CN109476663B - 用于治疗癌症的吡唑并吡啶衍生物 - Google Patents

用于治疗癌症的吡唑并吡啶衍生物 Download PDF

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Publication number
CN109476663B
CN109476663B CN201780045658.6A CN201780045658A CN109476663B CN 109476663 B CN109476663 B CN 109476663B CN 201780045658 A CN201780045658 A CN 201780045658A CN 109476663 B CN109476663 B CN 109476663B
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compound
cancer
inhibitors
carcinoma
mixture
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CN109476663A (zh
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P·西尔
S·布朗纳
F·A·罗梅罗
S·马格努森
V·H-W·徐
J·M·默里
J·瓦伊
K·W·赖
F·王
K·X·陈
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Genentech Inc
Constellation Pharmaceuticals Inc
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Genentech Inc
Constellation Pharmaceuticals Inc
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Health & Medical Sciences (AREA)
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  • Diabetes (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
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CN201780045658.6A 2016-05-24 2017-05-24 用于治疗癌症的吡唑并吡啶衍生物 Active CN109476663B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2016/083118 2016-05-24
CN2016083118 2016-05-24
PCT/US2017/034326 WO2017205538A1 (en) 2016-05-24 2017-05-24 Pyrazolopyridine derivatives for the treatment of cancer

Publications (2)

Publication Number Publication Date
CN109476663A CN109476663A (zh) 2019-03-15
CN109476663B true CN109476663B (zh) 2021-11-09

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US (2) US11247989B2 (https=)
EP (1) EP3464286B1 (https=)
JP (1) JP7014736B2 (https=)
CN (1) CN109476663B (https=)
MA (1) MA45146A (https=)
WO (1) WO2017205538A1 (https=)

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JP7777131B2 (ja) 2020-10-02 2025-11-27 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム 転写活性化タンパク質のイミダゾピペラジン阻害剤
WO2022093817A1 (en) * 2020-10-26 2022-05-05 Yale University Macrophage migration inhibitory factor inhibitors, and methods of making and using same
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US20240122941A1 (en) * 2020-12-25 2024-04-18 National Cancer Center Therapy based on synthetic lethality in swi/snf complex-dysfunction cancer
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