CN109477063A - 具有改变的醛：铁氧还蛋白氧化还原酶活性的微生物和相关方法 - Google Patents

具有改变的醛：铁氧还蛋白氧化还原酶活性的微生物和相关方法 Download PDF

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Publication number
CN109477063A
CN109477063A CN201780029930.1A CN201780029930A CN109477063A CN 109477063 A CN109477063 A CN 109477063A CN 201780029930 A CN201780029930 A CN 201780029930A CN 109477063 A CN109477063 A CN 109477063A
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clostridium
bacterium
naturally occurring
enzyme
bacterial strain
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Chinese (zh)
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F·刘
M·科普克
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Langze Technology Co Ltd
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Langze Technology Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/07—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with an iron-sulfur protein as acceptor (1.2.7)
    • C12Y102/07005—Aldehyde ferredoxin oxidoreductase (1.2.7.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
CN201780029930.1A 2016-05-14 2017-05-12 具有改变的醛：铁氧还蛋白氧化还原酶活性的微生物和相关方法 Pending CN109477063A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662336639P 2016-05-14 2016-05-14
US62/336,639 2016-05-14
PCT/US2017/032564 WO2017200884A1 (en) 2016-05-14 2017-05-12 Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods

Publications (1)

Publication Number Publication Date
CN109477063A true CN109477063A (zh) 2019-03-15

Family

ID=60295016

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CN201780029930.1A Pending CN109477063A (zh) 2016-05-14 2017-05-12 具有改变的醛：铁氧还蛋白氧化还原酶活性的微生物和相关方法

Country Status (10)

Country Link
US (1) US10294498B2 (https=)
EP (1) EP3464559A4 (https=)
JP (2) JP7502029B2 (https=)
KR (2) KR102514023B1 (https=)
CN (1) CN109477063A (https=)
CA (1) CA3024114C (https=)
EA (1) EA201892627A1 (https=)
SG (1) SG11201810031RA (https=)
WO (1) WO2017200884A1 (https=)
ZA (1) ZA201807617B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017200884A1 (en) * 2016-05-14 2017-11-23 Lanzatech, Inc. Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
KR102073308B1 (ko) * 2017-08-29 2020-02-05 광주과학기술원 에탄올 비생산성 아세토젠 균주를 에탄올 생성균주로 전환하는 방법 및 상기 에탄올 생성균주로부터 일산화탄소를 이용한 에탄올의 제조방법
CN109929862B (zh) * 2019-03-14 2022-09-16 云南农业大学 一种从反刍动物瘤胃宏转录组数据筛选纤维素酶基因进行克隆的方法

Citations (4)

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US20100151543A1 (en) * 2008-12-16 2010-06-17 Andrew Reeves Recombinant microorganisms having modified production of alcohols and acids
CN103582703A (zh) * 2011-03-31 2014-02-12 新西兰郎泽科技公司 一种用于控制丁二醇生产的发酵方法
US20150079650A1 (en) * 2013-06-05 2015-03-19 Lanzatech New Zealand Limited Recombinant microorganisms exhibiting increased flux through a fermentation pathway
CN105051178A (zh) * 2013-03-15 2015-11-11 朗泽科技新西兰有限公司 用于在微生物发酵中控制代谢物产生的系统和方法

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UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
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JP5600296B2 (ja) 2007-11-13 2014-10-01 ランザテク・ニュージーランド・リミテッド 新規細菌及びその使用法
CN102317463B (zh) 2008-06-09 2014-12-03 蓝瑟科技纽西兰有限公司 厌氧微生物发酵生产丁二醇
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Also Published As

Publication number Publication date
JP7502029B2 (ja) 2024-06-18
JP2022163046A (ja) 2022-10-25
KR20230044031A (ko) 2023-03-31
JP2019514441A (ja) 2019-06-06
WO2017200884A1 (en) 2017-11-23
CA3024114C (en) 2020-02-04
CA3024114A1 (en) 2017-11-23
EP3464559A1 (en) 2019-04-10
US20170327849A1 (en) 2017-11-16
US10294498B2 (en) 2019-05-21
SG11201810031RA (en) 2018-12-28
KR102514023B1 (ko) 2023-03-23
KR20190017790A (ko) 2019-02-20
EA201892627A1 (ru) 2019-04-30
ZA201807617B (en) 2021-04-28
EP3464559A4 (en) 2020-02-12

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