CN109620899A

CN109620899A - A kind of Chinese medicine composition and preparation method thereof prevented or treatment is caught a cold

Info

Publication number: CN109620899A
Application number: CN201910127329.7A
Authority: CN
Inventors: 高庆禄
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-02-20
Filing date: 2019-02-20
Publication date: 2019-04-16

Abstract

The embodiment of the invention discloses a kind of prevention or the Chinese medicine compositions and preparation method thereof for the treatment of flu, belong to technical field of traditional Chinese medicines, the Chinese medicine composition that the prevention or treatment are caught a cold is made of each component of following parts by weight: 3-8 parts of perilla leaf, 2-6 parts of radix saposhnikoviae, 2-5 parts of schizonepeta, 1-5 parts of Rhizoma Et Radix Notopterygii, 1-5 parts of Chinese ephedra, 2-5 parts of the root bark of tree peony, 1-5 parts of radix scrophulariae, 1-5 parts of Radix Glycyrrhizae, 2-5 parts of the root of Dahurain angelica, 1-4 parts of Exocarpium Citri Rubrum, 1-5 parts of gypsum, 2-5 parts of Radix Angelicae Sinensis, 1-5 parts of pueraria lobata, 1-5 parts of white ginseng, 3-5 parts of the tuber of pinellia, 1-5 parts of the root of purple-flowered peucedanum, 2-5 parts of the flower bud of lily magnolia, 2-5 parts of radix scutellariae.The embodiment of the present invention uses pure plant medicinal material, it is mixed through scientific compatibility, each raw material component has the effect of relieving exterior syndrome and dispelling cold, expelling wind and promoting the restoration of consciousness, heat-clearing and damp-drying drug, purging fire for removing toxin through dialectical compatibility, it is verified through clinical application for many years, suitable for preventing or treating common cold and influenza, there is significant in efficacy, medicinal peace, it has no toxic side effect, safe and reliable advantage.

Description

A kind of Chinese medicine composition and preparation method thereof prevented or treatment is caught a cold

Technical field

The present embodiments relate to technical field of traditional Chinese medicines, and in particular to it is a kind of prevention or treatment flu Chinese medicine composition and Preparation method.

Background technique

Flu is a kind of multiple diseases of a kind of common infectious disease of respiratory system and the mankind.According to infection disease The difference of poison, flu can be divided into common cold and influenza.

Common cold is commonly called as catching cold, and is by rhinovirus, coronavirus, Respiratory Syncytial Virus(RSV), adenovirus, parainfluenza virus The nasal cavity of equal initiations and the infection of the upper respiratory tract of throat, symptom includes: dry throat, is itched or burning pain, there is sneezing, nasal obstruction, stream The symptoms such as clear nasal mucus, hoarseness, cough, dysacousis.With low fever, slight chilly and headache.Common cold usually has certainly Sex-limited, human body can voluntarily be fully recovered by the immunological regulation of itself, and natural history is 5-7 days.

Influenza abbreviation influenza is the Acute respiratory infectious disease as caused by influenza virus.Influenza virus belongs to just Myxovirus section has high-affinity to the mucoprotein of respiratory mucosa cell surface.Human influenza virus be divided into first (A), second (B), Third (C) three type, can cause respiratory tract acute infection, and clinical manifestation is that onset is anxious, and constitutional symptom is heavier, high fever, headache, it is out of strength, Muscular stiffness symptom is obvious, and body temperature can reach 39-40 DEG C.Influenza has popularity, in outburst state, group's morbidity, recovery from illness needs 7-10d is longer.

Cold drug refers to the various medicines for treating flu, including Chinese patent drug, decoction, Western medicine, electuary etc., at present market On the cold drug pathological that spreads it is single, for example including analgesic-antipyretic, schneiderian membrance vasoconstrictor, histamine antagonist, in Pivot stimulant, antiviral agent etc., so that the indication of cold drug is narrow.Due to being lacked in flu early period to flu and cold drug cognition Weary, patient is easy to appear wrong medicine in medication, and less serious case aggravates the state of an illness, and severe one even causes death.

In view of this, the present invention is specifically proposed.

Summary of the invention

For this purpose, the embodiment of the present invention provides a kind of Chinese medicine composition and preparation method thereof prevented or treatment is caught a cold, with solution The narrow problem of certainly existing cold drug indication, Chinese medicine composition of the invention are verified through the clinical test of more than 50 years, have action fast Speed, wide adaptation range, the advantages of having no toxic side effect.

To achieve the goals above, the embodiment of the present invention provides the following technical solutions:

In the first aspect of embodiments of the present invention, a kind of Chinese medicine composition prevented or treatment is caught a cold is provided, Be made of each component of following parts by weight: 3-8 parts of perilla leaf, 2-6 parts of radix saposhnikoviae, 2-5 parts of schizonepeta, 1-5 parts of Rhizoma Et Radix Notopterygii, 1-5 parts of Chinese ephedra, 2-5 parts of the root bark of tree peony, 1-5 parts of radix scrophulariae, 1-5 parts of Radix Glycyrrhizae, 2-5 parts of the root of Dahurain angelica, 1-4 parts of Exocarpium Citri Rubrum, 1-5 parts of gypsum, 2-5 parts of Radix Angelicae Sinensis, pueraria lobata 1-5 Part, 1-5 parts of white ginseng, 3-5 parts of the tuber of pinellia, 1-5 parts of the root of purple-flowered peucedanum, 2-5 parts of the flower bud of lily magnolia, 2-5 parts of radix scutellariae.

Further, be made of each component of following parts by weight: 5 parts of perilla leaf, radix saposhnikoviae 4 parts, 3 parts of schizonepeta, 3 parts of Rhizoma Et Radix Notopterygii, 3 parts of Chinese ephedra, 4 parts of the root bark of tree peony, 2 parts of radix scrophulariae, 3 parts of Radix Glycyrrhizae, 3 parts of the root of Dahurain angelica, 2 parts of Exocarpium Citri Rubrum, 1 part of gypsum, 2.5 parts of Radix Angelicae Sinensis, 3.5 parts of pueraria lobata, 2 parts of white ginseng, 4 parts of the tuber of pinellia, 2.5 parts of the root of purple-flowered peucedanum, 3.5 parts of the flower bud of lily magnolia, 3 parts of radix scutellariae.

In the second aspect of embodiments of the present invention, the Chinese medicine group of the above-mentioned prevention of one kind or treatment flu is provided Close the preparation method of object, which comprises

Each raw material is put into pot, boiling is added to mention three times, the water that 8-10 times of raw material gross weight is measured is added for the first time and decocts 1.5-2 hours, the water that second of 5-8 times of raw material gross weight of addition is measured decocted 1-1.5 hours, and raw material gross weight 3- is added in third time 5 times of amount water decoct 0.5-1 hours, and decocting liquid merging three times staticly settles 18-36 hours, supernatant are taken, when being concentrated under reduced pressure into 80 DEG C Relative density is the clear cream of 1.1-1.2.

Further, which comprises

Each raw material is put into pot, boiling is added to mention three times, the water that 8 times of raw material gross weight amounts are added for the first time decocts 2 hours, The water of second of addition, 6 times of raw material gross weight amounts decocts 1 hour, and it is small that 4 times of amount water decoctions 0.5 of raw material gross weight are added in third time When, decocting liquid merging three times staticly settles 30 hours, takes supernatant, and relative density is the clear of 1.1-1.2 when being concentrated under reduced pressure into 80 DEG C Cream.

In the third aspect of embodiments of the present invention, a kind of Chinese materia medica preparation prevented or treatment is caught a cold, institute are provided State Chinese materia medica preparation Chinese medicine composition as made from above-mentioned Chinese medicine composition or above-mentioned method and pharmaceutically acceptable auxiliary material It is made.

Further, the preparation is any one of capsule, tablet, pill, granule.

In the fourth aspect of embodiments of the present invention, the above-mentioned Chinese medicine composition of one kind is provided in preparation for controlling Treat the application in the drug of flu.

Further, the flu includes influenza and common cold.

The action and efficacy of each raw material used in the present invention is described below:

Perilla leaf: for the dried leaf (or with spray) of Lamiaceae plant purple perilla Perilla frutescens (L.) Britt.Summer It is harvested when Ji Zhiye is luxuriant, removes impurity, dry.Nature and flavor are acrid in flavour and warm in nature.Channel tropism return lung, the spleen channel.Major function relieving exterior syndrome and dispelling cold, promoting the circulation of qi Stomach function regulating.For anemofrigid cold, evil of vomitting of coughing, the vomiting of pregnancy, fish and crab poisoning.

Radix saposhnikoviae: for the drying of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk. Root.The root of scape plant is not taken out in spring, the excavation of two season of autumn, removes fibrous root and silt, dries.Nature and flavor acrid, sweet, warm.Channel tropism return bladder, Liver, the spleen channel.Major function inducing diaphoresis to dispel wind wins wet, relieving convulsion.For cold headache, rheumatic arthralgia, rubella itch, tetanus.

Schizonepeta: for the dry aerial parts of Lamiaceae plant schizonepeta Schizonepeta tenuifolia Briq..Summer, Two season of autumn, the flowers are in blossom to top, fringe it is green when tap, remove impurity, dry.Nature and flavor are pungent, tepor.Channel tropism return lung, Liver Channel.Major function solution Table relieve heat, promoting eruption.For catching a cold, have a headache, morbilli, rubeola, sore from the beginning of.Fry charcoal treating hematochezia, metrorrhagia and metrostaxis, postpartum anemic fainting.

Rhizoma Et Radix Notopterygii: for umbelliferae Rhizoma Et Radix Notopterygii (back wing celery) Notopterygium incisum Ting ex H.T.Chang Or the dry rhizome and root of notopterygium forbesii Notopterygium forbesii Boiss..Spring, the excavation of two season of autumn, remove fibrous root And silt, it dries.Nature and flavor are pungent, bitter, temperature.Channel tropism returns bladder, kidney channel.Major function cold dispelling, wind-dispelling dehumidify, analgesic.For chill Cold headache, rheumatic arthralgia, aching pain in shoulder and back.

Chinese ephedra: for Ephedraceae plant ephedra sinica Ephedra sinica Stapf, epheday intermedia Ephedra intermedia The drying herbaceous stem stem of Schrenk et C.A.Mey. or ephedra equisetina Ephedra equisetina Bge..Autumn taps green Herbaceous stem stem, dry.Nature and flavor are pungent, slight bitter, temperature.Channel tropism return lung, bladder meridian.Major function sweating cold dispelling, freeings lung and relieving asthma, Li Shui disappears It is swollen.It is uncomfortable in chest to breath with cough for anemofrigid cold, geomantic omen edema；Bronchial asthma.Herba ephedrae moistening lung to arrest cough.It is chiefly used in table disease to have solved, gas It breathes with cough and coughs.

The root bark of tree peony: for the dry root skin of ranunculaceae peony Paeonia suffruticosa Andr..Autumn excavates root Portion removes radicula, strips root skin, dry.It is bitter in taste, pungent, it is slightly cold.Channel tropism return heart, liver and kidney channel.Major function clearing heat and cooling blood, it is living Blood stagnation resolvation.For febrile virulent maculae, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, amenorrhea and algomenorrhea, carbuncle sore tumefacting virus, the pain of injury caused by falling and tumbling.

Radix scrophulariae: for the root of Scrophulariaceae herbaceos perennial radix scrophulariae, main product is in Zhejiang, Sichuan, Hubei and other places.Alias: member Ginseng, Zhejiang radix scrophulariae, black ginseng, Wu Yuancan.Bitter is salty.Cold nature.It is nontoxic.The major functions: warm heat disease heat and ying blood, body heat, polydipsia, tongue it is deep red, Macular eruption, hectic fever due to yin labor is coughed, the dysphoria not puckery dim-sighted, abscess of throat of awake, Tianjin hinder constipation, mesh, scrofula subcutaneous nodule, skin sore.

Radix Glycyrrhizae: for glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza The dry root of inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L..Spring, the excavation of two season of autumn, fibrous root is removed, is shone It is dry.Nature and flavor sweet and neutral.Channel tropism return heart, lung, spleen, stomach meridian.Major function is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, Coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, Alleviate drug toxicity, strong.

The root of Dahurain angelica: for umbellate form section the plant root of Dahurain angelica Angelica dahurica (Fisch.ex Hoffm.) Benth.et Or Radix angelicae dahuricae Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f. The dry root of Hook.f.var.formosana (Boiss.) Shan et Yuan.Excavated when leaf Huang between summer, autumn, remove fibrous root and Silt, sun drying or low temperature drying.Nature and flavor are acrid in flavour and warm in nature.Channel tropism returns stomach, large intestine, lung channel.The dehumidifying of major function relieve heat, sensible analgesic disappear Swollen apocenosis.For cold headache, pain in the supra-orbital bone, nasal obstruction, nasosinusitis, toothache, leukorrhea, sore swell and ache curative.

Exocarpium Citri Rubrum: for rutaceae Huazhou tangerine Citrus grandis Osbeck var.tomentosa Hort. or tangerine Citrus reticulata Blanco and its drying outside rind of variety.It harvests, uses after time of the year when autumn changes into winter fruit maturation Knife cuts lower exocarp, dries or dries in the shade.Nature and flavor are pungent, bitter, temperature.Channel tropism return lung, the spleen channel.Major function cold dispelling, eliminating dampness, sharp gas disappear Phlegm.For cough due to wind-cold evil, larynx is itched abundant expectoration, and dyspepsia is got sick from drinking too much wine, and evil of vomitting ruffian is bored.

Gypsum: for Sulfates mineral anhydrite race gypsum, the main (CaSO containing hydrous calcium sulfate₄·2H₂O), after excavation, remove Remove silt and miscellaneous stone.Nature and flavor are sweet, pungent, Great Cold.Channel tropism attaches to the lung and stomach meridians.Major function clearing heat-fire, relieving restlessness are quenched the thirst.For exogenous disease Pyreticosis, hyperpyrexia polydipsia, dyspnea and cough due to lung-heat, stomach fire Kang Sheng have a headache, toothache.

Radix Angelicae Sinensis: for the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.The excavation of autumn end, Fibrous root and silt are removed, after moisture slightly evaporates, is bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.Nature and flavor sweet, acrid, warm.Channel tropism Return liver, the heart, the spleen channel.Major function replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels.For blood deficiency chlorosis, dizziness palpitaition, menstruation is not It adjusts, amenorrhea and algomenorrhea, asthenia cold abdominalgia, dry constipation of intestines, rheumatic arthralgia, injury from falling down, ulcer sores.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine blood circulation.For Amenorrhea and algomenorrhea, rheumatic arthralgia, injury from falling down.

Pueraria lobata: for legume pueraria lobata Pueraria lobata (Willd.) Ohwi or sweet kudzu Pueraria The dry root of thomsonii Benth..Nature and flavor are sweet, pungent, cool.Channel tropism returns spleen, stomach meridian.Major function expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid, thoroughly Rash, Shengyang Zhixie.It is thirsty for fever caused by exogenous pathogens headache, stiff nape and back, it quenches one's thirst, measles without adequate eruption, hot dysentery, diarrhea；Hypertension neck Strong pain.

White ginseng: being a kind of ginseng, in the product of processing of Panax ginseng, the various processing in addition to red ginseng, such as sun-dried ginseng, white sugar Ginseng, suncured white ginseng root etc., commonly referred to collectively as white ginseng, nature and flavor are sweet in flavor, slight bitter, slightly warm in nature.Channel tropism is return lung, the spleen channel.White ginseng has following Effect: it reinforces vital energy: being suitable for vigour and collapse.It reinforces the spleen to benefit the lung: spleen, Lung Qi deficiency can be controlled.It promotes the production of body fluid to quench thirst: for injury thirst, quenching one's thirst. Calm the nerves and increase intelligence: curing mainly confused and worried caused by insufficiency of vital energy and blood, insomnia forgetfulness, often matches heart-nourishing tranquilizer.

The tuber of pinellia: for the dry tuber of aroid tuber of pinellia Pinellia ternata (Thunb.) Breit..Summer, autumn The excavation of two seasons, is cleaned, and is removed crust and fibrous root, is dried.Nature and flavor are acrid in flavour and warm in nature；It is toxic.Channel tropism returns spleen, stomach, lung channel.Major function is dry Humidifying phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest Gastral cavity ruffian is bored, globus hysteriocus；It is raw to use controlling outward carbuncle swells subcutaneous nodule.Pinellia is chiefly used in stopping nausea and vomiting by lowering the adverse flow of QI.

The root of purple-flowered peucedanum: for umbelliferae RADIX PEUCEDANI Peucedanum praeruptorum Dunn or RADIX PEUCEDANI The dry root of Peucedanum decursivum Maxim..It is bitter in taste, pungent, it is slightly cold.Channel tropism is distributed in lung channel.Major function relieve heat is clear Heat, lowering the adverse-rising QI to resolve phlegm.For cough due to wind-heat evil's abundant expectoration, phlegm heat panting is full, cough up phlegm yellow thick.

The flower bud of lily magnolia: belong to Magnoliacea plant, be Y biondii(Pamp)D.L.Fu (Magnolia biondii Pamp.), yulan (Magnolia Denudata Desr.) or sprenger magnolia bark (Magnolia sprengeri Pamp.) dry flower.The pungent scattered temperature of the flower bud of lily magnolia is logical, returns Lung, stomach meridian, have the effect of expelling cold, eliminating, expelling wind and promoting the restoration of consciousness, cure mainly anemofrigid cold, nasal obstruction, nasosinusitis.

Radix scutellariae: for the dry root of Lamiaceae plant radix scutellariae Scutellaria baicalensis Georgi.Spring, Qiu Erji Excavation removes fibrous root and silt, hits rough bark after solarization, dry.It is bitter in taste, it trembles with fear.Channel tropism return lung, gallbladder, spleen, large intestine, small intestinl channel.Function Heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention can be cured mainly.For damp-warm syndrome, heat temperature chest tightness and emesis, damp and hot feeling of fullness, dysentery, jaundice, lung Heat cough, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, threatened abortion.

Embodiment according to the present invention, the present invention has the advantage that

The typhoid fever theory and warm the clear for purport of school that the traditional chinese medicine composition of the invention is dissipated with pungent-warm table, it is each to merge miscellaneous diseases The anti-relieve heat stomach function regulating to cure cold of family and qi-restoratives table are dissipated and are seted forth one's views, and fully demonstrating the warm disease on " business is on the ground for the treatment of the location first where the pathogens havn't intruded yet ", both disease is preapred for an unfavorable turn of events Thinking.The embodiment of the present invention uses pure plant medicinal material, mixes through scientific compatibility, each raw material component through dialectical compatibility, With relieving exterior syndrome and dispelling cold, expelling wind and promoting the restoration of consciousness, heat-clearing and damp-drying drug, the effect of purging fire for removing toxin, verified through clinical application for many years, be suitable for prevention or Treatment common cold and influenza, especially head body ache, more tears of panting, cough nasal obstruction, generate heat it is thirsty, cease hot dry throat or Bitterly and old man, the physically weak easy catching a cold person of child, has significant in efficacy, and medicinal peace has no toxic side effect, safe and reliable advantage.

Specific embodiment

Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.

This part carries out general description to the material and test method that arrive used in present invention test.Although being It realizes many materials used in the object of the invention and operating method is it is known in the art that still the present invention still uses up herein It may detailed description.It will be apparent to those skilled in the art that within a context, if not specified, material therefor of the present invention and behaviour It is well known in the art as method.

Embodiment 1

The Chinese medicine composition of the prevention of the present embodiment or treatment flu include: 70 grams of perilla leaf, 37 grams of radix saposhnikoviae, 20 grams of schizonepeta, 50 grams of Rhizoma Et Radix Notopterygii, 40 grams of Chinese ephedra, 25 grams of the root bark of tree peony, 35 grams of radix scrophulariae, 35 grams of Radix Glycyrrhizae, 30 grams of the root of Dahurain angelica, 25 grams of Exocarpium Citri Rubrum, 35 grams of gypsum, Radix Angelicae Sinensis 20 grams, 10 grams of pueraria lobata, 28 grams of white ginseng, 40 grams of the tuber of pinellia, 10 grams of the root of purple-flowered peucedanum, 31 grams of the flower bud of lily magnolia, 37 grams of radix scutellariae.Above-mentioned each component is put into pot It is interior, add boiling to mention three times, the water that 8 times of raw material gross weight amounts are added for the first time decocts 1.5 hours, and raw material gross weight is added for the second time The water of 8 times of amounts decocts 1 hour, and 5 times of amount water of raw material gross weight are added for the third time and decoct 0.5 hour, decocting liquid merges to stand and sink three times It forms sediment 36 hours, takes supernatant, the clear cream that relative density is 1.2 when being concentrated under reduced pressure into 80 DEG C.

Embodiment 2

The Chinese medicine composition of the prevention of the present embodiment or treatment flu include: 50 grams of perilla leaf, 40 grams of radix saposhnikoviae, 30 grams of schizonepeta, 30 grams of Rhizoma Et Radix Notopterygii, 30 grams of Chinese ephedra, 40 grams of the root bark of tree peony, 20 grams of radix scrophulariae, 30 grams of Radix Glycyrrhizae, 30 grams of the root of Dahurain angelica, 20 grams of Exocarpium Citri Rubrum, 10 grams of gypsum, Radix Angelicae Sinensis 25 grams, 35 grams of pueraria lobata, 20 grams of white ginseng, 40 grams of the tuber of pinellia, 25 grams of the root of purple-flowered peucedanum, 35 grams of the flower bud of lily magnolia, 30 grams of radix scutellariae.Above-mentioned each component is put into pot It is interior, add boiling to mention three times, the water that 8 times of raw material gross weight amounts are added for the first time decocts 2 hours, and raw material gross weight 6 is added for the second time The water of amount decocts 1 hour again, and the amount water decoction 0.5 hour of 4 times of raw material gross weight is added in third time, and decocting liquid merging three times staticly settles 30 hours, supernatant is taken, the clear cream that relative density is 1.15 when being concentrated under reduced pressure into 80 DEG C.

Embodiment 3

The Chinese medicine composition of the prevention of the present embodiment or treatment flu include: 40 grams of perilla leaf, 20 grams of radix saposhnikoviae, 28 grams of schizonepeta, 10 grams of Rhizoma Et Radix Notopterygii, 50 grams of Chinese ephedra, 45 grams of the root bark of tree peony, 40 grams of radix scrophulariae, 15 grams of Radix Glycyrrhizae, 25 grams of the root of Dahurain angelica, 32 grams of Exocarpium Citri Rubrum, 10 grams of gypsum, Radix Angelicae Sinensis 30 grams, 45 grams of pueraria lobata, 45 grams of white ginseng, 50 grams of the tuber of pinellia, 18 grams of the root of purple-flowered peucedanum, 45 grams of the flower bud of lily magnolia, 20 grams of radix scutellariae.Above-mentioned each component is put into pot It is interior, add boiling to mention three times, the water that 10 times of raw material gross weight amounts are added for the first time decocts 1.5 hours, and raw material gross weight is added for the second time The water for measuring 5 times of amounts decocts 1 hour, and third time is added 3 times of amount water of raw material gross weight and decocts 0.5 hour, and decocting liquid, which merges, three times stands Precipitating 20 hours, takes supernatant, the clear cream that relative density is 1.2 when being concentrated under reduced pressure into 80 DEG C.

Embodiment 4

The Chinese medicine composition of the prevention of the present embodiment or treatment flu include: 30 grams of perilla leaf, 58 grams of radix saposhnikoviae, 42 grams of schizonepeta, 20 grams of Rhizoma Et Radix Notopterygii, 20 grams of Chinese ephedra, 37 grams of the root bark of tree peony, 10 grams of radix scrophulariae, 50 grams of Radix Glycyrrhizae, 48 grams of the root of Dahurain angelica, 10 grams of Exocarpium Citri Rubrum, 28 grams of gypsum, Radix Angelicae Sinensis 42 grams, 20 grams of pueraria lobata, 10 grams of white ginseng, 30 grams of the tuber of pinellia, 30 grams of the root of purple-flowered peucedanum, 20 grams of the flower bud of lily magnolia, 28 grams of radix scutellariae.Above-mentioned each component is put into pot It is interior, add boiling to mention three times, the water that 8 times of raw material gross weight amounts are added for the first time decocts 2 hours, and raw material gross weight 6 is added for the second time The water of amount decocts 1.5 hours again, and the amount water decoction 1 hour of 5 times of raw material gross weight is added in third time, and decocting liquid merging three times staticly settles 30 hours, supernatant is taken, the clear cream that relative density is 1.15 when being concentrated under reduced pressure into 80 DEG C.

Embodiment 5

The Chinese medicine composition of the prevention of the present embodiment or treatment flu include: 80 grams of perilla leaf, 40 grams of radix saposhnikoviae, 50 grams of schizonepeta, 45 grams of Rhizoma Et Radix Notopterygii, 30 grams of Chinese ephedra, 30 grams of the root bark of tree peony, 50 grams of radix scrophulariae, 20 grams of Radix Glycyrrhizae, 40 grams of the root of Dahurain angelica, 40 grams of Exocarpium Citri Rubrum, 48 grams of gypsum, Radix Angelicae Sinensis 50 grams, 30 grams of pueraria lobata, 50 grams of white ginseng, 35 grams of the tuber of pinellia, 50 grams of the root of purple-flowered peucedanum, 48 grams of the flower bud of lily magnolia, 50 grams of radix scutellariae.Above-mentioned each component is put into pot It is interior, add boiling to mention three times, the water that 10 times of raw material gross weight amounts are added for the first time decocts 1.5 hours, and raw material gross weight 6 is added for the second time The water of amount decocts 1.5 hours again, and the amount water decoction 1 hour of 4 times of raw material gross weight is added in third time, and decocting liquid merging three times staticly settles 24 hours, supernatant is taken, the clear cream that relative density is 1.1 when being concentrated under reduced pressure into 80 DEG C.

Embodiment 6

Appropriate amount of starch is added in any obtained clear cream of Example 1-5, mixes, directly pours into capsule, that is, capsule is made Agent.

Embodiment 7

Any obtained clear cream of Example 1-5, is added appropriate calcium monohydrogen phosphate, carboxyrnethyl starch sodium and magnesium stearate, mixes Even, tablet is made in tabletting.

Embodiment 8

Appropriate amount of starch is added in any obtained clear cream of Example 1-5, mixes, adds proper honey, add water general Ball, it is dry, that is, pill is made.

Embodiment 9

Any obtained clear cream of Example 1-5, is added appropriate dextrin, sucrose, mixes, particle is made, that is, be made Granula.

Comparative example 1

The prevention of this comparative example or the Chinese medicine composition for the treatment of flu and the difference of embodiment 1 are only that: using equivalent Ginger replaces perilla leaf.

Comparative example 2

The prevention of this comparative example or the Chinese medicine composition for the treatment of flu and the difference of embodiment 1 are only that: using equivalent Bulbus Allii Fistulosi replaces the flower bud of lily magnolia.

Test case

(1) toxicity test

Healthy BALB/c mouse (female, fifty-fifty, the weight 18-22g of hero) is taken, is randomly divided into control group and test group, every group each 20, control group: normal raising.Test group: 12h is deprived of food but not water before medication, and gastric infusion amount is 50g/kgbw, is equivalent to Adult clinical daily dosage 500 times (quantity be 60kg adult 2 times a day, each 3g).Conventinal breeding is carried out after administration.? In the 14d observation period, the mouse fur of control group and test group is smooth, appearance, behavior, diet, activity, secretion, excreta Situations such as be showed no exception, without dead mouse, and after being administered, 2 groups of mouse weights weight gain comparing differences are not statistically significant.

The result shows that: the Chinese medicine composition of the embodiment of the present invention does not have apparent toxic side effect.

(2) clinical test

1, general information

160 cold patients accepted for medical treatment during in May, -2018 in May, 2013 are chosen as research object, to all patients Data analyzed, wherein male 85, women 75；Common cold 53 as caused by rhinovirus, coronavirus etc., Influenza 107 as caused by influenza virus；The range of age 3-60 years old, average age (35.2 ± 4.8) year, course of disease 2-8 It, average (4.6 ± 1.3) day, mean body temperature (38.5 ± 1.6) DEG C.All patients are randomly divided into test group and control 1-3 Group, every group each 40.Two groups of patients are in basic documents comparing differences such as gender, flu type, age, the course of disease, body temperature without statistics It learns meaning (P > 0.05), is comparable.The content and purpose of selected patient or this clear research of its family members, and voluntarily participate in Research, and sign informed consent form.

2, treatment method

Test group: Chinese medicine composition made from oral embodiment 2, application method: 3 grams every time, 3 times/day.

Compare 1-2 group: Chinese medicine composition made from oral contrast example 1-2 respectively, application method: 3 grams every time, 3 times/day.

It compares 3 groups: taking orally clearing heat and detoxicating particle, 2 bags/time, 3 times a day.

During treatment, all patients is enjoined to drink water, the medication same day avoids Chilled Drinking Water and bathing, avoids repeating to catch a cold more.

3, curative effect determinate standard

Curative effect determinate standard is referring to " flu and influenza diagnosis and curative effect judging standard "

Recovery from illness: in medication 24 hours, whole body and local cardinal symptom such as generate heat, runny nose whole recession, and body temperature is down to Normally.

Effective: in medication 24 hours, cardinal symptom is such as generated heat, runny nose subsides substantially for whole body and part, and body temperature is down to Normally.

It is effective: in medication 24~48 hours, whole body and local cardinal symptom such as generate heat, runny nose disappears or recession substantially. High fever (39 DEG C or more) patient declines 2 DEG C or more, no longer rise person in body temperature 24 hours.

Invalid: it is invalid for not meeting the above standard person.

4, result

Two groups of Clinical efficacy comparisons the results are shown in Table 1.

Table 1

The result shows that: test group 16 people of recovery from illness, effective 9 people, effective 12 people, invalid 3 people, total effective rate 92.5% are right According to 1 group of 8 people of recovery from illness, effective 11 people, effective 11 people, invalid 10 people, total effective rate 75.0% compares 2 groups of 5 people of recovery from illness, and effective 9 People, effective 13 people, invalid 13 people, total effective rate 67.5%, 3 groups of 9 people of recovery from illness of control, effective 12 people, effective 11 people, invalid 8 People, total effective rate 80.0%, the total effective rate of test group are higher than control 1-3 group, illustrate the Chinese traditional medicine composition of the embodiment of the present invention Object curative effect in terms of preventing or treating flu is better than control group.

Although above having used general explanation and specific embodiment, the present invention is described in detail, at this On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore, These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.

Claims

1. the Chinese medicine composition of a kind of prevention or treatment flu, which is characterized in that be made of each component of following parts by weight: Soviet Union 3-8 parts of leaf, 2-6 parts of radix saposhnikoviae, 2-5 parts of schizonepeta, 1-5 parts of Rhizoma Et Radix Notopterygii, 1-5 parts of Chinese ephedra, 2-5 parts of the root bark of tree peony, 1-5 parts of radix scrophulariae, Radix Glycyrrhizae 1-5 Part, 2-5 parts of the root of Dahurain angelica, 1-4 parts of Exocarpium Citri Rubrum, 1-5 parts of gypsum, 2-5 parts of Radix Angelicae Sinensis, 1-5 parts of pueraria lobata, 1-5 parts of white ginseng, 3-5 parts of the tuber of pinellia, the root of purple-flowered peucedanum 1-5 parts, 2-5 parts of the flower bud of lily magnolia, 2-5 parts of radix scutellariae.

2. the Chinese medicine composition of prevention according to claim 1 or treatment flu, which is characterized in that by following parts by weight Each component be made: 5 parts of perilla leaf, radix saposhnikoviae 4 parts, 3 parts of schizonepeta, 3 parts of Rhizoma Et Radix Notopterygii, 3 parts of Chinese ephedra, 4 parts of the root bark of tree peony, 2 parts of radix scrophulariae, 3 parts of Radix Glycyrrhizae, 3 parts of the root of Dahurain angelica, 2 parts of Exocarpium Citri Rubrum, 1 part of gypsum, 2.5 parts of Radix Angelicae Sinensis, 3.5 parts of pueraria lobata, 2 parts of white ginseng, 4 parts of the tuber of pinellia, 2.5 parts of the root of purple-flowered peucedanum, the flower bud of lily magnolia 3.5 Part, 3 parts of radix scutellariae.

3. a kind of preparation method of the Chinese medicine composition of prevention of any of claims 1 or 2 or treatment flu, which is characterized in that The described method includes:

Each raw material is put into pot, boiling is added to mention three times, it is small that 8-10 times of the raw material gross weight water measured decoction 1.5-2 is added for the first time When, the water that second of 5-8 times of raw material gross weight of addition is measured decocts 1-1.5 hours, and third time is added 3-5 times of raw material gross weight and measures water It decocts 0.5-1 hours, decocting liquid merging three times staticly settles 18-36 hours, takes supernatant, relative density when being concentrated under reduced pressure into 80 DEG C For the clear cream of 1.1-1.2.

4. the preparation method of the Chinese medicine composition of prevention according to claim 3 or treatment flu, which is characterized in that described Method includes:

Each raw material is put into pot, boiling is added to mention three times, for the first time the water decoction of 8 times of raw material gross weight amounts of addition 2 hours, second The water of secondary 6 times of raw material gross weight amounts of addition decocts 1 hour, the amount water decoction 0.5 hour of 4 times of third time addition raw material gross weight, and three Secondary decocting liquid merging staticly settles 30 hours, takes supernatant, and relative density is the clear cream of 1.1-1.2 when being concentrated under reduced pressure into 80 DEG C.

5. the Chinese materia medica preparation of a kind of prevention or treatment flu, which is characterized in that the Chinese materia medica preparation is by as claimed in claim 1 or 2 Chinese medicine composition clinically acceptable dosage form is made with clinically acceptable auxiliary material.

6. Chinese materia medica preparation according to claim 5, which is characterized in that the clinically acceptable dosage form includes capsule Agent, tablet, pill, granule.

7. Chinese medicine composition described in claim 1 is in preparation for treating the application in the drug caught a cold.

8. application according to claim 7, which is characterized in that the flu includes influenza and common cold.