CN102895400B - Traditional Chinese medicine decoction for treatment of diabetic constipation of elderly - Google Patents

Abstract

The invention relates to the field of pharmaceutical formulations, in particular to a traditional Chinese medicine decoction for treating senile diabetic constipation. ～17 parts, 5～9 parts of raw astragalus, 2～4 parts of fairy spleen, 4～8 parts of cistanche, 12～16 parts of citrus aurantium, 5～10 parts of rhubarb, 14～20 parts of Bupleurum, 4～8 parts of hawthorn , 3-6 parts of forsythia, 8-18 parts of fat sea, 8-18 parts of mulberry, 6-16 parts of cassia seed, 5-20 parts of walnut kernel, 5-20 parts of fig, 15-20 parts of falling sunflower, raw Polygonum multiflorum 4 to 8 parts, 2 to 4 parts of Cynomorium, 9 to 15 parts of Radix Paeoniae Alba, and 5 to 16 parts of Dilong, mix the above 21 kinds of raw materials, soak in water, decoct and remove the residue to obtain the filtrate. The invention is used for treating senile diabetic constipation, has a high cure rate, is not easy to relapse, has no toxic and side effects, and has low cost.

Description

Traditional Chinese Medicine Decoction for Treating Senile Diabetic Constipation

technical field

The invention relates to a Chinese patent medicine preparation, in particular to a Chinese medicine decoction for treating senile diabetic constipation.

Background technique

As we all know, elderly diabetic patients are prone to constipation due to old age, weak spleen and stomach, insufficient yang energy, or sedentary inactivity. Those with cerebral, renal and macrovascular complications can also aggravate their complications. Therefore, it is very necessary to solve diabetic constipation. But doctor trained in Western medicine still does not have specific medicine to this disease, mostly adopts laxative, gastric function medicine etc., for severe constipation patient regular enema or rectal myotomy, the effect is not ideal enough. And the method and the medicament of existing traditional Chinese medicine treatment senile diabetic constipation, generally exist the shortcomings such as poor therapeutic effect, easy recurrence, side effect.

Contents of the invention

The purpose of the present invention is to overcome the above-mentioned existing technical deficiencies, and to provide a traditional Chinese medicine decoction for treating senile diabetic constipation, which has good therapeutic effect, is not easy to relapse, has no side effects and is low in cost.

The technical solution adopted by the present invention to solve the above-mentioned technical problems is: a traditional Chinese medicine decoction for treating senile diabetic constipation, characterized in that the weight parts of raw materials are: 6-14 parts of angelica, 4-6 parts of rehmannia, 8-6 parts of fenugreek 17 parts, 5-9 parts of raw astragalus, 2-4 parts of fairy spleen, 4-8 parts of cistanche, 12-16 parts of citrus aurantium, 5-10 parts of rhubarb, 14-20 parts of Bupleurum, 4-8 parts of hawthorn, 3-6 parts of forsythia, 8-18 parts of fat sea, 8-18 parts of mulberry, 6-16 parts of cassia seed, 5-20 parts of walnut kernel, 5-20 parts of fig, 15-20 parts of falling sunflower, 4 raw Polygonum multiflorum ~ 8 parts, Cynomorium 2 ~ 4 parts, Radix Paeoniae Alba 9 ~ 15 parts, Dilong 5 ~ 16 parts, the above 21 kinds of raw materials are mixed, soaked in water, and the slag is removed after decoction to obtain the filtrate.

The preferred range of parts by weight of raw materials of the present invention is: Angelica 8, Rehmannia 5, Fragrant rafter 15, Raw Astragalus 7, Lingpi 3, Cistanche 6, Citrus aurantium 14, Rhubarb 8, Bupleurum 16, Hawthorn 6, Forsythia 5, Plump sea 15, mulberry 15, cassia 12, walnut kernel 16, fig 15, Luokui 17, raw Polygonum multiflorum 6, Cynomorium 3, Radix Paeoniae Alba 13, Dilong 10.

The invention is used for treating senile diabetic constipation, has a high cure rate, is not easy to relapse, has no toxic and side effects, and has low cost.

Detailed ways

Below in conjunction with embodiment the present invention will be further described:

Example 1:

The present embodiment uses the raw material medicine of the following proportioning by weight as a medicine: Angelica 8, Shengdi 5, Fragrant rafter 15, Raw Astragalus 7, Xianlingpi 3, Cistanche 6, Citrus aurantium 14, Rhubarb 8, Bupleurum 16, Hawthorn 6. Forsythia 5, fat sea 15, mulberry 15, cassia 12, walnut kernel 16, fig 15, Luokui 17, raw Polygonum multiflorum 6, Cynomorium 3, white peony 13, earthworm 10. Take the above-mentioned 21 raw materials with a total weight of 204 grams, add water to 21 Chinese herbal medicines at room temperature to 1000-1200ml, soak for 4-6 hours, boil with strong fire, simmer for 60-80 minutes, remove residue to obtain about 300ml of filtrate, Add 300-400ml of water to the dregs of the medicine, decoct for 30-40 minutes, remove the dregs to obtain 100ml of filtrate, and obtain a total of about 400ml of decoction, which is a traditional Chinese medicine decoction for treating senile diabetic constipation. Put it into a graduated sterile glass bottle and seal the bottle cap for later use. Take it orally on an empty stomach every day, twice in the morning and evening, about 200ml each time, 7 days as a course of treatment, and enter the next course of treatment with an interval of 1 day. Take it until the clinical symptoms and signs disappear or alleviate. Generally, 5 courses of treatment are required.

The present invention selects angelica, raw land, fragrant rafters, raw astragalus, fairy spleen, cistanche, citrus aurantium, rhubarb, Bupleurum, hawthorn, forsythia, fat sea, mulberry, cassia, walnut kernel, fig, falling sunflower, raw Polygonum multiflorum , Cynomorium, Radix Paeoniae Alba, and Earthworm are combined, and after the combination, the efficacy of each drug produces a synergistic effect, thereby effectively treating senile diabetic constipation. Among them, angelica nourishes blood and activates blood, regulates menstruation and relieves pain, moistens intestines and relieves constipation. It is used for blood deficiency and chlorosis, dizziness and palpitations, irregular menstruation, amenorrhea dysmenorrhea, abdominal pain due to deficiency and cold, constipation due to dryness of the intestine, arthralgia due to rheumatism, injury from falls, ulcers and sores. Rehmannia root has the effect of nourishing yin and promoting body fluid. It is used for thirsty wounds, internal heat and quenching thirst, treating febrile diseases that hurt yin, intestinal dryness and constipation. Fragrant rafters have the effects of regulating qi and resolving phlegm, relieving pain and reducing inflammation. Raw Radix Astragali nourishes qi and strengthens the exterior, diuretic toxin, expels pus, suppresses sores and promotes granulation, used for qi deficiency and fatigue, lack of appetite, loose stools, depression of central qi, chronic diarrhea and prolapse of the anus, bloody stool and metrorrhagia, spontaneous sweating due to exterior deficiency, edema due to qi deficiency and astragalus round Tablets, carbuncle and gangrene are difficult to ulcerate, chronic ulceration does not restrain, blood deficiency, flaccidity and jaundice, internal heat and thirst; chronic nephritis, proteinuria, diabetes. Xianling Spleen Dampness Kidney Strengthening Yang, Expelling Wind and Dampness, Indications: Impotence, nocturnal emission, enuresis, cold pain in the waist and knees, limp limbs and cold-damp arthralgia caused by kidney yang deficiency, spleen and kidney yang deficiency, cold pain in the abdomen, Eat less and have diarrhea. Herba Cistanche invigorates kidney yang, nourishes essence and blood, moisturizes the intestines and relieves constipation. It is used for impotence, infertility, soreness of the waist and knees, weakness of muscles and bones, dryness of the intestine and constipation. Citrus aurantium is a commonly used traditional Chinese medicine in clinical practice. It can dispel qi, dissipate swelling, relieve phlegm, and eliminate stagnation. It is often used clinically to treat chest and abdomen fullness, chest obstruction, pain, phlegm addiction, edema, food accumulation, constipation, gastroptosis, uterine prolapse, and anal prolapse. etc. Rhubarb has the effects of purging and attacking stagnation, clearing heat and cooling blood, purging fire and detoxifying, promoting blood circulation and removing blood stasis. Bupleurum bupleurum is bitter in taste and slightly cold in nature, returns to the liver and gallbladder meridians, has the functions of dispersing and reducing fever, soothing the liver, and raising yang. , prolapse of the anus embolism. Hawthorn has important medicinal value. Since ancient times, it has become a good medicine for invigorating the spleen and appetizing, eliminating stagnation, promoting blood circulation and reducing phlegm. Forsythia clears heat and detoxifies, dissipates stagnation and reduces swelling, relieves diarrhea. Indications: traditional Chinese medicine treats the initial onset of fever, wind-heat cold, fever, upset, sore throat, macule, erysipelas, scrofula, carbuncle sores, acute nephritis, Hot stranguria, Mongolian medicine for jaundice, intestinal tingling, "Xie Ri" disease, intestinal heat. Panda Dahai clears heat and nourishes the lungs, sore throat and detoxification, moistens the intestines and laxes the bowels. It is used for hoarseness due to lung heat, dry cough without phlegm, dry and sore throat, constipation due to heat accumulation, headache and red eyes. Traditional Chinese medicine believes that mulberries are sweet and sour, slightly cold in nature, and enter the heart, liver, and kidney meridians. They are nourishing and strong, nourishing the heart and improving intelligence. Dizziness, tinnitus, palpitation, irritability and insomnia, soreness of waist and knees, premature graying of beard and hair, thirst and dry mouth, dry stool and other symptoms. Semen Cassiae has the effects of lowering blood pressure, lowering blood lipids, and antibacterial effects, and has certain curative effects in the treatment of hyperlipidemia. Walnut kernel nourishes the kidney and solidifies the essence; warms the lung and calms asthma; moistens the intestines and relieves constipation, treats low back pain and weak feet; frequent urination; enuresis; impotence; spermatorrhea; chronic cough and shortness of breath; intestinal dryness and constipation. Fig nature and flavor: sweet; cool in nature, meridian distribution: lung; stomach; large intestine meridian, functions and indications: clearing away heat and promoting body fluid; invigorating the spleen and appetizing; detoxifying and reducing swelling, controlling sore throat; hoarseness due to dry cough; scarce milk; intestinal heat and constipation; Loss of appetite; indigestion. Luo Kui is also known as rouge, fungus, rattan, and tofu. It belongs to the family of La Kui. It is sweet, light, cool, and non-toxic. Polygonum multiflorum is used raw and has a strong laxative effect, and its active ingredient chrysophanol can promote intestinal movement in animals. Cynomorium Indications: impotence and premature ejaculation, yin failure and blood exhaustion; Qi deficiency and yin deficiency, dry stool, frequent urination, hematuria, dripping endlessly; soreness of the waist and knees, fatigue and weakness; aversion to cold and pain in the limbs. Radix Paeoniae Alba nourishes blood and softens the liver, relieves pain in the middle, restrains yin and absorbs sweat, controls pain in the chest and abdomen, hypochondriac, abdominal pain, spontaneous sweating, night sweats, and fever due to yin deficiency. Earthworm is cold in nature and salty in taste. Functions: clearing away heat, calming liver, relieving asthma, dredging collaterals. Return liver, stomach, lung, urinary bladder channel. Function: clearing away heat and calming liver, quenching wind and relieving convulsions, relieving asthma, promoting diuresis, dredging collaterals and removing numbness, mainly treating high fever and irritability, convulsions, wheezing and coughing due to lung heat, heat stagnation and anuria, numbness and numbness in limbs.

Each crude drug of the present invention can also be realized by the embodiment that the weight ratio listed in the following table is mixed. Its processing technology is identical with embodiment 1. (Unit: parts by weight)

Clinical observation of drug treatment of the present invention for senile diabetic constipation

1. Diagnostic criteria: ① Meet the diagnostic criteria for type 2 diabetes in "Practical Internal Medicine" [1]; ② Prolonged defecation time, the interval between two adjacent defecations is > 72 hours, or the stool is dry and hard, or even like sheep feces or Agglomerates, strenuous defecation, or difficult stools that are not dry and hard [2]; ③ Colonoscopy or barium meal contrast to exclude organic lesions of the colon and rectum.

2. Clinical data: 64 patients were randomly selected in clinical practice, and all patients were diagnosed with senile diabetic constipation.

3, treatment method: medicine of the present invention takes once a day, respectively clothes 200ml sooner or later, 7 days are 1 course for the treatment of, enter next course for the treatment of at interval 1 day, use 5 courses for the treatment of continuously.

4. Efficacy criteria: cured: normal stool, all symptoms disappear; markedly effective: constipation is significantly improved, the interval time and stool quality are close to normal, or the stool is slightly dry and the interval between defecation is within 72 hours; effective: the interval between defecation is shortened by 1 day or more Improve stool dryness; Invalid: Constipation does not relieve.

5. Therapeutic effect: 64 cases were treated with the present invention, 51 cases were cured as a result, 6 cases were markedly effective, 3 cases were effective, and 4 cases were ineffective, the total effective rate was 93.7%.

Claims (2)

1. a Chinese medicine decoction for the treatment of senile diabetic constipation, characterized in that the weight parts of the crude drug are: 6 to 14 parts of Angelica, 4 to 6 parts of Radix Rehmannia, 8 to 17 parts of Citron, 5 to 9 parts of Radix Astragali, 2-4 parts of Epimedium, 4-8 parts of Cistanche, 12-16 parts of Citrus aurantii, 5-10 parts of Rhubarb, 14-20 parts of Bupleurum, 4-8 parts of Hawthorn, 3-6 parts of Forsythia, 8 ～18 parts, 8～18 parts of mulberry, 6～16 parts of cassia seed, 5～20 parts of walnut kernel, 5～20 parts of fig, 15～20 parts of falling sunflower, 4～8 parts of raw Polygonum multiflorum, 2～4 parts of Cynomorium , Radix Paeoniae Alba 9～15 parts, earthworm 5～16 parts, after mixing above-mentioned 21 kinds of crude drugs, soak in water, remove the slag after decocting and obtain filtrate. 2. a kind of Chinese medicine decoction for the treatment of senile diabetic constipation according to claim 1 is characterized in that the parts by weight of said crude drug are Angelica 8, Rehmannia 5, Citron 15, Radix Astragali 7, Epimedium 3. Cistanche 6, Citrus aurantium 14, Rhubarb 8, Bupleurum 16, Hawthorn 6, Forsythia 5, Panda Dahai 15, Mulberry 15, Cassia 12, Walnut 16, Fig 15, Luokui 17, Polygonum multiflorum 6, lock Yang 3, Paeoniae Alba 13, Earth Dragon 10.