CN107519114A - A kind of facial treatment mask and preparation method thereof - Google Patents
A kind of facial treatment mask and preparation method thereof Download PDFInfo
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- CN107519114A CN107519114A CN201710983834.2A CN201710983834A CN107519114A CN 107519114 A CN107519114 A CN 107519114A CN 201710983834 A CN201710983834 A CN 201710983834A CN 107519114 A CN107519114 A CN 107519114A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
A kind of facial treatment mask and preparation method thereof, it is related to chemistry and daily chemical products field.A kind of facial treatment mask, it is mainly made up of following raw material, the raw material of the facial treatment mask, which is made, includes the first major ingredient, the second major ingredient and auxiliary material, first major ingredient includes the parts by weight of bletilla striata extract 15, second major ingredient includes the parts by weight of epithelical cell growth factor 0.5 2, and auxiliary material includes the parts by weight of glycerine 15, the parts by weight of polyglutamic acid 0.1 1, the parts by weight of hyaluronic acid 0.1 1 and the parts by weight of water 85.2 97.2.It has repair skin, anti-aging, moisten, moisturizing, good film-forming property and it is safe and reliable the characteristics of.
Description
Technical field
The present invention relates to chemistry and daily chemical products field, and more particularly to a kind of facial treatment mask and preparation method thereof.
Background technology
Facial mask market has turned into that China's daily use chemicals industry is fastest-rising one of to segment market at present.The development speed of facial mask it
It is closely bound up with its effect soon.Facial mask can solve 5 big problem of skin simultaneously：Moisturizing, whitening, oil-control, antiallergic sense and anti-aging.
And everyday skincare can not quickly improve skin condition comprehensively often just for subproblem therein.Facial mask is utilized and is covered in
The of short duration time of face, be temporarily isolating the external world air and pollution, improve skin temperature and expansion pore, promote sweat gland secretion with
Metabolism, skin oxygen content is set to increase.Moisture in facial mask penetrates into skin cuticula, it is become soft, increase elasticity；Face
Gumminess composition or powdered absorbent in film can stick dirt, metabolic waste and excessive grease in skin surface and pore
Deng, and it is thoroughly removed.
The content of the invention
It is an object of the invention to provide a kind of facial treatment mask, and it has moisturizing, improves the characteristics of skin elasticity.
Another object of the present invention is to provide a kind of preparation method of facial treatment mask, its technique is simple, and each component is independent
Sterilization treatment is carried out, there is preferable sterilization effect, safe and reliable facial treatment mask can be prepared.
The present invention is solved its technical problem and realized using following technical scheme.
The present invention proposes a kind of facial treatment mask, and it is mainly made up of following raw material, prepares the raw material of the facial treatment mask and includes
First major ingredient, the second major ingredient and auxiliary material, the first major ingredient include bletilla striata extract 1-5 parts by weight, and the second major ingredient includes epidermal cell
Growth factor 0.5-2 parts by weight, auxiliary material include glycerine 1-5 parts by weight, polyglutamic acid 0.1-1 parts by weight, hyaluronic acid 0.1-1 weights
Measure part and water 85.2-97.2 parts by weight.
The present invention also proposes a kind of preparation method of facial treatment mask, including：
The auxiliary material of mixing is sterilized under conditions of temperature is 115-125 DEG C and pressure is 0.07-0.13MPa,
Then it is cooled to 36-42 DEG C；
First major ingredient is sterilized under conditions of temperature is 115-125 DEG C and pressure is 0.07-0.13MPa, so
After be cooled to 36-42 DEG C；
By the solution filtration sterilization of epithelical cell growth factor, then with the first major ingredient after the auxiliary material after cooling and cooling
Mixing.
Facial treatment mask of the embodiment of the present invention and preparation method thereof beneficial effect is：The facial treatment mask of the embodiment of the present invention,
Due to compounded the suitable bletilla striata extract of ratio, epithelical cell growth factor, polyglutamic acid, hyaluronic acid and glycerine and
Water, wherein, bletilla striata extract and epithelical cell growth factor collaboration play excellent senile-resistant efficacy, can smooth tiny wrinkle
Line, skin elasticity is improved, improve dermatoglyph degree；Promote fibroblast synthesis collagen, promote wound healing, repair by
Damage skin.The polyglutamic acid of HMW in facial treatment mask has good film forming, skin sense good.Low molecule amount is saturating simultaneously
Bright matter acid easily penetrates into skin, is brought to skin and continues good performance of keeping humidity.In addition, the glycerine in facial treatment mask also has well
Moistening effect.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase
Product.
A kind of facial treatment mask of the embodiment of the present invention and preparation method thereof is specifically described below.
A kind of facial treatment mask, it is mainly made up of raw material, and raw material includes the first major ingredient, the second major ingredient and auxiliary material, the first master
Material includes bletilla striata extract 1-5 parts by weight, and the second major ingredient includes epithelical cell growth factor 0.5-2 parts by weight, and auxiliary material includes sweet
Oily 1-5 parts by weight, polyglutamic acid 0.1-1 parts by weight, hyaluronic acid 0.1-1 parts by weight and water 85.2-97.2 parts by weight.
Bletilla striata extract and epithelical cell growth factor, bletilla striata extract and epidermal growth have been compounded in facial treatment mask
Factor collaboration plays excellent senile-resistant efficacy, can smooth fine wrinkles, improves skin elasticity, improves dermatoglyph degree；Promote
Enter fibroblast synthesis collagen, promote wound healing, repair impaired skin.
Epithelical cell growth factor, also known as people oligopeptides -1, English name：Epidermal Growth Factor (English letters
Claim EGF).
The polyglutamic acid of HMW in facial treatment mask has good film forming, skin sense good.While low molecule amount
Hyaluronic acid easily penetrates into skin, is brought to skin and continues good performance of keeping humidity.In addition, the glycerine in facial treatment mask is also with good
Good moistening effect.
The facial treatment mask of the embodiment of the present invention, due to compounded the suitable bletilla striata extract of ratio, epidermal growth because
Son, polyglutamic acid, hyaluronic acid and G ＆ W so that the facial treatment mask has good senile-resistant efficacy, can smoothed
Fine wrinkles, skin elasticity is improved, improve dermatoglyph degree；Promote fibroblast synthesis collagen, promote wound healing,
Repair impaired skin.And with the characteristics of moistening effect is good, good film-forming property and skin sense are good.
In an embodiment of the present invention, the bletilla striata extract in facial treatment mask is 2-4 parts by weight, epidermal growth
The factor is 0.8-1.5 parts by weight, and glycerine is 2-4 parts by weight, and polyglutamic acid is 0.2-0.6 parts by weight, hyaluronic acid 0.2-0.8
Parts by weight, water are 88-95 parts by weight.
Further, in some embodiments of the invention, avenabeta glucosan 0.1-0.8 weights are also included in the second major ingredient
Measure part.
Avenabeta glucosan, it is a kind of SNSP with oat endosperm and gluten cell wall be present.It possesses excellent
Different senile-resistant efficacy, fine wrinkles can be smoothed, improve skin elasticity, improve dermatoglyph degree；Straight chain point with uniqueness
Minor structure, impart good Transdermal absorption performance；Promote fibrocyte synthesis collagen, promote wound healing, repair by
Skin is damaged, skin is given and smooth sense of touch is moistened such as silk.
In some embodiments of the invention, avenabeta glucosan is 0.3-0.6 parts by weight.
It should be noted that in an embodiment of the present invention, bletilla striata extract is the water extract of the bletilla striata.
A kind of preparation method of facial treatment mask, it is main to include respectively locating auxiliary material, the first major ingredient and the second major ingredient in advance
Reason.
Wherein, auxiliary material is pre-processed, it is 115-125 DEG C in temperature by the auxiliary material of mixing mainly to include and pressure is
Sterilized under conditions of 0.07-0.13MPa.Further, in some embodiments of the invention, the sterilising temp of auxiliary material is
120-122℃.It should be noted that the auxiliary material of mixing can obtain after being mixed in advance, can also be by directly buying
Mode obtain blended auxiliary material.Further, in some embodiments of the invention, the sterilization time of auxiliary material is 20-
40min.Need auxiliary material being cooled to 36-42 DEG C after sterilizing to auxiliary material.
In addition, the first major ingredient is also required to pre-process, it is main to include the first major ingredient being 115-125 DEG C and pressure in temperature
To be sterilized under conditions of 0.07-0.13MPa.Further, in some embodiments of the invention, the sterilizing of the first major ingredient
Temperature is 118-121 DEG C.Obtained it should be noted that the first major ingredient can be self-control, can also be by way of directly buying
Obtain.I.e. bletilla striata extract can be homemade or directly bought.Further, in some implementations of the present invention
In example, the sterilization time of the first major ingredient is 20-40min.Then need to cool the first major ingredient after sterilizing to the first major ingredient
To 36-42 DEG C.
It is simpler compared to auxiliary material and the first major ingredient, the processing of the second major ingredient.
When comprising only epithelical cell growth factor in the second major ingredient, it is only necessary to which the solution of epithelical cell growth factor is entered
Row filtration sterilization.
When including epithelical cell growth factor and avenabeta glucosan in the second major ingredient, to epithelical cell growth factor
Solution carry out filtration sterilization after mixed with avenabeta glucosan.
By carrying out sterilization treatment respectively step by step to the first major ingredient in facial treatment mask, the second major ingredient and auxiliary material, first
Major ingredient and auxiliary material use high-temp steam sterilizing, and sterilization effect is good.And different components, property is different, is gone out respectively step by step
Bacterium meets the property of each component.
The preparation method of facial treatment mask also include will be degerming after the second major ingredient and the auxiliary material after cooling and the after cooling
One major ingredient mixes.
When the second major ingredient includes epithelical cell growth factor, filtration sterilization is carried out to the solution of epithelical cell growth factor
Mixed afterwards with the first major ingredient after the auxiliary material after cooling and cooling.
When including epithelical cell growth factor and avenabeta glucosan in the second major ingredient, to epithelical cell growth factor
Solution carry out filtration sterilization after mixed with avenabeta glucosan, then again with the first major ingredient after the auxiliary material after cooling and cooling
Mixing.
Further, in an embodiment of the present invention, the second degerming major ingredient and the auxiliary material after cooling and the after cooling
After the mixing of one major ingredient, then carry out sterile filling.Wherein, filling specification is 27mL/ bags.
Embodiments of the invention use aseptic filling technology, have abandoned traditional preservative, reduce the wind for endangering skin
Danger.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 1
Part, the parts by weight of epithelical cell growth factor 1, the parts by weight of avenabeta glucosan 0.5, the parts by weight of glycerine 3, the weight of polyglutamic acid 0.6
Part, the parts by weight of hyaluronic acid 0.5 and the parts by weight of water 85.2.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 121 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 30 minutes, be then cooled to 40 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 121 DEG C, and be 0.1MPa in pressure
Under conditions of keep 30 minutes sterilize, be then cooled to 40 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 2
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 4
Part, the parts by weight of epithelical cell growth factor 1.2, the parts by weight of avenabeta glucosan 0.2, the parts by weight of glycerine 1, the weight of polyglutamic acid 0.3
Measure part, the parts by weight of hyaluronic acid 0.7 and the parts by weight of water 87.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 120 DEG C and pressure be 0.07MPa under conditions of keep sterilizing for 20 minutes, be then cooled to 42 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 120 DEG C, be 0.07MPa in pressure
Under conditions of keep 20 minutes sterilize, be then cooled to 42 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 3
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 5
Part, the parts by weight of epithelical cell growth factor 0.6, the parts by weight of avenabeta glucosan 0.6, the parts by weight of glycerine 2, the weight of polyglutamic acid 0.2
Measure part, the parts by weight of hyaluronic acid 0.3 and the parts by weight of water 90.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 122 DEG C and pressure be 0.13MPa under conditions of keep sterilizing for 40 minutes, be then cooled to 36 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 122 DEG C, be 0.13MPa in pressure
Under conditions of keep 40 minutes sterilize, be then cooled to 36 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 4
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 2
Part, the parts by weight of epithelical cell growth factor 1.5, the parts by weight of avenabeta glucosan 0.1, the parts by weight of glycerine 5, the weight of polyglutamic acid 0.8
Measure part, the parts by weight of hyaluronic acid 0.2 and the parts by weight of water 88.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 115 DEG C and pressure be 0.07MPa under conditions of keep sterilizing for 35 minutes, be then cooled to 38 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 115 DEG C, be 0.07MPa in pressure
Under conditions of keep 35 minutes sterilize, be then cooled to 38 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 5
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 2.5
Measure part, the parts by weight of epithelical cell growth factor 1.8, the parts by weight of avenabeta glucosan 0.8, the parts by weight of glycerine 4, polyglutamic acid 0.4
Parts by weight, the parts by weight of hyaluronic acid 0.1 and the parts by weight of water 97.2.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 118 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 35 minutes, be then cooled to 38 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 118 DEG C, is 0.1MPa's in pressure
Under the conditions of keep 35 minutes sterilize, be then cooled to 38 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 6
The present embodiment provides a kind of facial treatment mask, and it is mainly made up of raw material, raw material include the parts by weight of bletilla striata extract 3,
The parts by weight of epithelical cell growth factor 0.8, the parts by weight of avenabeta glucosan 0.4, the parts by weight of glycerine 4.5, the weight of polyglutamic acid 0.5
Part, the parts by weight of hyaluronic acid 1 and the parts by weight of water 92.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 121 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 30 minutes, be then cooled to 40 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 121 DEG C, is 0.1MPa's in pressure
Under the conditions of keep 30 minutes sterilize, be then cooled to 40 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 7
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 3.5
Measure part, the parts by weight of epithelical cell growth factor 0.5, the parts by weight of avenabeta glucosan 0.3, the parts by weight of glycerine 3.5, polyglutamic acid 1
Parts by weight, the parts by weight of hyaluronic acid 0.4 and the parts by weight of water 95.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 121 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 25 minutes, be then cooled to 40 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 120 DEG C, is 0.1MPa's in pressure
Under the conditions of keep 25 minutes sterilize, be then cooled to 38 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 8
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 1.5
Measure part, the parts by weight of epithelical cell growth factor 2, the parts by weight of avenabeta glucosan 0.7, the parts by weight of glycerine 2.5, polyglutamic acid 0.1
Parts by weight, the parts by weight of hyaluronic acid 0.8 and the parts by weight of water 94.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 121 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 25 minutes, be then cooled to 40 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 120 DEG C, is 0.1MPa's in pressure
Under the conditions of keep 25 minutes sterilize, be then cooled to 38 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after mix with avenabeta glucosan solution, then add into hair
In fermentation tank, stirring 15min is sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Embodiment 9
The present embodiment provides a kind of facial treatment mask, and the raw material for preparing the facial treatment mask includes the weight of bletilla striata extract 3
Part, the parts by weight of epithelical cell growth factor 0.8, the parts by weight of glycerine 4.5, the parts by weight of polyglutamic acid 0.5, the parts by weight of hyaluronic acid 1
And the parts by weight of water 92.
The preparation method of the facial treatment mask, including：
The raw material of above-mentioned parts by weight is weighed, is mixed glycerine, water, polyglutamic acid and hyaluronic acid in fermentation tank, in temperature
Spend for 121 DEG C and pressure be 0.1MPa under conditions of keep sterilizing for 30 minutes, be then cooled to 40 DEG C.
Bletilla striata extract is mended and is attached in material bottle, is put into high-pressure sterilizing pot and is heated to 121 DEG C, is 0.1MPa's in pressure
Under the conditions of keep 30 minutes sterilize, be then cooled to 40 DEG C, then add in fermentation tank and mix.
By epithelical cell growth factor solution it is filtered it is degerming after add in fermentation tank, stirring 15min be sufficiently mixed.
Then the inspection of semifinished product, sterile filling are carried out.Wherein, filling specification is 27mL/ bags.
Comparative example 1
The facial treatment mask of the comparative example is identical with the preparation method of the facial treatment mask of embodiment 1, and it the difference is that only
The raw material proportioning of the facial treatment mask of comparative example 1 is different, and the facial treatment mask of comparative example 1 is mainly made up of raw material, and raw material includes：The bletilla striata
The parts by weight of extract 0.8, the parts by weight of epithelical cell growth factor 0.4, the parts by weight of avenabeta glucosan 0.9, the weight of glycerine 5.2
Part, the parts by weight of polyglutamic acid 0.05, the parts by weight of hyaluronic acid 1.1 and the parts by weight of water 98.
Comparative example 2
The facial treatment mask of the comparative example is identical with the preparation method of the facial treatment mask of embodiment 1, and it the difference is that only
The raw material proportioning of the facial treatment mask of comparative example 2 is different, and the facial treatment mask of comparative example 2 is mainly made up of raw material, and raw material includes：The bletilla striata
The parts by weight of extract 5.2, the parts by weight of epithelical cell growth factor 2.2, the parts by weight of avenabeta glucosan 0.05, the weight of glycerine 0.9
Part, the parts by weight of polyglutamic acid 1.1, the parts by weight of hyaluronic acid 0.08 and the parts by weight of water 83.
Comparative example 3
The facial treatment mask of the comparative example is identical with the preparation method of the facial treatment mask of embodiment 1, and it the difference is that only
The raw material of the facial treatment mask of comparative example 3, proportioning are different, and the facial treatment mask of comparative example 3 is mainly made up of raw material, and raw material includes：In vain
It is the parts by weight of splendid achnatherum extract 5.2, the parts by weight of avenabeta glucosan 0.05, the parts by weight of glycerine 0.9, the parts by weight of polyglutamic acid 1.1, transparent
Matter 0.08 parts by weight of acid and the parts by weight of water 83.
Comparative example 4
The facial treatment mask of the comparative example is identical with the preparation method of the facial treatment mask of embodiment 1, and it the difference is that only
The raw material proportioning of the facial treatment mask of comparative example 4 is different, and the facial treatment mask of comparative example 4 is mainly made up of raw material, and raw material includes：Epidermis
The parts by weight of Porcine HGF 2.2, the parts by weight of avenabeta glucosan 0.05, the parts by weight of glycerine 0.9, the parts by weight of polyglutamic acid 1.1,
The parts by weight of hyaluronic acid 0.08 and the parts by weight of water 83.
Test example 1
Moistening effect is tested:Embodiment 1-9 and comparative example 1-4 facial treatment mask are attached at skin surface, the amount of attaching
It is identical, the change by using the measurement of skin surface humidity tester with the passage moisture-holding capacity of time.Effect is shown as well：Water conservation
Ability increase at least 15%；Effect normally behaves as：Water holding capacity increases 7-15%；The increase of effect difference water holding capacity is less than 7%.
Its result is recorded in table 1.
The moistening effect test of the embodiment 1-9 of table 1 and comparative example 1-4 facial treatment mask
From the results shown in Table 1, the moistening effect of 1-9 of embodiment of the present invention facial treatment mask is all preferable.And with reality
Apply that a 1-9 raw material is identical, but the facial treatment mask moistening effect for matching different comparative example 1-2 is general, illustrates to utilize this hair
The facial treatment mask that the raw material of bright embodiment, proportioning are prepared has more preferable moistening effect.
Test example 2
Skin elasticity is tested：Selection face has mild skin aging to show (drying, microgroove, poor flexibility etc.), and without allergy
The female volunteers of history 220, age are 30-50 year, are randomly divided into 11 groups, every group of 20 people.Use skin elasticity tester pair
20min skin of face is tested after volunteer's progress facial cleansing, determines its skin elasticity.Then each group volunteer distinguishes
The Example 1-9 and comparative example 1-4 pocket facing of facial treatment mask 1 is attached to face, once a day, face is first carried out before attaching facial treatment mask
Portion cleans, and facial treatment mask cleans up after 30min is kept on the face.To volunteer attach facial treatment mask after 3d, 7d, 14d and
20d carries out skin elasticity test, and the testing time is that facial treatment mask is cleaned rear 10min, then calculates the increasing of skin elasticity
Add rate, its result is recorded in table 2.
The skin elasticity test result of table 2
From the results shown in Table 2, in 3d, 7d, 14d and 20d skin elasticity test result, embodiment 1-9 skin
Skin elasticity growth rate be above comparative example 1-2 skin elasticity growth rate, illustrate using the embodiment of the present invention raw material,
Matching the facial treatment mask being prepared has anti-wrinkle of preferably compacting, increases the effect of skin elasticity.In addition, the skin of embodiment 1
The growth rate of skin elasticity of the growth rate higher than comparative example 3-4 of skin elasticity, wherein, epidermal cell life is not contained in comparative example 3
The long factor, bletilla striata extract is not contained in comparative example 4, illustrates that EGF and bletilla striata extract can act synergistically,
Skin elasticity is improved, compacts and wrinkles.
Test example 3
Security test：Safety evaluatio is done to embodiment 1-9 facial treatment mask, specifically, carried out 48 hours with cavy
Animal patch test with evaluate irritability level, wherein, no irritability shows as no erythema and oedema, typically stress sex expression
For slight erythema and oedema, moderate irritability shows as obvious erythema and oedema, and its concrete outcome is recorded in table 3.
The security test of the embodiment 1-9 of table 3 facial treatment mask
From the results shown in Table 3, embodiment 1-9 facial treatment mask is safe and reliable without irritability.
Test example 4
Wound repair is tested：
(1) experimental animal：Select the new zealand rabbit 20 of healthy adult, male and female half and half, animal credit number SCXK
(Zhejiang) 2016-0008, single cage are fed, and are adapted to environment and are raised one week.
(2) test specimen：Embodiment 1-3 and comparative example 3-4 facial treatment mask.
(3) test method
Build rabbit back skin full-thickness defects trauma model：Pre-operative anxiety 12h.The preoperative 1d vulcanized sodium of volume fraction 8%
Rabbit back is lost hair or feathers, exposure 15cm × 10cm skin, the yellow Jackets of rabbit intraperitoneal injection volume fraction 2% during operation
(30mg/kg) is anaesthetized, the tincture of iodine, ethanol disinfection, is spread aseptic operation towel, shoulder blade and ilium is avoided, with special card punch away from ridge
Post 2.0cm bilateral makes the circular surface of a wound each 3, area about 3.14cm2, and about 2.0cm is spaced between surface of a wound edge, cuts off the surface of a wound
Full thickness skin is to deep fascia.Skin holostrome is cut off to deep fascia, i.e. wound modeling success.
Group experiment：Rabbit 20 is only randomly divided into 5 groups, every group 4, male and female half and half.1-5 groups are utilized respectively embodiment 1-
3 and comparative example 3-4 facial treatment mask is treated.1 group of rabbit attaches the facial treatment mask of embodiment 1,2 groups of family in site of injury
Rabbit attaches the facial treatment mask of embodiment 2 in site of injury, and 3 groups of rabbit attaches the facial treatment mask of embodiment 3 in site of injury, 4 groups
Rabbit attaches the facial treatment mask of comparative example 3 in site of injury, and 5 groups of rabbit attaches the facial treatment mask of comparative example 4 in site of injury, daily
Change once, method is identical with dosage, until wound healing.
As a result test：The 5th day after surgery, the 10th day, surface of a wound area is measured with 0.25cm × 0.25cm transparent graph paper,
Surface of a wound area, Wound healing rate=[(original face area-measurement surface of a wound are calculated with Germany's semi-automatic image analyzers of production ASM-68K
Area)/original face area] × 100%, and test wound healing time, its result be recorded in table 4.
The each group wound healing time of table 4 and Wound healing rate
From the results shown in Table 4, wound healing time of the wound healing time of 1-3 groups than 4 groups is averagely advanced by
4.7 days, wound healing time of the wound healing time than 5 groups of 1-3 groups was averagely advanced by 4.2 days, illustrate epidermal cell because
Son and bletilla striata extract can act synergistically, and improve the repair ability to wound.
In summary, the facial treatment mask of the embodiment of the present invention is thin due to having compounded the suitable bletilla striata extract of ratio, epidermis
The intracellular growth factor, polyglutamic acid, hyaluronic acid and G ＆ W, wherein, bletilla striata extract and epithelical cell growth factor association
With excellent senile-resistant efficacy is played, fine wrinkles can be smoothed, improve skin elasticity, improve dermatoglyph degree；Promote into fibre
Smooth muscle cells collagen synthesis albumen is tieed up, promotes wound healing, repairs impaired skin.The polyglutamic acid tool of HMW in facial treatment mask
There are good film forming, skin sense good.The hyaluronic acid of low molecule amount easily penetrates into skin simultaneously, is brought to skin and continues good guarantor
Wet performance.In addition, the glycerine in facial treatment mask also has good moistening effect.
Embodiments described above is part of the embodiment of the present invention, rather than whole embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of facial treatment mask, it is characterised in that it is mainly made up of following raw material, and the raw material of the facial treatment mask is made
Including the first major ingredient, the second major ingredient and auxiliary material, first major ingredient includes bletilla striata extract 1-5 parts by weight, second major ingredient
Including epithelical cell growth factor 0.5-2 parts by weight, the auxiliary material includes glycerine 1-5 parts by weight, polyglutamic acid 0.1-1 weight
Part, hyaluronic acid 0.1-1 parts by weight and water 85.2-97.2 parts by weight.
2. facial treatment mask according to claim 1, it is characterised in that the bletilla striata extract is 2-4 parts by weight, the table
Skin cell growth factor is 0.8-1.5 parts by weight, and the glycerine is 2-4 parts by weight, and the polyglutamic acid is 0.2-0.6 weight
Part, the hyaluronic acid are 0.2-0.8 parts by weight, and the water is 88-95 parts by weight.
3. facial treatment mask according to claim 1 or 2, it is characterised in that second major ingredient also gathers including oat β-Portugal
Sugared 0.1-0.8 parts by weight.
4. facial treatment mask according to claim 3, it is characterised in that the avenabeta glucosan is 0.3-0.6 parts by weight.
A kind of 5. preparation method of facial treatment mask as described in claim any one of 1-4, it is characterised in that including：
The auxiliary material of mixing is sterilized under conditions of temperature is 115-125 DEG C and pressure is 0.07-0.13MPa,
Then it is cooled to 36-42 DEG C；
First major ingredient is sterilized under conditions of temperature is 115-125 DEG C and pressure is 0.07-0.13MPa, so
After be cooled to 36-42 DEG C；
By the solution filtration sterilization of the epithelical cell growth factor, then with after the auxiliary material after cooling and cooling described in
First major ingredient mixes.
6. the preparation method of facial treatment mask according to claim 5, it is characterised in that the sterilization time of the auxiliary material is
20-40min。
7. the preparation method of facial treatment mask according to claim 5, it is characterised in that the sterilization time of first major ingredient
For 20-40min.
8. the preparation method of facial treatment mask according to claim 5, it is characterised in that the sterilising temp of the auxiliary material is
120-122℃。
9. the preparation method of facial treatment mask according to claim 5, it is characterised in that the sterilising temp of first major ingredient
For 118-121 DEG C.
10. the preparation method of facial treatment mask according to claim 5, it is characterised in that the epithelical cell growth factor
Solution filtration sterilization after mixed with the auxiliary material after cooling and first major ingredient after cooling, then carry out sterile filling.
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| CN201710983834.2A CN107519114A (en) | 2017-10-19 | 2017-10-19 | A kind of facial treatment mask and preparation method thereof |
| PCT/CN2017/109789 WO2019075801A1 (en) | 2017-10-19 | 2017-11-07 | Skincare mask and preparation method therefor |
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| CN201710983834.2A CN107519114A (en) | 2017-10-19 | 2017-10-19 | A kind of facial treatment mask and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108245474A (en) * | 2018-02-11 | 2018-07-06 | 黄扶民 | A kind of facial treatment mask matrix and preparation method |
| CN108403484A (en) * | 2018-06-15 | 2018-08-17 | 广州无添加主义化妆品有限公司 | A kind of fungi polysaccharide fermentation facial mask liquid, facial mask and preparation method |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100752990B1 (en) * | 2006-08-02 | 2007-08-30 | 주식회사 대웅 | Compositions for preventing or treating skin diseases comprising nanoliposomes and natural extracts |
| CN103585097B (en) * | 2013-11-29 | 2015-06-17 | 广州市娇兰化妆品有限公司 | Epidermal growth factor-loaded bletilla rhizome polysaccharide compound, and preparation method and application thereof |
| CN103860449B (en) * | 2014-03-18 | 2016-05-11 | 李健 | A kind of skin care with pregrant abdominal stretch marks-removing effect and preparation method thereof |
| CN104888195A (en) * | 2015-06-19 | 2015-09-09 | 易金阳 | Plant essence peptide composition for promoting wound healing |
| CN105560160B (en) * | 2016-03-16 | 2018-08-17 | 广州市科玮生物技术有限公司 | A kind of facial mask liquid and preparation method thereof containing chitosan |
| CN105726457A (en) * | 2016-03-24 | 2016-07-06 | 烟台市华昕生物医药科技有限公司 | Oligopeptide mask essence |
-
2017
- 2017-10-19 CN CN201710983834.2A patent/CN107519114A/en active Pending
- 2017-11-07 WO PCT/CN2017/109789 patent/WO2019075801A1/en active Application Filing
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108245474A (en) * | 2018-02-11 | 2018-07-06 | 黄扶民 | A kind of facial treatment mask matrix and preparation method |
| CN108403484A (en) * | 2018-06-15 | 2018-08-17 | 广州无添加主义化妆品有限公司 | A kind of fungi polysaccharide fermentation facial mask liquid, facial mask and preparation method |
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| WO2019075801A1 (en) | 2019-04-25 |
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Application publication date: 20171229 |