suddenly menstrual cycle shortens, is shorter than 21 days in advance, and occurs more than 2 cycles continuously, but menstrual blood volume is normal.Belong to ovulation type anovulatory dysfunctional uterine hemorrhage basal body temperature two-phase, follicular phase is short, only 7 ~ 8 days, or is shorter than 10 days luteal phase, or body temperature rising is less than 0.5 DEG C.2 menstrual period postponed.Menstruation rule at ordinary times, postponed menstruation more than 7 days, even 40 ~ 50 days a line, and there are more than two menstrual cycle continuously, but menstrual blood volume is normal.Have ovulation person, basal body temperature two-phase, but follicular phase is long, high-temperature-phase is on the low side; Anovulation person, basal body temperature is single-phase.3. menostaxis.Menstrual cycle is normal, normal through measuring, but menostaxis, menstrual period, even 2 weeks sides were clean more than more than 7 days.Have inflammation person's lower abdomen pain at ordinary times, menstrual period increase the weight of, and leucorrhea amount is many at ordinary times, and yellow skin or HUANGBAI(sic), matter is thick, have taste.The infull person of atrophy of corpus iuteum is simultaneously with menorrhagia; Endometrium reparation prolongs elder at menorrhea after date, still has a small amount of persistence vaginal hemorrhage.4. menoxenia.Menstruation successively irregularly, menstruation in advance or postpone, cycle or be shorter than 21 days, or be longer than 35 days.5. Intermenstrual bleeding (also known as intermenstrual bleeding, ovulatory hemorrhage).What refer to occur in the middle of twice normal menstrual cycle of rule is hemorrhage, is due to the of short duration decline of estrogen level, makes that endometrium loses the support of hormone and that the endometrium that causes comes off and causes is hemorrhage.
At present, clinical treatment menoxenia medicament categories is various, and also have and adopt medicine for external use treatment, western medicine mainly uses estrogen, progestogen to adjust menstrual cycle, oral clomiphene induced ovulation, but curative effect differs and side effect is large; But mostly have that therapeutic effect is undesirable, the course for the treatment of is longer, cost is higher, obstinate, the problem such as slowly of producing effects.During two or more drug combination, if their action direction is consistent, reaches the effect strengthened each other and be called synergism.The intensity difference presented according to synergism can be divided into summation action and potentiation.When summation action is drug combination, its total effect equals the summation of each prescription used time effect.When potentiation is drug combination, its total effect exceedes the summation of each prescription used time effect.During drug combination, if their effect is contrary, reaches the effect weakening each other or disappear and be called antagonism.In Chinese medicine composition provided by the invention, the long-term practice through inventor draws, treatment by Chinese herbs menoxenia has better effect, obtains good effect.Each medicine supplements and complements each other, and mutually at synergism, plays circulation of qi promoting dissipating blood stasis altogether, the body resistance strengthening and constitution consolidating, promoting blood circulation to restore menstrual flow, blood circulation promoting and blood stasis dispelling, induce sweat and enrich blood, benefiting QI and nourishing blood, effect of kidney and spleen invigorating, have significant curative effect to various gynecological diseases such as the menoxenia caused by endocrine disturbance, cyclomastopathy, dysmenorrhea, amenorrheas, effect is rapidly, rapid-action, short treating period, cure rate is high, has obvious curative effects to menoxenia, have no side effect, safe and reliable.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of menoxenia, its good effect has no side effect.
Technical scheme of the present invention is as follows:
Treat a Chinese medicine composition for menoxenia, it is characterized in that, comprise the component of following weight portion: Aster panduratus Nees ex Walper 8-12 part, Herba Leonuri 18-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6-10 part, BAIJIEOU 6-10 part, Medulla Tetrapanacis 2-6 part.
The component of following weight portion is preferably included: Aster panduratus Nees ex Walper 8 parts, Herba Leonuri 18 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6 parts, BAIJIEOU 6 parts, Medulla Tetrapanacis 2 parts in the Chinese medicine composition of above-mentioned treatment menoxenia.
The component of following weight portion is preferably included: Aster panduratus Nees ex Walper 12 parts, Herba Leonuri 28 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 10 parts, BAIJIEOU 10 parts, Medulla Tetrapanacis 6 parts in the Chinese medicine composition of above-mentioned treatment menoxenia.
The component of following weight portion is preferably included: 10 parts, limit, hilllock, Herba Leonuri 24 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8 parts, BAIJIEOU 8 parts, Medulla Tetrapanacis 4 parts in the Chinese medicine composition of above-mentioned treatment menoxenia.
The component of following weight portion is preferably included: limit, hilllock 10-12 part, Herba Leonuri 22-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8-10 part, BAIJIEOU 8-10 part, Medulla Tetrapanacis 4-6 part in the Chinese medicine composition of above-mentioned treatment menoxenia.
Present invention also offers above-mentioned a kind of preparation method for the treatment of the Chinese medicine composition of menoxenia, comprise the steps: to get Aster panduratus Nees ex Walper 8-12 part in prescription, Herba Leonuri 18-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6-10 part, BAIJIEOU 6-10 part, Medulla Tetrapanacis 2-6 part, add 12-16 times amount water boiling and extraction 3-5 time, each 1-1.5 hour, merge extractive liquid, filter, after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, the ultrafiltration of 100KDa ultrafilter membrane, and ultrafiltrate is concentrated into relatively for density is the thick paste of 1.10-1.35, drying under reduced pressure, obtained described Chinese medicine composition.
Present invention also offers above-mentioned a kind of preparation for the treatment of the Chinese medicine composition of menoxenia, it is characterized in that, described preparation is powder, pill, tablet, capsule, granule or oral liquid.
Present invention also offers the above-mentioned a kind of application of Chinese medicine composition in preparation treatment menoxenia product for the treatment of menoxenia.
In the present invention, the pharmacological property of each raw material is as follows:
Aster panduratus Nees ex Walper: meridian distribution of property and flavor: bitter, pungent, temperature.Warming spleen and stomach for dispelling cold, cough-relieving, pain relieving.For phlegm dyspnea of coughing, chronic gastralgia, has loose bowels.Effect: promoting the circulation of QI to relieve pain, relieving cough and asthma.Cure mainly: by uncomfortable in chest, hypochondriac pain, abdominal distention, the colic of cold type stomachache controlled caused by the cold strongly fragrant stagnation of QI, the diseases such as dysmenorrhea.With control accumulation and obstruction of sputum, dyspnea and cough due to adverse raising of QI, septum pectorale full vexed, thin sputum is thin, the partially cold person of cough with asthma.
Elixir of life flower: be also called Flos lilli concoloris Salisb., Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), be namely commonly called as the evergreen shrubs of the short elixir of life.Meridian distribution of property and flavor: flower: sweet light, cool.Root: bitter, micro-puckery, cool.Flower: clearing away heat and cooling blood, eliminating stasis to stop pain.Root: clearing away heat and cooling blood, promoting blood circulation and stopping pain.Function cures mainly: flower: hypertension, menoxenia, amenorrhea, traumatic injury, skin infection furuncle and phyma.Root: cough, spitting of blood, rheumatic arthritis, stomachache, women's amenorrhea, skin infection swells and ache, traumatic injury.
Herba Leonuri: have another name called: Tui, motherwort, Herba Leonuri, nine Rhizoma Paridis, Muscovitum grass, the gloomy base of a fruit.Meridian distribution of property and flavor: acrid in the mouth; Bitter; Property micro-enter, enter the heart, liver, urinary bladder channel.Function cures mainly: invigorate blood circulation, blood stasis dispelling, regulating menstruation, and disappear water.Control menoxenia, vaginal bleeding during pregnancy is had difficult labour, and retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Promoting tissue regeneration by removing blood stasis, can be used for traumatic injury again, also has certain curative effect for women by damp and hot pelvic inflammation.
BAIJIEOU: have another name called that water Semen Arecae, SANYE are white, Ji Taicao, smelly old, the slow wind of chicken, side of a pond Rhizoma Nelumbinis.Meridian distribution of property and flavor: pungent, gas is smelly, warm in nature, nontoxic, enters Liver and kidney warp.Function cures mainly: pathogenic wind expelling cold expelling for oral administration dries pain relieving; Leaf externally applied toxicity removing.Cure mainly beriberi, freight, flank pain, heel pain is soft, the kidney-wind syndrome, hernia, married woman leucorrhea; Leaf external treatment skin noxious dampness, carbuncle of yin nature knot poison.
Medulla Tetrapanacis: another name bandit takes off, from southern, Huo Tuo, lean on business etc., is the stem pith of Araliaceae rice-paper plant.Meridian distribution of property and flavor: sweet; Light; Be slightly cold, enter lung, stomach warp.Function cures mainly: wet clearly diuretic; Lactogenesis.The puckery pain of main stranguria; Dysuria; Edema; Jaundice; Damp-warm diseases; Oliguria with reddish urine; Puerperal, breast was few; Amenorrhea; Leukorrhagia.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia.Except the edema difficulty in urination, control five types of stranguria.
The present invention adopts limit, hilllock, Herba Leonuri, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), BAIJIEOU, the multiple medical material scientific combination of Medulla Tetrapanacis, each medicine supplements and complements each other, mutually at synergism, gather circulation of qi promoting dissipating blood stasis altogether, the body resistance strengthening and constitution consolidating, promoting blood circulation to restore menstrual flow, blood circulation promoting and blood stasis dispelling, induce sweat and enrich blood, benefiting QI and nourishing blood, effect of kidney and spleen invigorating, to various gynecological diseases such as the menoxenia caused by endocrine disturbance, cyclomastopathy, dysmenorrhea, amenorrheas, there is significant effect, effect is rapidly, rapid-action, short treating period, cure rate is high, there is obvious curative effects to menoxenia, have no side effect, safe and reliable.Have the effect of Synergistic between Aster panduratus Nees ex Walper, Herba Leonuri, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), BAIJIEOU, Medulla Tetrapanacis five kinds of medicines, lack wherein a herb arbitrarily, its curative effect all has obvious reduction, therefore complements each other between this Chinese medicine of the five flavours, indispensable.
Detailed description of the invention
Below in conjunction with embodiment, further illustrate content of the present invention.Should be appreciated that enforcement of the present invention is not limited to the following examples, any pro forma accommodation make the present invention and/or change all will fall into scope.
In the present invention, if not refer in particular to, all parts, percentage ratio are unit of weight, and all equipment and raw material etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
Embodiment 1: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: Aster panduratus Nees ex Walper 8g, Herba Leonuri 18g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6g, BAIJIEOU 6g, Medulla Tetrapanacis 2g.
Embodiment 2: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: Aster panduratus Nees ex Walper 9g, Herba Leonuri 22g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 7g, BAIJIEOU 7g, Medulla Tetrapanacis 3g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 10g, Herba Leonuri 24g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8g, BAIJIEOU 8g, Medulla Tetrapanacis 4g.
Embodiment 4: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 11g, Herba Leonuri 26g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 9g, BAIJIEOU 9g, Medulla Tetrapanacis 5g.
Embodiment 5: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: Aster panduratus Nees ex Walper 12g, Herba Leonuri 28g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 10g, BAIJIEOU 10g, Medulla Tetrapanacis 6g.
Comparative example 1: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: Herba Leonuri 24g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8g, BAIJIEOU 8g, Medulla Tetrapanacis 4g.
Comparative example 2: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 10g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8g, BAIJIEOU 8g, Medulla Tetrapanacis 4g.
Comparative example 3: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 10g, Herba Leonuri 24g, BAIJIEOU 8g, Medulla Tetrapanacis 4g.
Comparative example 4: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 10g, Herba Leonuri 24g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8g, Medulla Tetrapanacis 4g.
Comparative example 5: a kind of Chinese medicine composition for the treatment of menoxenia, comprises following component: limit, hilllock 10g, Herba Leonuri 24g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8g, BAIJIEOU 8g.
Wherein the preparation method of embodiment 1-5 and comparative example 1-5 includes following steps: get the Aster panduratus Nees ex Walper of recipe quantity, Herba Leonuri, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), BAIJIEOU, Medulla Tetrapanacis, add 12-16 times amount water boiling and extraction 3-5 time, each 1-1.5 hour, merge extractive liquid, filter, after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, the ultrafiltration of 100KDa ultrafilter membrane, and ultrafiltrate is concentrated into relatively for density is the thick paste of 1.10-1.35, drying under reduced pressure, obtained described Chinese medicine composition.
The Chinese medicine composition of the chronic menoxenia for the treatment of of the present invention, clinical efficacy is summed up:
One, general data: this Chinese medicine composition be applied to clinical observation case 480 example, age 18-45 year.The shortest person of the course of disease 3 months, most elder reaches 2 years.
Two, diagnostic criteria:
(1), there are 3 above persons of menstrual cycle continuously in preceeded menorrhea: menstrual cycle shifts to an earlier date more than 7 days;
(2), there are 3 above persons of menstrual cycle continuously in delayed menstrual cycle: menstrual cycle delays more than 7 days;
(3) irregular menstrual period: time during menstruation or in advance or delay more than 7 days but be no more than 2 weeks, continuous appearance 3 above persons of menstrual cycle;
(4) menorrhagia: menstrual cycle is normal, and through amount showed increased more in the past, or there are two above persons of menstrual cycle through amount continuously more than l00ml;
(5) hypomenorrhea: menstrual cycle is normal, and through measuring obvious minimizing. or shorten menstrual period less than 2 days, be also less than through amount normal, occur two cycle above persons continuously;
(6) menostaxis: menstrual cycle and normal through measuring, the time of passing through was more than more than 7 days but be less than 2 weeks, occurred two above persons of menstrual cycle continuously.
Three, usage and dosage: potion on the one, decocting twice extracting juice is about 200ml, point morning, late twice decoction being taken warmly.It within six days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect:
(1) cure: menstrual blood loss, menstrual cycle recover normal, after drug withdrawal, 6 menstrual cycle are without repeatedly;
(2) effective: menstrual blood loss, menstrual cycle are normal, and after drug withdrawal, 6 menstrual cycle do not recur;
(3) invalid: menstrual blood loss, menstrual cycle are not improved.
Five, experiment grouping: 480 clinical patients are divided into 6 groups at random, often organize 80 people, take 6 kinds of Chinese medicine compositions in experimental example 3 and comparative example 1-5 respectively.Consumption and usage: take each raw material by the weight portion of constitutive material, decoct 20-30 minute, stir, cooling and drinkable, every day, potion, one month was a course for the treatment of.
Six, therapeutic effect: in this clinical observation case, takes medicine 1-8 the course for the treatment of, and institute's curative effect that obtains is in table 1.
The effect of table 1. traditional Chinese medicine composition for treating menoxenia
Experimental result shows: embodiment 3 and comparative example 1-5 all have certain therapeutic effect for menoxenia, and cure rate can reach more than 45% respectively, and total effective rate can reach more than 80% respectively; But, the combination of Aster panduratus Nees ex Walper, Herba Leonuri, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), BAIJIEOU, Medulla Tetrapanacis five kinds of Chinese medicine compositions in embodiment 3, make its therapeutic effect than only there being the therapeutic effect tool of the combination of compositions of four kinds of Chinese medicines to be significantly increased in comparative example 1-5, cure rate can reach 98.75%, and total effective rate can reach 100%.Visible, have the effect of Synergistic between Aster panduratus Nees ex Walper, Herba Leonuri, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), BAIJIEOU, Medulla Tetrapanacis five kinds of medicines, lack wherein a herb arbitrarily, its curative effect all has obvious reduction, therefore complements each other between this Chinese medicine of the five flavours, indispensable.There is not toxic and side effects in treatments period.
Seven, model case:
Case 1: Lee, female, 42 years old, menoxenia, every month is through postponing one week or longer, Hypomenorrhea, there is kermesinus clot, with the symptom such as dizzy, nervous, take Chinese medicine composition of the present invention, every day potion, after taking two courses for the treatment of of embodiment 3 Chinese medicine, menstruation recovers normal substantially, without the symptom such as dizzy, nervous, after continuing to take two courses for the treatment of, menstruation recovery is normal.
Case 2: Wu, female, 31 years old, long-term menoxenia, monthly comes through postponing, Hypomenorrhea, menstrual phase is long, with symptoms such as soreness of waist and knee, dizziness, anemias, takes Chinese medicine composition of the present invention, every day potion, after taking a course for the treatment of of embodiment 3 Chinese medicine, menstruation as scheduled, but Hypomenorrhea, after continuing to take two courses for the treatment of, the eumenorrhea.
Case 3: Wang, female, 37 years old, more than ten skies were postponed in each menstruation, and menstrual period are long, and color secretly has clot, and companion's pain in the lumbar region lower limb is soft, few distention and fullness in the abdomen, Breast pain, puffiness of the face and limbs, and tongue wets in vain, and stringy pulse is weak, is diagnosed as menoxenia; Take Chinese medicine composition of the present invention, every day potion, after taking two courses for the treatment of, menstrual cycle recovers normal, and amount is many, has clot, and after continuing to take two courses for the treatment of, menstrual period, normal through measuring, recovery from illness, follows up a case by regular visits to after half a year without recurrence.

Claims (8)

1. treat a Chinese medicine composition for menoxenia, it is characterized in that, comprise the component of following weight portion: Aster panduratus Nees ex Walper 8-12 part, Herba Leonuri 18-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6-10 part, BAIJIEOU 6-10 part, Medulla Tetrapanacis 2-6 part.
2. a kind of Chinese medicine composition for the treatment of menoxenia according to claim 1, is characterized in that, comprise the component of following weight portion: Aster panduratus Nees ex Walper 8 parts, Herba Leonuri 18 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6 parts, BAIJIEOU 6 parts, Medulla Tetrapanacis 2 parts.
3. a kind of Chinese medicine composition for the treatment of menoxenia according to claim 1, is characterized in that, comprise the component of following weight portion: Aster panduratus Nees ex Walper 12 parts, Herba Leonuri 28 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 10 parts, BAIJIEOU 10 parts, Medulla Tetrapanacis 6 parts.
4. a kind of Chinese medicine composition for the treatment of menoxenia according to claim 1, is characterized in that, comprise the component of following weight portion: 10 parts, limit, hilllock, Herba Leonuri 24 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8 parts, BAIJIEOU 8 parts, Medulla Tetrapanacis 4 parts.
5. a kind of Chinese medicine composition for the treatment of menoxenia according to claim 1, is characterized in that, comprise the component of following weight portion: limit, hilllock 10-12 part, Herba Leonuri 22-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 8-10 part, BAIJIEOU 8-10 part, Medulla Tetrapanacis 4-6 part.
6. prepare the method for Chinese medicine composition described in claim 1 for one kind, it is characterized in that, comprise the following steps: get Aster panduratus Nees ex Walper 8-12 part in formula, Herba Leonuri 18-28 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 6-10 part, BAIJIEOU 6-10 part, Medulla Tetrapanacis 2-6 part, adds 12-16 times amount water boiling and extraction 3-5 time, each 1-1.5 hour, merge extractive liquid, filters, and after concentrating under reduced pressure, concentrated solution adopts suitable quantity of water dilution, the ultrafiltration of 100KDa ultrafilter membrane, ultrafiltrate is concentrated into relatively for density is the thick paste of 1.10-1.35, drying under reduced pressure, obtained described Chinese medicine composition.
7. contain a preparation for Chinese medicine composition as claimed in claim 1, it is characterized in that, described preparation is powder, pill, tablet, capsule, granule or oral liquid.
8. the application of Chinese medicine composition in preparation treatment menoxenia product as claimed in claim 1.
CN201410603383.1A 2014-10-30 2014-10-30 Traditional Chinese medicine composition for treating abnormal menstruation Pending CN104398618A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105935402A (en) * 2016-05-06 2016-09-14 许美凤 Traditional Chinese medicinal composition for treating abnormal menstruation

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