CN109528507A - A kind of crystal Face-protecting mask and preparation method thereof - Google Patents
A kind of crystal Face-protecting mask and preparation method thereof Download PDFInfo
- Publication number
- CN109528507A CN109528507A CN201811584521.0A CN201811584521A CN109528507A CN 109528507 A CN109528507 A CN 109528507A CN 201811584521 A CN201811584521 A CN 201811584521A CN 109528507 A CN109528507 A CN 109528507A
- Authority
- CN
- China
- Prior art keywords
- additive amount
- crystal face
- protecting mask
- formula weight
- total formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of crystal Face-protecting masks, by being prepared based on mass percentage: water soluble polymer 1-10%, moisturizer 1-20%, effect agent 0.1-2%, preservative 0.1-0.9%, the water of surplus；The water soluble polymer is one or more of polyvinyl alcohol, polyvinylpyrrolidone, gelatin, agarose, xanthan gum, Chondrus crispus (CHONDRUS CRISPUS), gellan gum, algaroba (CERATONIA SILIQUA) glue, mosanom.The invention also discloses the preparation methods of crystal Face-protecting mask.Crystal Face-protecting mask of the invention have the characteristics that transparent, moisturizing, the red detumescence that disappears, not with surface of a wound adhesion, can load EGF promote wound healing.Preparation method of the invention is without harmful components such as crosslinking agent, initiators；It is not required to freezing crosslinking, production simple production cycle is short；It is not required to cross-linking radiation, crosslinking degree is uniform, and quality is stablized.
Description
Technical field
The present invention relates to a kind of facial masks, and in particular to a kind of crystal Face-protecting mask and preparation method thereof.
Background technique
Current medical beauty treatment is accepted extensively by people, wherein micro-shaping operation, as laser operation, photon delicate skin,
Micropin, water light art etc. have become medical and beauty treatment indispensability project.But the above operation may cause skin wound, redness, very
To leading to inflammation, it is necessary to carry out postoperative period maintenance.Therefore, postoperative reparation product can generally be cooperated to subtract in laser therapy
Light pain, improvement effect, and a kind of crystal Face-protecting mask is provided and is had great importance for the recovery of the surface of a wound.
Summary of the invention
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide a kind of crystal Face-protecting masks, it has
Have transparent, moisturizing, the red detumescence that disappears, not with surface of a wound adhesion, can load EGF promote wound healing the characteristics of.
The second object of the present invention is to provide a kind of preparation method of crystal Face-protecting mask, this method without crosslinking agent,
The harmful components such as initiator；It is not required to freezing crosslinking, production simple production cycle is short；It is not required to cross-linking radiation, crosslinking degree is uniform, matter
Amount is stablized.
An object of the present invention adopts the following technical scheme that realization:
A kind of crystal Face-protecting mask, which is characterized in that by being prepared based on mass percentage: water soluble polymer
Polymer 1-10%, moisturizer 1-20%, effect agent 0.1-2%, preservative 0.2-1%, the water of surplus.
Further, the water soluble polymer be polyvinyl alcohol, polyvinylpyrrolidone, gelatin, agarose,
Xanthan gum, Chondrus crispus (CHONDRUS CRISPUS), gellan gum, algaroba (CERATONIA SILIQUA) glue, mosanom
One or more of.
Further, in the water soluble polymer polyvinyl alcohol additive amount be total formula weight 0.1%-
3%, the additive amount of polyvinylpyrrolidone is the 0.1%-3% of total formula weight, and the additive amount of gelatin is total formula weight
0.1%-2%, the additive amount of agarose are the 0.1%-2% of total formula weight, and the additive amount of xanthan gum is total formula weight
0.1%-2%, the additive amount of Chondrus crispus (CHONDRUS CRISPUS) are the 0.1%-2% of total formula weight, gellan gum
Additive amount be total formula weight 0.1%-2%, the additive amount of algaroba (CERATONIA SILIQUA) glue is formula gross weight
The 0.1%-2% of amount, the additive amount of mosanom are the 0.1%-2% of total formula weight.
Further, the moisturizer is glycerol, butanediol, propylene glycol, xylitol, polyglutamic acid sodium, Sodium Hyaluronate
One or more of.
Further, in the moisturizer glycerol additive amount be the 0.1-15% of total formula weight, butanediol additive amount
For the 0.1-15% of total formula weight, the additive amount of propylene glycol be the 0.1-15% of total formula weight, the additive amount of xylitol is
The addition of the 0.1-2% of total formula weight, the 0.1-2%, Sodium Hyaluronate that the additive amount of polyglutamic acid sodium is total formula weight
Amount is the 0.1-2% of total formula weight.
Further, effect agent is one or both of asiaticosid, dipotassium glycyrrhizinate.
Further, in effect agent asiaticosid additive amount be total formula weight 0.05%-2%, glycyrrhizic acid
The additive amount of dipotassium is the 0.05%-2% of total formula weight.
Further, the preservative is one or both of methyl hydroxybenzoate, sodium benzoate.
Further, the additive amount of methyl hydroxybenzoate is 0.1%-0.4% in the preservative, the additive amount of sodium benzoate is
0.1%-0.5%.
The second object of the present invention adopts the following technical scheme that realization:
A kind of preparation method of crystal Face-protecting mask, which comprises the following steps:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 85-90 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative have been sequentially added
At in the main cooker after heating stepses, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal maintenance
Facial mask.
Further, in forming step, crystal Face-protecting mask is immersed in -1 solution of oligopeptides, carrier crystal maintenance face is obtained
Film.
The beneficial effects of the present invention are:
1, crystal Face-protecting mask of the invention is the gel using water as decentralized medium, is the high water solubility with cross-linked structure
Molecularly Imprinted Polymer and water mixing composition, have the hydrophilic residue and hydrone knot in the water soluble polymer of cross-linked network
It closes, hydrone is connected to netted inside, while cooperating moisturizer, effect agent, preservative, with transparent, moisturizing, disappear red move back
It is swollen, not with surface of a wound adhesion, the advantages of EGF promotes wound healing can be loaded.
2, the preparation method is that obtaining crystal maintenance after the water-soluble polymer solution of heat is directly cooled and shaped
Facial mask, without harmful components such as crosslinking agent, initiators；It is not required to freezing crosslinking, production simple production cycle is short；Irradiation is not required to hand over
Connection, crosslinking degree is uniform, and quality is stablized.
Specific embodiment
In the following, being described further in conjunction with specific embodiment to the present invention, it should be noted that is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.
A kind of crystal Face-protecting mask, by being prepared based on mass percentage: water soluble polymer 1-
10%, moisturizer 1-20%, effect agent 0.1-2%, preservative 0.1-0.9%, the water of surplus.
As the mode that further carries out, the water soluble polymer be polyvinyl alcohol, polyvinylpyrrolidone,
Gelatin, agarose, xanthan gum, Chondrus crispus (CHONDRUS CRISPUS), gellan gum, algaroba (CERATONIA
SILIQUA) one or more of glue, mosanom.
As the mode that further carries out, the additive amount of polyvinyl alcohol is that formula is total in the water soluble polymer
The 0.1%-3% of weight, the additive amount of polyvinylpyrrolidone are the 0.1%-3% of total formula weight, and the additive amount of gelatin is
The 0.1%-2% of total formula weight, the additive amount of agarose are the 0.1%-2% of total formula weight, and the additive amount of xanthan gum is
The 0.1%-2% of total formula weight, the additive amount of Chondrus crispus (CHONDRUS CRISPUS) are total formula weight
0.1%-2%, the additive amount of gellan gum are the 0.1%-2% of total formula weight, algaroba (CERATONIA SILIQUA) glue
Additive amount is the 0.1%-2% of total formula weight, and the additive amount of mosanom is the 0.1%-2% of total formula weight.
As the mode that further carries out, the moisturizer is glycerol, butanediol, propylene glycol, xylitol, polyglutamic acid
One or more of sodium, Sodium Hyaluronate.
As the mode that further carries out, glycerol additive amount is the 0.1-15% of total formula weight, fourth in the moisturizer
The additive amount of glycol is the 0.1-15% of total formula weight, the additive amount of propylene glycol is the 0.1-15% of total formula weight, xylose
The additive amount of alcohol is the 0.1-2% of total formula weight, the additive amount of polyglutamic acid sodium is the 0.1-2% of total formula weight, transparent
The additive amount of matter acid sodium is the 0.1-2% of total formula weight.
As the mode that further carries out, effect agent is one or both of asiaticosid, dipotassium glycyrrhizinate.
As the mode that further carries out, the additive amount of asiaticosid is total formula weight in effect agent
0.05%-2%, dipotassium glycyrrhizinate additive amount be total formula weight 0.05%-2%.
As the mode that further carries out, the preservative is one or both of methyl hydroxybenzoate, sodium benzoate.
As the mode that further carries out, the additive amount of methyl hydroxybenzoate is 0.1%-0.4%, benzoic acid in the preservative
The additive amount of sodium is 0.1%-0.5%.
A kind of preparation method of crystal Face-protecting mask, comprising the following steps:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 85-90 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative have been sequentially added
At in the main cooker after heating stepses, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal maintenance
Facial mask.
As the mode that further carries out, in forming step, crystal Face-protecting mask is immersed oligopeptides -1, and (also referred to as epidermis is raw
The long factor, referred to as EGF) in solution, obtain carrier crystal Face-protecting mask.Cross-linked network in crystal Face-protecting mask is uniform
Oligopeptides -1 is absorbed, crystal Face-protecting mask becomes the carrier crystal Face-protecting mask of oligopeptides -1, which can accelerate
Wound healing.
It is specific embodiment of the present invention below, used raw material, equipment etc. remove special limit in the following embodiments
It can be obtained by buying pattern outside fixed.
Embodiment 1:
A kind of crystal Face-protecting mask, by being prepared based on mass percentage:
Water soluble polymer 10%, wherein the additive amount of polyvinyl alcohol be 3%, polyvinylpyrrolidone 2%,
The additive amount of gelatin is 1%, and the additive amount of agarose is 1%, and the additive amount of Chondrus crispus (CHONDRUS CRISPUS) is
2%, the additive amount of gellan gum is 0.5%, and the additive amount of algaroba (CERATONIA SILIQUA) glue is 0.5%.
Moisturizer 20%, wherein the additive amount of glycerol is 2%, butanediol additive amount is 2%, propylene glycol additive amount is
15%, the additive amount of xylitol is 0.5%, polyglutamic acid sodium additive amount is 0.5%.
Effect agent 0.1%, wherein the additive amount of asiaticosid is 0.05%, the additive amount of dipotassium glycyrrhizinate is 0.05%
Preservative 0.2%, wherein methyl hydroxybenzoate additive amount is 0.1%, sodium benzoate additive amount is 0.1%.
Surplus is purified water.
A kind of preparation method of crystal Face-protecting mask, comprising the following steps:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 85 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative have been sequentially added
At in the main cooker after heating stepses, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal maintenance
Facial mask；Then crystal Face-protecting mask is immersed in the EGF solution that concentration is 0.1% 1 hour, obtains carrier crystal Face-protecting mask.
Solvent in the EGF solution is purified water.
Embodiment 2:
A kind of crystal Face-protecting mask, by being prepared based on mass percentage:
Water soluble polymer 2%, wherein the additive amount of polyvinyl alcohol is 0.1%, polyvinylpyrrolidone
0.1%, the additive amount of gelatin is 0.2%, and the additive amount of agarose is 0.2%, Chondrus crispus (CHONDRUS CRISPUS)
Additive amount be 0.8%, the additive amount of gellan gum is 0.3%, and the additive amount of algaroba (CERATONIA SILIQUA) glue is
0.3%.
Moisturizer 1%, wherein the additive amount of propylene glycol is 1%.
Effect agent 2%, wherein the additive amount of asiaticosid is 1%, the additive amount of dipotassium glycyrrhizinate is 1%
Preservative 0.9%, wherein methyl hydroxybenzoate additive amount is 0.4%, sodium benzoate additive amount is 0.5%.
Surplus is purified water.
A kind of preparation method of crystal Face-protecting mask, comprising the following steps:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 88 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative have been sequentially added
At in the main cooker after heating stepses, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal maintenance
Facial mask；Then crystal Face-protecting mask is immersed in the EGF solution that concentration is 0.1% 1 hour, obtains carrier crystal Face-protecting mask.
Solvent in the EGF solution is purified water.
Embodiment 3:
A kind of crystal Face-protecting mask, by being prepared based on mass percentage:
Water soluble polymer 5%, wherein the additive amount of polyvinyl alcohol is adding for 0.5%, polyvinylpyrrolidone
Dosage is 0.5%, and the additive amount of gelatin is 0.2%, and the additive amount of agarose is 0.2%, Chondrus crispus (CHONDRUS
CRISPUS additive amount) is 1.2%, and the additive amount of gellan gum is 0.2%, and algaroba (CERATONIA SILIQUA) glue adds
Dosage is 0.6%.
Moisturizer 10%, wherein the additive amount of glycerol is 2%, the additive amount of butanediol is 2%, the additive amount of propylene glycol
Additive amount for 5%, xylitol is 0.5%, the additive amount of polyglutamic acid sodium is 0.5%.
Effect agent 1%, wherein the additive amount of asiaticosid is 0.5%, the additive amount of dipotassium glycyrrhizinate is 0.5%
Preservative 0.5%, wherein the additive amount of methyl hydroxybenzoate is 0.25%, the additive amount of sodium benzoate is 0.25%.
Surplus is purified water.
A kind of preparation method of crystal Face-protecting mask, comprising the following steps:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 90 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative have been sequentially added
At in the main cooker after heating stepses, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal maintenance
Facial mask；Then crystal Face-protecting mask is immersed in the EGF solution that concentration is 0.1% 1 hour, obtains carrier crystal Face-protecting mask.
Solvent in the EGF solution is purified water.
Comparative example 1:
The characteristics of this comparative example, is: on the basis of embodiment 1, not adding moisturizer.It is other same as Example 1.
Comparative example 2:
The characteristics of this comparative example, is: on the basis of embodiment 2, not adding effect agent.It is other same as Example 2.
Comparative example 3:
The characteristics of this comparative example, is: on the basis of embodiment 3, the EGF solution that concentration is 0.1% being changed to purified water.
It is other same as Example 3.
One, crystal Face-protecting mask transparency is tested:
Human eyesight is most sensitive to the light of 550nm, therefore crystal Face-protecting mask can reflect in the transmitance of 550nm wavelength
The transparency of material out.Using ultraviolet specrophotometer, using air as blank group, measurement 3 sample of embodiment 1- embodiment exists
The absorption of 550nm range, sampling three times, take its average value.Test result is as follows table 1:
Table 1
| Sample | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Transmittance (550nm) | 96% | 98% | 97% |
As can be seen from Table 1, the crystal Face-protecting mask transmittance maximum that embodiment 1- embodiment 3 is prepared can reach
98%, be conducive to directly observe wound, avoiding the need for unlocking dressing could observe, unnecessary to wound bring during release
Wound or infection.
Two, skin moisturizing degree is tested:
Skin moisturizing degree is tested with moisture of skin tester, under testing procedure is:
It is tested under normal room temperature conditions (temperature is 25 DEG C or so, relative humidity 40%-60%), test is commented
Minute mark standard such as the following table 2:
Table 2
Select 5 ages for 35 years old hereinafter, the women of health is as tester, test equipment is moisture of skin survey
Instrument is tried, experiment position is face markers test area, and every place's test area is 5 × 5cm2, test specimen outer dimension length, width and height
For 6cm × 6cm × 0.3cm.Sit quietly in constant environment 0.5h, 1h, 4h of subject is measured.1-3 testers point
The crystal Face-protecting mask sample that Dui Ying embodiment 1- embodiment 3 is not used to prepare, as test group 1- test group 3；4th famous person
The crystal Face-protecting mask sample prepared using comparative example 1 of member, as a control group 1；5th personnel use hospital gauze as pair
According to group 2.
1. before test, subject needs unification to clean face with clear water；
2. probe vertical is attached to skin (remembeing all indentation shells that test is popped one's head in), hears prompt tone in test position
It is readable data after sound；
3. apply crystal Face-protecting mask in specifying part, when 0.5h, 1h, 2h, measures respectively
4. being completed, test probe is cleaned with the soft cloth or tissue paper of being stained with alcohol, and cover skull.
Test result see the table below 3.
Table 3
As can be seen from Table 3, the moistening effect of test group 1- test group 3 is better than control group 1, illustrates after adding moisturizing ingredient
Have better moistening effect；Test group 1- test group 3 and control group 2 compare, and illustrate crystal Face-protecting mask of the invention than doctor
There is better moistening effect with gauze, moist environment can be provided for wound, accelerates wound healing.
Three, red detumescence test is moved back:
Selection 25 just terminates medical and beauty treatment operation, postoperative to have significantly if the women of water light art is as tester
Wound face is randomly divided into 5 groups, and 1-3 group personnel respectively correspond the crystal maintenance face that deposited embodiment 1- embodiment 3 is produced
Film is as test group 1- test group 3；4th group of personnel apply crystal Face-protecting mask that comparative example 2 is produced as a control group 1；5th group
Personnel apply hospital gauze as a control group 2.Start to apply within postoperative 30 minutes, 4 hours observation test effects after applying, finding result is seen below
Table 4.
Test index: without red and swollen phenomenon；It is slight red and swollen；It is obvious red and swollen；
Test environment: indoor environment；Without sunburst or light direct projection；20-25 DEG C of environment temperature；Relative humidity is
40%-60%；
Table 4
As can be seen from Table 4, test group 1- test group 3 moves back red detumescence effect better than control group 1, illustrates to add functional component
Has the effect of preferable relieving swelling and reddness of eye.Test group 1- test group 3 and control group 2 compare, and illustrate crystal maintenance face of the invention
It is more preferable that film than hospital gauze moves back red detumescence effect.
Four, the test of maintenance wound and the test of growth factor supporting effect:
Selection 25 just terminates medical and beauty treatment operation, postoperative to have significantly if the women of water light art is as tester
Wound face is randomly divided into 5 groups, and 1-3 group personnel respectively correspond the crystal maintenance that deposited embodiment 1- embodiment 3 is produced
Facial mask is as test group 1- test group 3；4th group of personnel apply crystal Face-protecting mask that comparative example 3 is produced as a control group 1；5th
Group personnel apply hospital gauze as a control group 2.It applies daily 1 time, totally 7 days, observes test effect, finding result see the table below 5.
Test index: there is no wound face；Shallower wound face；Apparent wound face；
Test environment: indoor environment；Without sunburst or light direct projection；20-25 DEG C of environment temperature；Relative humidity is
40%-60%；
Table 5
As can be seen from Table 5,3 maintenance surface of a wound effect of test group 1- test group is better than control group 2, illustrates crystal of the invention
Face-protecting mask can make wound healing, stronger than hospital gauze to the facilitation of wound healing.3 maintenance of test group 1- test group
Surface of a wound effect is better than control group 1, illustrates that crystal Face-protecting mask of the invention can load EGF, can accelerate wound healing fast after load
Degree.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of crystal Face-protecting mask, which is characterized in that by being prepared based on mass percentage: water soluble polymer is poly-
Close object 1-10%, moisturizer 1-20%, effect agent 0.1-2%, preservative 0.2-1%, the water of surplus.
2. crystal Face-protecting mask as described in claim 1, which is characterized in that the water soluble polymer is polyethylene
Alcohol, polyvinylpyrrolidone, gelatin, agarose, xanthan gum, Chondrus crispus, gellan gum, algaroba glue, one in mosanom
Kind is two or more.
3. crystal Face-protecting mask as claimed in claim 2, which is characterized in that polyethylene in the water soluble polymer
The additive amount of alcohol is the 0.1%-3% of total formula weight, and the additive amount of polyvinylpyrrolidone is the 0.1%- of total formula weight
3%, the additive amount of gelatin is the 0.1%-2% of total formula weight, and the additive amount of agarose is the 0.1%- of total formula weight
2%, the additive amount of xanthan gum is the 0.1%-2% of total formula weight, and the additive amount of Chondrus crispus is total formula weight
0.1%-2%, the additive amount of gellan gum are the 0.1%-2% of total formula weight, and the additive amount of algaroba glue is total formula weight
0.1%-2%, the additive amount of mosanom is the 0.1%-2% of total formula weight.
4. crystal Face-protecting mask as described in claim 1, which is characterized in that the moisturizer is glycerol, butanediol, the third two
One or more of alcohol, xylitol, polyglutamic acid sodium, Sodium Hyaluronate.
5. crystal Face-protecting mask as claimed in claim 4, which is characterized in that glycerol additive amount is that formula is total in the moisturizer
The 0.1-15% of weight, the additive amount of butanediol are the 0.1-15% of total formula weight, the additive amount of propylene glycol is formula gross weight
The 0.1-15% of amount, the additive amount of xylitol are the 0.1-2% of total formula weight, the additive amount of polyglutamic acid sodium is formula gross weight
The 0.1-2% of amount, the 0.1-2% that the additive amount of Sodium Hyaluronate is total formula weight.
6. crystal Face-protecting mask as described in claim 1, which is characterized in that effect agent is asiaticosid, glycyrrhizic acid two
One or both of potassium；The preservative is one or both of methyl hydroxybenzoate, sodium benzoate.
7. crystal Face-protecting mask as claimed in claim 6, which is characterized in that the additive amount of asiaticosid is in effect agent
The 0.05%-2% of total formula weight, the 0.05%-2% that the additive amount of dipotassium glycyrrhizinate is total formula weight.
8. crystal Face-protecting mask as claimed in claim 6, which is characterized in that the additive amount of methyl hydroxybenzoate is in the preservative
0.1%-0.4%, sodium benzoate additive amount be 0.1%-0.5%.
9. a kind of preparation method of the crystal Face-protecting mask as described in claim 1-8 any one, which is characterized in that including with
Lower step:
Heating stepses: the water of formula ratio is added in main cooker, is heated to 85-90 DEG C；
Dissolving step: the water soluble polymer of formula ratio, moisturizer, effect agent, preservative are sequentially added into completion and added
In main cooker after hot step, dissolution is stirred evenly, obtains crystal Face-protecting mask solution；
Forming step: crystal Face-protecting mask solution is poured into mold, and after being cooled to 40 DEG C, molding obtains crystal Face-protecting mask.
10. the preparation method of crystal Face-protecting mask as claimed in claim 9, which is characterized in that in forming step, crystal is repaired
Mask film immerses in -1 solution of oligopeptides, obtains carrier crystal Face-protecting mask.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811584521.0A CN109528507A (en) | 2018-12-24 | 2018-12-24 | A kind of crystal Face-protecting mask and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811584521.0A CN109528507A (en) | 2018-12-24 | 2018-12-24 | A kind of crystal Face-protecting mask and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109528507A true CN109528507A (en) | 2019-03-29 |
Family
ID=65857118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811584521.0A Withdrawn CN109528507A (en) | 2018-12-24 | 2018-12-24 | A kind of crystal Face-protecting mask and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109528507A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111388351A (en) * | 2020-05-26 | 2020-07-10 | 上海家化联合股份有限公司 | Thickener composition comprising agarose and xanthan gum |
| CN111437242A (en) * | 2020-05-07 | 2020-07-24 | 江苏华能药业有限公司 | Crystal mask prepared from jellyfish |
| CN112263528A (en) * | 2020-10-26 | 2021-01-26 | 广东美集科技有限公司 | Collagen jelly mask and preparation and use methods thereof |
| CN112294682A (en) * | 2019-07-31 | 2021-02-02 | 太和康美(北京)中医研究院有限公司 | Composition and preparation method and application thereof |
| CN113456541A (en) * | 2020-03-30 | 2021-10-01 | 湖南御家化妆品制造有限公司 | Acne-removing composition, application thereof and acne-removing nursing membrane |
| CN114224750A (en) * | 2022-01-25 | 2022-03-25 | 中森优品(广州)生物科技有限公司 | Focus care ice crystal mask and preparation process thereof |
| CN114246811A (en) * | 2021-09-03 | 2022-03-29 | 太和康美(北京)中医研究院有限公司 | Skin moisturizer with moisturizing effect and preparation method thereof |
| CN114392217A (en) * | 2022-01-25 | 2022-04-26 | 中森优品(广州)生物科技有限公司 | Application method of focus-care ice crystal mask |
-
2018
- 2018-12-24 CN CN201811584521.0A patent/CN109528507A/en not_active Withdrawn
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112294682A (en) * | 2019-07-31 | 2021-02-02 | 太和康美(北京)中医研究院有限公司 | Composition and preparation method and application thereof |
| CN112294682B (en) * | 2019-07-31 | 2022-07-29 | 太和康美(北京)中医研究院有限公司 | Composition and preparation method and application thereof |
| CN113456541A (en) * | 2020-03-30 | 2021-10-01 | 湖南御家化妆品制造有限公司 | Acne-removing composition, application thereof and acne-removing nursing membrane |
| CN111437242A (en) * | 2020-05-07 | 2020-07-24 | 江苏华能药业有限公司 | Crystal mask prepared from jellyfish |
| CN111388351A (en) * | 2020-05-26 | 2020-07-10 | 上海家化联合股份有限公司 | Thickener composition comprising agarose and xanthan gum |
| CN111388351B (en) * | 2020-05-26 | 2022-03-11 | 上海家化联合股份有限公司 | Thickener composition comprising agarose and xanthan gum |
| CN112263528A (en) * | 2020-10-26 | 2021-01-26 | 广东美集科技有限公司 | Collagen jelly mask and preparation and use methods thereof |
| CN114246811A (en) * | 2021-09-03 | 2022-03-29 | 太和康美(北京)中医研究院有限公司 | Skin moisturizer with moisturizing effect and preparation method thereof |
| CN114224750A (en) * | 2022-01-25 | 2022-03-25 | 中森优品(广州)生物科技有限公司 | Focus care ice crystal mask and preparation process thereof |
| CN114392217A (en) * | 2022-01-25 | 2022-04-26 | 中森优品(广州)生物科技有限公司 | Application method of focus-care ice crystal mask |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109528507A (en) | A kind of crystal Face-protecting mask and preparation method thereof | |
| CN105168112A (en) | Anti-wrinkle toner and preparation method thereof | |
| CN111658818A (en) | Medical repair dressing and application thereof | |
| CN105902461A (en) | Essence containing snail mucus extracts and preparation method thereof | |
| CN105797202B (en) | Liquid band-aid and preparation method thereof | |
| CN103705984A (en) | Preparation method and application of collagen scaffold composite bone marrow-derived mesenchymal stem cells (BMSCs) | |
| CN114601771B (en) | Soothing essence and preparation method thereof | |
| CN107375032A (en) | A kind of composition and preparation method for repairing skin barrier | |
| CN112826811A (en) | Medical cold compress gel eye patch and preparation method thereof | |
| WO2019033584A1 (en) | Sunscreen skincare product and preparation method therefor | |
| CN104474577B (en) | A kind of postoperative dressing of laser beautifying and preparation method | |
| CN114891279B (en) | Composite hydrogel and preparation method and application thereof | |
| CN110200988A (en) | A kind of scar repair agent and preparation method thereof | |
| CN102895699A (en) | Preparation method of composite hydrogel dressing for repairing skin injury | |
| CN104225577B (en) | A kind of double course for the treatment of compound cells growth factor hydrogels and preparation method and with application | |
| KR20150033237A (en) | Hydrogel patch for wound healing and monitoring | |
| CN109820801A (en) | A kind of mild repairing type whitening mask and its preparation process | |
| JP2019202996A (en) | COSMETIC COMPOSITION COMPRISING γ-POLYGLUTAMIC ACID AS ACTIVE COMPONENT | |
| CN109966167A (en) | A kind of lip treatment composition and preparation method thereof | |
| CN111714681A (en) | Medical adhesive dressing and preparation method thereof | |
| CN106265719A (en) | A kind of medical heat clearing away anti-bacterial hydrogel eye sticker and preparation method thereof | |
| CN114306125A (en) | Composition containing schizophyllan with different molecular weights as well as preparation method and application thereof | |
| CN113018199A (en) | Multipurpose ice film for repairing epidermis and preparation method thereof | |
| CN104000748A (en) | Medical radiotherapy skin care agent and production technology thereof | |
| CN107519114A (en) | A kind of facial treatment mask and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190329 |