CN109444028A - A kind of particle analyzer and its liquid channel system, discharging of waste liquid method - Google Patents
A kind of particle analyzer and its liquid channel system, discharging of waste liquid method Download PDFInfo
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- CN109444028A CN109444028A CN201811605399.0A CN201811605399A CN109444028A CN 109444028 A CN109444028 A CN 109444028A CN 201811605399 A CN201811605399 A CN 201811605399A CN 109444028 A CN109444028 A CN 109444028A
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- 239000007788 liquid Substances 0.000 title claims abstract description 142
- 239000002699 waste material Substances 0.000 title claims abstract description 91
- 239000002245 particle Substances 0.000 title claims abstract description 42
- 238000007599 discharging Methods 0.000 title claims abstract description 9
- 238000000034 method Methods 0.000 title claims abstract description 9
- 239000012530 fluid Substances 0.000 claims abstract description 105
- 238000004140 cleaning Methods 0.000 claims abstract description 82
- 238000005070 sampling Methods 0.000 claims abstract description 31
- 238000010408 sweeping Methods 0.000 claims abstract description 3
- 238000012546 transfer Methods 0.000 claims description 20
- 238000010926 purge Methods 0.000 claims description 11
- 238000001514 detection method Methods 0.000 abstract description 14
- 238000012360 testing method Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 230000007547 defect Effects 0.000 description 4
- 238000012423 maintenance Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
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- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of particle analyzer and its liquid channel systems, discharging of waste liquid method.The liquid channel system of particle analyzer includes: sheath fluid supplying module, for supplying sheath fluid；Waste liquid receiving module, for receiving waste liquid；Sample-feed module, including sampling needle, for acquiring and supplying sample；Flow chamber, for sweeping along sample to flow through for sheath fluid, the flow chamber has sample entrance port, sheath fluid entrance and waste liquid outlet, and the sample entrance port is connected to sampling needle, the sheath fluid entrance is connected to sheath fluid supplying module, and the waste liquid outlet is connected to waste liquid receiving module by the first sewer pipe；Cleaning module, the cleaning module are connected to sheath fluid supplying module by the first cleaning pipe and are cleaned with the outer wall to sampling needle, and the cleaning module is connected to waste liquid receiving module by the second sewer pipe the waste liquid of cleaning module is expelled to waste liquid receiving module.Stability using the signal detection of the particle analyzer of the liquid channel system is high.
Description
Technical field
The present invention relates to cell analysis detection device technical field more particularly to a kind of particle analyzer and its fluid path systems
System, discharging of waste liquid method, the particle analyzer especially cytoanalyze.
Background technique
Flow cytometer is the device that cell or biological particle are automatically analyzed and sorted, can quickly detect,
Characteristic parameter in terms of storage, a series of important biophysics for showing the cell dispersion to float on a liquid, biochemistry,
And specified cell subsets can be sorted out according to the parameter ranges of pre-selection, it is widely used to cell biology, is immunized
The basic research such as, physiology, molecular biology, while being also used for the clinical diagnosis of medicine, environment measuring etc..Its
In, liquid channel system is one of core system of flow cytometer, and by liquid channel system, sheath fluid is wrapped in sample week to be detected
It encloses, can guarantee that cell or biological particle are lined up the flow chamber by flow cytometer, therefore, flow chamber mesotheca liquid stream is dynamic to put down
Stability has great influence for the stability of signal detection.The discharging of waste liquid of existing flow cytometer is easy in flow chamber
Sheath stream causes to disturb, and then influences the stability of signal detection.
Summary of the invention
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide a kind of fluid path systems of particle analyzer
System, the particle analyzer especially cytoanalyze, the liquid channel system can be effectively prevent and be eliminated in cleaning waste-solution line
The disturbance of sheath stream, improves the stability of signal detection when positive pressure normal to instrument loading.
The second object of the present invention is to provide a kind of particle analyzer using above-mentioned liquid channel system, the particle analyzer
Especially cytoanalyze.
The third object of the present invention is to provide a kind of discharging of waste liquid method of particle analyzer.
The purpose of the present invention is implemented with the following technical solutions:
A kind of liquid channel system of particle analyzer, comprising:
Sheath fluid supplying module, for supplying sheath fluid；
Waste liquid receiving module, for receiving waste liquid；
Sample-feed module, including sampling needle, for acquiring and supplying sample；
Flow chamber, for sweeping along sample to flow through for sheath fluid, the flow chamber has sample entrance port, sheath fluid entrance and waste liquid
Outlet, the sample entrance port are connected to sampling needle, and the sheath fluid entrance is connected to sheath fluid supplying module, and the waste liquid outlet passes through first
Sewer pipe is connected to waste liquid receiving module；
Cleaning module, the cleaning module by the first cleaning pipe be connected to sheath fluid supplying module with the outer wall to sampling needle into
Row cleaning, the cleaning module are connected to waste liquid receiving module by the second sewer pipe the waste liquid of cleaning module is expelled to waste liquid
Receiving module.
Preferably, the sheath fluid entrance is connected to sheath fluid supplying module by the first branch pipe, along sheath fluid on first branch pipe
Flow direction is disposed with sheath liquid filter, check valve and sheath fluid buffer.
Preferably, the first transfer tube and first switch valve, first transfer tube position are additionally provided on first branch pipe
On the first branch pipe between sheath liquid filter and sheath fluid supplying module, the first switch valve is located at sheath fluid buffer and sheath fluid
On first branch pipe of entrance.
Preferably, the sample entrance port is connected to sampling needle by the second branch pipe, is provided with the second drive on second branch pipe
Dynamic pump.
Preferably, the flow chamber also has cleaning entrance, and the cleaning entrance is connected to sheath fluid by the second cleaning pipe and supplies
It is connected to sampling needle to module, by the second branch pipe, is provided with the second purge valve in second cleaning pipe.
Preferably, pass through third cleaning pipe is connected to sheath fluid supplying module to first cleaning pipe simultaneously with the second cleaning pipe,
It is provided with the first purge valve in first cleaning pipe, is provided with the 4th transfer tube in the third cleaning pipe.
Preferably, it is provided with second switch valve on first sewer pipe, third drive is provided on second sewer pipe
Dynamic pump.
Preferably, the cleaning module includes service sink, and service sink is accessed on the top in the first cleaning pipe self-cleaning pond,
Service sink is accessed in the lower part in the second sewer pipe self-cleaning pond.
A kind of particle analyzer, the particle analyzer include the liquid channel system of above-mentioned particle analyzer.
A kind of discharging of waste liquid method of particle analyzer, the particle analyzer include waste liquid receiving module, flow chamber and
Cleaning module, the flow chamber have sample entrance port, sheath fluid entrance and waste liquid outlet, and the waste liquid outlet passes through the first sewer pipe
It is connected to waste liquid receiving module, the waste liquid of flow chamber is individually expelled to by waste liquid receiving module by the first sewer pipe, it is described clear
Mold cleaning block is connected to waste liquid receiving module by the second sewer pipe, and the waste liquid of cleaning module is individually discharged by the second sewer pipe
To waste liquid receiving module.
Compared with prior art, beneficial effects of the present invention include at least:
By by liquid channel system the first sewer pipe and the second sewer pipe be arranged to two individual pipelines, the second waste liquid
Remaining positive pressure will not be conducted to the first sewer pipe and flow chamber in pipe, will not generate disturbance to the sheath stream of flow chamber, can be with
Prevent the positive pressure in the second sewer pipe from impacting to the sheath hydraulic coupling in flow chamber, the first sewer pipe of flow chamber is using closing
Circuit ensure that sheath fluid stability, and the stability of the signal detection of particle analyzer is high, improve the CV value of detection signal, and
Reduce the waiting time cleaned between test tube, improves the detection efficiency of instrument, meanwhile, it does not dissipate completely also in the second sewer pipe
Positive pressure will not by waste liquid be pressed into flow chamber in, thus avoid flowing chamber contamination.
Detailed description of the invention
Fig. 1 is the schematic diagram for the liquid channel system that the sheath stream of flow chamber can generate the particle analyzer of disturbance.
Fig. 2 is the schematic diagram of the liquid channel system of the particle analyzer of the embodiment of the present invention.
In figure: 10a, sheath fluid bucket；11a, sheath liquid filter；12a, sheath fluid buffer；20a, waste liquid barrel；21a, sewer pipe
Road；30a, sampling needle；40a, flow chamber；41a, waist valve；50a, service sink；10, sheath fluid supplying module；11, sheath liquid filter；
12, sheath fluid buffer；13, check valve；20, waste liquid receiving module；21, the first sewer pipe；22, the second sewer pipe；30, it samples
Needle；40, flow chamber；41, sample entrance port；42, sheath fluid entrance；43, waste liquid outlet；44, entrance is cleaned；50, service sink；61,
One branch pipe；62, the second branch pipe；71, first switch valve；72, second switch valve；73, the first purge valve；74, the second purge valve；
81, the first cleaning pipe；82, the second cleaning pipe；P1, the first transfer tube；P2, the second transfer tube；P3, third transfer tube；P4, the 4th
Transfer tube.
Specific embodiment
Example embodiment is described more fully with reference to the drawings.However, example embodiment can be with a variety of shapes
Formula is implemented, and is not understood as limited to embodiment set forth herein；On the contrary, thesing embodiments are provided so that the present invention more
Fully and completely, and by the design of example embodiment comprehensively it is communicated to those skilled in the art.
The word of expression position and direction described in the present invention, is the explanation carried out by taking attached drawing as an example, but according to need
It can also make a change, done change is all contained in the scope of the present invention.Arrow indicates the flow direction of liquid in figure.
Fig. 1 is the schematic diagram for the liquid channel system that the sheath stream of flow chamber 40a can generate the particle analyzer of disturbance, shown in Fig. 1
Liquid channel system include sheath fluid bucket 10a, waste liquid barrel 20a, sampling needle 30a, flow chamber 40a and service sink 50a.Liquid shown in FIG. 1
First defect existing for the system of road is that the waste-solution line 21a of connection waste liquid barrel 20a only has one, and waste-solution line 21a is simultaneously
It is connected to the waste liquid outlet of flow chamber 40a and the waste liquid outlet of service sink 50a, when moving back sample cleaning between test tube, waste drains pump will be cleaned
Waste liquid barrel 20a is extracted from service sink 50a and be discharged into the waste liquid of sampling needle 30a out, flow when being worked normally due to the waste drains pump
It is larger, biggish positive pressure can be generated in waste-solution line 21a and is able to maintain a period of time.When the normal loading of particle analyzer
When, the positive pressure not dissipated completely also in waste-solution line 21a can generate disturbance, the sheath stream of the disturbance to the sheath stream in flow chamber 40a
The stability of the signal detection of particle analyzer can be impacted, meanwhile, the positive pressure not dissipated completely also in waste-solution line 21a
In the presence of waste liquid to be pressed into the risk of flow chamber 40a, so that flow chamber 40a be caused to pollute.
For above-mentioned first defect, referring to Fig. 2, the present invention provides a kind of particle analyzer, the liquid of the particle analyzer
Road system includes sheath fluid supplying module 10, waste liquid receiving module 20, sample-feed module, flow chamber 40 and cleaning module, the liquid
Road system can effectively prevent the disturbance of sheath stream when positive pressure normal to the instrument loading in cleaning waste-solution line, improve signal detection
Stability, while can prevent the positive pressure not dissipated completely also in sewer pipe by waste liquid be pressed into flow chamber 40, prevent flow chamber
40 is contaminated.
Specifically, sheath fluid supplying module 10 includes sheath fluid bucket or sheath liquid pool for supplying sheath fluid, sheath fluid supplying module 10.
Waste liquid receiving module 20 includes waste liquid barrel or waste liquid pool for receiving waste liquid, waste liquid receiving module 20.Sample-feed module is used for
Acquisition and supply sample, sample-feed module include sampling needle 30, and sampling needle 30 can acquire sample from the test tube equipped with sample
This.
Flow chamber 40 is used to sweep along sample to flow through for sheath fluid, and flow chamber 40 has sample entrance port 41,42 and of sheath fluid entrance
Waste liquid outlet 43.Wherein, sample entrance port 41 is connected to sampling needle 30, and the sample that sampling needle 30 acquires enters from sample entrance port 41 to be flowed
Room 40, sheath fluid entrance 42 are connected to sheath fluid supplying module 10, and the sheath fluid of sheath fluid supplying module 10 enters flow chamber from sheath fluid entrance 42
40 and sample is swept along to be lined up through flow chamber 40, waste liquid outlet 43 is connected to waste liquid receiving module 20 by the first sewer pipe 21,
Sample and sheath fluid after detection are expelled to waste liquid receiving module 20 through the first sewer pipe 21 from waste liquid outlet 43 as waste liquid.
Cleaning module is connected to sheath fluid supplying module 10 by the first cleaning pipe 81, and cleaning module includes service sink 50, one
After secondary sampling, the sheath fluid supplied by sheath fluid supplying module 10 through the first cleaning pipe 81 carries out the outer wall of sampling needle 30 clear
It washes, prevents the remaining sample of the outer wall of sampling needle 30 from polluting to next sample to be collected, in the present embodiment, first is clear
Wash the top access service sink 50 in 81 self-cleaning pond 50 of pipe.Cleaning module is connected to waste liquid receiving module by the second sewer pipe 22
20, the waste liquid for cleaning sampling needle 30 is expelled to waste liquid receiving module 20 through the second sewer pipe 22, in the present embodiment, the second sewer pipe
Service sink 50 is accessed in the lower part in 22 self-cleaning ponds 50.
First sewer pipe 21 of second sewer pipe 22 and the waste liquid for exhaust flow room 40 is two individual pipelines,
The waste liquid of flow chamber 40 is individually expelled to waste liquid receiving module 20 by the first sewer pipe 21, it will by the second sewer pipe 22
The advantages of waste liquid of cleaning module is individually expelled to waste liquid receiving module 20, the structure setting and discharging of waste liquid method be,
Remaining positive pressure will not be conducted to the first sewer pipe 21 and flow chamber 40 in second sewer pipe 22, will not be to the sheath of flow chamber 40
The raw disturbance of miscarriage, accordingly it is possible to prevent the positive pressure in the second sewer pipe 22 impacts the sheath hydraulic coupling in flow chamber 40, stream
First sewer pipe 21 of dynamic room 40 ensure that sheath fluid stability, the stability of the signal detection of particle analyzer using loop
Height, improves the CV value (discharge coefficient) of detection signal, and reduces the waiting time cleaned between test tube, improves instrument
Detection efficiency, meanwhile, waste liquid will not be pressed into flow chamber 40 by the positive pressure not dissipated completely also in the second sewer pipe 22, thus
Flow chamber 40 is avoided to pollute.
With continued reference to Fig. 1, in liquid channel system shown in FIG. 1, between the sheath fluid entrance 42a and sheath fluid bucket 10a of flow chamber 40a
Pipeline on be provided with sheath liquid filter 11a and sheath fluid buffer 12a, sheath liquid filter 11a is for being filtered sheath fluid, sheath
Liquid buffer 12a is used to eliminate the fluid pulsation in fluid path, guarantees stable sheath stream speed.Second existing for the liquid channel system
Defect is practice discovery sheath fluid buffer 12a positive pressure with higher, in fluid path maintenance, such as replacement sheath liquid filter 11a
When, the positive pressure of sheath fluid buffer 12a can extrude sheath fluid from sheath fluid buffer 12a, make troubles to fluid path maintenance, while sheath
The decline of pressure caused by liquid buffer 12a is safeguarded due to fluid path will affect the stability of sheath stream, the working efficiency of lowering apparatus.
For above-mentioned second defect, with continued reference to Fig. 2, in the liquid channel system of particle analyzer of the invention, sheath fluid enters
Mouthfuls 42 are connected to sheath fluid supplying module 10 by the first branch pipe 61, are disposed with sheath fluid along sheath fluid flow direction on the first branch pipe 61
Filter 11, check valve 13 and sheath fluid buffer 12, check valve 13 allow sheath fluid uniaxially to flow to sheath fluid from sheath liquid filter 11
Buffer 12, in fluid path maintenance, for example when replacement sheath liquid filter 11, check valve 13 can be prevented in sheath fluid buffer 12
Positive pressure extrudes sheath fluid, keeps the maintenance of liquid channel system more convenient, safe；Check valve 13 can keep sheath fluid buffer 12 simultaneously
In pressure, prevent fluid path safeguard when cause the pressure of sheath stream to decline, improve the working efficiency of instrument.The list of the present embodiment
The valve of sheath fluid one-way flow can be that by valve 13, include but is not limited to be mechanical structure formula check valve, solenoid valve or
Hand-operated valve, solenoid valve carries out the folding of valve by control system electric signal or hand-operated valve by manual operation, to realize list
The effect flowed to the unidirectionally controlled sheath fluid of valve 13.
Referring to Fig. 2, the first transfer tube P1 and first switch valve 71 are additionally provided on the first branch pipe 61, wherein the first driving
P1 is pumped on the first branch pipe 61 between sheath liquid filter 11 and sheath fluid supplying module 10, the first transfer tube P1 is used for sheath fluid
The sheath fluid of supplying module 10 is pumped to sheath liquid filter 11, and first switch valve 71 is located at sheath fluid buffer 12 and sheath fluid entrance 42
On first branch pipe 61, first switch valve 71 can be used for controlling the folding of the first branch pipe 61.
Referring to Fig. 2, sample entrance port 41 is connected to sampling needle 30 by the second branch pipe 62, is provided with the second drive on the second branch pipe 62
Dynamic pump P2, the second transfer tube P2 can be used for for the sample of sampling needle 30 being pumped to the sample entrance port 41 of flow chamber 40.Flow chamber 40
Also there is cleaning entrance 44, cleaning entrance 44 is connected to sheath fluid supplying module 10 by the second cleaning pipe 82, passes through the second branch pipe 62
It is connected to sampling needle 30, is provided with the second purge valve 74 in the second cleaning pipe 82, the second purge valve 74 can be used for controlling the second cleaning
The folding of pipe 82, after a completion of the sample, control the second transfer tube P2 reversion, sheath fluid supplying module 10 passes through the second cleaning pipe
82 supply sheath fluid to cleaning entrance 44, and enter the second branch pipe 62 and sampling needle 30 by cleaning entrance 44, are completed pair with this
The cleaning of the inner wall of second branch pipe 62 and sampling needle 30, prevents the remaining sample of the inner wall of sampling needle 30 to next to be collected
Sample pollutes, and improves the reliability of testing result, logical to the waste liquid after the inner wall washing of the second branch pipe 62 and sampling needle 30
Over cleaning module and the second sewer pipe 22 are expelled to waste liquid receiving module 20.
In Fig. 2, the first cleaning pipe 81 is connected to sheath fluid supplying module by third cleaning pipe 83 simultaneously with the second cleaning pipe 82
10, the first cleaning pipe 81 can connect third cleaning pipe 83 with the second cleaning pipe 82 by threeway, be provided in the first cleaning pipe 81
First purge valve 73 is provided with the 4th transfer tube P4, the folding of the first purge valve 73, the second purge valve 74 in third cleaning pipe 83
It can control by the way that whether the sheath fluid of the 4th transfer tube P4 pumping flows into the first cleaning pipe 81, the second cleaning pipe 82.
In Fig. 2, second switch valve 72 is additionally provided on the first sewer pipe 21, the first sewer pipe 21 passes through second switch valve 72
Folding control waste liquid whether be discharged, be provided with third transfer tube P3 on the second sewer pipe 22, third transfer tube P3 is for being sucked out
Waste liquid in service sink 50 is simultaneously expelled to waste liquid receiving module 20 by the second sewer pipe 22.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is not considered as limiting the invention, those skilled in the art are not departing from the principle of the present invention and objective
In the case where, it can make changes, modifications, alterations, and variations to the above described embodiments in the range of invention, all these change
Change all should belong within the scope of protection of the claims of the present invention.
Claims (10)
1. a kind of liquid channel system of particle analyzer characterized by comprising
Sheath fluid supplying module, for supplying sheath fluid；
Waste liquid receiving module, for receiving waste liquid；
Sample-feed module, including sampling needle, for acquiring and supplying sample；
Flow chamber, for sweeping along sample to flow through for sheath fluid, there is the flow chamber sample entrance port, sheath fluid entrance and waste liquid to go out
Mouthful, the sample entrance port is connected to sampling needle, and the sheath fluid entrance is connected to sheath fluid supplying module, and the waste liquid outlet is useless by first
Liquid pipe is connected to waste liquid receiving module；
Cleaning module, the cleaning module are connected to sheath fluid supplying module by the first cleaning pipe and are carried out clearly with the outer wall to sampling needle
It washes, the cleaning module is connected to waste liquid receiving module by the second sewer pipe and is received so that the waste liquid of cleaning module is expelled to waste liquid
Module.
2. the liquid channel system of particle analyzer according to claim 1, which is characterized in that the sheath fluid entrance passes through first
Pipe is connected to sheath fluid supplying module, on first branch pipe along sheath fluid flow direction be disposed with sheath liquid filter, check valve and
Sheath fluid buffer.
3. the liquid channel system of particle analyzer according to claim 2, which is characterized in that be additionally provided on first branch pipe
First transfer tube and first switch valve, first between sheath liquid filter and sheath fluid supplying module of first transfer tube
Guan Shang, the first switch valve are located on the first branch pipe of sheath fluid buffer and sheath fluid entrance.
4. the liquid channel system of particle analyzer according to claim 1, which is characterized in that the sample entrance port passes through second
Pipe is connected to sampling needle, is provided with the second transfer tube on second branch pipe.
5. the liquid channel system of particle analyzer according to claim 4, which is characterized in that the flow chamber also have clean into
Mouthful, the cleaning entrance is connected to sheath fluid supplying module by the second cleaning pipe, is connected to sampling needle by the second branch pipe, and described second
The second purge valve is provided in cleaning pipe.
6. the liquid channel system of particle analyzer according to claim 5, which is characterized in that first cleaning pipe and second is clearly
It washes pipe while passing through third cleaning pipe connection sheath fluid supplying module, be provided with the first purge valve in first cleaning pipe, it is described
The 4th transfer tube is provided in third cleaning pipe.
7. the liquid channel system of particle analyzer according to claim 1, which is characterized in that be provided on first sewer pipe
Second switch valve is provided with third transfer tube on second sewer pipe.
8. the liquid channel system of particle analyzer according to claim 1, which is characterized in that the cleaning module includes cleaning
Service sink is accessed on pond, the top in the first cleaning pipe self-cleaning pond, and the lower part access in the second sewer pipe self-cleaning pond is clear
Wash pool.
9. a kind of particle analyzer, which is characterized in that the particle analyzer includes grain described in claim 1 to 8 any one
The liquid channel system of sub- analyzer.
10. a kind of discharging of waste liquid method of particle analyzer, which is characterized in that the particle analyzer includes that waste liquid receives mould
Block, flow chamber and cleaning module, the flow chamber have sample entrance port, sheath fluid entrance and waste liquid outlet, and the waste liquid outlet is logical
The first sewer pipe connection waste liquid receiving module is crossed, the waste liquid of flow chamber is individually expelled to by waste liquid by the first sewer pipe and is received
Module, the cleaning module are connected to waste liquid receiving module by the second sewer pipe, pass through the second sewer pipe giving up cleaning module
Liquid is individually expelled to waste liquid receiving module.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811605399.0A CN109444028A (en) | 2018-12-26 | 2018-12-26 | A kind of particle analyzer and its liquid channel system, discharging of waste liquid method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811605399.0A CN109444028A (en) | 2018-12-26 | 2018-12-26 | A kind of particle analyzer and its liquid channel system, discharging of waste liquid method |
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Cited By (7)
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| CN110118717A (en) * | 2019-05-28 | 2019-08-13 | 北京唯公医疗技术有限公司 | The liquid channel system and its application method and flow cytometer of flow cytometer |
| CN110118718A (en) * | 2019-05-28 | 2019-08-13 | 深圳唯公生物科技有限公司 | Liquid fluid system, test method, the regulation method of negative pressure device and flow cytometer |
| CN112858661A (en) * | 2019-11-28 | 2021-05-28 | 深圳市帝迈生物技术有限公司 | Sample detection system and sample analyzer |
| CN113125330A (en) * | 2021-03-29 | 2021-07-16 | 深圳市科曼医疗设备有限公司 | Flow cytometry |
| CN113390845A (en) * | 2021-06-17 | 2021-09-14 | 杭州深度生物科技有限公司 | Flow type fluorescence detection liquid path system |
| CN114062226A (en) * | 2020-07-31 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Liquid path device and sample analyzer |
| CN114160529A (en) * | 2021-10-29 | 2022-03-11 | 常州必达科生物科技有限公司 | Flow-type pool cleaning system and method |
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