CN103751482B - A kind of medicine and preparation method being used for the treatment of puerperal abdonimal pain - Google Patents
A kind of medicine and preparation method being used for the treatment of puerperal abdonimal pain Download PDFInfo
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- CN103751482B CN103751482B CN201410063001.0A CN201410063001A CN103751482B CN 103751482 B CN103751482 B CN 103751482B CN 201410063001 A CN201410063001 A CN 201410063001A CN 103751482 B CN103751482 B CN 103751482B
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- 208000002193 Pain Diseases 0.000 title claims abstract description 102
- 230000036407 pain Effects 0.000 title claims abstract description 102
- 239000003814 drugs Substances 0.000 title claims abstract description 46
- 238000002360 preparation methods Methods 0.000 title claims abstract description 8
- 239000004615 ingredient Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 241000717739 Boswellia sacra Species 0.000 claims abstract description 10
- 241000466766 Celastrus gemmatus Species 0.000 claims abstract description 9
- 240000000161 Lagerstroemia indica Species 0.000 claims abstract description 9
- 239000004863 Frankincense Substances 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 15
- 238000004140 cleaning Methods 0.000 claims description 13
- 239000012153 distilled water Substances 0.000 claims description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
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- 231100000486 side effect Toxicity 0.000 abstract description 4
- 230000000146 antalgic Effects 0.000 abstract description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N p-acetaminophenol Chemical compound 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Abstract
The invention discloses a kind of medicine and the preparation method that are used for the treatment of puerperal abdonimal pain, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Rhizoma Lycopi Lucidi, gristle wind, Olibanum, Celastrus gemmatus Loes., Radix seu Caulis Kadsurae Heteroclitae, Herba Lycopi, Fructus Crataegi, Pollen Typhae, Radix Ribis davidii, Herba Rubi parvifolii, Herba leonuri pseudoma cranthi, Herba artemisiae lactiflorae, Radix Lagerstroemia indica L., Rhizoma Dioscoreae Cirrhosae and Cortex Euonymi phellomanis; Medicine of the present invention have enrich blood invigorate blood circulation, effect of antalgic, circulation of qi promoting dissipating blood stasis, expelling wind and removing dampness, to the abdominal pain symptom caused puerperal, there is significant curative effect, safe and reliable, without any side effects, can suppress puerperal abdonimal pain, promote WomanHealth and have positive effect, clinical trial shows, to the total effective rate of puerperal abdonimal pain patient treatment up to 96.9%, clinic wide popularization and application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and the preparation method that are used for the treatment of puerperal abdonimal pain.
Background technology
After parturient childbirth, lower abdomen pain person, is called " puerperal abdonimal pain ", also known as " after-pains ".Primary disease is equivalent to the stomachache that the puerperal uterine contraction pain of western medicine and puerperal infection cause.
In general, cause the reason of women's lower abdominal pain, the hypogastralgia that the pain that menstrual cycle can be divided into be correlated with cause and non-menstrual cycle cause.Primipara because of uterine fibroid comparatively tight, uterine contraction is very strong, easily restores, and it is also shorter to restore required time, and pain is not obvious; Multipara due to multiple pregnancies, uterus muscle fiber repeatedly tractive, it is more difficult to restore, and pain time extends relatively, and pain also comparatively primipara is more acutely.
Puerperal abdonimal pain comprises stomachache and lower abdominal pain, the most common with lower abdomen pain, mostly due to blood stasis, asthenia of qi and blood, or caused by being affected by the cold, stagnate based on postnatal blood stasis or air-cooled name " after-pains " of holding blood stasis under the arm, lower abdomen can touch lump, has obvious tenderness, often double see lochia not freely or not under, distension and fullness of the chest and abdomen, arteries and veins many strings Grating is strong, has difference that is partially cold, partial heat.Every easily affection of exogenous wind-cold of asthenia of qi and blood, common stomachache happiness heat is pressed, and often touch less than lump, Light-headedness, the tired fear of body is cold, very then cardiopalmus, breathe hard, pale tongue, deficient and thready pulse or string Grating; As held blood stasis under the arm, then hardness in the lower abdomen pain, the many purples of body of the tongue are dim; The disease such as then have abdominal distention uncomfortable in chest, large loose stool thin of the stagnation of QI of holding concurrently.Puerperal, lower abdomen pain was main person, claimed puerperal abdonimal pain.Common with new puerpera, the contraction pain caused when referring to uterine contraction in puerperal, also known as " puerperal pain ", " uterine contraction pain ".
Puerperal abdonimal pain is included into by the traditional Chinese medical science " puerperal treats pain in abdomen ", " after-pains " category.The cause of disease be puerperal QI-blood circulation smooth, the stagnant stagnation of QI and blood may bring about pain of the stasis of blood, can due to blood trouble in puerperal, vessels of the whole body being deficient, and blood-deficiency and QI-insufficiency, carries out unable, so that thrombosis and the stasis of blood is stagnant; Also can due to puerperal asthenia, cold-evil takes advantage of a weak point, and blood is cold coagulation, stops in blood stasis, stagnation of QI and blood may bring about pain and causing.Western medicine claims " uterine contraction pain ", " puerperal pain ", belong to physiological phenomenon, generally do not need treatment.The a burst of aggravation if suffer from abdominal pain, is difficult to stand, or continuous and dull pain in the abdomen, and pain endlessly, affects perinatal health, be then morbid state, should treat.
Domestic and international to the puerperal abdonimal pain treatment Therapeutic Method adopting doctor trained in Western medicine at present more, desirable specific medicament is not still had for treatment puerperal abdonimal pain, although some medicine has certain effect to gynaecopathias such as puerperal abdonimal pains, but its therapeutic effect is unsatisfactory, and at the bottom of security performance, side effect is large, is not easy to clinical wide popularization and application.
Summary of the invention
The invention provides a kind of medicine and the preparation method that are used for the treatment of puerperal abdonimal pain; Medicine of the present invention have enrich blood invigorate blood circulation, effect of antalgic, circulation of qi promoting dissipating blood stasis, expelling wind and removing dampness, to the abdominal pain symptom caused puerperal, there is significant curative effect, safe and reliable, without any side effects, can suppress puerperal abdonimal pain, promote WomanHealth and have positive effect, clinical trial shows, to the total effective rate of puerperal abdonimal pain patient treatment up to 96.9%, clinic wide popularization and application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for puerperal abdonimal pain, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine of puerperal abdonimal pain, comprise following processing step:
(1) Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), gristle wind, Fructus Crataegi, Pollen Typhae, Radix Ribis davidii and Radix Lagerstroemia indica L. are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) Rhizoma Lycopi Lucidi, Celastrus gemmatus Loes., Herba Rubi parvifolii and Cortex Euonymi phellomanis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 80% of 6 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(3) Olibanum is cleaned, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, cross 180 order fine powders;
(4) Radix seu Caulis Kadsurae Heteroclitae, Herba Lycopi and Herba leonuri pseudoma cranthi are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(5) Herba artemisiae lactiflorae and Rhizoma Dioscoreae Cirrhosae are cleaned, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make pill, obtain the medicine being used for the treatment of puerperal abdonimal pain of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): mildly bitter flavor, warm in nature.Expelling wind and removing dampness, promoting blood circulation and stopping pain.Dispelling the wind and dampness pathogens arthralgia pain, stomachache, injury and bone fracture, traumatic hemorrhage." the practical Chinese herbal medicine in Guangxi newly selects ": " promoting the circulation of QI to relieve pain, promoting blood circulation and detumescence, strengthening bone and muscle.Control acute rheumatic arthritis, stomachache, fracture, bruise, lumbago and skelalgia, paralysis."
Rhizoma Lycopi Lucidi: sweet in the mouth, pungent, property is put down.Invigorate blood circulation, QI invigorating, disappear water.Cure mainly haematemesis, epistaxis, puerperal abdonimal pain, leukorrhagia." Japan hanako materia medica " carries: " only serious epistaxis, spits blood, puerperal cardiac and abdominal pain.”
Gristle wind: sweet in the mouth, micro-puckery, property is put down; Return liver, kidney channel.Expelling wind and removing dampness, eliminating stasis to stop pain.Cure mainly pain of dampness syndrome, lumbago, puerperal abdonimal pain, traumatic injury.
Olibanum: bitter in the mouth, property is pungent, warm; Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.Cure mainly the epigastric pain of the stasis blocking stagnation of QI, rheumatic arthralgia, traumatic injury, dysmenorrhea, puerperal abdonimal pain." detailed outline " carries: " all poison of eliminating carbuncle cellulitis, the heart is protected in Tuoli, and analgesic therapy of invigorating blood circulation, stretches muscle, controls married woman's difficult labour, injured." modern medicine study confirmation, Olibanum has analgesia bacteriostasis.
Celastrus gemmatus Loes.: bitter in the mouth, pungent, property is put down; Return liver, stomach warp.Expelling wind and removing dampness, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Cure mainly rheumatic arthralgia, traumatic injury, menoxenia, amenorrhea, puerperal abdonimal pain, stomachache, colic, sore, carbuncle and painful swelling, fracture, rubella, eczema, herpes zoster, venom.
Radix seu Caulis Kadsurae Heteroclitae: acrid in the mouth, hardship, warm in nature; Return spleen, stomach, Liver Channel.Expelling wind and removing dampness, promoting the circulation of QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic arthralgia, stomachache, stomachache, dysmenorrhea, puerperal abdonimal pain, traumatic injury, chronic lambago and skelalgia." Guangxi Chinese herbal medicine " carries: " promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, wind-damp dispelling.Control traumatic injury, rheumatic ostalgia, dysmenorrhea, puerperal abdonimal pain, acute/chronic gastroenteritis.”
Herba Lycopi: bitter in the mouth, pungent, slightly warm in nature; Return liver, spleen channel.Blood circulation promoting and blood stasis dispelling, line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, edema." property of medicine opinion " carries: " main puerperal abdonimal pain, frequently produce vim and vigour and to decline cold one-tenth labor, thin win, controls again the whole body appearance swollen greatly, housewife's human blood drop lumbago.”
Fructus Crataegi: sour in the mouth, sweet, slightly warm in nature; Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well." detailed outline " carries: " dissipating fluid-retention is eaten, and disappear meat Ji ， mass in the abdomen, phlegm retention feeling of fullness acid regurgitation, stagnant blood pain with distension.”
Pollen Typhae: sweet in the mouth, property is put down; Return liver, pericardium channel.Hemostasis, blood stasis dispelling, treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain." Japan hanako materia medica " carries: " controlling (top), to flutter blood vexed, evacuation of pus, furuncle, married woman's leukorrhagia, and the moon waits irregular, vim and vigour cardiac and abdominal pain; pregnant pregnant people's hematochezia fetal abortion, blood Yun mass resulting from the blood stasis, youngster rests the head on shoot, urinary obstruction, and hemorrhoidal hamorrhage rushes down blood; urticaria toxic swelling, and serious epistaxis is spitted blood, stimulating milk secretion, and stopping leak is smart, dysentery.Removing blood stasis detumescence is raw to be made, and tonifying blood and arresting bleeding is fried and used.”
Radix Ribis davidii: puckery, hardship, slightly warm in nature; Return liver,spleen,kidney warp.Blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons is regulated the flow of vital energy.Cure mainly rheumatic arthritis, menoxenia, amenorrhea lumbago, puerperal abdonimal pain, dysentery." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of relaxing muscles and tendons to promote blood circulation, stasis-dispelling and pain-killing, bone and muscle strengthening.For rheumatic arthritis, menoxenia, lumbago.”
Herba Rubi parvifolii: bitter in the mouth, puckery, cool in nature, nontoxic; Return liver, lung, kidney channel.Heat-clearing and toxic substances removing, dissipating blood stasis stops blooding, and parasite killing treats skin ulcer.Cure mainly cold, fever, cough expectorant blood, dysentery, traumatic injury, puerperal abdonimal pain, scabies, furuncle and phyma, traumatic hemorrhage." Nanning City's medicine will " carries: " dissipating blood stasis, pain relieving are reduced phlegm.Control traumatic injury, cough, puerperal the stasis of blood pain, bloody dysentery, hot eye.”
Herba leonuri pseudoma cranthi: acrid in the mouth, micro-hardship, cold nature.Promoting blood flow to regulate menstruation, removing toxic substances and promoting subsidence of swelling.Cure mainly menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, metrorrhagia, traumatic pain, carbuncle sore.Supplement to the Herbal carries: " main removing blood stasis.Puerperal abdonimal pain, liquor takes it; Also deposited furuncle is smashed to pieces.”
Herba artemisiae lactiflorae: sweet in the mouth, micro-hardship, property is put down.Vital energy regualting and blood circulation-promoting, regulating menstruation dampness removing, removing toxic substances and promoting subsidence of swelling.For menoxenia, amenorrhea, chronic hepatitis, liver cirrhosis, oedema due to nephritis, leucorrhea, urticaria, abdominal distention, hernia; Traumatic injury is controlled in external, traumatic hemorrhage, burn and scald, skin infection, eczema." south of the Five Ridges gather medicinal herbs record " carries: " promoting blood circulation to restore menstrual flow, treats cholera watery diarrhea, and only incised wound is hemorrhage.Control burn, heart pain, watery distension, size is had blood in stool.”
Radix Lagerstroemia indica L.: mildly bitter flavor, cold nature.Clearing away heat-damp and promoting diuresis, promoting blood circulation and hemostasis, pain relieving.Cure mainly dysentery, edema, burn and scald, eczema, eczema, carbuncle sore tumefacting virus, traumatic injury, metrorrhagia, migraine, toothache, dysmenorrhea, puerperal abdonimal pain.
Rhizoma Dioscoreae Cirrhosae: bitter in the mouth, cool in nature, mild toxicity.Promoting blood circulation and hemostasis, regulating QI to relieve pain, heat-clearing and toxic substances removing.Cure mainly hemoptysis, spitting of blood, hematemesis, epistaxis, hematuria, has blood in stool, metrorrhagia, menoxenia, dysmenorrhea, amenorrhea, puerperal abdonimal pain, abdominal distention, erputive abdominal disease, toxic-heat and blood stasis, watery diarrhea, arthralgia, treating swelling and pain by traumatic injury, furuncle, herpes zoster, traumatic hemorrhage." Guizhou side's medicine among the people collection " carries: " dysentery relieving disease.Control puerperal abdonimal pain, tympanites; Control asthma again.”
Cortex Euonymi phellomanis: cold in nature, bitter in the mouth; Enter liver, lung two warp.Removing blood stasis falls tire, regulating menstruation Radix Dipsaci.Control puerperal abdonimal pain, metrorrhagia hematochezia, rheumatalgia.
The present invention compared with prior art, has following beneficial effect:
Medicine of the present invention have enrich blood invigorate blood circulation, effect of antalgic, circulation of qi promoting dissipating blood stasis, expelling wind and removing dampness, to the abdominal pain symptom caused puerperal, there is significant curative effect, safe and reliable, without any side effects, can suppress puerperal abdonimal pain, promote WomanHealth and have positive effect, clinical trial shows, to the total effective rate of puerperal abdonimal pain patient treatment up to 96.9%, clinic wide popularization and application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Be used for the treatment of a preparation method for the medicine of puerperal abdonimal pain, comprise following processing step:
(1) Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), gristle wind, Fructus Crataegi, Pollen Typhae, Radix Ribis davidii and Radix Lagerstroemia indica L. are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) Rhizoma Lycopi Lucidi, Celastrus gemmatus Loes., Herba Rubi parvifolii and Cortex Euonymi phellomanis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 80% of 6 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(3) Olibanum is cleaned, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, cross 180 order fine powders;
(4) Radix seu Caulis Kadsurae Heteroclitae, Herba Lycopi and Herba leonuri pseudoma cranthi are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(5) Herba artemisiae lactiflorae and Rhizoma Dioscoreae Cirrhosae are cleaned, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make pill, obtain the medicine being used for the treatment of puerperal abdonimal pain of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1 (every 0.8g); Within 5 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine being used for the treatment of puerperal abdonimal pain, select the routine clinical observation of puerperal abdonimal pain patient 130, patient is divided into treatment group and matched group two groups at random, treatment group women 65 example, 18 ~ 43 years old age, 30.5 years old mean age, the course of disease 1 ~ 2 year; Matched group women 65 example, 19 ~ 42 years old age, 29.7 years old mean age, the course of disease 1 ~ 2 year; The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 1 (every 0.8g); Within 5 days, be 1 course for the treatment of, take 2 ~ 4 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding; Matched group takes Nuo Fosha star capsule, oral, a 400mg, 2 times on the one.
3, efficacy determination:
(1) cure: pain symptom disappears, and physical recovery is normal.
(2) effective: pain symptom obviously alleviates, health recovers normal substantially.
(3) effective: pain symptom is link to some extent, and health obviously recovers normal.
(4) invalid: by treating rear pain symptom without alleviating or increasing the weight of.
4, result:
| Number of cases | Cure | Effective | Effectively | Invalid | Cure rate | Total effective rate | |
| Treatment group | 65 | 35 | 16 | 12 | 2 | 53.8% | 96.9% |
| Matched group | 65 | 11 | 15 | 16 | 23 | 16.9% | 64.6% |
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Shen, female, 20 years old, people from Shijiazhuang, Hebei.Patient's lower abdomen pain in 5 days puerperal, tenderness, obtain burning pain and delay, lochia amount is few, and not smooth not smooth color purple secretly has block, alleviation of pain under block, companion's distending pain in the chest and hypochondrium.After being in hospital, oral Drug therapy of the present invention, every day 2 times, each 1 time sooner or later, each 1 (every 0.8g); After taking 1 course for the treatment of, colic symptoms is clearly better, and after continuing to take 1 course for the treatment of, colic symptoms disappears, and disease is fully recovered, and has no recurrence.
2, health, female, 25 years old, people from Jinzhou, Liaoning.During 6 days puerperal of patient, hot summer days covet cool, and night does not build abdominal part, so that are affected by the cold, next morning lower abdomen pain, pain gesture is violent, and lochia is only poly-, soreness of the loins and weakness of the limbs, dizziness order flower.After being in hospital, give medicine of the present invention, after taking 1 course for the treatment of, conscious lower abdomen pain symptom obviously alleviates, and after taking 2 courses for the treatment of, all diseases disappear, and physical recovery is healthy.
3, certain is turned round and look at, female, 28 years old, people from Liaoyuan, Jilin.After patient's cesarean, pelvic adhesion occurs, suffer from abdominal pain 1 year, outer court HSG reminds on bilateral salpingo and lifts, pelvic adhesion, and B ultrasonic prompting uterus adnexa has no obvious exception.Preoperative planning routine blood test: leukocyte: 4.5 × 10 (9)/L, erythrocyte: 4.45 × 10 (12)/L, hemoglobin: 109g/L, platelet: 300 × 10 (9)/L, abo blood group: O type, RH (D) blood group: positive; Electrocardiogram, rabat, blood coagulation four, Liver and kidney merit are all without significantly peculiar; C-hepatitis antibody, syphilis antibody, aids antibody are feminine gender; Leucorrhea convention: clean degree III degree, without infusorian mycete.AD: chronic pelvic pain, pelvic adhesion, cesarean postoperate.Give medicine of the present invention, after taking 1 course for the treatment of, above-mentioned colic symptoms obviously alleviates, and after taking 3 courses for the treatment of, all diseases are eliminated, and follow up a case by regular visits to without recurrence after 1 year.
4, money, female, 32 years old, people from Mudanjiang, Heilungkiang.Patient's cesarean has lower abdomen indistinctly to do the situation of pain always after 3 months, increase the weight of when particularly exerting all one's strength large, and with symptoms such as leucorrhea jaundice.After diagnosis, start to take medicine of the present invention, check after taking 1 course for the treatment of of the present invention, puerperal abdonimal pain turns for the better by and large, and take again 1 course for the treatment of of medicine of the present invention, puerperal abdonimal pain disappears, and physical recovery is healthy, follows up a case by regular visits to and does not recur.
5, side certain, female, 27 years old, people from Changchun, Jilin.Patient produces two wheat harvesting periods, and side cutting knife mouth is itched a little, the dull pain that lower abdomen is always a little very slight, very uncomfortable sensation, and once in a while with very light very light pink colour mucus, after admission examination, have light inflammation, because being in age of sucking, doctor advised takes medicine of the present invention, checks after taking 3 courses for the treatment of of the present invention, and puerperal abdonimal pain disappears, physical recovery is healthy, follows up a case by regular visits to and does not recur.
6, season, female, 26 years old, people from Weihai in Shandong province.Patient does cesarean 1 year, and there are two not only hard but also enclosed mass of circle on wound both sides, before in the period pain severity along with through after just so not bitterly, go to a lot of hospital to seek medical advice and all can not check reason, catch cervical erosion now, after diagnosis, start to take medicine of the present invention, check after taking 1 course for the treatment of of the present invention, puerperal abdonimal pain turns for the better by and large, and takes again 2 courses for the treatment of of medicine of the present invention, and puerperal abdonimal pain disappears, physical recovery is healthy, follows up a case by regular visits to and does not recur.
Claims (5)
1. be used for the treatment of a medicine for puerperal abdonimal pain, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 48 ~ 74 parts of Rhizoma Lycopi Lucidi 45 ~ 71 parts of gristle wind 37 ~ 63 parts of Olibanums 32 ~ 59 parts
Celastrus gemmatus Loes. 32 ~ 58 parts of Radix seu Caulis Kadsurae Heteroclitae 30 ~ 57 parts of Herba Lycopi 28 ~ 57 portions of Fructus Crataegis 24 ~ 51 parts
Pollen Typhae 22 ~ 50 parts of Radix Ribis davidiis 18 ~ 47 parts of Herba Rubi parvifolii 16 ~ 46 parts of Herba leonuri pseudoma cranthi 12 ~ 40 parts
Herba artemisiae lactiflorae 11 ~ 37 parts of Radix Lagerstroemia indica L.s 8 ~ 34 portions of Rhizoma Dioscoreae Cirrhosaes 5 ~ 26 parts of Cortex Euonymi phellomaniss 3 ~ 22 parts.
2. a kind of medicine being used for the treatment of puerperal abdonimal pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 52 ~ 70 parts of Rhizoma Lycopi Lucidi 49 ~ 67 parts of gristle wind 41 ~ 59 parts of Olibanums 37 ~ 55 parts
Celastrus gemmatus Loes. 36 ~ 54 parts of Radix seu Caulis Kadsurae Heteroclitae 34 ~ 52 parts of Herba Lycopi 32 ~ 52 portions of Fructus Crataegis 28 ~ 46 parts
Pollen Typhae 27 ~ 46 parts of Radix Ribis davidiis 22 ~ 42 parts of Herba Rubi parvifolii 21 ~ 41 parts of Herba leonuri pseudoma cranthi 17 ~ 35 parts
Herba artemisiae lactiflorae 15 ~ 33 parts of Radix Lagerstroemia indica L.s 12 ~ 30 portions of Rhizoma Dioscoreae Cirrhosaes 9 ~ 22 parts of Cortex Euonymi phellomaniss 7 ~ 19 parts.
3. a kind of medicine being used for the treatment of puerperal abdonimal pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 57 ~ 65 parts of Rhizoma Lycopi Lucidi 54 ~ 62 parts of gristle wind 46 ~ 54 parts of Olibanums 42 ~ 50 parts
Celastrus gemmatus Loes. 41 ~ 49 parts of Radix seu Caulis Kadsurae Heteroclitae 39 ~ 47 parts of Herba Lycopi 37 ~ 45 portions of Fructus Crataegis 33 ~ 41 parts
Pollen Typhae 32 ~ 40 parts of Radix Ribis davidiis 27 ~ 37 parts of Herba Rubi parvifolii 26 ~ 36 parts of Herba leonuri pseudoma cranthi 22 ~ 30 parts
Herba artemisiae lactiflorae 20 ~ 28 parts of Radix Lagerstroemia indica L.s 17 ~ 25 portions of Rhizoma Dioscoreae Cirrhosaes 13 ~ 17 parts of Cortex Euonymi phellomaniss 11 ~ 15 parts.
4. a kind of medicine being used for the treatment of puerperal abdonimal pain according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 61 parts of Rhizoma Lycopi Lucidi 58 parts of gristle wind 50 parts of Olibanums 46 parts
Celastrus gemmatus Loes. 45 parts of Radix seu Caulis Kadsurae Heteroclitae 43 parts of Herba Lycopi 41 portions of Fructus Crataegis 37 parts
Pollen Typhae 36 parts of Radix Ribis davidiis 32 parts of Herba Rubi parvifolii 31 parts of Herba leonuri pseudoma cranthi 26 parts
Herba artemisiae lactiflorae 24 parts of Radix Lagerstroemia indica L.s 21 portions of Rhizoma Dioscoreae Cirrhosaes 15 parts of Cortex Euonymi phellomaniss 13 parts.
5. as described in any one of Claims 1 to 4, be used for the treatment of a preparation method for the medicine of puerperal abdonimal pain, it is characterized in that: comprise following processing step:
(1) Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), gristle wind, Fructus Crataegi, Pollen Typhae, Radix Ribis davidii and Radix Lagerstroemia indica L. are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(2) Rhizoma Lycopi Lucidi, Celastrus gemmatus Loes., Herba Rubi parvifolii and Cortex Euonymi phellomanis are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 80% of 6 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.20 ~ 1.25 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(3) Olibanum is cleaned, put in pot to fry with slow fire and slightly see melting point to surface, slightly in yellow, take out after cooling, grind into powder, 180 object fine powders must be;
(4) Radix seu Caulis Kadsurae Heteroclitae, Herba Lycopi and Herba leonuri pseudoma cranthi are mixed, carry out pulverization process after mix homogeneously, grind into powder, 160 object fine powders must be, for subsequent use;
(5) Herba artemisiae lactiflorae and Rhizoma Dioscoreae Cirrhosae are cleaned, shady and cool place dries, and chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make pill, obtain the described medicine being used for the treatment of puerperal abdonimal pain.
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| CN105012868A (en) * | 2015-07-09 | 2015-11-04 | 杜仁波 | Traditional Chinese medicine composition for treating postpartum abdominal pain |
| CN105169144A (en) * | 2015-09-11 | 2015-12-23 | 韩淑臻 | Traditional Chinese medicine preparation used for treating postpartum abdominal pain and preparation method |
| CN105106771A (en) * | 2015-09-18 | 2015-12-02 | 韩淑臻 | Medicine for recovery of puerperae subjected to caesarean birth operations and preparation method of medicine |
| CN105250486A (en) * | 2015-10-10 | 2016-01-20 | 汕头大学医学院第一附属医院 | Traditional Chinese medicine for treating postpartum abdominal pain due to blood stasis and metrorrhagia complicaitons |
| CN107050258A (en) * | 2016-11-10 | 2017-08-18 | 刁媛媛 | A kind of pharmaceutical composition for treating postpartum abdominal pain |
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| CN101112519A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating postpartum tormina |
| CN101112596A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine composition for treating postpartum tormina |
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| CN101112596A (en) * | 2007-08-29 | 2008-01-30 | 北京艺信堂医药研究所 | Chinese traditional medicine composition for treating postpartum tormina |
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