CN110007102A - A kind of liquid relief accurate quantification sampling device - Google Patents
A kind of liquid relief accurate quantification sampling device Download PDFInfo
- Publication number
- CN110007102A CN110007102A CN201910261836.XA CN201910261836A CN110007102A CN 110007102 A CN110007102 A CN 110007102A CN 201910261836 A CN201910261836 A CN 201910261836A CN 110007102 A CN110007102 A CN 110007102A
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- Prior art keywords
- intake passage
- valve
- liquid relief
- sample intake
- pump
- Prior art date
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Links
- 239000007788 liquid Substances 0.000 title claims abstract description 93
- 238000011002 quantification Methods 0.000 title claims abstract description 29
- 238000005070 sampling Methods 0.000 title claims abstract description 15
- 239000012530 fluid Substances 0.000 claims abstract description 14
- 238000005086 pumping Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 description 18
- 238000002347 injection Methods 0.000 description 12
- 239000007924 injection Substances 0.000 description 12
- 238000004140 cleaning Methods 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000000284 extract Substances 0.000 description 5
- 230000005484 gravity Effects 0.000 description 5
- 238000000605 extraction Methods 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000001514 detection method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000002000 scavenging effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000005622 photoelectricity Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of liquid relief accurate quantification sampling devices, pipette including having exhaust outlet and leakage fluid dram, the pump of energy positive and negative rotation, it is able to achieve the multichannel valve group of different liquids sample introduction, connect the connecting tube of pipette exhaust outlet and pump, the two-position three-way valve of connection resolution reactor and multichannel valve group, judge photoelectric detector whether drain, control the valve of draining switch, separator tube between pipette and pump, judge the photoelectric detector of exhaust outlet liquid on-off, and the control module of each module associated working of automation control, the convergent point for the multichannel valve group being connected with two-position three-way valve normal-closed end.
Description
Technical field
The present invention relates to liquid relief accurate quantification technical field, specially a kind of liquid relief accurate quantification sampling device.
Background technique
It combines, stablize and accurate liquid relief is quantitative in the automation that technique of analytical chemistry and instrument and meter combine
Technical method and system, as the extension application of lab analysis, such as in-line analyzer.
Online analyzer does not all take this chemical laboratory pipette that is equal to operate sample introduction currently on the market
Liquid relief quantitative sample injection method and system, traditional photoelectric metering are easy to be influenced by water sample turbidity, greasy dirt, crystallization and coloration, together
When multiple-way valve be easy by itself dead volume and liquid leakage to be caused reagent contamination and error, Traditional photovoltaic metered rate is time-consuming slowly
It is long, so that this input mode brings biggish inconvenience to product.
Summary of the invention
The purpose of the present invention is to provide a kind of liquid relief accurate quantification sampling devices, to solve to propose in above-mentioned background technique
Problem.
To achieve the above object, the invention provides the following technical scheme:
A kind of liquid relief accurate quantification sampling device, pump, energy including pipette, energy positive and negative rotation with exhaust outlet and leakage fluid dram are real
Multichannel valve group, the connecting tube of connection pipette exhaust outlet and pump, connection resolution reactor and the multi-pass of existing different liquids sample introduction
The two-position three-way valve of road valve group, photoelectric detector whether judge drain, control draining switch valve, pipette and pump between
Separator tube, judge the control mould of the photoelectric detector of exhaust outlet liquid on-off and automation control each module associated working
The convergent point of block, the multichannel valve group being connected with two-position three-way valve normal-closed end.
Preferably, the multichannel valve group be communicated with the first sample intake passage, the second sample intake passage, third sample intake passage,
4th sample intake passage and the 5th sample intake passage.
The control module is connect with pump, detector, photoelectric detector, valve and two-position three-way valve respectively.
The output end of the pump is connect with separator tube.
First sample intake passage, the second sample intake passage, third sample intake passage, the 4th sample intake passage and the 5th sample intake passage
It is connect with convergent point.
The input terminal of the output end of the photoelectric detector and detector connects, the output end of the detector and two three
The signal end of port valve connects.
The output end of the photoelectric detector and the signal end of valve connect.
This liquid relief accurate quantification sample injection method and system are completed pair as the module or component part of in-line analyzer
Water sample, amount mark, zero standard, pure water, reagent liquid relief sample introduction avoid cross contamination for the operation of chemical laboratory pipette, can be into
Liquid relief rinse before row liquid relief sample introduction, can also carry out liquid relief cleaning operation, while can pass through water sample, amount mark and pure water or zero standard
Different liquid relief number of injections ratios improve the live work of water quality online analyzer to realize to the different extension rates of water sample to be measured
Condition adaptability improves the range ability of in-line analyzer.
Detailed description of the invention
Fig. 1 is positive structure schematic of the present invention;
In figure: 1- pipette, 2- pump, the first sample intake passage of 31-, the second sample intake passage of 32-, 33- third sample intake passage, 34- the
Four sample intake passages, the 5th sample intake passage of 35-, 4- two-position three-way valve, 5- photoelectric detector, 6- valve, 7- control module, 8- buffering
Pipe, 9- detector, 10- convergent point.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that, term " on ", "lower", "front", "rear", "left", "right", "top",
The orientation or positional relationship of the instructions such as "bottom", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, merely to just
In description the present invention and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with
Specific orientation construction and operation, therefore be not considered as limiting the invention.
Referring to Fig. 1, the present invention provides a kind of technical solution: a kind of liquid relief accurate quantification sampling device, including with row
The pipette 1 of port and leakage fluid dram, the pump 2 of energy positive and negative rotation, the multichannel valve group for being able to achieve different liquids sample introduction, connection pipette
The connecting tube of exhaust outlet and pump, the two-position three-way valve 4 of connection resolution reactor and multichannel valve group, photoelectricity whether judge drain
Detector 5, the detection for controlling separator tube 8 between the valve 6 of draining switch, pipette and pump, judging exhaust outlet liquid on-off
Device 9 and the control module 7 of automation control each module associated working, the multiple valve being connected with 4 normal-closed end of two-position three-way valve
The convergent point 10 of group.
Multichannel valve group is communicated with the first sample intake passage 31, the second sample intake passage 32, third sample intake passage 33, the 4th sample introduction
Channel 34 and the 5th sample intake passage 36.
Control module 7 is connect with pump 2, detector 9, photoelectric detector 5, valve 6 and two-position three-way valve 4 respectively.
The output end of pump 2 is connect with separator tube 8.
First sample intake passage 31, the second sample intake passage 32, third sample intake passage 33, the 4th sample intake passage 34 and the 5th sample introduction
Channel 36 is connect with convergent point 10.
The output end of photoelectric detector 5 is connect with the input terminal of detector 9, the output end and two-position three-way valve 4 of detector 9
Signal end connection.
The output end of photoelectric detector 5 is connect with the signal end of valve 6
A kind of liquid relief rinse process of liquid relief accurate quantification sample injection method and system, liquid relief rinse operation are to extract respectively in two steps
Quantitative, extraction drain, extracts and quantitatively passes through 7 control valve of control module by above-mentioned liquid relief accurate quantification sample injection method and system
6 open, and 4 normal-closed end of two-position three-way valve is opened, and close valve 6, and pump 2 rotates clockwise, and liquid will be passed through the by negative pressure absorbing
One sample intake passage 31, the second sample intake passage 32, third sample intake passage 33, the 4th sample intake passage 34, the 5th sample intake passage 35, two
Triple valve 4, into pipette, liquid flooding goes out pipette and will enter leakage fluid dram by gravity to be detected by photoelectric detector 5, i.e.,
It completes to extract quantification steps, extracts drain and opened by the way that the closing of multichannel valve group 3a valve is switched to valve 6 immediately, the second sample introduction is logical
Road 32 connects air, and liquid continues overflow and goes out pipette and enter separator tube by detector 9, when detector 9 detects liquid
After pipeline no liquid, while opening valve 6, pump 2 rotate clockwise, and liquid passes through separator tube 8, detector 9, photoelectric detector 5, valve
Door 6 empties, and until detector 9, detector 9 can't detect liquid, stopping pump 2 is completed to extract drain step, realizes liquid relief
Rinse operation.
The operation of liquid relief accurate quantification sampling device liquid relief sample introduction is to extract quantitative, liquid relief sample introduction respectively in two steps, and it is fixed to extract
Amount controls 4 normal-closed end of two-position three-way valve by control module 7 by above-mentioned liquid relief accurate quantification sample injection method and system and opens, and closes
Valve closing door 6, pump 2 rotate clockwise, and liquid will be by negative pressure absorbing by the first sample intake passage 31, the second sample intake passage 32, the
Three sample intake passages 33, the 4th sample intake passage 34, the 5th sample intake passage 35, two-position three-way valve 4, into pipette, liquid flooding goes out
Pipette will be entered leakage fluid dram by gravity and be detected by photoelectric detector 5, that is, complete to extract quantification steps, liquid relief sample introduction passes through
Pump 2 is stopped immediately, while two-position three-way valve 4 is switched to normally open end connection, valve 6 is opened, by gravity by pipette liquid
Body enters resolution reaction tank by normally open end to 4 common end of two-position three-way valve by 1 low side of pipette, i.e. completion liquid relief sample introduction step
Suddenly, the accurate sample introduction operation of liquid relief is realized.
A kind of liquid relief cleaning process of liquid relief accurate quantification sample injection method and system, three steps of liquid relief cleaning operation point are respectively
It extracts quantitative, extraction cleaning, extract drain, extraction quantitatively passes through control by above-mentioned liquid relief accurate quantification sample injection method and system
7 control valve 6(of module such as connects pure water) it opens, 4 normally open end of two-position three-way valve is opened, and valve 6 is closed, and pump 2 rotates clockwise,
It extracts cleaning to continue to rotate clockwise by pump 2, photoelectric detector 5 detects, continues certain scavenging period, that is, completes to extract clear
Step is washed, liquid continues overflow and goes out pipette and enter by photoelectric detector 5,4 normally open end of two-position three-way valve to common end slow
Washing pipe, after photoelectric detector 5 detects liquid line no liquid, pump 2 is rotated counterclockwise, and liquid passes through separator tube 8, two three
Port valve 4,1 exhaust outlet of pipette and photoelectric detector 5,1 leakage fluid dram of pipette and photoelectric detector 5, valve 6 empty, Zhi Daoguang
Photodetector 5, photoelectric detector 5 can't detect liquid, stop pump 2, that is, complete to extract drain step, realize liquid relief cleaning behaviour
Make, the scavenging period can set control.
The cloche of above-mentioned liquid relief accurate quantification sample injection method and the pipette 1 of system includes that exhaust outlet (is arranged on cloche
Port passes through photoelectric detector 5), leakage fluid dram (under cloche leakage fluid dram pass through photoelectric detector 5), in vertical direction, drain
Mouth is lower than exhaust outlet, and exhaust outlet is lower than the overflow top of pipette 1, and when pumping 2 main story clockwise, liquid overflows from pipette 1
The outflow of stream top will not be encountered at the top of cloche.When pump 2 continues to rotate forward clockwise, flowed out from the overflow top of pipette 1
Liquid due to 6 closing liquid of valve due to gravity fill up leakage fluid dram space can by the exhaust outlet of pipette 1, two-position three-way valve 4,
The persistently discharge of separator tube 8, pump 2.When pump reversion counterclockwise, when valve 6 is opened, pass through two-position three-way valve 4 from the liquid of separator tube
The overflow top of pipette 1 will not be entered but under process by entering cloche by 1 exhaust outlet of pipette and upper photoelectric detector 5
Photoelectric detector 5 enters leakage fluid dram, valve 6 is discharged.
Leakage fluid dram can also be used to realize discharge in the cleaning of the liquid relief of a kind of above-mentioned liquid relief accurate quantification sample injection method and system
Waste liquid is cleaned, liquid relief cleaning operation is also that two steps are completed to be to extract quantitative, extraction drain, i.e., a kind of shifting respectively with liquid relief rinse
Liquid accurate quantification sample injection method and the liquid relief cleaning operation of system pass through 7 control valve 6(of control module and such as connect pure water) it opens,
4 normally open end of two-position three-way valve is opened, and valve 6 is closed, and pump 2 rotates clockwise, and into pipette 1, liquid flooding goes out pipette 1 will
Enter leakage fluid dram by gravity to be detected by photoelectric detector 5, that is, completes to extract quantification steps, liquid continues overflow and goes out pipette
1, then enter separator tube to common end by the exhaust outlet of pipette 1, by photoelectric detector 5,4 normally open end of two-position three-way valve
8, after photoelectric detector 5 detects liquid line no liquid, 3b valve, opening valve 6 are simultaneously closed off, pump 2 rotates counterclockwise, liquid
From separator tube 8, two-position three-way valve 4, the exhaust outlet of pipette 1 and photoelectric detector 5, the leakage fluid dram of pipette 1 and Photoelectric Detection
Device 5, valve 6 empty, and until photoelectric detector 5, photoelectric detector 5 can't detect liquid, stopping pump 2 is completed to extract drain
Step realizes liquid relief cleaning operation.The liquid relief cleaning operation, which executes number, can set control wash number.
Liquid and valve 6 emptying that a kind of above-mentioned liquid relief accurate quantification sample injection method and the pump 2 of system empty clockwise
The combinable collection of liquid and the collection that selectivity is carried out by two-position three-way valve, have reduced the generation for needing harmless treatment waste liquid
Amount, the waste liquid that liquid relief rinse and liquid relief are cleaned merge collection part can direct emission environment, by the reagent waste liquid of liquid relief sample introduction
Carry out harmless treatment is collected separately.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (7)
1. a kind of liquid relief accurate quantification sampling device, it is characterised in that: including with exhaust outlet and leakage fluid dram pipette (1),
It can the pump (2) of positive and negative rotation, the multichannel valve group for being able to achieve different liquids sample introduction, connection pipette (1) exhaust outlet and the company for pumping (2)
Adapter tube, the photoelectric detector (5) whether judge drain, is controlled the two-position three-way valve (4) of connection resolution reactor and multichannel valve group
Separator tube (8) between the valve (6) of draining switch processed, pipette and pump (2), the detector for judging exhaust outlet liquid on-off
(9) and the control module (7) of automation control each module associated working, the multi-pass that is connected with two-position three-way valve (4) normal-closed end
The convergent point (10) of road valve group.
2. a kind of liquid relief accurate quantification sampling device according to claim 1, it is characterised in that: the multichannel valve group connects
It is connected with the first sample intake passage (31), the second sample intake passage (32), third sample intake passage (33), the 4th sample intake passage (34) and the 5th
Sample intake passage (36).
3. a kind of liquid relief accurate quantification sampling device according to claim 1, it is characterised in that: the control module (7)
It is connect respectively with pump (2), detector (9), photoelectric detector (5), valve (6) and two-position three-way valve (4).
4. a kind of liquid relief accurate quantification sampling device according to claim 1, it is characterised in that: the output of the pump (2)
End is connect with separator tube (8).
5. a kind of liquid relief accurate quantification sampling device according to claim 2, it is characterised in that: first sample intake passage
(31), the second sample intake passage (32), third sample intake passage (33), the 4th sample intake passage (34) and the 5th sample intake passage (36) with
Convergent point (10) connection.
6. a kind of liquid relief accurate quantification sampling device according to claim 1, it is characterised in that: the photoelectric detector
(5) output end is connect with the input terminal of detector (9), the output end of the detector (9) and the signal of two-position three-way valve (4)
End connection.
7. a kind of liquid relief accurate quantification sampling device according to claim 1, it is characterised in that: the photoelectric detector
(5) output end is connect with the signal end of valve (6).
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CN201910261836.XA CN110007102A (en) | 2019-04-02 | 2019-04-02 | A kind of liquid relief accurate quantification sampling device |
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CN201910261836.XA CN110007102A (en) | 2019-04-02 | 2019-04-02 | A kind of liquid relief accurate quantification sampling device |
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CN110007102A true CN110007102A (en) | 2019-07-12 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111579733A (en) * | 2020-05-26 | 2020-08-25 | 朱闪闪 | Liquid transfer device for food detection |
CN115427149A (en) * | 2020-02-28 | 2022-12-02 | 珀金埃尔默健康科学有限公司 | Multiplex polymerase chain reaction in a micropipette format |
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