CN105902461A - Essence containing snail mucus extracts and preparation method thereof - Google Patents

Essence containing snail mucus extracts and preparation method thereof Download PDF

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Publication number
CN105902461A
CN105902461A CN201610311786.8A CN201610311786A CN105902461A CN 105902461 A CN105902461 A CN 105902461A CN 201610311786 A CN201610311786 A CN 201610311786A CN 105902461 A CN105902461 A CN 105902461A
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China
Prior art keywords
essence
skin
percent
formula
glycerol
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Pending
Application number
CN201610311786.8A
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Chinese (zh)
Inventor
蒲源
刘玉平
段红丽
赵萍
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Zhi Yuan Bio Tech Ltd Guangzhou
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Zhi Yuan Bio Tech Ltd Guangzhou
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Priority to CN201610311786.8A priority Critical patent/CN105902461A/en
Publication of CN105902461A publication Critical patent/CN105902461A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

Abstract

The invention relates to essence containing snail mucus extracts. A recipe of the essence comprises the following raw material ingredients in percentage by weight: 1 percent to 4.0 percent of snail slime extracts, 1 percent to 4.0 percent of centella extracts, 2.5 percent to 7 percent of humectants, 1.1 percent to 2.2 percent of thickening agents, 0.01 percent to 0.15 percent of neutralizing agents and the balance de-ionized water. The essence has the advantages that the efficient scar restoration capability can be shown under the condition of low concentration of skin restoration active ingredients in the essence; the wound heeling is accelerated; the skin elasticity improving function and the skin energy improving function are added; the essence can be widely used for the restoration of easy-allergy skin, beatified skin, skin with pimples or injured skin caused by other reasons.

Description

A kind of essence containing Limax pituitary extract and preparation method thereof
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of essence containing Limax pituitary extract and preparation side thereof Method.
Background technology
Along with the continuous deterioration of air quality, during in air, the ozone of excess reduces skin, vitamin C and vitamin E contains Amount so that lipid peroxidation increases;Vehicle exhaust and polycyclic aromatic hydrocarbon, increase oxidative stress and cell injury;In air floating Pollutant, it is easy to enter pore, heavy damage cuticular update cycle and speed;Consumer use in poor quality cosmetic or After cosmetic surgery, there are a series of skin problems such as skin damage, sensitivity, wound infection, skin follow the string in skin.These The performance of skin problem is as follows:
1, after cosmetic surgery, there are the skin problems such as cicatrix, pigmentation, wound infection in skin.
2, cutaneous sensibility increases, and is very easy to occur anaphylaxis, erythema occurs, play red point, the allergic symptom such as itch.
3, skin is lackluster, flexibility decrease, senilism, corse sweat pore, long coarse wool etc..
4, melanin is abnormal calm, and the colour of skin is obscure, and spot colors is deepened, and microgroove increases.
In this case, develop a have reparation cicatrix, accelerate wound healing, increase skin elasticity and improve flesh The product of the height gentleness of skin vigor just becomes the most urgent.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the invention provides a kind of essence containing Limax pituitary extract China's liquid, its formula is contained repairs the active component of skin at very low concentrations, just shows efficient cicatrix reparation, accelerates wound Mouth healing, increase skin elasticity and the function of raising skin vigor, can be widely used for the skin after easy allergy skin, beauty treatment and repair Again, the impaired skin that the skin of long pox or other reason cause.
As follows in order to realize the technical scheme that above-mentioned technical purpose used:
A kind of essence containing Limax pituitary extract, the formula of described essence includes following in percentage by weight Material component: Limax pituitary extract 1%~4.0%;Herba Centellae extract 1%~4.0%;Wetting agent 2.5~7%;Thickening Agent 1.1%~2.2%;Nertralizer 0.01%~0.15%;Deionized water surplus.
Further, the formula of described essence the most also includes following material component to the present invention: anti- Quick dose 1.0~2.5%.
Further, the formula of described essence the most also includes following material component to the present invention: Preservative 0.3%~1.0%.
Preferably, described wetting agent is selected from HANSHENGJIAO, glycerol, pantothenylol and the one or two in base hexyl glycerol Plant above material.
Specifically, described wetting agent is selected from HANSHENGJIAO, glycerol, pantothenylol and base hexyl glycerol, and the most each component is in elite Content in formula of liquid is in percentage by weight: HANSHENGJIAO 0.01%~0.2%;Glycerol 2.0%~6.0%;Pantothenylol 0.1%~0.8%;Base hexyl glycerol 0.05%~0.1%.
Preferred as one, described thickening agent is selected from carbomer and/or butanediol.
Specifically, described thickening agent is carbomer and butanediol, and in essence formula, its content is according to percentage by weight Meter is respectively as follows: carbomer 0.01%~0.15%, butanediol 1.0%~2.0%.
Preferably, described anti-sensitizer is trehalose;Described preservative is caprylyl glycol;Described nertralizer is amino-propanediol.
Another technical purpose of the present invention is to provide the preparation method of the above-mentioned essence containing Limax pituitary extract, including Following steps:
1), each component materials is weighed by formula;
2), by HANSHENGJIAO, carbomer glycerol moistening, it is subsequently adding in aqueous phase pot, opens stirring, be subsequently adding fourth two Alcohol, is warming up to 80 DEG C~90 DEG C, is incubated 10~15 minutes, until being completely dissolved;Its vacuum is sucked in emulsifying pot and stirs Mixing, mixing speed is maintained at 300~350 revs/min, then low speed homogenizing 5~10 minutes;
3), amino-propanediol is added step 2) described in emulsifying pot in, stir evenly, and be cooled to 45~50 DEG C;
4), Limax pituitary extract, Herba Centellae extract are sequentially added into step 3) in gained emulsifying pot, stir evenly;Stirring When being cooled to less than 40 DEG C, adding base hexyl glycerol, caprylyl glycol, homogenizing also stirs evenly;It is down to discharging when 30~35 DEG C.
Beneficial effects of the present invention:
Compared with prior art, the essence containing Limax pituitary extract of the present invention has the advantages that
1, inventive formulation with the addition of natural origin, uses that smudge cells technology separates, rich in asiatic acid and hydroxyl Base asiatic acid, asiaticoside and the Herba Centellae extract of asiaticoside isoreactivity composition, can participate in normal wound In repair process, mainly protect the healing into wound by increase I-type collagen, the inflammation produced by inflammatory mediator can be suppressed The factor.Herba Centellae extract has outstanding healing of wound and cicatrix repair, and its reason is that asiaticoside has promotion body Interior collage synthesis and new vascular generation, stimulate the important function such as granulation growth, so beneficially wound healing.As at skin wound The upper continuous administration preparation containing asiaticoside, can prevent wound infection from suppurating, and shortens wound healing time, it is possible to decrease skin hardness With improve skin-nourishing, the effect of enhancing metabolism.
2, in product Limax pituitary extract contain collagen protein, elastin, chondroitin sulfate, allantoin, glycolic, Natural antibacterial peptide, vitamin, calcium, ferrum, copper, phosphorus, etc. the nutrient substance wanted of multiple needed by human body.Use cryogenic high pressure difference Multistage Membranes Isolation technics, have Glycerin, repair skin injury, promote wound healing, stimulate cell regeneration, horny layer softening albumin layer, Help the skin efficacy effect to aspects such as free radical resistings, may be used for prevention and improve cicatrix.
3, the present invention uses two kinds of active component with obvious skin repair effect, and Herba Centellae extract is plant origin , another kind is animal origin, and the different types of active skull cap components of both is organically combined, and can produce between them Raw synergistic function.Asiaticoside in described Herba Centellae extract can effectively facilitate skin in Limax pituitary extract The absorption of collagen component, thus be greatly improved collagen protein effect to skin repair.
4, the essence containing Limax pituitary extract of the present invention can keep skin young, fine and smooth, makes skin tight and rich Flexible.
5, the essence containing Limax pituitary extract of the present invention can micro-stripping skin, enhance metabolism, prevent skin The appearance of problem;Glycolic, also known as hydroxyacetic acid, glycolic acid, is simplest 'alpha '-hydroxy acids.It can be easy to penetrate into skin Inside skin, solve the problems such as skin aging, wrinkle, black speck, skin sore at short notice.
6, the product of the present invention does not contains emulsifying agent and surfactant, is the suspension thick stabilization system of a kind of uniqueness, it Without dioxane, without mineral origin composition, without pigment, without essence, the safety of formula system is high, can be generally applicable In all kinds of skin quality and various people.
Detailed description of the invention
In order to make the object, technical solutions and advantages of the present invention definitely, below the preferred embodiments of the present invention are entered The description that row is detailed.The content of each component in following embodiment calculates with percentage by weight, and unit of weight can be thousand Gram or kilogram." the Limax pituitary extract L " that the Limax pituitary extract of the present invention produces purchased from Guangzhou network victory.The present invention's is long-pending Snow grass extract is purchased from BIOSPECTRUM company of Korea S, its trade name HerbEx Centella ExtractTM
One, the formula of the essence containing Limax pituitary extract
Table 1 embodiment 1~5 essence and the formula of reference examples 1
Two, the preparation method of the essence containing Limax pituitary extract
The essence preparation method containing Limax pituitary extract of the present invention, its step is as follows:
1). each component raw material of formula is weighed according to table 1.
2). by the HANSHENGJIAO in component A, carbomer glycerol moistening, it is subsequently adding in aqueous phase pot, opens stirring, successively Add other remaining component A, be warming up to 80 DEG C, be incubated 10 minutes, until being completely dissolved.The mixing speed of emulsifying pot is maintained at 300 revs/min, component A is sucked by vacuum, low speed (speed is) homogenizing 5 minutes.
3). the raw material of B component is added in emulsifying pot, open stirring, mix and be cooled to 45 DEG C.
4). component C is sequentially added in emulsifying pot, stirs evenly;Stirring cooling 35~40 DEG C, adds D component, and homogenizing also stirs Even;Being down to discharging when 35 DEG C, it is qualified to check, discharging fill.
Comparative example 1 uses the identical preparation method of embodiment 1~5.
Three, measure of merit
1. cicatrix repairs efficacy assessments
Cicatrix reparation evaluation methodology:
1) study subject: embodiment 1~5.
2) negative control: commercially available famous brand name scar rehabilitating solution.
3) experimenter: 240 cicatrixes repair patient, age 18~40 years old, these cicatrixes reparation patient patient are divided at random Becoming two groups, four groups of experimenter's qualifications and record of service are basically identical, without significant difference, have a comparability:
A, treatment group 40 example, wherein male 22 example, women 18 example, mild scar 15 example, moderate 12 example, severe 13 example, scar Average 6.5 years of age;
B, treatment group 40 example, wherein male 21 example, women 19 example, mild scar 14 example, moderate 13 example, severe 13 example, scar Average 6.3 years of age;
C, treatment group 40 example, wherein male 20 example, women 20 example, mild scar 16 example, moderate 11 example, severe 13 example, scar Average 6.7 years of age;
D, treatment group 40 example, wherein male 22 example, women 18 example, mild scar 15 example, moderate 11 example, severe 14 example, scar Average 6.7 years of age;
E, treatment group 40 example, wherein male 19 example, women 21 example, mild scar 16 example, moderate 11 example, severe 13 example, scar Average 6.6 years of age;
F, matched group 40 example, wherein male 23 example, women 17 example, mild scar 16 example, moderate 12 example, severe 12 example, scar Average 6.6 years of age;
4) product is used
A, treatment group patient use the essence (embodiment 1~5) of the present invention, at clear water cleaning cicatrix, dry, incite somebody to action this Invention essence uniform application is in affected part, and with referring to that abdomen is massaged into essence gently and fully absorbs, every day uses once, uses continuously Three months.
B, matched group patient use commercially available famous brand name scar rehabilitating solution, at clear water cleaning cicatrix, dry, by this Bright essence uniform application is in affected part, with referring to that abdomen is massaged into ointment gently and fully absorbs medication every day once, and medication three months.
5) efficacy determination:
Effective: after medication one month, cicatrix is the most thin out, medication three months, cicatrix is repaired completely;
Effective: after medication one month, cicatrix is the most thin out, is continuing with, and cicatrix take a favorable turn and is not but wholly absent;
Invalid: after medication one month, cicatrix is without significant change.
6), experimental result is as shown in table 2:
Table 2 cicatrix repairing effect test result
Conclusion: clinical treatment outcome shows, the therapeutic effect of embodiment 3~5, total effective rate will apparently higher than reference examples 1, Also apparently higher than the embodiment 1~2 of use single component (containing only Limax pituitary extract L or only containing Herba Centellae extract), It can be seen that the effect repairing cicatrix of the essence of the art of this patent is far superior to commercially available famous brand name cicatrix reparation Liquid.
2, Product Safety assessment
Product safety evaluation methodology:
1), study subject: embodiment 1~5
2), negative control: reference examples 1
3), experimenter: totally 30 people, age 18~40 years old, sensitivity skin crowd.
4), speckle method for testing: select qualified speckle examination device, with closed patch test method, by tested material about 0.02ml~ 0.025ml is applied in speckle examination device, and external special adhesive tape is pasted on experimenter's forearm song side, removes tested material, in going after 24 hours Except 30min after tested material speckle examination device, after impression disappears, observe dermoreaction, by " cosmetics health specification " (version in 2007) Dermoreaction grade scale records its result.
5), evaluation of result:
Table 3 skin adverse reaction grade scale
6), result of the test:
Table 4 cosmetics human skin patch result
Human skin patch result shows:
1), in embodiment 3~5,30 subjects skin's the most negative (grading system: 0 grade).According to " changing Cosmetic hygienic practice " (version in 2007) human body skin class patch test criterion, sample to human body without skin adverse reaction.
A, embodiment 3~5 are compared with embodiment 1~2, reference examples 1, and embodiment 3~5 shows higher safety, i.e. Make using the crowd at sensitive skin, any abnormal response does not the most occur;
B and individually contain sample i.e. embodiment 1 or the embodiment 2 of Herba Centellae extract or Limax pituitary extract, all Occur in that the untoward reaction of a few example;
C, embodiment 1 are compared with reference examples 1, and embodiment 1 shows higher safety and mildness.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right The restriction of embodiments of the present invention.For those of ordinary skill in the field, the most also may be used To make other changes in different forms.Here cannot all of embodiment be given exhaustive.Every belong to this What bright technical scheme was extended out obviously changes or changes the row still in protection scope of the present invention.

Claims (9)

1. the essence containing Limax pituitary extract, it is characterised in that the formula of described essence is according to percentage by weight Count and include following material component: Limax pituitary extract 1%~4.0%;Herba Centellae extract 1%~4.0%;Wetting agent 2.5 ~7%;Thickening agent 1.1%~2.2%;Nertralizer 0.01%~0.15%;Deionized water surplus.
Essence the most according to claim 1, it is characterised in that the formula of described essence the most also wraps Include following material component: anti-sensitizer 1.0~2.5%.
Essence the most according to claim 1, it is characterised in that the formula of described essence the most also wraps Include following material component: preservative 0.3%~1.0%.
4. according to essence described in any one in claims 1 to 3, it is characterised in that described wetting agent is selected from HANSHENGJIAO, sweet Oil, pantothenylol and one or more the material in base hexyl glycerol.
Essence the most according to claim 4, it is characterised in that described wetting agent is selected from HANSHENGJIAO, glycerol, pantothenylol and base Hexyl glycerol, the most each component content in essence formula is in percentage by weight: HANSHENGJIAO 0.01%~ 0.2%;Glycerol 2.0%~6.0%;Pantothenylol 0.1%~0.8%;Base hexyl glycerol 0.05%~0.1%.
6. according to essence described in any one in claim 5, it is characterised in that described thickening agent selected from carbomer and/or Butanediol.
7. according to essence described in any one in claim 6, it is characterised in that described thickening agent is carbomer and fourth two Alcohol, in essence formula, its content is respectively as follows: carbomer 0.01%~0.15%, butanediol in percentage by weight 1.0%~2.0%.
8. according to essence described in any one in claim 7, it is characterised in that described anti-sensitizer is trehalose;Described anti- Rotten agent is caprylyl glycol;Described nertralizer is amino-propanediol.
9. the preparation method preparing the essence containing Limax pituitary extract as claimed in claim 8, it is characterised in that Comprise the following steps:
1), each component materials is weighed by formula;
2), by HANSHENGJIAO, carbomer glycerol moistening, it is subsequently adding in aqueous phase pot, opens stirring, be subsequently adding butanediol, rise Temperature, to 80 DEG C~90 DEG C, is incubated 10~15 minutes, until being completely dissolved;Its vacuum sucked in emulsifying pot and is stirred, stirring Mix speed and be maintained at 300~350 revs/min, then low speed homogenizing 5~10 minutes;
3), amino-propanediol is added step 2) described in emulsifying pot in, stir evenly, and be cooled to 45~50 DEG C;
4), Limax pituitary extract, Herba Centellae extract are sequentially added into step 3) in gained emulsifying pot, stir evenly;Stirring cooling During to less than 40 DEG C, adding base hexyl glycerol, caprylyl glycol, homogenizing also stirs evenly;It is down to discharging when 30~35 DEG C.
CN201610311786.8A 2016-05-11 2016-05-11 Essence containing snail mucus extracts and preparation method thereof Pending CN105902461A (en)

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Cited By (14)

* Cited by examiner, † Cited by third party
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CN106333917A (en) * 2016-10-09 2017-01-18 上海兰葹生物科技有限公司 Dendrobium nobile skin regeneration promotion combination essence
CN106389293A (en) * 2016-11-26 2017-02-15 上海兰葹生物科技有限公司 Dendrobium huoshanense-containing combined essence capable of promoting skin regeneration
CN106620652A (en) * 2016-09-28 2017-05-10 潘卫方 Nano-ion antibacterial tissue regeneration promoting care solution and preparation method thereof
CN107028841A (en) * 2017-05-25 2017-08-11 杭州千岛湖蓝色天使实业有限公司 A kind of anti-fog haze Essence
CN107213041A (en) * 2017-06-20 2017-09-29 芜湖凌梦电子商务有限公司 A kind of preparation method of gloiopeltis algae Essence
CN107375906A (en) * 2017-07-28 2017-11-24 广东科玮生物技术股份有限公司 A kind of scar repair agent and preparation method thereof
CN108175727A (en) * 2017-12-28 2018-06-19 广州蜜妆生物科技有限公司 A kind of anti-acne print Face-protecting mask patch and preparation method thereof
CN109646388A (en) * 2019-03-04 2019-04-19 广州市华晟健康产业有限公司 One kind having the effect of intensive maintenance property Medical-use cold compress pad pasting
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CN112438903A (en) * 2019-08-28 2021-03-05 科丝美诗株式会社 Cosmetic composition for skin irritation reduction and skin inflammation reduction comprising sorbitol or a mixture thereof as an active ingredient
CN113509545A (en) * 2021-06-23 2021-10-19 哈尔滨运美达生物科技有限公司 Medical recombinant collagen repair patch and essence of medical recombinant collagen repair patch and preparation methods of medical recombinant collagen repair patch and essence
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793655A (en) * 2012-08-10 2012-11-28 彭再辉 Regenerating and repairing mask liquid by applying snail mucus extract and preparation method thereof
CN104207977A (en) * 2014-08-21 2014-12-17 广州市美立方化妆品有限公司 Bioactive peptide anti-aging wrinkle-removing sensitivity-relieving essence and preparation method thereof
CN104248548A (en) * 2013-06-26 2014-12-31 青岛道合生物科技有限公司 Plant extract-containing oxidation-resistant essence
CN104983656A (en) * 2015-06-19 2015-10-21 广州科玛生物科技有限公司 CC cream and preparation method thereof
CN105012208A (en) * 2014-10-27 2015-11-04 陈俊杰 Essence liquid capable of activating skin vitality and restraining aging
CN105250187A (en) * 2015-11-18 2016-01-20 中山市艾丽意素生物科技有限公司 Plant active peptide firming facial mask essence and application thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793655A (en) * 2012-08-10 2012-11-28 彭再辉 Regenerating and repairing mask liquid by applying snail mucus extract and preparation method thereof
CN104248548A (en) * 2013-06-26 2014-12-31 青岛道合生物科技有限公司 Plant extract-containing oxidation-resistant essence
CN104207977A (en) * 2014-08-21 2014-12-17 广州市美立方化妆品有限公司 Bioactive peptide anti-aging wrinkle-removing sensitivity-relieving essence and preparation method thereof
CN105012208A (en) * 2014-10-27 2015-11-04 陈俊杰 Essence liquid capable of activating skin vitality and restraining aging
CN104983656A (en) * 2015-06-19 2015-10-21 广州科玛生物科技有限公司 CC cream and preparation method thereof
CN105250187A (en) * 2015-11-18 2016-01-20 中山市艾丽意素生物科技有限公司 Plant active peptide firming facial mask essence and application thereof

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620652A (en) * 2016-09-28 2017-05-10 潘卫方 Nano-ion antibacterial tissue regeneration promoting care solution and preparation method thereof
CN106333917A (en) * 2016-10-09 2017-01-18 上海兰葹生物科技有限公司 Dendrobium nobile skin regeneration promotion combination essence
CN106389293A (en) * 2016-11-26 2017-02-15 上海兰葹生物科技有限公司 Dendrobium huoshanense-containing combined essence capable of promoting skin regeneration
CN107028841A (en) * 2017-05-25 2017-08-11 杭州千岛湖蓝色天使实业有限公司 A kind of anti-fog haze Essence
CN107213041A (en) * 2017-06-20 2017-09-29 芜湖凌梦电子商务有限公司 A kind of preparation method of gloiopeltis algae Essence
CN107375906B (en) * 2017-07-28 2018-06-08 广东科玮生物技术股份有限公司 A kind of scar repair agent and preparation method thereof
CN107375906A (en) * 2017-07-28 2017-11-24 广东科玮生物技术股份有限公司 A kind of scar repair agent and preparation method thereof
CN108175727A (en) * 2017-12-28 2018-06-19 广州蜜妆生物科技有限公司 A kind of anti-acne print Face-protecting mask patch and preparation method thereof
CN109646388A (en) * 2019-03-04 2019-04-19 广州市华晟健康产业有限公司 One kind having the effect of intensive maintenance property Medical-use cold compress pad pasting
CN109846739A (en) * 2019-03-18 2019-06-07 惠州市旭东实业有限公司 A kind of moisturizing facial soap
CN112245382A (en) * 2019-07-03 2021-01-22 广东巴松那生物科技有限公司 Skin-smoothing scrub essence and preparation method thereof
CN112438903A (en) * 2019-08-28 2021-03-05 科丝美诗株式会社 Cosmetic composition for skin irritation reduction and skin inflammation reduction comprising sorbitol or a mixture thereof as an active ingredient
CN110613650A (en) * 2019-10-25 2019-12-27 上海伽誉生物科技有限公司 Essence containing okra hydrolyzed glycoprotein SILKY-WSP and preparation method thereof
CN113509545A (en) * 2021-06-23 2021-10-19 哈尔滨运美达生物科技有限公司 Medical recombinant collagen repair patch and essence of medical recombinant collagen repair patch and preparation methods of medical recombinant collagen repair patch and essence
CN114028314A (en) * 2021-11-23 2022-02-11 广东画景医药生物科技有限公司 Centella asiatica snail nourishing and refreshing mask and preparation method thereof

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