CN109568283A - 一种硝苯地平缓释片及其制备方法 - Google Patents
一种硝苯地平缓释片及其制备方法 Download PDFInfo
- Publication number
- CN109568283A CN109568283A CN201811625100.8A CN201811625100A CN109568283A CN 109568283 A CN109568283 A CN 109568283A CN 201811625100 A CN201811625100 A CN 201811625100A CN 109568283 A CN109568283 A CN 109568283A
- Authority
- CN
- China
- Prior art keywords
- parts
- nifedipine
- sustained release
- release tablets
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811625100.8A CN109568283B (zh) | 2018-12-28 | 2018-12-28 | 一种硝苯地平缓释片及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811625100.8A CN109568283B (zh) | 2018-12-28 | 2018-12-28 | 一种硝苯地平缓释片及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109568283A true CN109568283A (zh) | 2019-04-05 |
CN109568283B CN109568283B (zh) | 2020-08-28 |
Family
ID=65933383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201811625100.8A Active CN109568283B (zh) | 2018-12-28 | 2018-12-28 | 一种硝苯地平缓释片及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109568283B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111643468A (zh) * | 2020-07-28 | 2020-09-11 | 华润双鹤利民药业(济南)有限公司 | 一种硝苯地平缓释制剂及其制备 |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0207638A2 (en) * | 1985-06-04 | 1987-01-07 | Teijin Limited | Sustained-release pharmaceutical preparation |
US5264446A (en) * | 1980-09-09 | 1993-11-23 | Bayer Aktiengesellschaft | Solid medicament formulations containing nifedipine, and processes for their preparation |
US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
WO2004087102A2 (en) * | 2003-03-26 | 2004-10-14 | Teva Pharmaceutical Industries Ltd. | A process for preparing a pharmaceutical active ingredient with high specific surface area |
CN101190207A (zh) * | 2006-11-28 | 2008-06-04 | 广东环球制药有限公司 | 一种硝苯地平缓释片的制备方法 |
US20090104273A1 (en) * | 1999-06-22 | 2009-04-23 | Elan Pharma International Ltd. | Novel nifedipine compositions |
CN104997748A (zh) * | 2015-08-03 | 2015-10-28 | 白强 | 一种治疗高血压急症的硝苯地平缓释片剂及其制备工艺 |
CN105412040A (zh) * | 2015-12-14 | 2016-03-23 | 西南药业股份有限公司 | 一种硝苯地平控释片及其制备方法 |
CN106344531A (zh) * | 2016-10-31 | 2017-01-25 | 浙江为康制药有限公司 | 一种硝苯地平控释片组合物及其制备方法 |
CN108853044A (zh) * | 2018-07-06 | 2018-11-23 | 郑州明泽医药科技有限公司 | 一种硝苯地平缓释片及其制备方法 |
-
2018
- 2018-12-28 CN CN201811625100.8A patent/CN109568283B/zh active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5264446A (en) * | 1980-09-09 | 1993-11-23 | Bayer Aktiengesellschaft | Solid medicament formulations containing nifedipine, and processes for their preparation |
EP0207638A2 (en) * | 1985-06-04 | 1987-01-07 | Teijin Limited | Sustained-release pharmaceutical preparation |
US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
US20090104273A1 (en) * | 1999-06-22 | 2009-04-23 | Elan Pharma International Ltd. | Novel nifedipine compositions |
WO2004087102A2 (en) * | 2003-03-26 | 2004-10-14 | Teva Pharmaceutical Industries Ltd. | A process for preparing a pharmaceutical active ingredient with high specific surface area |
CN101190207A (zh) * | 2006-11-28 | 2008-06-04 | 广东环球制药有限公司 | 一种硝苯地平缓释片的制备方法 |
CN104997748A (zh) * | 2015-08-03 | 2015-10-28 | 白强 | 一种治疗高血压急症的硝苯地平缓释片剂及其制备工艺 |
CN105412040A (zh) * | 2015-12-14 | 2016-03-23 | 西南药业股份有限公司 | 一种硝苯地平控释片及其制备方法 |
CN106344531A (zh) * | 2016-10-31 | 2017-01-25 | 浙江为康制药有限公司 | 一种硝苯地平控释片组合物及其制备方法 |
CN108853044A (zh) * | 2018-07-06 | 2018-11-23 | 郑州明泽医药科技有限公司 | 一种硝苯地平缓释片及其制备方法 |
Non-Patent Citations (2)
Title |
---|
UENO K等: "Dissolution Behavior of Nifedipine Sustained-release Preparations", 《JAPANESE JOURNAL OF HOSPITAL PHARMACY》 * |
刘洁等: "硝苯地平不同粒度对其缓释片剂质量的影响", 《中国药师》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111643468A (zh) * | 2020-07-28 | 2020-09-11 | 华润双鹤利民药业(济南)有限公司 | 一种硝苯地平缓释制剂及其制备 |
Also Published As
Publication number | Publication date |
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CN109568283B (zh) | 2020-08-28 |
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CB03 | Change of inventor or designer information |
Inventor after: Yang Zongji Inventor after: Huang Jianping Inventor after: Huang Lei Inventor after: Yan Xia Inventor after: Li Yuting Inventor after: Zhou Yuanhao Inventor before: Yang Zongji Inventor before: Huang Lei Inventor before: Yan Xia Inventor before: Li Yuting Inventor before: Zhou Yuanhao |
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