CN205413827U - Biochemical analyzer liquid way system - Google Patents

Biochemical analyzer liquid way system Download PDF

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Publication number
CN205413827U
CN205413827U CN201620136140.6U CN201620136140U CN205413827U CN 205413827 U CN205413827 U CN 205413827U CN 201620136140 U CN201620136140 U CN 201620136140U CN 205413827 U CN205413827 U CN 205413827U
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waste liquid
tank
pump
liquid
cleaning
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戴昌武
马德新
赵挺
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Guangzhou Excbio Biotechnology Co ltd
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Guangzhou Excbio Biotechnology Co ltd
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Abstract

The utility model relates to a human blood detecting instrument technical field. Including washing cask (301) and built -in water tank (302) of being equipped with deionized water, characterized by connects built -in water tank (302) and needle inner wall cleaning system by pump and solenoid valve, by pump and solenoid valve connection built -in water tank (302) and washing of needle outer wall and cell cleaning system, connects waste liquid pump drainage system by vacuum pump (207) after rare waste liquid jar (7) and dense waste liquid jar (8) are connected respectively to real empty can (15) and solenoid valve, waste liquid pump drainage system extracts the waste liquid by pump and solenoid valve respectively through self - cleaning subassembly vacuum needle and discharges to waste liquid barrel to and collect the waste liquid of device (17) collecting by the waste liquid and discharge to waste liquid barrel. The utility model discloses having accurate sample, guaranteeing the reliable stability of result, quick sanitization improves testing speed, can handle more samples in the same time.

Description

A kind of biochemical instruments liquid-way system
Technical field
This utility model relates to blood of human body detecting instrument technical field, particularly a kind of biochemical instruments liquid-way system.
Background technology
Biochemical instruments be by the sampling in biochemical analysis, reagent adding, mix, be incubated, colorimetric, result calculate, write the part or all of of the steps such as report completes by imitating manual instrument.During measuring, sampling, colorimetric is all to use the mode recycled.Sampling by stainless steel tube, syringe, valve associating substep controls to draw sample, reagent, is finally discharged in cuvette by sample reagent.Cuvette reacts, measures, obtain testing data, process eventually through computer and obtain result.Owing to test event is numerous, sampling, taking reagent is all to use same stainless steel tube, so need to be required for stainless steel tube inside and outside wall cleaning, and meets cleaning requirement.Cuvette is also to recycle, it is also desirable to clean and cleaning requirement to be met.Certain problem is there is in the technical equipment used at present in terms of stability and accuracy, such as the patent No.: CN200610157238.0 automatic clearing apparatus and method, using cleanout fluid the 1st and the 2nd rank respectively uses a valve to control, and residue 3-6 rank use a valve to control.Waste liquid aspect, the 1st and the 2nd rank are individually retracted to high-concentration waste liquid vacuum tank, and residue 2-6 rank are extracted into low concentration waste liquid vacuum tank.Self-cleaning polishes head 7,8 rank are separately through purge valve control, wiped clean.3-6 rank are automatically cleaned and are individually used a control valve to control, owing to the pipeline pipe resistance of every single order is different, but the pressure that every single order is imported and exported is identical, so 3-6 rank single order or multistage cleaning head can be caused to drip during balance pressure, seriously influence whether stability and the accuracy of test result.
Utility model content
The purpose of this utility model is to provide the biochemical instruments liquid-way system that a kind of sampling simple and practical, accurate, Rapid Cleaning are clean.
The purpose of this utility model is achieved through the following channels:
Biochemical instruments liquid-way system, including equipped with the cleaning bucket 301 of deionized water and inner water-tank 302, it is characterized in that being connected inner water-tank 302 and pin inner wall washing system by pump and electromagnetic valve, inner water-tank 302 and pin outer wall washing and cuvette purging system is connected by pump and electromagnetic valve, after vacuum tank 15 and electromagnetic valve connect dilute waste liquid tank 7 and dense waste liquid tank 8 respectively, waste liquid evacuation system is connected by vacuum pump 207, described waste liquid evacuation system is extracted discharging of waste liquid to waste liquid barrel by pump and electromagnetic valve respectively through automatic cleaning assembly vacuum pin, and the discharging of waste liquid collected by waste liquid aggregating apparatus 17 is to waste liquid barrel.
It is further to be back to reactive tank 20 anabolic reaction dish bath of liquid system by the Incubating Solution in bath of liquid pump 206 abstraction reaction groove 20 through heat exchanger 12 and heater 11.
It is further that described inner water-tank 302 is built with float sensor.
The freezing liquid further extracted in reagent disc 10 by water supply pump 205 is back to reagent disc 10 through heat exchanger 12 and refrigerating plant 13 and forms reagent disc refrigeration system.
Being further that described pin inner wall washing system is connected sampling needle 2 by sampling needle syringe 5, reagent needle injection 6 connects reagent pin 1 and forms.
Being further described pin pin outer wall washing and cuvette purging system forms pin outer wall washing system by cleaning puddler 3, sampling needle 2 and reagent pin 1 in service sink 19, controlled the 4-6 rank deionized water of automatic cleaning assembly cleaning needle by self-cleaning valve assembly 1104 and self-cleaning valve assembly 2105 controls the 1-3 rank dilution cleanout fluid of automatic cleaning assembly cleaning needle, reactive tank 20 cleans cuvette composition cuvette purging system.
Good effect of the present utility model: this utility model biochemical instruments liquid-way system and cleaning method are owing to without sealing radiator, will not cause the hydropenic situation of water tank.Complete machine supplies water reliable and stable, too increases protective measure, reduces the waste situation in terms of client's reagent.This utility model has accurately sampling, it is ensured that result reliable and stable, and Rapid Cleaning is clean, improves test speed, can process more sample within the identical time.
Accompanying drawing explanation
Fig. 1 is this utility model system structure schematic diagram
Fig. 2 is this utility model rinse water water inlet system schematic diagram
Fig. 3 is this utility model pin inner wall washing systematic schematic diagram
Fig. 4 is this utility model pin outer wall washing and cuvette purging system schematic diagram
Fig. 5 is this utility model vacuum system schematic diagram
Fig. 6 is this utility model liquid waste system schematic diagram
Fig. 7 is this utility model reaction tray bath of liquid systematic schematic diagram
Fig. 8 is this utility model light source water-cooling system and concentrated cleaning solutions systematic schematic diagram
Detailed description of the invention
Below in conjunction with Figure of description, this utility model is elaborated:
As shown in Figure 1, this utility model biochemical instruments liquid-way system includes the cleaning bucket 301 equipped with deionized water and inner water-tank 302, it is characterized in that being connected inner water-tank 302 and pin inner wall washing system by pump and electromagnetic valve, inner water-tank 302 and pin outer wall washing and cuvette purging system is connected by pump and electromagnetic valve, after vacuum tank 15 and electromagnetic valve connect dilute waste liquid tank 7 and dense waste liquid tank 8 respectively, waste liquid evacuation system is connected by vacuum pump 207, described waste liquid evacuation system is extracted discharging of waste liquid to waste liquid barrel by pump and electromagnetic valve respectively through automatic cleaning assembly vacuum pin, and the discharging of waste liquid collected by waste liquid aggregating apparatus 17 is to waste liquid barrel.It is back to reactive tank 20 anabolic reaction dish bath of liquid system through heat exchanger 12 and heater 11 by the Incubating Solution in bath of liquid pump 206 abstraction reaction groove 20.Inner water-tank 302 is built with float sensor.The freezing liquid extracted in reagent disc 10 by water supply pump 205 is back to reagent disc 10 through heat exchanger 12 and refrigerating plant 13 and forms reagent disc refrigeration system.Pin inner wall washing system is connected sampling needle 2 by sampling needle syringe 5, and reagent needle injection 6 connects reagent pin 1 and forms.Pin pin outer wall washing and cuvette purging system are formed pin outer wall washing system by cleaning puddler 3, sampling needle 2 and reagent pin 1 in service sink 19, controlled the 4-6 rank deionized water of automatic cleaning assembly cleaning needle by self-cleaning valve assembly 1104 and self-cleaning valve assembly 2105 controls the 1-3 rank dilution cleanout fluid of automatic cleaning assembly cleaning needle, reactive tank 20 cleans cuvette composition cuvette purging system.
Biochemical instruments liquid-way system cleaning method, employing following steps:
A. with the deionized water of pump and electromagnetic valve extraction cleaning bucket 301 to inner water-tank 302, with inner water-tank 302 built with float sensor controlling water level;
B. rinse water is controlled to pin inner wall washing system and pin outer wall washing system and cuvette purging system by pump and electromagnetic valve respectively with two-way, cuvette is cleaned in the deionized water mixing taking the concentrated cleaning solutions entrance self-cleaning valve assembly 2105 concentrating washing bucket 306 by pumping, in service sink 19, clean puddler 3, sampling needle 2 and the inside and outside wall of reagent pin 1, reactive tank 20 cleans cuvette;
C. discharging of waste liquid, the negative pressure produced with vacuum pump 207, divide two-way cleaning needle dilute waste liquid that extraction cleaning cuvette produces and dense discharging of waste liquid to waste liquid barrel through electromagnetic valve, collect the discharging of waste liquid in service sink 19 to waste liquid barrel with waste liquid aggregating apparatus 17.
Rinse water water inlet system, as in figure 2 it is shown, clean the built-in float sensor of bucket 301, detects low level condition alarm, points out user manually to be filled by the deionized water cleaned in bucket 301 in host computer.Inner water-tank 302 has 3 float sensors, judges the general height of its internal water liquid level.The different conditions of 3 float sensors determines whether water intaking valve 101 and intake pump 201 work.When middle float sensor does not floats, water intaking valve 101 and intake pump 201 are energized work, inner water-tank 302 is filled upper float sensor and floats, quit work.Instantly when float sensor does not floats, need to stop new test event, the test event carried out can be continued test, the situation reducing waste reagent occurs.Meanwhile, when cleaning bucket 301 alarm, inner water-tank 302 intermediate sensor does not floats yet, and now ensures that the cleaning remaining deionized water of bucket 301 can meet equally and inner water-tank 302 is filled upper float sensor.Owing to without sealing radiator, the hydropenic situation of water tank will not be caused.Complete machine supplies water reliable and stable, too increases protective measure, reduces the waste situation in terms of client's reagent.
Pin inner wall washing system, as it is shown on figure 3, inner wall washing pump 202 extracts the deionized water in inner water-tank 302, its pressure is relatively big, according to cleaning the water yield its pressure of adjustment.Outlet pressure is relatively big, so outlet can not use flexible pipe, needs the hard tube using hardness higher, it is ensured that do not fall off deformation in pressure more greatly or damage.Inner wall washing pump 202 outlet connects inner wall washing valve module 102, it is made up of 3 electromagnetic valves and a Pressure gauge, Pressure gauge mainly shows the outlet pressure of inner wall washing pump 202, inner wall washing pump 202 is divided into 3 tunnels, respectively one sampling needle syringe 5 of reply and two reagent needle injections 6 by electromagnetic valve.Sampling needle syringe 5 connects sampling needle 2, and reagent needle injection 6 connects reagent pin 1.By this kind of connected mode, cleaned sampling needle 2 and reagent pin 1 by single inner wall washing pump 202 simultaneously.The effect of inner wall washing valve module 102 is when sampling needle 2 and reagent pin 1 draw sample and reagent time, close sampling needle syringe 5 and reagent needle injection 6 and the interface channel of inner wall washing pump 202, ensure that sample and the reagent drawn when sampling needle syringe 5 and reagent needle injection 6 action time are all originated and sample cup and reagent bottle, all pass through sampling needle 2 when discharging sample and reagent and reagent pin 1 is discharged.Sample size is below 50 microlitres, amount of reagent is below 500 microlitres, discharge sample to ensure to draw and draw the accuracy of discharge reagent, the pipeline connecting sampling needle syringe 5 and two reagent needle injections 6 all uses hard tube to connect, and improves pipeline and expands degree of accuracy and the precision causing discharge sample and absorption to discharge reagent.Owing to the impact of water surface tension, sampling needle 2 and reagent pin 1 and reagent pin export less, in general, sampling needle 2 outlet diameter is less than 0.5mm, and reagent pin 1 outlet diameter is less than 1mm.Outlet size is the least, draws the most consistent with the sample reagent amount discharged every time, and repeatability is higher, is conducive to the result of test.
Pin outer wall washing and cuvette purging system, as shown in Figure 4, outer wall washing pump 203 extracts the deionized water in inner water-tank 302, is discharged to outer wall valve cleaning assembly 103.Outer wall valve cleaning assembly 103 is made up of 4 electromagnetic valves and several joint, wherein has 3 electromagnetic valves to control a sampling needle 2 and the outer wall washing of two reagent pins 1, and 1 electromagnetic valve controls two puddlers 3 and cleans.A piece sampling needle 2 and two reagent pins 1 are single movements, so time and the position cleaned are not quite similar every time, so different electromagnetic valves need to be used to control its time cleaned and length.One joint is connected with outer wall washing pump 203 outlet, and a joint is connected to inner water-tank 302, by unnecessary deionized water backflow.One joint connects cuvette self-cleaning valve assembly 1104 and self-cleaning valve assembly 2105.Self-cleaning valve assembly 1104 controls the 4-6 rank deionized water of automatic cleaning assembly cleaning needle, and self-cleaning valve assembly 2105 controls the 1-3 rank dilution cleanout fluid of automatic cleaning assembly cleaning needle.When responding liquid and cleanout fluid in cuvette, vacuum system is siphoned away discharge, and then self-cleaning valve assembly 1104 and self-cleaning valve assembly 2105 energising are opened, and inject dilution cleanout fluid and deionized water, so circulate, cleaned up by cuvette.
Vacuum system, as it is shown in figure 5, vacuum pump 207 air entry connects vacuum tank 15 top, outlet connects acoustic filter 14.Vacuum tank 15 top and bottom connect vacuum-operated inlet valve 108 and vacuum waist valve 107 respectively, when, after system closedown, vacuum-operated inlet valve 108 and vacuum waist valve 107 are opened, can be discharged by the hydrops within vacuum tank 15.The benefit that top is connected with vacuum pump is to greatly reduce vacuum pump 207 to intake the probability of vapour, protects vacuum pump 207.Under vacuum tank side, orientation connects vacuum valve 104, it is ensured that connect dilute waste liquid tank 7 and dense waste liquid tank 8 from vacuum valve 104COM end every time.The position that above-mentioned each parts connect be the hydrops in order to reduce in vacuum tank 15 and reduce the too much water vapour of the interior entrance of vacuum pump 207 and condense water.It is all connected with waist valve, a dilute waist valve 105 and a dense waist valve 106 bottom dilute waste liquid tank 7 and dense waste liquid tank 8.Dilute waste liquid tank 7 and dense waste liquid tank 8 top respectively connect the block 9 that confluxes.The block that confluxes being connected with dilute waste liquid tank 7 extracts the rinse water on automatic cleaning assembly vacuum pin 4-7 rank;The block that confluxes being connected with dense waste liquid tank 8 extracts automatic cleaning assembly vacuum pin 1-3, the reaction solution on 8 rank and band acid and alkali cleansing solution rinse water.When needing to extract the water in cuvette, the vacuum tank 207 with negative pressure is connected by vacuum valve 104 with dilute waste liquid tank 7 and dense waste liquid tank 8, makes dilute waste liquid tank 7 and dense waste liquid tank 8 inside set up negative pressure.Dilute waist valve 105 and dense waist valve 106 are the states closed, so can only be by block 9 and the automatic cleaning assembly vacuum pin of confluxing when dilute waste liquid tank 7 and dense waste liquid tank 8 return to atmospheric pressure, rinse water and reactant liquor in cuvette can have respectively entered dilute waste liquid tank 7 and dense waste liquid tank 8, repetitive cycling, cleans up cuvette.
Liquid waste system, as shown in Figure 6, liquid waste system is divided into two parts.A part of waste liquid is dense waste liquid, extracts automatic cleaning assembly vacuum pin 1-3, the reaction solution on 8 rank and the rinse water of band acid and alkali cleansing solution from dense waste liquid tank 8.It is connected and the connection control of dense waist valve 106 with air by vacuum valve 104, by the mode of dense waste drains pump 210, dense waste liquid is discharged in dense waste liquid barrel 305 again, so dense waste liquid tank 8 is higher than dense waist valve 106, dense waist valve 106 is higher than the entrance of dense waste liquid barrel 305, the most just can ensure that the smoothness of removal waste fluid does not blocks.A part of waste liquid is dilute waste liquid, and dilute waste liquid is also classified into several source, and one is the rinse water extracting automatic cleaning assembly vacuum pin 4-7 rank from dilute waste liquid tank 7.Controlled by the connection of vacuum valve 104 and dilute waist valve 105, then by the mode of dilute waste drains pump 209, dilute waste liquid is discharged to waste liquid aggregating apparatus 17.Two is the waste liquid that puddler 3, sampling needle 2 and reagent pin 1 clean inside and outside wall in service sink 19, confluxes in cleaning waste liquid aggregating apparatus 16, and the waste liquid confluxed flows to waste liquid aggregating apparatus 17 again.Three is that reagent disc 10 condensed water is discharged in waste liquid aggregating apparatus 17.Four is to have part hydrops inside vacuum tank, by vacuum-operated inlet valve 108 and vacuum waist valve 107, internal hydrops is discharged to waste liquid aggregating apparatus 17.What the dilute waste liquid finally confluxed was concentrated is discharged in dilute waste liquid barrel 304 by waste liquid aggregating apparatus 17.The dilute waste liquid of part is also dependent on the mode of gravity and discharges, so need to consider the priority position of each parts during design, it is ensured that when waste liquid is discharged, smoothness does not blocks.
Reaction tray bath of liquid system, such as figure, shown in 7, uses the mode of bath of liquid, the mainly reacting liquid temperature in reaction cup to heat up rapidly, less by the factor of environmental disturbances.Being different from solid directly-heated and air bath, the control mode of bath of liquid is simple, and difficulty of processing is also well below solid directly-heated mode, but more complicated than air bath, and comprehensive these three scheme, the scheme of bath of liquid is best, is also most stable of.Incubating Solution in bath of liquid pump 206 abstraction reaction groove 20, the freezing liquid that outlet connects in heat exchanger 12, with reagent disc refrigeration system carries out heat exchange, after the Incubating Solution of heat exchange reduction temperature is heated to 37 DEG C in heater 11, is again back to reactive tank 20.Reduce temperature through heat exchange, be conducive under varying environment temperature conditions, the temperature of Incubating Solution being controlled.Such as exceeding determined temperature when ambient temperature, if there not being heat exchanger cooling heat exchange, when ambient temperature is too high, Incubating Solution temperature declines not high enough, causes temperature to reduce and can raise on the contrary, finally beyond predetermined temperature.By the way of heat exchanger reduces temperature, requirement can be met in relatively overall situation range of temperature, it is provided that the range of biochemical instruments.
Reagent disc refrigeration system, as shown in Figure 1, water supply pump 205 extracts the freezing liquid in reagent disc 10, freezing liquid is input in heat exchanger, heat exchange is carried out in heat exchanger 12 with the Incubating Solution of reaction tray bath of liquid system, the freezing liquid of exchange post-heating enters in refrigerating plant 13 lowers the temperature, and the freezing liquid after cooling is back to reagent disc 10.Wherein refrigerating plant 13 comprises cooling piece, the cold end of cooling piece and freezing liquid switch, cooling piece hot-side heat dissipation sheet and fan.Cooling piece refrigeration modes simple in construction, quickly, properties of product are reliable and stable, although refrigerating capacity is less than normal, but enough meet the use in biochemical instruments for refrigeration.Cooling down reagent disc 10 by water-cooling pattern, make homogeneous temperature in reagent disc, the specific heat capacity adding coolant is very big, has the interference performance of the strongest environment resistant change.Final temperature can reach and temperature stabilization maintains 2-8 DEG C.
Light source water-cooling system and concentrated cleaning solutions system, as shown in Figure 8, light source water-cooled pump 208 extracts the deionized water in inner water-tank 302, and the port of export connects light source 6, and the deionized water through light source 6 heating is back to inner water-tank 302 again.Owing to light-source system is open type, so needing to separate with other system, and it is higher to the stability requirement of temperature, if variations in temperature is excessive, and the accuracy of meeting strong influence to test result.Concentrated cleaning solutions pump 204 extraction concentrates the concentrated cleaning solutions of washing bucket 306, is mixed by the deionized water that concentrated cleaning solutions enters self-cleaning valve assembly 2105 with outer wall washing pump 203, eventually enters into the 1-3 in automatic clearing apparatus and saves cleaning needle, cleans cuvette.

Claims (6)

1. a biochemical instruments liquid-way system, including equipped with the cleaning bucket (301) of deionized water and inner water-tank (302), it is characterized in that being connected inner water-tank (302) and pin inner wall washing system by pump and electromagnetic valve, inner water-tank (302) and pin outer wall washing and cuvette purging system is connected by pump and electromagnetic valve, after vacuum tank (15) and electromagnetic valve connect dilute waste liquid tank (7) and dense waste liquid tank (8) respectively, waste liquid evacuation system is connected by vacuum pump (207), described waste liquid evacuation system is extracted discharging of waste liquid to waste liquid barrel by pump and electromagnetic valve respectively through automatic cleaning assembly vacuum pin, and the discharging of waste liquid collected by waste liquid aggregating apparatus (17) is to waste liquid barrel.
Biochemical instruments liquid-way system the most according to claim 1, it is characterised in that be back to reactive tank (20) anabolic reaction dish bath of liquid system through heat exchanger (12) and heater (11) by the Incubating Solution in bath of liquid pump (206) abstraction reaction groove (20).
Biochemical instruments liquid-way system the most according to claim 1, it is characterised in that described inner water-tank (302) is built with float sensor.
Biochemical instruments liquid-way system the most according to claim 1, it is characterised in that be back to reagent disc (10) by the freezing liquid in water supply pump (205) extraction reagent disc (10) through heat exchanger (12) and refrigerating plant (13) and form reagent disc refrigeration system.
Biochemical instruments liquid-way system the most according to claim 1, it is characterized in that described pin inner wall washing system is connected sampling needle (2) by sampling needle syringe (5), reagent needle injection (6) connects reagent pin (1) composition.
Biochemical instruments liquid-way system the most according to claim 1, it is characterized in that described pin pin outer wall washing and cuvette purging system are formed pin outer wall washing system by cleaning puddler (3), sampling needle (2) and reagent pin (1) in service sink (19), controlled the 4-6 rank deionized water of automatic cleaning assembly cleaning needle by self-cleaning valve assembly 1 (104) and self-cleaning valve assembly 2 (105) controls the 1-3 rank dilution cleanout fluid of automatic cleaning assembly cleaning needle, reactive tank (20) cleans cuvette composition cuvette purging system.
CN201620136140.6U 2016-02-23 2016-02-23 Biochemical analyzer liquid way system Active CN205413827U (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105499231A (en) * 2016-02-23 2016-04-20 广州埃克森生物科技有限公司 Biochemical instrument liquid path system and method
CN108982894A (en) * 2018-09-20 2018-12-11 武汉纺织大学 A kind of thermostatic type sample introduction needle for level detection
CN110133310A (en) * 2019-05-08 2019-08-16 东软威特曼生物科技(沈阳)有限公司 Biochemical Analyzer
CN114062226A (en) * 2020-07-31 2022-02-18 深圳市帝迈生物技术有限公司 Liquid path device and sample analyzer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105499231A (en) * 2016-02-23 2016-04-20 广州埃克森生物科技有限公司 Biochemical instrument liquid path system and method
CN108982894A (en) * 2018-09-20 2018-12-11 武汉纺织大学 A kind of thermostatic type sample introduction needle for level detection
CN110133310A (en) * 2019-05-08 2019-08-16 东软威特曼生物科技(沈阳)有限公司 Biochemical Analyzer
CN110133310B (en) * 2019-05-08 2023-04-25 东软威特曼生物科技(沈阳)有限公司 Biochemical analyzer
CN114062226A (en) * 2020-07-31 2022-02-18 深圳市帝迈生物技术有限公司 Liquid path device and sample analyzer
CN114062226B (en) * 2020-07-31 2024-04-05 深圳市帝迈生物技术有限公司 Liquid path device and sample analyzer

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