CN114062226B - Liquid path device and sample analyzer - Google Patents
Liquid path device and sample analyzer Download PDFInfo
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- CN114062226B CN114062226B CN202010763165.XA CN202010763165A CN114062226B CN 114062226 B CN114062226 B CN 114062226B CN 202010763165 A CN202010763165 A CN 202010763165A CN 114062226 B CN114062226 B CN 114062226B
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- 239000007788 liquid Substances 0.000 title claims abstract description 484
- 239000002699 waste material Substances 0.000 claims abstract description 229
- 238000004140 cleaning Methods 0.000 claims abstract description 100
- 238000007599 discharging Methods 0.000 claims abstract description 9
- 239000012530 fluid Substances 0.000 claims description 43
- 239000010808 liquid waste Substances 0.000 claims description 11
- 238000001514 detection method Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 description 6
- 230000032683 aging Effects 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 4
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000003749 cleanliness Effects 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000008358 core component Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D1/00—Pipe-line systems
- F17D1/08—Pipe-line systems for liquids or viscous products
- F17D1/14—Conveying liquids or viscous products by pumping
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- Food Science & Technology (AREA)
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- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The application discloses a liquid path device and a sample analysis device. The liquid path device comprises: the first waste liquid tank is used for collecting primary cleaning waste liquid for cleaning the pipeline for the first time; the second waste liquid tank is used for collecting secondary cleaning waste liquid for performing second cleaning on the pipeline subjected to the first cleaning; the liquid discharging assembly is respectively communicated with the first waste liquid tank and the second waste liquid tank and is used for guiding liquid to the outside; the first reaction tank is communicated with the liquid discharge assembly; after the first reaction tank is discharged to the outside through the liquid discharge assembly, the primary cleaning waste liquid collected in the first waste liquid tank and the secondary cleaning waste liquid collected in the second waste liquid tank are sequentially discharged to the outside through the liquid discharge assembly, so that the liquid discharge assembly is cleaned successively. Through the mode, the risk that parts such as a liquid valve or a liquid pump in a liquid discharging assembly used for complex working conditions are aged or blocked can be reduced, meanwhile, the utilization rate of cleaning liquid is improved, and the cleaning cost is relatively reduced.
Description
Technical Field
The present disclosure relates to the field of sample analysis technologies, and in particular, to a liquid path device and a sample analysis device.
Background
Common faults of the current sample analysis technology are generally concentrated on liquid pumps and liquid valves, particularly liquid pumps and liquid valves for discharging waste liquid, and the liquid waste containing a blood sample is discharged, so that the membrane of the pump valve is easy to age or block.
The existing solution liquid pump valve is often used for flushing the liquid pump and the liquid valve for discharging the waste liquid for many times by adopting a large amount of clean liquid because of aging or blockage of the waste liquid discharge, such as diluent or cleaning liquid, so as to avoid the residual of the waste liquid after liquid discharge.
Disclosure of Invention
The application mainly provides a liquid way device and sample analysis device to solve the higher problem of cost in clean waste liquid highway section of arranging in the road device at night.
In order to solve the technical problems, one technical scheme adopted by the application is as follows: a liquid path apparatus is provided. The liquid path device comprises: the first waste liquid tank is used for collecting primary cleaning waste liquid for cleaning the pipeline for the first time; the second waste liquid tank is used for collecting secondary cleaning waste liquid for performing second cleaning on the pipeline subjected to the first cleaning; the liquid discharging assembly is respectively communicated with the first waste liquid tank and the second waste liquid tank and is used for guiding liquid to the outside; the first reaction tank is communicated with the liquid discharge assembly; after the first reaction tank is discharged to the outside through the liquid discharge assembly, the primary cleaning waste liquid collected in the first waste liquid tank and the secondary cleaning waste liquid collected in the second waste liquid tank are sequentially discharged to the outside through the liquid discharge assembly, so that the liquid discharge assembly is cleaned successively.
In some embodiments, the fluid path apparatus further comprises a first fluid conducting fluid path and a flow chamber communicating the first and second fluid waste tanks through the first fluid conducting fluid path;
and after counting, cleaning liquid for cleaning the flow chamber is respectively led to the first waste liquid tank and the second waste liquid tank through the first liquid guide liquid path.
In some embodiments, the liquid path device further comprises a second liquid guide pipe, the first reaction tank is communicated with the liquid discharge assembly and the second liquid waste tank through the second liquid guide pipe, and the secondary cleaning waste liquid for performing the second cleaning on the first reaction tank is collected in the second liquid waste tank.
In some embodiments, the liquid path device further comprises a second reaction tank and a third liquid guide liquid path, the second reaction tank is communicated with the liquid discharge assembly, and residual liquid in the second reaction tank is discharged to the outside through the liquid discharge assembly; the second reaction tank is connected with the first waste liquid tank and the second waste liquid tank through the third liquid guide liquid path;
and cleaning liquid for cleaning the second reaction tank is respectively guided to the first waste liquid tank and the second waste liquid tank through the liquid guide component.
In some embodiments, the liquid path device further comprises a fourth liquid guide liquid path, the second reaction tank comprises a front tank and a rear tank, the front tank is communicated with the rear tank through a counting hole, and counting detection is performed when liquid in the front tank enters the rear tank through the counting hole;
the rear tank is connected with the first waste liquid tank and the second waste liquid tank through the third liquid guide pipeline, the front tank is communicated with the liquid discharge assembly and the second waste liquid tank through the fourth liquid guide pipeline, and secondary cleaning waste liquid for carrying out secondary cleaning on the front tank is collected in the second waste liquid tank.
In some embodiments, the first reaction tank communicates with the drain assembly through the first waste tank; the drain assembly includes:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank, and the public end of the first three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first reaction tank, the first waste liquid tank and the second waste liquid tank to flow through the first three-way valve and be discharged to the outside.
In some embodiments, the drain assembly comprises:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank;
the normally-closed end of the second three-way valve is communicated with the public end of the first three-way valve, the normally-open end of the second three-way valve is communicated with the first reaction tank, and the public end of the second three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first reaction tank to flow through the second three-way valve and be discharged to the outside, and enabling liquid in the first waste liquid tank and the second waste liquid tank to flow through the first three-way valve and the second three-way valve and be discharged to the outside.
In some embodiments, the drain assembly comprises:
the first liquid draining path is used for sequentially draining the liquid in the first liquid waste tank and the liquid in the second liquid waste tank to the outside;
and the second liquid draining path is used for draining the liquid in the first reaction tank and the liquid in the second waste liquid tank to the outside.
In some embodiments, the first liquid discharge path includes:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank, and the public end of the first three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first waste liquid tank and liquid in the second waste liquid tank to flow through the first three-way valve in sequence and be discharged to the outside.
In some embodiments, the second liquid discharge path includes:
a second driving member;
the normally closed end of the second three-way valve is communicated with the first reaction tank, and the public end of the second three-way valve is connected with the second driving piece;
the second two-way valve is communicated with the second waste liquid tank and the normally open end of the second three-way valve;
the second driving piece is used for providing power to enable liquid in the first reaction tank and the second waste liquid tank to flow through the second three-way valve in sequence and be discharged to the outside.
In order to solve the technical problems, another technical scheme adopted by the application is as follows: a sample analysis device is provided. The sample analysis device comprises a liquid path device as described above.
The beneficial effects of this application are: unlike the prior art, the present application discloses a fluid path device and a sample analysis device. Through setting up first waste liquid jar and second waste liquid jar to collect respectively and carry out the primary waste liquid of wasing and carry out the secondary waste liquid of wasing to the pipeline after the first time washs, and set up the flowing back subassembly and be connected with first waste liquid jar, second waste liquid jar and first reaction tank, make the first reaction tank pass through the flowing back subassembly and discharge raffinate to outside after, the primary waste liquid of wasing that collects in the first waste liquid jar and the secondary waste liquid of wasing that collects in the second waste liquid jar pass through the flowing back subassembly in proper order and discharge to the outside of night circuit device, with wasing the flowing back subassembly in succession, clear away the residue in the flowing back subassembly, and then reduce the part such as liquid valve or the liquid pump that is arranged in the flowing back subassembly of more complicated operating mode and take place ageing or jam risk, still improved the utilization ratio of washing liquid simultaneously, cleaning cost has been reduced relatively.
Drawings
For a clearer description of embodiments of the present application or of the solutions of the prior art, the drawings that are required to be used in the description of the embodiments or of the prior art will be briefly described, it being apparent that the drawings in the description below are only some embodiments of the present application, and that other drawings may be obtained, without inventive effort, by a person skilled in the art from these drawings, in which:
FIG. 1 is a schematic view of an embodiment of a liquid path apparatus provided in the present application;
FIG. 2 is a schematic view of another embodiment of a fluid path set provided herein;
fig. 3 is a schematic structural view of another embodiment of a liquid path device provided in the present application.
Detailed Description
The following description of the technical solutions in the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings in the embodiments of the present application, and it is apparent that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be made by one of ordinary skill in the art without undue burden from the present disclosure, are within the scope of the present disclosure.
The terms "first," "second," "third," and the like in the embodiments of the present application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", and "a third" may explicitly or implicitly include at least one such feature. In the description of the present application, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise. Furthermore, the terms "comprise" and "have," as well as any variations thereof, are intended to cover a non-exclusive inclusion. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those listed steps or elements but may include other steps or elements not listed or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the present application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a liquid path device provided in the present application.
The fluid path set 100 generally includes a first reaction cell 10, a flow chamber 12, a sample pushing assembly 14, a first positive pressure fluid source 16, a first fluid conducting fluid path 18, a second reaction cell 20, a second positive pressure fluid source 22, a third fluid conducting fluid path 24, a first waste fluid tank 26, a second waste fluid tank 28, and a fluid discharge assembly 30.
The flow chamber 12 connects the first waste liquid tank 26 and the second waste liquid tank 28 through the first liquid guiding liquid path 18 to guide the liquid in the flow chamber 12 to the first waste liquid tank 26 or the second waste liquid tank 28 through the first liquid guiding liquid path 18; the sample pushing component 14 is used for injecting the liquid in the first reaction tank 10 into the flow chamber 12 to form sheath liquid in the flow chamber 12 so as to perform counting detection; the first positive pressure liquid source 16 is connected to the flow chamber 12, and is configured to input a cleaning liquid into the flow chamber 12 after counting is completed, so as to clean the flow chamber 12 and the first liquid guide path 18. Wherein, the primary cleaning waste liquid formed after the first cleaning of the flow chamber 12 and the first liquid guiding liquid path 18 is collected in the first waste liquid tank 26; after the first cleaning of the flow chamber 12 and the first liquid guide path 18, the secondary cleaning waste liquid formed by the second cleaning of the flow chamber 12 and the first liquid guide path 18 is collected in the second waste liquid tank 28.
The sample pushing assembly 14 may include a syringe and a sampling needle, the syringe driving the sampling needle to obtain a sample fluid from the first reaction cell 10 and place the sample fluid into the flow chamber 12 to form a sheath fluid; the sample pushing assembly 14 may further comprise a liquid pump and a conduit along which the liquid pump drives the sample liquid in the first reaction cell 10 into the flow chamber.
In this embodiment, the first liquid guiding path 18 includes a three-way valve 180 and a two-way valve 182, the two-way valve 182 is connected to the common end of the flow chamber 12 and the three-way valve 180, the normally open end of the three-way valve 180 is connected to the first waste liquid tank 26, and the normally closed end of the three-way valve 180 is connected to the second waste liquid tank 28. The two-way valve 182 is a normally open two-way valve, so as to isolate the flow chamber 12 from the first waste liquid tank 26 and the second waste liquid tank 28 when the flow chamber 12 is not in use, and prevent waste liquid in the first waste liquid tank 26 and the second waste liquid tank 28 from evaporating and escaping to the flow chamber 12, so that the flow chamber 12 and a part of the first liquid guide night path 18 communicated with the flow chamber 12 are polluted.
At the time of counting detection, the two-way valve 182 is conducted, so that the flow chamber 12 is connected to the first waste liquid tank 26 to collect the sheath liquid after counting detection in the first waste liquid tank 26; after the counting test is completed, the first positive pressure liquid source 16 injects the cleaning liquid into the flow chamber 12.
In other embodiments, the first liquid guiding night channel 18 may further include a three-way pipe and two-way valves, which is not limited in this application.
The above-mentioned flow chamber 12 and first liquid-guiding liquid path 18 for counting and detecting need to have high cleanliness and weak contamination resistance, and once the flow chamber 12 and first liquid-guiding liquid path 18 are contaminated, the counting result is affected, so that it needs to be cleaned multiple times and in large quantity after the counting and detecting is completed, so as to ensure no residue of sample, reagent and bubbles, and thus a large amount of cleaning liquid needs to be consumed.
During the first cleaning, the cleaning liquid washes the flow chamber 12 and the first liquid guide liquid path 18 to wash away most sample liquid, reagent liquid and the like stained on the flow chamber 12 and the first liquid guide liquid path 18, so as to form a primary cleaning waste liquid, wherein the primary cleaning waste liquid contains more sample content and reagent content; after the first cleaning, the sample content and the reagent content in the secondary cleaning waste liquid formed by the second cleaning flow chamber 12 and the first liquid guiding liquid path 18 are greatly reduced, and after the flow chamber 12 and the first liquid guiding liquid path 18 are thoroughly cleaned, a large amount of secondary cleaning waste liquid is collected in the second waste liquid tank 28, so that the relatively clean secondary cleaning waste liquid can be utilized to clean the waste liquid pipeline and the like, the utilization rate of the cleaning liquid is improved, and the cost of the cleaning liquid is relatively reduced.
Further, the liquid path apparatus 100 further includes a second liquid guide pipe 19, the first reaction tank 10 is communicated with the liquid discharge assembly 30 and the second liquid waste tank 28 through the second liquid guide pipe 19, the sample residual liquid and the like in the first reaction tank 10 and the primary cleaning waste liquid for the first cleaning of the first reaction tank 10 are discharged to the outside through the liquid discharge assembly 30 through the second liquid guide pipe 19, and the secondary cleaning waste liquid for the second cleaning of the first reaction tank 10 is collected in the second liquid waste tank 28 so as to clean the liquid discharge assembly 30 in the process of using the secondary cleaning waste liquid to be discharged to the outside through the liquid discharge assembly 30.
The second liquid guiding pipeline 19 comprises a three-way pipe and two-way valves, one end of the three-way pipe is communicated with the first reaction tank 10, the other two ends of the three-way pipe are respectively connected with the two-way valves, and the other ends of the two-way valves are respectively communicated with the first waste liquid tank 26 and the second waste liquid tank 28. The second catheter line 19 may also be of the same construction as the first catheter line 18.
The second reaction tank 20 is connected with a first waste liquid tank 26 and a second waste liquid tank 28 through a third liquid guide liquid path 24 so as to guide the liquid in the second reaction tank 20 to the first waste liquid tank 26 or the second waste liquid tank 28 through the third liquid guide liquid path 24; the second positive pressure liquid source 22 is connected to the second reaction tank 20, and is used for injecting a cleaning liquid into the second reaction tank 20 to clean the second reaction tank 20 and the third liquid guide liquid path 24. Wherein, the primary cleaning waste liquid formed after the first cleaning is carried out on the second reaction tank 20 and the third liquid guide liquid path 24 is collected in the first waste liquid tank 26; after the first cleaning of the reaction tank 20 and the third liquid guide passage 24, the secondary cleaning waste liquid formed by the second cleaning of the reaction tank 20 and the third liquid guide passage 24 is collected in the second waste liquid tank 28.
In this embodiment, the third liquid guiding path 24 includes a three-way valve 240 and a two-way valve 242, the two-way valve 242 is connected to the common end of the second reaction tank 20 and the three-way valve 240, the normally open end of the three-way valve 240 is connected to the first waste liquid tank 26, and the normally closed end of the three-way valve 240 is connected to the second waste liquid tank 28. The two-way valve 242 is a normally open two-way valve, so as to isolate the second reaction tank 20 from the first waste liquid tank 26 and the second waste liquid tank 28 when the second reaction tank 20 is not in use, and prevent the waste liquid in the first waste liquid tank 26 and the second waste liquid tank 28 from evaporating and escaping to the second reaction tank 20, so that the second reaction tank 20 and a part of the third liquid guide liquid path 24 communicated with the second reaction tank 20 are polluted.
In other embodiments, the second liquid guiding night channel 24 may further include a three-way pipe and two-way valves, which is not limited in this application.
The second reaction tank 20 may be a reaction tank or a detection tank with high requirements for cleanliness and low contamination resistance, such as an impedance tank, and therefore requires multiple cleaning operations to clean the reaction tank, and consumes a large amount of cleaning liquid. Therefore, the primary cleaning waste liquid is collected in the first waste liquid tank 26, and the secondary cleaning waste liquid is collected in the second waste liquid tank 28, so that the secondary cleaning waste liquid is reused to clean the waste liquid pipeline and the like, the utilization rate of the cleaning liquid is improved, and the cost of the cleaning liquid is relatively reduced.
In this embodiment, the second reaction tank 20 is an impedance tank, and includes a front tank 201 and a rear tank 202, where the front tank 201 is communicated with the rear tank 202 through a counting hole (not shown), so as to perform counting detection when the liquid in the front tank 201 enters the rear tank 202 through the counting hole.
Specifically, the liquid path apparatus 100 further includes a fourth liquid guide pipe 25, the rear tank 202 is connected to the first waste liquid tank 26 and the second waste liquid tank 28 through the third liquid guide pipe 24, the front tank 201 is communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through the fourth liquid guide pipe 25, the sample residual liquid and the like in the front tank 201 and the primary cleaning waste liquid for cleaning the front tank 201 for the first time are discharged to the outside through the liquid discharge assembly 30 through the fourth liquid guide pipe 25, and the secondary cleaning waste liquid for cleaning the front tank 201 for the second time is collected in the second waste liquid tank 28 through the fourth liquid guide pipe 25.
The structure of the fourth catheter line 25 may be the same as that of the third catheter line 24, or the structure of the fourth catheter line 25 may be the same as that of the second catheter line 19.
The waste liquid collected in the first waste liquid tank 10 and the second waste liquid tank 20 may be from the first reaction tank 10, the flow chamber 12 and the second reaction tank 20, and may also be from waste liquid generated by cleaning other devices or pipes.
In this embodiment, the liquid draining assembly 30 is communicated with the first liquid draining tank 26 and the second liquid draining tank 28, wherein the first reaction tank 10 and the second reaction tank 20 drain residual sample liquid and the like through the liquid draining assembly 30, and the primary cleaning waste liquid collected in the first liquid draining tank 26 and the secondary cleaning waste liquid collected in the second liquid draining tank 28 are sequentially drained to the outside of the night-time device 100 through the liquid draining assembly 30, so as to clean the liquid draining assembly 30 successively, remove residues in the liquid draining assembly 30, and further facilitate reducing the risk of aging or blocking of the liquid draining assembly 30 for more complex working conditions.
In fig. 1, two first reaction tanks 10 are the same first reaction tank 10, and two first reaction tanks 201 are the same second reaction tank 20, so as to simplify the connection relationship between the first reaction tank 10 and the second reaction tank 20 and the liquid discharge assembly 30.
As shown in fig. 1, in the first embodiment, the first reaction tank 10 and the second reaction tank 20 are indirectly connected to the drain assembly 30 through the first waste liquid tank 26, in other words, the sample liquid, the reagent liquid, or the mixture thereof remaining after being used in the first reaction tank 10 and the second reaction tank 20 is collected to the first waste liquid tank 26 to be discharged to the outside through the drain assembly 30 through the first waste liquid tank 26.
Specifically, the first reaction tank 10 is respectively communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through the second liquid guide pipeline 19, the residual liquid in the first reaction tank 10 and the primary cleaning waste liquid generated by cleaning the first reaction tank 10 are collected in the first waste liquid tank 26, and the secondary cleaning waste liquid generated by cleaning the first reaction tank 10 is collected in the second waste liquid tank 28 so as to clean the liquid discharge assembly 30 for discharging the liquid in the first waste liquid tank 26 by using the secondary cleaning waste liquid. The front tank 201 in the second reaction tank 10 is respectively communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through a fourth liquid guide pipeline 25, and the rear tank 202 in the second reaction tank 10 is respectively communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through a third liquid guide pipeline 24.
Wherein, be provided with the two-way valve on the pipeline between first reaction tank 10 and the first waste liquid jar 26, be provided with the two-way valve on the pipeline between second reaction tank 20 and the first waste liquid jar 26, this two-way valve is used for controlling whether the corresponding reaction tank communicates first waste liquid jar 26.
The liquid draining assembly 30 generally comprises a first driving piece 31, a first three-way valve 32 and a first two-way valve 33, wherein the normally closed end of the first three-way valve 32 is communicated with the first waste liquid tank 26, the common end of the first three-way valve 32 is connected with the first driving piece 31, and the first two-way valve 33 is communicated with the second waste liquid tank 28 and the normally open end of the first three-way valve 32; wherein the first driving member 31 is configured to supply power to discharge the liquid in the first reaction tank 10, the first waste liquid tank 26, and the second waste liquid tank 28, respectively, to the outside through the first three-way valve 32.
In this embodiment, the first driving member 31 is a liquid pump, and each waste liquid is discharged to the outside through the first three-way valve 32 and the first driving member 31, so that the second cleaning waste liquid is utilized to clean the first three-way valve 32 and the first driving member 31, and the waste liquid impurities including blood samples and the like can be prevented from adhering to the core component, so that the aging speed of the membrane of the first three-way valve 32 is slowed down, the blockage of the first driving member 31 is avoided, the utilization rate of the cleaning liquid is improved, and the cleaning cost is relatively reduced.
The first driving member 31 may also be a gas source that provides negative pressure so that the liquid in the first reaction tank 10, the second reaction tank 20, the first waste liquid tank 26, and the second waste liquid tank 28 is discharged to the outside.
In fig. 2, two first reaction tanks 10 are the same first reaction tank 10, and two first reaction tanks 201 are the same second reaction tank 20, so as to simplify the connection relationship between the first reaction tank 10 and the second reaction tank 20 and the liquid discharge assembly 30.
In the second embodiment, as shown in fig. 2, the first reaction tank 10 and the second reaction tank 20 are directly connected to the drain assembly 30 to drain the residual liquid to the outside through the drain assembly 30.
In comparison with the first embodiment, the liquid discharge assembly 30 further includes a second three-way valve 34 disposed on a line communicating between the first three-way valve 32 and the first driving member 31, wherein a normally closed end of the second three-way valve 34 communicates with a common end of the first three-way valve 32, a normally open end of the second three-way valve 34 communicates with the first reaction tank 10, and a common end of the second three-way valve 34 is connected with the first driving member 31.
Wherein the first driving member 31 is configured to supply power such that the liquid in the first reaction tank 10 is discharged to the outside through the second three-way valve 34, and such that the liquid in the first and second waste liquid tanks 26 and 28 is discharged to the outside through the first and second three-way valves 32 and 34.
Specifically, two second three-way valves 34 are arranged on the pipeline between the first three-way valve 32 and the first driving piece 31, and normally closed ends of the two second three-way valves 34 are respectively communicated with the first reaction tank 10 and the second reaction tank 20.
As shown in fig. 2, the first reaction tank 10 is connected to the second waste liquid tank 28 and the normally-closed end of one second three-way valve 34 through the second liquid guide pipe 19, the front tank 201 in the second reaction tank 20 is connected to the second waste liquid tank 28 and the normally-closed end of the other second three-way valve 34 through the fourth liquid guide pipe 25, and the rear tank 202 in the second reaction tank 20 is communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through the third liquid guide pipe 24.
In fig. 3, two first reaction tanks 10 are the same first reaction tank 10, and two first reaction tanks 201 are the same second reaction tank 20, so as to simplify the connection relationship between the first reaction tank 10 and the second reaction tank 20 and the liquid discharge assembly 30.
As shown in fig. 3, in the third embodiment, the drain assembly 30 includes a first drain liquid channel 310 and a second drain liquid channel 320, where the first drain liquid channel 310 is used to drain the liquid in the first waste liquid tank 26 and the second waste liquid tank 28 to the outside in order to wash the first drain liquid channel 310 after the primary washing waste liquid is drained by using the secondary washing waste liquid in the second waste liquid tank 28; the second liquid discharge channel 320 is used for sequentially discharging the liquid in the first reaction tank 10 and the second liquid waste tank 28 to the outside, so as to clean the first liquid discharge channel 310 after the residual liquid in the first reaction tank 10 is discharged by using the secondary cleaning waste liquid in the second liquid waste tank 28.
The first liquid draining path 310 comprises a first driving piece 31, a first three-way valve 32 and a first two-way valve 33, wherein the normally closed end of the first three-way valve 32 is communicated with the first waste liquid tank 26, the common end of the first three-way valve 32 is connected with the first driving piece 31, and the first two-way valve 33 is communicated with the second waste liquid tank 28 and the normally open end of the first three-way valve 32; the first driving member 31 is configured to provide power to enable the liquid in the first waste liquid tank 26 and the liquid in the second waste liquid tank 28 to flow through the first three-way valve 32 in sequence and be discharged to the outside.
The second liquid draining path 320 comprises a second three-way valve 34, a second two-way valve 35 and a second driving piece 36, wherein the normally closed end of the second three-way valve 34 is communicated with the first reaction tank 10, the public end of the second three-way valve 34 is connected with the second driving piece 36, and the second two-way valve 35 is communicated with the second waste liquid tank 28 and the normally open end of the second three-way valve 34; wherein, the second driving member 36 is used for providing power to make the liquid in the first reaction tank 10 and the second waste liquid tank 28 flow through the second three-way valve 34 in sequence and be discharged to the outside.
In this embodiment, the second liquid draining path 320 includes two second three-way valves 34, the two second three-way valves 34 are disposed on a pipeline communicating between the second two-way valve 35 and the second driving member 36, and normally closed ends of the two second three-way valves 34 are respectively connected to the first reaction tank 10 and the second reaction tank 20.
As shown in fig. 3, the first reaction tank 10 is connected to the second waste liquid tank 28 and the normally-closed end of one second three-way valve 34 through the second liquid guide pipe 19, the front tank 201 in the second reaction tank 20 is connected to the second waste liquid tank 28 and the normally-closed end of the other second three-way valve 34 through the fourth liquid guide pipe 25, and the rear tank 202 in the second reaction tank 20 is communicated with the first waste liquid tank 26 and the second waste liquid tank 28 through the third liquid guide pipe 24.
By arranging the first liquid discharge night channel 310 and the second liquid discharge night channel 320, the liquid discharge and cleaning efficiency is improved, and the problem that liquid discharge and cleaning time is long due to the fact that the first liquid discharge tank 26, the first reaction tank 10 and the second reaction tank 20 need to discharge liquid at the same time is avoided.
In other embodiments, the first liquid discharge channel 310 and the second liquid discharge channel 320 may also share the same driving member.
Based on this, the present application also provides a sample analysis device including the liquid path device 100 as described above. The sample analyzer can collect cleaner secondary cleaning waste liquid to be used as the cleaning liquid of the liquid discharging assembly 30, thereby improving the utilization rate of the cleaning liquid and relatively reducing the operation cost of the sample analyzer.
Unlike the prior art, the present application discloses a fluid path device and a sample analysis device. Through setting up first waste liquid jar and second waste liquid jar to collect respectively and carry out the primary waste liquid of wasing and carry out the secondary waste liquid of wasing to the pipeline after the first time washs, and set up the flowing back subassembly and be connected with first waste liquid jar, second waste liquid jar and first reaction tank, make the first reaction tank pass through the flowing back subassembly and discharge raffinate to outside after, the primary waste liquid of wasing that collects in the first waste liquid jar and the secondary waste liquid of wasing that collects in the second waste liquid jar pass through the flowing back subassembly in proper order and discharge to the outside of night circuit device, with wasing the flowing back subassembly in succession, clear away the residue in the flowing back subassembly, and then reduce the part such as liquid valve or the liquid pump that is arranged in the flowing back subassembly of more complicated operating mode and take place ageing or jam risk, still improved the utilization ratio of washing liquid simultaneously, cleaning cost has been reduced relatively.
The foregoing description is only exemplary embodiments of the present application and is not intended to limit the scope of the present application, and all equivalent structures or equivalent processes using the descriptions and the drawings of the present application, or direct or indirect application in other related technical fields are included in the scope of the present application.
Claims (11)
1. A fluid path apparatus, the fluid path apparatus comprising:
the first waste liquid tank is used for collecting primary cleaning waste liquid for cleaning the pipeline for the first time;
the second waste liquid tank is used for collecting secondary cleaning waste liquid for performing secondary cleaning on the pipeline after the first cleaning;
the liquid discharging assembly is respectively communicated with the first waste liquid tank and the second waste liquid tank and is used for guiding liquid to the outside;
the first reaction tank is communicated with the liquid discharge assembly;
after the liquid in the first reaction tank is discharged to the outside through the liquid discharge assembly, the primary cleaning waste liquid collected in the first waste liquid tank and the secondary cleaning waste liquid collected in the second waste liquid tank sequentially pass through the liquid discharge assembly to discharge the liquid to the outside, so that the liquid discharge assembly is cleaned successively.
2. The fluid circuit device of claim 1, further comprising a first fluid circuit and a flow chamber, the flow chamber communicating the first and second fluid waste tanks through the first fluid circuit;
and after counting, cleaning liquid for cleaning the flow chamber is respectively led to the first waste liquid tank and the second waste liquid tank through the first liquid guide liquid path.
3. The fluid circuit device of claim 2, further comprising a second fluid conduit through which the first reaction cell communicates with the drain assembly and the second waste tank, wherein secondary cleaning waste fluid from the second cleaning of the first reaction cell is collected in the second waste tank.
4. The liquid path device according to claim 2, further comprising a second reaction tank and a third liquid guide liquid path, wherein the second reaction tank is communicated with the liquid discharge assembly, and the residual liquid in the second reaction tank is discharged to the outside through the liquid discharge assembly; the second reaction tank is connected with the first waste liquid tank and the second waste liquid tank through the third liquid guide liquid path;
and cleaning liquid for cleaning the second reaction tank is respectively guided to the first waste liquid tank and the second waste liquid tank through the liquid guide component.
5. The fluid path set according to claim 4, further comprising a fourth fluid conducting fluid path, wherein the second reaction tank comprises a front tank and a rear tank, wherein the front tank is communicated with the rear tank through a counting hole so as to perform counting detection when fluid in the front tank enters the rear tank through the counting hole;
the rear tank is connected with the first waste liquid tank and the second waste liquid tank through the third liquid guide pipeline, the front tank is communicated with the liquid discharge assembly and the second waste liquid tank through the fourth liquid guide pipeline, and secondary cleaning waste liquid for carrying out secondary cleaning on the front tank is collected in the second waste liquid tank.
6. The liquid path apparatus according to claim 1, wherein the first reaction tank communicates with the liquid discharge assembly through the first waste liquid tank; the drain assembly includes:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank, and the public end of the first three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first reaction tank, the first waste liquid tank and the second waste liquid tank to flow through the first three-way valve and be discharged to the outside.
7. The fluid circuit device of claim 1, wherein the fluid drainage assembly comprises:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank;
the normally-closed end of the second three-way valve is communicated with the public end of the first three-way valve, the normally-open end of the second three-way valve is communicated with the first reaction tank, and the public end of the second three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first reaction tank to flow through the second three-way valve and be discharged to the outside, and enabling liquid in the first waste liquid tank and the second waste liquid tank to flow through the first three-way valve and the second three-way valve and be discharged to the outside.
8. The fluid circuit device of claim 1, wherein the fluid drainage assembly comprises:
the first liquid draining path is used for sequentially draining the liquid in the first liquid waste tank and the liquid in the second liquid waste tank to the outside;
and the second liquid draining path is used for draining the liquid in the first reaction tank and the liquid in the second waste liquid tank to the outside.
9. The fluid circuit device of claim 8, wherein the first fluid circuit comprises:
a first driving member;
the normally closed end of the first three-way valve is communicated with the first waste liquid tank, and the public end of the first three-way valve is connected with the first driving piece;
a first two-way valve communicating the second waste liquid tank with a normally open end of the first three-way valve;
the first driving piece is used for providing power to enable liquid in the first waste liquid tank and liquid in the second waste liquid tank to flow through the first three-way valve in sequence and be discharged to the outside.
10. The fluid circuit device of claim 8, wherein the second fluid circuit comprises:
a second driving member;
the normally closed end of the second three-way valve is communicated with the first reaction tank, and the public end of the second three-way valve is connected with the second driving piece;
the second two-way valve is communicated with the second waste liquid tank and the normally open end of the second three-way valve;
the second driving piece is used for providing power to enable liquid in the first reaction tank and the second waste liquid tank to flow through the second three-way valve in sequence and be discharged to the outside.
11. A sample analysis device, characterized in that it comprises a liquid path device according to any one of claims 1 to 10.
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| CN114778814A (en) * | 2022-06-13 | 2022-07-22 | 深圳市帝迈生物技术有限公司 | Waste liquid discharge system, sample analyzer and waste liquid discharge method |
| CN114798614B (en) * | 2022-06-28 | 2022-10-28 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer and sample analyzer |
| CN114798581B (en) * | 2022-06-28 | 2022-10-28 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for sample analyzer |
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